I haven’t logged onto BlueSky in a while, so I’m way behind on this, but I was happy to play a small part in this cool project with @dschweppe.bsky.social, @keribackus.bsky.social, and @oligopain.bsky.social. See their threads below for the details!

With a few days since it's been out @keribackus.bsky.social @oligopain.bsky.social and I wanted to highlight a few of our favorite aspects of POCA for photocatalytic proximity labeling of DNA, RNA or proteins. (1) POCA builds on standard in situ hybridization and immunofluorescence workflows.

The next iteration of O-MAP targeting genomic loci is now at eLife!! DNA O-MAP enables proximity labeling at specific DNA loci took a ton of work from many lab members and collaborators, so it's really exciting to wrap up this paper with @oligopain.bsky.social! elifesciences.org/articles/102...

We are delighted to announce that Paola Picotti has been awarded the Otto Naegeli prize for biomedical research! otto-naegeli-preis.ch

Excellent visualization of the true distance between the Earth and our moon: #artemis #AGoodPlace Source: www.reddit.com/r/BeAmazed/s...

To better understand the ubiquitin-proteasome system, Suzanne Elsasser, Dan Finley, and the Human Proteostasis Consortium have systematically surveyed its components: www.biorxiv.org/content/10.6... I would encourage you to check out this valuable resource! @harvardcellbio.bsky.social

This morning’s course on studying protein-protein interactions is well on its way at #USHUPO2026! I just wrapped up my talk on AP-MS, and now Lan Huang is talking about crosslinking MS. This afternoon Ling Hao will be talking about proximity labeling as well. @us-hupo.org

Applications are now open for @olgavitek.bsky.social 's May Intitute on computation and statistics for mass spectrometry and proteomics at @northeasternu.bsky.social ! --> computationalproteomics.khoury.northeastern.edu

Unexpected Kid Math Question: how many digits of pi do you need to look at to find the series “67”? Answer: 100 If you’ve been wondering, you’re welcome!

Christmas concert season is here! Tonight I played a concert with the New England Brass Band.

I am looking for a PostDoc to join my group at Genentech to drive the development of proteomics technologies to fuel target and therapeutic discovery and development. Check out the link below! careers.gene.com/us/en/job/20...

Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO! us-hupo.org/Computationa...

Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO! us-hupo.org/Distinguishe...

If you’re at #HUPO2025, be sure to stop by my poster and learn about the latest developments in the BioPlex project!

#HUPO2025 I Our CTDP poster was very well-received! Thank you all for coming! It is free to join CTDP! If you are interested in learning more about #topdownproteomics, please join our talks tomorrow 😀❤️ @proteoforms.bsky.social @nlkproteomics.bsky.social @edhuttlin.bsky.social

Kudos to the organizers (Jennifer Geddes-McAlister, @mlaval6.bsky.social, Marie Brunet) for arranging snow to coincide with the start of HUPO 2025 in Toronto!

I’m at the airport a and ready to fly to Toronto for this year’s HUPO conference. I’m looking forward to talking about AP-MS tips and tricks at tomorrow’s pre-conference workshop on protein-protein interactions and sharing our latest BioPlex results in a poster on Wednesday!

We are ready for Halloween!

Check out this thread from @haopengxiao.bsky.social on his recent paper! I’m happy I was able to help out on what has turned out to be a really cool story.

Hey @haopengxiao.bsky.social - it’s great to see you on BlueSky! Could your new account be a sign you might have something cool to announce soon???? ;-)

Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...

Thoughts from our own Tom Rapoport on the role of basic science in curing disease. magazine.hms.harvard.edu/articles/rev...

Not really an overstatement to say that the test of a free society is whether or not comedians can make fun of the country's leader on TV without repurcussions.

If you’re at #ASMS2025, stop by the Protein-protein and Protein-ligand Interactions section this afternoon and hear how we are leveraging our BioPlex network and AlphaFold structural models for drug discovery!

If you're going to #ASMS2025, don't miss these Gygi lab presentations! You'll learn about TMT, chemoproteomics, GoDig for targeted proteomics, leveraging BioPlex interactions for drug discovery, new instrumentation, and more! @amandalsmythers.bsky.social @asms.org @harvardcellbio.bsky.social

#ASMS2025 is fast approaching, and I'm looking forward to catching up with friends and seeing a lot of great mass spectrometry research. If you’re there, check out my Tuesday talk (TOE 3:10 PM) to learn how BioPlex is enhancing drug discovery!

Harvard's president tells NPR he finds Trump's recent measures "perplexing." "Why cut off research funding? Sure, it hurts Harvard, but it hurts the country," he said, adding that those dollars are awarded to efforts deemed "high-priority work" by the government. https://n.pr/43hPDhX

New work @harvard by Miguel Gonzalez-Lozano @harperlabhms.bsky.social & @ernstschmid.bsky.social in Johannes Walter lab charts structural interactome of endosomes. #XL-MS #Alphafold Funded by @asapresearch.parkinsonsroadmap.org & NIH. Science continues-despite attacks www.nature.com/articles/s41...

NIH's work saves lives—& Trump is gutting it. Straight from D.C. I headed to Seattle Children's to hear from researchers & patients alike about the importance of NIH funding—it's not just about lines in a budget, it's about lifesaving discoveries. We ALL need to speak up to save it.

Multimodal cell maps as a foundation for structural and functional genomics @nature.com @edhuttlin.bsky.social www.nature.com/articles/s41...

This essay from @erinbakerims.bsky.social does a good job summarizing the challenges facing scientists in the current climate and is well worth reading. theanalyticalscientist.com/business-edu...

It’s always fun to open up JASMS and see a familiar face. This time it’s my friend and colleague Jose Navarrete-Perea! @asms.org pubs.acs.org/doi/10.1021/...

Happy New Year!

Welcome to Bluesky, @coonlab.bsky.social!

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

Congratulations to all of the 2025 @us-hupo.bsky.social award winners!

I’m really a trombone player, but every year at about this time I think I should pick up a euphonium and play in a Tuba Christmas….

Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.

I’m looking forward to presenting our latest work combining our BioPlex interaction network with AlphaFold at today’s @ludwigcancer.bsky.social retreat at Harvard and learning more about the great science being done by its members!

@ruth-walks.bsky.social - I just read your bio and noticed you describe yourself as a trombone enthusiast. I can say the same - in fact, I’m headed to a rehearsal right now!

That’s a wrap, we’ve uploaded our version of record for the large scale PISA work led be Jon & co. to @elife.bsky.social : elifesciences.org/articles/95595 Thanks to the reviewers for helping us improve the manuscript, enjoyed the process of developing this resource.

It seems like much of the scientific community has been migrating over here recently, so I'm going to give it a try!