UW folks, don't miss @ishmailsaboor.bsky.social's seminar tomorrow.

Our work, lead by former graduate student Olivia Hon on the BNST, CRF and regulation of different types of fear is finalized as an elife reviewed preprint. elifesciences.org/reviewed-pre...

How do we associate the flavors we experience during a meal 🍽️😋 with postingestive effects like food poisoning 🤢🤮 that arise much later? Our answer in @nature.com this week: Illness signals from the gut reactivate and strengthen flavor representations in the amygdala. 📄: nature.com/articles/s41...

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪 Led by Ling-Xiao Shao and @ItsClaraLiao Funded by @NIH @NIMHgov 📄 Read in @nature.com - www.nature.com/articles/s41... 1/12

Thrilled to share our latest work🚀! Interested in corticostriatal circuits and genetics of anorexia nervosa? Check out our preprint on bioRxiv! www.biorxiv.org/content/10.1...

🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻‍🔬🧠 CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/ Note: full indirects! Please share widely to support women’s health 🙏🏼

Feels odd to post in a normal way about science right now, but I am REALLY proud of this work from the amazing @victoriacorbit.bsky.social from her grad student days in my lab 💪🧠💗 Huge congrats to her, @piantadosisean.bsky.social, & the whole team on this tour-de-force!🎊🎊🎊 Bluetorial on the way...

The NIH BRAIN Initiatives Impacts in Systems and Computational Neuroscience, 2014-2023 https://www.biorxiv.org/content/10.1101/2025.01.30.635684v1

FYI @ahmarilab.bsky.social is still following up on this work if any trainees are interested 👀 Great opportunity to study behavior relevant for OCD🐀🧠 use cutting edge techniques🔬🧬 and have a supportive and encouraging mentor 🫶 Not to mention, Pittsburgh is the best 💛🖤

So happy to see this paper out! Congrats @victoriacorbit.bsky.social and @ahmarilab.bsky.social! Lots of fond memories from running these experiments. The similarity in the behavioral and striatal neural response time course produced by driving M2 inputs was really striking.

Folks at #wcbr- Come check out our symposium on lateral hypothalamus and addiction tomorrow (Wed), 4:30pm in Alpine B. Organised by @marcusweera.bsky.social! I’ll be presenting on #dopamine in lateral hypothalamus and how this changes after methamphetamine self-admin! 🧠 🧪 🧬

NIH memo addresses ‘confusion’ about restrictions imposed by Trump, easing some concerns | Science | AAAS www.science.org/content/arti...

Early start (7:30am symposium) in Grand Ballroom C, for WinterBrain ❄️🧠 I’ll be talking about translational approaches to paranoia, and consilience across rodents, primates, and humans

Registrations are open for the 2nd "Beginners training school on the use of home-cage technologies to monitor rodents". If you are working or interested in working in animal behaviour using home-cage systems, you need to sign up! All costs covered! 17-20 June Bratislava https://buff.ly/3E7MiaW

@kurtfraser.bsky.social and I just had our paper on dopamine, salience, and psychosis accepted @ Am J Psychiatry. We review the history of aberrant salience and the data gathered since: osf.io/preprints/ps...

Be sure to check out new Bruchas lab work from @davidjmarcus.bsky.social and co-authors! An exciting and nuanced story unraveling how endocannabinoid signaling influences behavioral engagement. Make sure to dive into the Supplemental Figures which describes the circuit's role in aversive behavior.

A reminder about our position at SickKids/U of T. Accepting applications until February 15th. Please share widely. can-acn.org/scientist-se...

Very excited for this! Abstract submission is open now and the due date is Februrary 14th, 2025!

🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with: ✨exceptional, brightness ✨phototability ✨and optogenetic compatability. Check out our new preprint: www.biorxiv.org/content/10.1...

Saving the best for last! If you are still at #ACNP2024 stop by grad student Abby Galvez's poster (W48) describing mesolimbic dopamine dysfunction in a selectively bred rat model of bipolar disorder.

If you are still at #ACNP2024 and are interested in the locus coeruleus and/or the amygdala, please stop by my poster from the @mbruchas lab examining how both nodes of this circuit mediate stress-induced anxiety-like behavior tonight (W169)!

Coming soon: We have a Scientist position in the Neuroscience & Mental Health Program at SickKids. Should post details later this week. Stay tuned.

If you’re still hanging around at #ACNP2024 tonight and you’re interested in the insular cortex, interoception, food intake or single-cell seq, stop by my poster (170)!

Hello #ACNP2024 I’m Kasey Girven a Postdoc in the Bruchas Lab at The University of Washington. I study how a neuropeptide S, peri-coerulear projection to the OFC is recruited during repeat exposure to high value rewards 🐭🧀💉 Come listen to my spiel this Wednesday at 3PM in the Grand Sonoran JK 🧠

Hi #ACNP2024! I'm a NIDA K99 postdoc in Michael Bruchas' lab at UW, interested in how endogenous opioids in the basal ganglia promote goal-directed behavior. Come by my poster on Wed (W171) if you'd like to hear more. I'm also on the job market and would love to chat about potential opportunities!

Hey #ACNP2024 attendees, UAB Neurobiology is looking to recruit 4 faculty in the areas of addiction neuroscience, iPSC/organoids, and neurodevelopmental disorders. All searches are open rank. Specific ads are forthcoming, but you can also apply at this link! uab.peopleadmin.com/postings/18636

Sad to miss #ACNP2024 but check out our new studies by the amazing @margestelzner.bsky.social - comparing dopamine vs GABA neurons in the VTA in different forms of learning - our results support an overall re-evaluation of midbrain representation of valence and appetitive motivation (thread)

Acting NIMH Director Shelli Avenevoli, Ph.D. kicking off NIMH section of #ACNP2024 Directors Panel by highlighting job search for permanent NIMH Director- deadline extended to Feb 28, 2025 👀 hr.nih.gov/jobs/search/...

1/ 🧠 Ever wondered how different types of learning coexist in our brains? Spoiler: Sometimes, they don’t! Our new study flips the script on what we thought about memory and learning in Drosophila. Dive in for a surprising twist! 🧵👇 www.science.org/doi/10.1126/...

Lateral septum is really important for many behaviors relevant to neuropsychiatric disorders - and just super cool! Check out our LS panel, co-chaired by me and @ewhizabeth.bsky.social and w/ @superkash.bsky.social and Corey Harwell Wed AM. Image of LS in human 🧠 - details in Alt text #ACNP2024

Headed to @acnporg.bsky.social come see our panel on opioids and depression Monday morning, and DEFINITELY stop by our lab’s postdoc @katybraden.bsky.social poster to learn more!! 🤩🤩💃🏻💃🏻👯‍♂️👯‍♂️👯‍♂️

write up about new cluster hire: research.unc.edu/2024/12/04/c...

Many people have asked me what's the deal with "SIO" in our Addgene vectors (www.addgene.org/Ofer_Yizhar/) - we use these in most of our Cre-dependent AAVs - so here's a brief explanation of how it works.