☕Yashinskie, Zhu et al show that #p53 activation triggers increased synthesis and accumulation of phospholipids, with enhanced activation of #autophagy and lysosomal catabolism programmes and increased reliance on lipid headgroup recycling. @lydiafinley.bsky.social bit.ly/4asbwO3

One more thing- here, together with amazing human being, friend & stellar physician scientist Abby Xie, we identify a new function of the TCA cycle, which is citrate clearance, now online at @cellpress.bsky.social: www.cell.com/cell/fulltex...

Polyamine-dependent metabolic shielding regulates alternative splicing @nature.com @cicbiogune.bsky.social www.nature.com/articles/s41...

A big chunk of my postdoctoral work on cell-state dependent metabolism is now out at @cp-molcell.bsky.social: www.cell.com/molecular-ce... 1/

I'm excited to share our latest story from the @lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/

In-cell architecture of the mitochondrial respiratory chain | Science www.science.org/doi/10.1126/...

Structure of human mitochondrial pyruvate carrier - what a milestone by the wonderful Dan Ma's lab from Westlake! Using Xudong Wu's expertise in nanoantibodies, they capture MPC during transport, revealing its pseudo-symmetric model and alternate opening mechanism with functional cardiolipin. Bravo!

We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. www.jobs.cam.ac.uk/job/50597/ @ims-mrl.bsky.social Please RT. Please email if interested.

Pleased to share our @cp-cellmetabolism.bsky.social forum on why we think standard cell culture practices deserve more consideration. How we culture cells has implications for cell metabolism & beyond! With @jasonrcantor.bsky.social @joycelyntan.bsky.social authors.elsevier.com/a/1klN65WXUl...

happy to share our forum now online @Cell_Metabolism! fun for us (Guy & myself) to collaborate with @dfazakerley.bsky.social, Joycelyn, & Sam in putting together what we hope will be a useful piece for the broad metabolism community re: in vitro modeling! www.cell.com/cell-metabol...