We finally made it over here ! And excited to share our new paper on mechanical forces regulating stem cell plasticity in colorectal cancer, involving force transduction via mechanosensitive calcium channels! www.cell.com/cell-reports...

Great opportunity - check it out!👇🤩

Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...

📢Si vous êtes passionné.e par les cellules souches, la régénération tissulaire avec un intérêt pour les pathologies intestinales mais aussi la microfluidique, et vous voulez participer au programme national PEPR MED-OOC, cette offre de thèse est pour vous: www.adum.fr/sujetT?id=67...

🔬 Postdoctoral Opportunity in Biomedical Research. #Organoids & #Organs-on-Chip for #IBD and #Personalized #Medicine at #i2mc in #Toulouse, #France at the crossroads of #stem cell biology, #microphysiological systems, and translational medicine. 👉 Apply before Nov. 1rst at [email protected]

How do cells navigate up gradients of adhesive proteins? 🤔 Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood We show that passive friction directs cells & explains complex trajectories on gradients 👉 www.nature.com/articles/s41...

Ever wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11) 🔗 www.biorxiv.org/content/10.1...

The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social www.cell.com/developmenta...

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients. More here: elifesciences.org/reviewed-pre...

Our paper is on the cover of @cp-devcell.bsky.social . Image: embryonic murine salivary-gland explants stained for fate determinants; p63 (cyan) and HES1 (yellow). Thanks to everyone involved. doi.org/10.1016/j.de...

Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

Three-Year Funded Postdoctoral Position to study organelle architecture in mammalian oocytes – Terret-Verlhac Lab, CIRB, Collège de France (Starting 2026). For more information, please contact: [email protected]

🚨 New paper out in @pnas.org! 🚨 We show that self-generated gradients allow heterogeneous cell mixtures to co-migrate efficiently over long distances —while optimizing their physical interactions! (See below for 🧵) www.pnas.org/doi/10.1073/... 🧪

Synthetic materials accumulate damage with every mechanical challenge. Epithelial tissues are regularly loaded, yet healthy epithelia rarely rupture. Why? We are @epmech.bsky.social and @baldaufsci.bsky.social and in this thread we introduce you to cyclic loading. bsky.app/profile/epim...

Mechanical forces shape the developing brain 🧠💥 Compression from high cell density doesn’t just squeeze cells - it compromises mitotic fidelity! New preprint on how mechanics impact neural development from Veronique Marthiens & co-authors @institutcurie.bsky.social @cbitoulouse.bsky.social 🧠🔧👇

🧵Just out ! We reveal how 4 branched epithelia—mammary, lacrimal, salivary & prostate—use a conserved YAP–Notch–p63 circuit to self-organize during development & regeneration. Here’s the story👇 authors.elsevier.com/c/1lM285Sx5g... Work done in @frelab.bsky.social at ‪ ‪ @institutcurie.bsky.social

My first experience at a GRC- excellent talks & stimulating conversations. Thanks to everyone to who stopped by my poster- your feedback were incredibly valuable to me. And of course, infinite gratitude goes to @yap-lab.bsky.social, an exceptional mentor and support throughout my journey!

A highlight of our recent story!

Students (Master's/PhD), do not miss this fantastic Developmental Biology course of @sorbonne-universite.fr and @institutcurie.bsky.social - It is FREE and open to international students, however, room and board + travel are not included. training.institut-curie.org/courses/deve...

Enjoying great science and stunning alpine views at the GRC on Cell Contact & Adhesion in Les Diablerets 🇨🇭⛰️ Proud of our PhD students Dhriti and Vishnu for their terrific work - posters and talks full of exciting insights! #CellContactAndAdhesionGRC #CellBiology #PhDLife #LesDiablerets

Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!

Thank you @naturemethods.bsky.social for highlighting our recent paper on "Spatial Mechano-Transcriptomics" in your April Issue: www.nature.com/articles/s41... www.nature.com/articles/s41...

We are excited to share our recent preprint on how tissue spreading guides extracellular matrix changes during early morphogenesis @gurdoninstitute.bsky.social

I am excited to share my latest Postdoctoral work @cp-cellstemcell.bsky.social @cellpress.bsky.social (dlvr.it/TK2Fzl), in which we reveal that goblet and Paneth cells aren’t fixed lineages but represent dynamic states influenced by local cues. Here's a walkthrough of what we found (🧵)....

REPOSTING this here just to officially leave "the other place" Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social nature.com/articles/s41...

🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻‍🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)

🚨 Abstracts are due next week! 🚨 Submit your abstract to give a talk or poster at YEN 2025 by the 12th April! Share this opportunity with dev bio and stem cell PhD students. The conference is FREE and full of great science. We are looking forward to seeing you there!

Are postdocs the rarest species, or is it just me? We have two funded positions—apply now and join us on these exciting projects! #zebrafish #zebrafishcareers #iPSC #devbio #regeneration

Are you passionate about live-imaging microscopy? Do you have a special talent for working with iPSCs? Or are you simply a zebrafish aficionado? 🐟 We have 2 funded postdoctoral positions in our lab (cbi-toulouse.fr/eng/equipe-b...). Join us and apply now! Please spread the word 🙏

Interested in the cell biology of the nucleus? Join us for this unique exciting meeting that covers everything from nuclear biophysics and mechanics to signaling and evolution😍 amazing speaker list and more will be selected from abstracts 🤩

Happy to share our new publication in @naturephysics.bsky.social on life and death of eliminated cells! Great collaboration between our CAM team and Doostmohammadi's. Special congrats @lakshmib02.bsky.social and Siavash Monfared! 🎉 www.nature.com/articles/s41...

Happy New year✨️🌟🤗 inclusion, stars, interactions and fantastic projects✨️🌟👍🎊. Last article in 🇨🇵 on inclusion thanks so much Lena Saoui. lopinion.com/articles/por...

Very happy to share my first story in @levayerr.bsky.social lab, where we show that localized apoptosis drives JNK-dependent developmental delay to ensure global tissue size robustness 🪰

❗️Our new paper "Local activation of Cxcl12a signaling controls olfactory placode morphogenesis in zebrafish embryos" is out 👇 bioRxiv.🙏 Thanks so much to all coauthors: fantastic people😍🤩 ✨️fantastic work. Mathematical modeling to understand morphogenesis. Get in touch if interessed, more to come😉

🚨🚨🚨 Call is now open!!! Deadline approaching... Wanna become our new beloved colleague and be part of a stimulating (and friendly) scientific community ??? We are perfectly located in beautiful Paris with exciting work environment and state-of-the-art core facilities APPLY 👇👇👇👇👇

Happy holidays 🎄 and #FluorescenceFriday with this festive mouse colonoid! Work of Amalia Ferran, new PhD student in our team @cbitoulouse.bsky.social 🙏🐭🔬

❗ANNOUNCEMENT❗ YEN 2025 Conference will be held at @crick.ac.uk on the 19th May 2025. We are looking forward to another exciting line-up with Nicolas Rivron, Maud Borensztein and Peter Rugg-Gunn. This year will see a return of the YEN Image Competition so follow for updates. Share for #YEN2025!

Curious how the gut epithelium resists mechanical stress while maintaining the barrier? Don’t miss our talented PhD student Vishnu Krishnakumar’s mini-talk on Dec 17, 10:25 AM at #ASCB2024! Check out his poster P2506 too. Thanks to #SBCF, @frm-officiel.bsky.social & @cnrs.bsky.social for support!

GDR AQV and GDR IMABIO @gdrimabio.bsky.social are joining forces to organise a workshop on new quantitative imaging stategies. Thursday January 26 2025 at Institut Jacques Monod @IJMonod. Many slots for oral communications are still available! newmic4cellbio2.sciencesconf.org