Now in @dev-journal.bsky.social: Researchers in the Tsiairis lab have discovered how Hydra cells decide to form stinging tentacles or an anchoring foot, revealing key rules of body patterning. www.fmi.ch/news-events/...

📣 EU-LIFE brings together the voices of 16 leading #biotech #innovation experts, including scientists, CEOs, investors & #TechTransfer professionals, who all agree on one thing: 𝗘𝘂𝗿𝗼𝗽𝗲’𝘀 𝗰𝗼𝗺𝗽𝗲𝘁𝗶𝘁𝗶𝘃𝗲𝗻𝗲𝘀𝘀 𝗱𝗲𝗽𝗲𝗻𝗱𝘀 𝗼𝗻 𝘀𝘁𝗿𝗼𝗻𝗴, 𝗹𝗼𝗻𝗴-𝘁𝗲𝗿𝗺 𝘀𝘂𝗽𝗽𝗼𝗿𝘁 𝗳𝗼𝗿 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆-𝗱𝗿𝗶𝘃𝗲𝗻 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵. ➡️ doi.org/10.5281/zeno...

With the FMI Annual Meeting underway last week, admin staff & some retired colleagues enjoyed an excursion to Broc & the district of Gruyère. With cheese-making, a tasty lunch & a sweet finale at a chocolate factory, it was a chance to strengthen ties and enjoy time together.

Last week in Davos, our Annual Meeting gathered the FMI’s scientific community, Novartis colleagues & the Scientific Advisory Board. Highlights included the FMI science prize ceremony, honoring creative thinking, outstanding PhD theses & exceptional postdoc studies 🏆 www.fmi.ch/news-events/...

Congrats to the mixed football team FMI + @biozentrum.unibas.ch for bringing home a coveted trophy at the tournament organized by @eth-bsse.bsky.social ⚽ Fantastic grit and teamwork!

Truly honored (and a little overwhelmed) to see our work featured in The Transmitter's "This Paper Changed My Life." Huge thanks to @neural-reckoning.org for the kind words - and to our amazing community that keeps pushing spiking neural network research forward 🙏

Very grateful to the Ruth Chiquet Prize committee for recognizing our efforts and to the FMI community for their invaluable support in this project.

Another FMI Annual Meeting is in the books! After a night of follies and plenty of dancing, today brought the announcement of our internal prize winners, more inspiring talks, and a vibrant poster session. Already looking forward to next year! 🙌

This year's Ruth Chiquet Prize goes to @solygamagda.bsky.social, who sent a video message, for her work on how the brain detects sensory mismatches. Read more at: www.fmi.ch/news-events/...

The Max Burger Prize 2025 goes to Josip Ahel (@aheljo.bsky.social), Aparna Pandey & Michaela Schwaiger for adding a key piece to the puzzle of how cells protect the DNA from “jumping genes.” Read more at www.fmi.ch/news-events/...

This year’s Ed Fischer Prize goes to Francesca Masoni (@schubelerlab.bsky.social) for her PhD on chromatin organization—revealing how the ISWI chromatin remodeler subcomplex NURF positions nucleosomes to safeguard genomic boundaries & gene regulation. Read more at www.fmi.ch/news-events/...

After a successful poster session yesterday night, day 2 of the FMI Annual Meeting featured inspiring talks from our scientists in the morning, followed by alpine adventures—including several hikes. Tonight, we continue with a gala dinner and the traditional follies 🎉

To find out more about this work, we spoke to first authors Jaroslav Ferenc & Marylène Bonvin, and corresponding author Charisios Tsiairis, Group Leader at the Friedrich Miescher Institute for Biomedical Research @fmiscience.bsky.social in Basel, Switzerland: journals.biologists.com/dev/article/...

Hydra body axis balance: a fight between two transcription factors This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis: journals.biologists.com/dev/article/...

I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role: www.fmi.ch/education-ca...

This year's FMI Annual Meeting kicked off today in Davos with exciting talks from our scientists! Plus, we were thrilled to host Jan-Michael Peters (@impvienna.bsky.social) for a plenary lecture on how a protein complex called cohesin folds DNA into loops—shaping how our genes work 🧬

contact me or @csoneson.bsky.social if you want more details

📣The Turco group is seeking a computational biologist to analyze large omics datasets. Work on cutting-edge 3D organoid models of the human placenta and be embedded in our Computational Biology Platform (part of @sib.swiss). Apply here: www.fmi.ch/education-ca...

Let's not forget to acknowledge my partners in crime: @seadaisy.bsky.social, Laurent Gelman from @fmiscience.bsky.social, Pascal Lorentz and Loïc Sauteur from @unibas.ch, and Tom Lummen from @ethz.ch !

This week we hosted Transmitted Light Microscopy courses at the FMI—two great days with Novartis colleagues & the Microscopy Network Basel! Lectures + a temporary lab set up by our expert @laureplantard.bsky.social with microscopes from ZEISS, Leica, Nikon & Evident 🔬

Today Lucía takes you by the hand and walks you through the entire ERC #evaluation process — from panel selection to interview. Learn who reviews your #proposal, how decisions are made, & how to best increase your chance of success. 👇 #research #funding #grant #AcademicSky

The FMI just opened a position for a junior group leader in structural biology. Check it out. Join us!

Join us on November 4th! The winners of our best short talk awards will be telling their research on the @isscr.org stage! Thank you @stemcellreports.bsky.social for co-organizing this webinar!

with major support from the @fmiscience.bsky.social Core Facilities

We are hiring-join us!

!!! Join us !!!

Become our colleague at @fmiscience.bsky.social! The FMI is a very special place to start your lab: a vibrant international institute with world-class research groups and facilities, core funding, fantastic trainees, great colleagues😅, and a collegial culture. Get in touch if you're interested!

🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

📣 It is my pleasure to announce our recent review with Margherita on the current approaches, challenges, and perspectives in studying human maternal-fetal interface using in vitro models www.cell.com/cell-stem-ce... 🚀✨️

In a Review just published in @cp-cellstemcell.bsky.social, @vladbndk.bsky.social and Margherita Turco explore how stem cell and organoid models can be used and combined to better study the maternal–fetal interface. A 🧵

If you like transcription regulation and its mechanisms, this WIP list is for you. I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list. go.bsky.app/8vTgeXB

In a new study, FMI researchers show that two enzymes—KDM2A and KDM2B—act as safeguards in eggs, preventing excessive DNA methylation at gene regions. Without them, abnormal methylation is passed to embryos, repressing genes needed for early development. www.cell.com/developmenta...

🇨🇭 Postdocs in Switzerland: Don’t miss the 14th Basel Postdoc Network meeting! 📅 8–10 Oct 2025 | Klosters Connect with peers across life sciences, chemistry, medicine, engineering & physics, explore careers & share research. Extended deadline: register by 7 Sep 👉 baselpostdocnetwork.unibas.ch

🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...

One year in our new home, we welcomed 500+ Novartis colleagues last week for our Open Day. Under the motto United by Science, our visitors explored how FMI research, tech & partnerships fuel biomedical discovery. Check the story for event pics 👇 www.fmi.ch/news-events/...

Our Open Day for Novartis was a great success! 🎉 Many @novartis.bsky.social colleagues joined us today to explore our science, meet our researchers & enjoy food trucks. Huge thanks to all volunteers and everyone who stopped by — here’s to more connections and collaborations!

I am happy to finally share this preprint of my PhD project in @guillaumediss.bsky.social lab at the FMI in Basel. We used ddPCA to map the genetic architecture of the entire human bZIP interaction network. www.biorxiv.org/content/10.1... Thanks to all our co-authors for the great collaboration!

The last day of lectures at #LISH25 starts with Gustavo Medeiros presenting applications of light sheet microscopy to #organoid research. @priscaliberali.bsky.social lab. Gustavo is a physicist and a creative artist and the walk-up song delivers that message. Video in thread.

A little piece of our history has a new home! The iconic logo that graced the old FMI building on the Rosental campus is now in the lobby of our new home on the Novartis campus, just across the river in Basel. A symbol of our journey and memories 🫶🧬

We’re looking forward to welcoming @juliabatki.bsky.social as a new Junior Group Leader in Multicellular Systems! Excited for the fresh perspectives and expertise the Batki lab will bring to our research community 🧬

🔥Would you like to explore the principles behind collective behavior in biological systems, from cells to communities? Don't miss this EMBO | EMBL Symposium! #EESCollectivity

Preprint by the Thiel, Heller&Chao labs w/1st author Reto Lang "Stress granules formed during different RNA virus infections show remarkable plasticity &substantial virus-specific differences in their formation&composition" @biorxivpreprint.bsky.social buff.ly/vU7Tdg6 @profvolkerthiel.bsky.social

Huge congratulations to Clara Baader on successfully defending her PhD this week! Her research explored how mechanical forces and biochemical signals coordinate to guide intestinal development and repair 🎓

We’re excited to share that ez_zarr now supports Zarr v3! 🚀 Huge thanks to @mbstadler.bsky.social & @csoneson.bsky.social who took on the challenge of creating this open-source tool for fast, programmatic access to OME-Zarr file sets + easy plotting 📊 📄 joss.theoj.org/papers/10.2110… (1/3)

Excited to share our latest preprint. www.biorxiv.org/content/10.1.... Lead by Lukas, we investigated multiple ways of assessing a TF's sensitivity to chromatin based on genome-wide binding profiles. The developed methods allowed us to quantify chromatin sensitivity across tested TFs.

🌟 Postdocs – want to become a PI? Apply for PIs of Tomorrow 2026 at the LS2 Annual Meeting (Feb 11–12, Zurich). Prizes, feedback, and networking: annual-meeting.ls2.ch/2026/special... Deadline: 5 Oct 2025 🔗 form.jotform.com/211792813615... #Career #PIsOfTomorrow #Postdoc

Now out in @cp-molcell.bsky.social: Researchers in the @schubelerlab.bsky.social have uncovered new clues about how transcription factors help cells choose their fate by revealing patterns in DNA binding. This insight could improve understanding development and disease. www.fmi.ch/news-events/...

Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....

Excited to share that my first-author publication from my PhD on the interplay of p53 with cofactors on chromatin is now online in Molecular Cell @cp-molcell.bsky.social : www.cell.com/molecular-ce... Nucleosomes filter cofactor access to p53 - USP7 can bind whereas E6AP-E6 fails to form a complex.

Join leading scientists in tissue engineering and in vitro disease models at our conference in Serbia. Hear from @fmiscience.bsky.social ‬and experts from @utoronto.ca, @columbiaseas.bsky.social‬ plus more. Register now: go.nature.com/3HUNLU9 #TissueEngineering #STEMConference #Academicsky