Great @bigtencrc.bsky.social summit today. Advancing cancer research collaboration across the growing BigTen (now 18!) team. Honoring colleagues including Dr. Bailey and meeting new members.

Excited by this new opportunity at the Carbone Cancer Center @uwhealth.bsky.social and know Dr. Uboha will be an excellent leader of our clinical trials program! www.linkedin.com/feed/update/...

Look at Darian, research coordinator @uw Carbone presenting this trial

Excited to see this BigTen met TNBC study @bigtenplus.bsky.social published. Although primary endpt not met, addressed an important question and some interesting observations for future. link.springer.com/article/10.1...

In women with node-positive breast cancer whose nodes became free of disease after neoadjuvant therapy, regional nodal irradiation did not reduce breast cancer recurrence or improve survival. Full results from a phase 3 trial: nej.md/4dM6LjD #MedSky #Oncology

Key take homes for #breastcancer at #ASCO25 (3) *Triplet PI3k (Inavo)+fulv+palbo improved OS in MBC in those with early progression on adjuvant AI (need early NGS for PIK3CA *TDXd (plus pertuz) improves PFS in 1L HER2+ MBC. Will watch for PFS2/OS in future. Key ? is how to integrate PATINA in ER+

Key take homes for #breastcancer at #ASCO25 (2) *1st PROTAC (vepdeg) improves PFS in mESR1 MBC *Monitoring ctDNA for ESR1 mutations in MBC w early change to SERD (cami) improves PFS, longer term outcomes important *Dose escalation of abema improves tolerance (TRADE)

Key take homes for #breastcancer at #ASCO25 (1) *OFS/AI in high risk preM women reduced recurrence. OS not met (at 15 yrs) but w/o detriment to non-cancer OS *Vasomotor AEs from ET effectively reduced w elinzanetant *Select stage 1-3 HER2+ BC may not need carbo *SG + pembro is a new 1L TNBC option

What a great surprise from the breast med onc clinic team today! Made my day-so thoughtful.

Meet Mahua Dey — neurosurgeon, scientist and innovator at @uwmadison.bsky.social. She's leading the charge against glioblastoma, one of the deadliest brain cancers. Her lab's personalized therapeutic vaccine, GIFT-7, has shown remarkable success in preclinical trials.

Former Univ of Wisconsin heme/onc fellow!!

Just talked about these results with 2 pts in 2 weeks. Improved outcomes with ET in ERlow breast cancer, unless pCR to Neoadj chemo. ascopubs.org/doi/10.1200/...

NIH layoffs delay research benefiting cancer patients, and celebrity cancer news is often missing important information, and more news from Cancer Today magazine: www.cancertodaymag.org/cancer-talk/...

Loving the @uwhealth.bsky.social Carbone Cancer Center Community day for @uwbadgers.bsky.social science days. Attempted Brain surgery (sticking to med onc), attended panel on working w research advocates, ice cream and more!

Working with an interdisciplinary team, we have developed a website to communicate how the White House's proposed cuts to health research would cause losses of $16B and 68,500 jobs. Find out how your community may be impacted. Explore more at SCIMaP: scienceimpacts.org a 🧵

The resignation letter should be seen by all. A reminder to keep speaking up/advocating for science.

Peter Marks forced to resign www.bbc.co.uk/news/article...

Had a great team dinner with these amazing @uwhealth.bsky.social breast nurses, MAs, pharmacists, APPs and oncologists last night! Fills the cup. @marina-sharifi.bsky.social

What a great day at our 2025 retreat- celebrating and socializing with colleagues and planning for the upcoming year. @marina-sharifi.bsky.social @noelleloconte.bsky.social @joshlangmd.bsky.social

Now online in Cancer Discovery: High-Purity Circulating Tumor Cell RNA Sequencing Identifies #ProstateCancer Lineage Phenotypes Prognostic for Clinical Outcomes - by Marina Sharifi, Jamie Sperger, Shuang Zhao, Joshua Lang, and colleagues doi.org/10.1158/2159...

Thanks to the outstanding Heme/Onc and Hospice and Palliative Medicine fellows who are committed to high quality care and ongoing learning! @uwhealth.bsky.social

Publication by @ascocancer.bsky.social on academic medical oncology. Makes me wonder- how do we encourage more transparency among institutions to set these standards ? ascopubs.org/doi/10.1200/...

Grateful to @uwbadgers.bsky.social women’s basketball team for hosting #breastcancer survivors and researchers at the game this weekend!

Moody lab pic of me in a grim piece on this wrecking ball for biomedical research. To explain “indirects": If research is a restaurant, direct costs cover ingredients & cooks' wages. Indirect costs cover kitchen, light & heat, furniture, bookkeeper etc. Lose one, the other follows! wapo.st/3Q9DrIH

Last but not least, Dr. Sharifi presenting on Genomics/Precision Medicine #SABCS24 abstracts. @uwhealth.bsky.social

What a great day of #SABCS24 @sabcs.bsky.social updates in Wisconsin co-hosted by UWCarbone, MCW and WI Association of Heme/Onc.

Excellent #SABCS updates by Drs. Gradishar and @rmoregan.bsky.social at the 8th (or 10th?) Annual WI conference. Enjoyed catching up and grateful for these mentors and friends.

Dr. Bethany Anderson eloquently presents #SABCS24 radiation abstracts at the WI Best of SABCS. Key theme is individualization based on cancer features and pt preferences. @uwhealth.bsky.social

Dr. Anna Beck from @uwhealth.bsky.social discusses @sabcs.bsky.social surgery abstracts at the WI annual update. Great to see individualization of surgery to de-escalate when appropriate

Trends in Well-Being and Burnout Among U.S. Oncologists: Challenges and Solutions @ascocancer.bsky.social @acochran12733.bsky.social @jrgralow.bsky.social ascopubs.org/doi/10.1200/... @oncoalert.bsky.social

Two key questions in my mind- 1) does Her2 low expression really matter? 2) do we develop new guidelines for pathologists report this consistently?

The house cancer caucus is led by Deb Dingell (D-MI) and Deb Wasserman Schultz (D-FL) Mike Kelly (R-PA) and Brian Fitzpatrick (R-PA)- please ask to end pre-auth, keep telehealth, expand cancer funding & keep #NIH working!! #medsky #cansky #oncsky @wassermanschultz.house.gov @repdingell.bsky.social

Usually I stick to oncology info, but seriously Rolling my eyes at the #tiktok notice promoting Trump. Propaganda at its core.

Learning about effective advocacy for #cancer at Leaders in Oncology mtg thru ACCC and @ascocancer.bsky.social.

Congratulations to my statewide WI colleagues on publication of this ph2 study- closed early but always learning from science. www.sciencedirect.com/science/arti... @uwhealth.bsky.social

This week's cover and editorial @thelancet.bsky.social on mis- and disinformation's impact on public health www.thelancet.com/journals/lan...

"Without clinical trials, cancer treatment would always remain the same" [Nov 3, 2012] - via @TomBeer in @OncologyTimes ow.ly/fmaKk #ClinicalTrials #ctsm

I was born in rural Iowa with many family members who have been impacted not only by access to healthcare but incredibly poor quality of care. Systems matter in medically under resourced communities and these systems are being bankrupted. @ascopost.bsky.social

Flashbacks with flashcards as I quiz my daughter for AP Chem. #oncology colleagues- remember these?

x X has ~18m daily USA users. @bsky.app, ~1.5m. Is it worth 20 MINS a day to proactively recruit and bring your friends, neighbors,relatives, businesses, anyone who is or could be a user, to @bsky.app? If Bluesky ends up with more users than the others, you destabilize musk, zuck, trump.

Dr. @noelleloconte.bsky.social weighing in on this important statement by the surgeon general on #alcohol and #cancer based in part on the work of Dr. LoConte with @ascocancer.bsky.social

Extending thanks to all my colleagues, nurses, pharmacists and staff working today to help those hospitalized with #cancer. Let’s hope for a new year of many advances thru research.

What a great line-up of speakers with guests @rmoregan.bsky.social & Bill Gradishar, plus UWCarbone faculty Drs. Marina Sharifi, Anna Beck & Bethany Anderson at the annual Wisconsin Best of #sabcs24 on Feb 1st. Co-hosted with Medical College of WI and WAHO in Milwaukee. Join us! @sabcs.bsky.social

🌟 Excited to speak at Total Health’s 2025 University of Kansas Cancer Center #BreastCancer Year in Review! 🌟 📅 When: Saturday, February 22, 2025 🕒 Time: 8:35 AM to 3:10 PM 📍 Where: Marriott Kansas City Overland Park

Congrats to all #BigTen cancer researchers who presented at #SABCS24. Our team managed to visit some of your posters, but there were so many others at the meeting. Wish we could have visited all! @rutgerscancer.bsky.social

Enjoyed spending the evening with the UW team at #SABCS24.

Pictures!!

Excited to see research from University of Wisconsin Carbone Cancer Center’s Dr. Anna Beck on LCIS incidence increases associated with guideline changes to mammograms at age 40. Important for high risk screening & prevention. #SABCS24

Exceptional discussion about new concepts at the BigTen CRC meeting at #SABCS. Plus a gathering of colleagues who are now great friends!

Proud to have research coordinator and med school candidate, Darian Louthan present a BigTen CRC ph2 study of continued ET + alpelisib in mPI3k MBC. @rmoregan.bsky.social @rdillinger.bsky.social UWCCC