Congratulations to Dr. Ishan Taneja on successfully defending his thesis “Computational Methods for Sampling Alternative Protein Conformations and Modeling Desolvation Upon Protein-Ligand Binding”! He is officially a "Team Forli" graduate!!

Congratulations to eleven Scripps Research scientists named to the global list of #HighlyCited2025 Researchers by @clarivate.com, which recognizes individuals who exemplify research excellence and broad influence across fields including chemistry, microbiology, neuroscience and more.

Excited to announce a preprint describing our software package Meeko! Meeko is a Python package that uses RDKit for receptor and ligand preparation, including protonation, bond order, and connectivity and processing of docking results. It is customizable and suitable for high-throughput workflows.

Excited to share a new preprint from the lab. We show that PTMs like phosphorylation & glycosylation dynamically reshape proteome-wide ligandability in cells, including proteins like KRAS. Great collaboration with the Huang Lab, @forlilab.bsky.social and BMS. www.biorxiv.org/content/10.1...

Huge congratulations to Dr. Althea Hansel-Harris on successfully defending her thesis, "Virtual Drug Discovery for Cancer Biology"! Best of luck as you return to medical school at UCSD — we’re excited to see all the amazing things you’ll accomplish! #dr #futuredrdr

Excited to share our new paper: www.nature.com/articles/s42...! We've compiled the LILAC-DB, a dataset of small molecules bound to membrane proteins at the protein-lipid bilayer interface. (1/5)

Another big publication from @sijiewang.bsky.social this week. Check out our efforts to use mRNA display to screen for covalent binding inhibitors of Staphylococcus aureus serine hydrolases. pubs.acs.org/articlesonre...

A great read for these dire times