The ASCO Post
@ascopost.bsky.social
📤 1428
📥 964
📝 217
News and views from the world of clinical oncology and hematology
🧠 Early data in glioblastoma: A single injection of a herpes simplex virus triggered sustained antitumor T-cell responses, with immune infiltration linked to clinical benefit. ✍️ Kai Wucherpfennig, MD, PhD & E. Antonio Chiocca, MD, PhD 🔗
https://ow.ly/wM8r50YhGoA
about 13 hours ago
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💻 Explore the new ASCO AI in Oncology Clifford A. Hudis, MD, FACP, FASCO, shares how this new digital hub delivers broad coverage of AI in cancer care—featuring curated AI research, clinical insights, and expert perspectives for oncology professionals.
https://ow.ly/bx5P50Yhg0G
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Clifford A. Hudis, MD, FACP, FASCO: ASCO AI in Oncology
https://ow.ly/bx5P50Yhg0G
1 day ago
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🫀AI meets cardio-oncology. The ONCO-ACS risk model improves prediction of CV death, MI, and ischemic stroke in patients with cancer and heart disease. A step toward more personalized secondary prevention. Senior author: Thomas F. Lüscher, MD 🔗
https://ow.ly/qVGS50Yfbxq
6 days ago
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In an interview with American Society of Clinical Oncology CEO Clifford Hudis, Dr. Hudis introduces ASCO AI in Oncology (
ascoai.org
), the new digital platform dedicated to understanding how AI is impacting cancer care.
https://ascoai.org/articles/2026/02/introducing-asco-ai-in-oncology/
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Introducing ASCO AI in Oncology: A Conversation With Clifford A. Hudis, MD, FACP, FASCO
https://ascoai.org/articles/2026/02/introducing-asco-ai-in-oncology/
8 days ago
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📢 ASCO in collaboration with Conexiant today announced the launch of ASCO AI in Oncology (
https://ow.ly/tiak50Ycj11
), a new digital destination focused on delivering curated content and education around the evolving role of AI in cancer care.
https://ow.ly/WqaG50Ycj10
9 days ago
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🏥 American College of Surgeons released its annual National Cancer Database report, showing a major rise in neoadjuvant systemic therapy across cancer types—helping shrink tumors, guiding treatment decisions, & enabling less invasive surgery. Read key takeaways 👉
https://ow.ly/iqfp50Y8NI7
15 days ago
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🗣️ Matthew Strickland, MD, discusses phase IIb TERRIFIC data evaluating neoadjuvant tislelizumab + chemoradiotherapy vs chemo(radio)therapy for patients with locally advanced gastric/GEJ adenocarcinoma. 🎥 Watch the video:
https://ow.ly/LcNf50Y7JNK
17 days ago
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🚨 Cancer workforce shortages threaten patient access & research progress, according to a report from the President’s Cancer Panel. 🔹Report by Mitchel S. Berger, MD & Carol L. Brown, MD Learn about recommendations for addressing shortages 👉
https://ow.ly/nEeA50Y5oX2
21 days ago
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🚨 New American Cancer Society study: States that limit/don’t allow short-term health plans saw delays in timely cancer treatment initiation after diagnosis. Health insurance is a major factor in survival. #CancerCare ✍️ Jingxuan Zhao, PhD 🔗
https://ow.ly/kPMk50Y4UpZ
22 days ago
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🧠 Targeted therapy shows activity in aggressive meningiomas. In a phase II Alliance trial, abemaciclib slowed tumor growth in patients with NF2 mutations or CDK pathway–altered meningiomas. Priscilla Brastianos, MD 🔗
https://ow.ly/4ZCp50Y3UoA
23 days ago
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🕊️ “A Battle With My Blood” - the final essay by Tatiana Celia Kennedy Schlossberg, recounting her diagnosis with aggressive acute myeloid leukemia and her search for meaning, hope, and memory.
https://ascopost.com/issues/january-25-2026/a-battle-with-my-blood/
24 days ago
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🆕 The January 2026 issue of The ASCO Post features: highlights from ASH 2025, SABCS 2025, and GI 2026; and an essay written by Tatiana Schlossberg about her battle with AML reprinted following her death. Don’t miss this issue 👉
https://ascopost.com/issues/january-25-2026/
27 days ago
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📢 The FDA has issued a draft guidance for the use of minimal residual disease and complete response as endpoints in multiple myeloma clinical trials to support accelerated approval.
https://ow.ly/Q5bc50Y1n9K
28 days ago
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⚖️💊 FDA & EMA set global principles for good, responsible AI use in drug development. New guidance outlines 🔟 best practices to ensure AI tools support safe, ethical, and effective drug innovation. Read the full list of principles here 👉
https://ow.ly/C9Ka50Y0BC0
29 days ago
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📊American Cancer Society’s Cancer Stats, 2026: ⬆️ 5-yr survival rate for all cancers = 70% ⬆️ Significantly increased 5-yr survival rates: multiple myeloma, liver cancer, metastatic melanoma, regional lung cancer ⬇️ Mortality rate dropped by 34% through 2023
https://ow.ly/bukz50Y0gX9
30 days ago
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🥫 Study highlights possible links between select food preservatives and cancer risk: • Potassium sorbate, potassium nitrate, total acetates → ⬆️ overall & breast cancer risk • Sodium nitrite → ⬆️ prostate cancer risk 🔹Hasenböhler et al |
https://ow.ly/oJlT50XWc7r
about 1 month ago
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📊 Final data from phase III AGO-OVAR 2.29: No significant OS or PFS benefit with atezolizumab + bevacizumab + nonplatinum chemo in recurrent ovarian cancer, though a paclitaxel subgroup showed a favorable OS signal. 🔸 Philipp Harter, MD 🔗
https://ow.ly/PYjn50XVIWN
about 1 month ago
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🔬COMMIT trial shows triplet therapy (FOLFOX + bevacizumab + atezolizumab) significantly improved PFS vs atezolizumab alone in 1L dMMR/MSI-H mCRC (HR = 0.43) • 12-mo PFS: 67% vs 35% Caio Max Sao Pedro Rocha Lima, MD, MS 🔗
https://ow.ly/Mpgl50XT5Yw
about 1 month ago
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🍔A study found higher fast-food spending by block in Alabama was linked to more cases of early-onset colorectal cancer, while higher fruit & vegetable spending had a strong protective effect.🥦 🔹 Blake Buchalter, MPH, PhD 🔗
https://ow.ly/urH650XT29I
about 1 month ago
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🔮 The path forward isn’t AI instead of clinicians—but human+AI collaboration, according to Michael Sobolev, PhD et al. 🔹 Public trust, including for AI’s role in #cancer detection (currently ~15% of survey respondents), grows with experience. 🔗
https://ow.ly/EOYs50XS1A7
#cancer
about 1 month ago
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🔬Postoperative ctDNA testing may help personalize adjuvant therapy in patients with colon cancer—identifying those most likely to benefit from NSAIDs like celecoxib added to chemotherapy. 👨⚕️ George Q. Zhang, MD, MPH 🔗
https://ow.ly/XuPs50XS1p3
about 1 month ago
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📊Phase III inMIND trial: Adding tafasitamab to lenalidomide + rituximab significantly improved PFS in patients with relapsed/refractory Follicular Lymphoma (22.4 vs 13.9 months; HR = 0.43). 🔺Laurie H. Sehn, MD 🔗
https://ow.ly/PYBQ50XS1kF
about 1 month ago
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New meta-analysis shows that GLP-1 receptor agonists likely have little or no effect on obesity-related #cancer risk. Longer-term, cancer-specific studies still needed. 🔸Ko et al 🔗
https://ascopost.com/news/december-2025/study-explores-association-of-glp-1-ras-with-risk-of-obesity-related-cancers/
#cancer
about 1 month ago
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🩸 Potential new standard of care in newly diagnosed Multiple Myeloma ADVANCE trial from ASCO25: Adding daratumumab to KRd significantly improved MRD negativity vs KRd alone—without added toxicity in selected patients. 👨⚕️ C. Ola Landgren, MD, PhD 🔗
https://ow.ly/Cx2L50XNJ7S
about 2 months ago
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Happy New Year from The ASCO Post!
about 2 months ago
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🔬 TAP Highlight of 2025: Is this the end of cancer research as we know it? A proposed 15% cap on NIH indirect (F&A) costs threatens labs, clinical trials, and decades of progress in #CancerResearch—jeopardizing patients and innovation nationwide. 🔗
https://ow.ly/IGA850XNJ41
#CancerResearch—jeopardizing
about 2 months ago
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#YearInReview: In matched-related donor stem cell transplantation, cyclophosphamide + calcineurin inhibition significantly improved GVHD- & relapse-free survival vs standard therapy—without added toxicity. From #EHA25 🔸 David Curtis, MBBS, PhD 🔗
https://ow.ly/ZfQ450XNJ1R
about 2 months ago
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TAP Highlight of 2025 - Update in early HER2+ Breast Cancer: • Adjuvant: T-DXd beat T-DM1 in high-risk residual disease (HR = 0.47) • Neoadjuvant: T-DXd→THP improved pCR (67.3% vs 56.3%) • Signals for fewer CNS events (DB05) 🔗
https://ow.ly/3BCO50XNIRO
about 2 months ago
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🚨 ICYMI: NCCN early 2025 updates impacted practice across: • 🫙 Bladder: periop/sandwich IO + chemo; HER2-targeted options • 🫁 NSCLC/SCLC: more periop + consolidation IO; tarlatamab added • 🧬 mCRC: expanded IO + BRAF-targeted combos • 🩸 Myeloma: quadruplets gaining ground 🔗
https://ow.ly/1j7j50XNIzM
about 2 months ago
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Wishing you a wonderful holiday season!
about 2 months ago
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👉 Major takeaways from Treatment Advances in Malignant Hematology from NCCNhem25: • Immunotherapy-first strategies expanding • MRD driving treatment intensity • Biomarkers guiding frontline choices • Outpatient management of cellular therapies 🔗
https://ow.ly/bU3350XNIyw
about 2 months ago
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Deb Schrag, MD, MPH, has been chosen as the
American Society of Clinical Oncology
President for 2027–2028 The new Board of Directors and Nominating Committee Members have also been chosen. They will start their terms after the 2026 ASCO Annual Meeting. 🔗
https://ow.ly/8Ve050XNLay
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Deb Schrag, MD, MPH, FASCO, Elected 2027–2028 ASCO President
Dr. Schrag, a gastrointestinal medical oncologist, is the George J. Bosl Chair of the Department of Medicine at Memorial Sloan Kettering Cancer Center and Professor of Medicine at Weill Cornell Medica...
https://ow.ly/8Ve050XNLay
about 2 months ago
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🫂 When doctors are the family members, the words hit differently. Filipe Coutinho, MD, reflects on navigating cancer not as a clinician, but as a loved one, and how it reshaped his approach to care. ✍️ Filipe Coutinho, MD 🔗
https://ow.ly/iJBZ50XNhSz
about 2 months ago
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🏥
Dana-Farber Cancer Institute
's Neuro-Inclusive Oncology Care & Empowerment Program is rethinking #cancercare for patients with intellectual and developmental disabilities—prioritizing communication, sensory needs, and workforce training. ✍️ Melissa Levin, MSW, LICSW 🔗
https://ow.ly/yBzM50XNfIJ
#cancercare
about 2 months ago
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💡 For women with BRCA1/2 mutations facing surgical menopause: new prospective data suggest menopausal hormone therapy can be used without increasing #breastcancer risk. Joanne Kotsopoulos, PhD | #SABCS25 Learn more:
https://ow.ly/Pcs250XKAqj
#breastcancer
2 months ago
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Routine liquid biopsy screening for multiple cancers could cut late-stage cancer diagnoses nearly in half, per new modeling data of 14 cancer types. Earlier detection may significantly improve outcomes and reduce disease burden. 🔷 Chhatwal et al
https://ow.ly/IIKj50XA802
3 months ago
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Catch up on all of the highlights from ESMO Congress 2025! Dive into the latest breakthroughs in oncology in this #ESMO25-focused supplement from The ASCO Post including updates across immunotherapy, targeted treatments, and biomarkers. 🔗
https://ow.ly/JWtN50XA8rm
3 months ago
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🆕
American Cancer Society Cancer Action Network
study shows patients with cancer increasingly turn to crowdfunding for expenses. Only 11.5% of campaigns meet their goals, revealing major gaps in affordability and financial assistance #CostsofCare 🔸Zhiyuan Zheng, PhD 🔗
https://ow.ly/GUXl50XA883
3 months ago
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The November 25 issue of The ASCO Post features insights from ESMO 2025, ASTRO 2025, NCCNhem 2025; perspectives on the AI era changing health care, cancer survivor concerns of health care costs, and MORE. Read the full issue 👉
https://ascopost.com/issues/november-25-2025/
3 months ago
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🔬New CAPS analysis: Mild dilation of the main pancreatic duct is an independent risk factor for progression to pancreatic cancer in high-risk individuals. Risk reached 16% at 5 yrs and 26% at 10 yrs. ✍️ Marcia Irene Canto, MD, MHS 🔗
https://ow.ly/RnRA50XukBo
3 months ago
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🆕 DESTINY-Breast09 data in HER2+ mBC: • 44% reduced risk of progression/death • PFS: 40.7 mo • ORR: 85% T-DXd + pertuzumab may redefine first-line treatment, per
Sara Tolaney
et al 🔗
https://ow.ly/qu8q50XtBp7
3 months ago
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BART trial ASTRO25: Adjuvant Radiation Therapy after cystectomy reduced locoregional recurrence in pts w/ high-risk muscle-invasive Bladder Cancer Modern IMRT to the pelvis safe after surgery—supports IO integration in trials 🔷 Presenter Vedang Murthy, MD 🔗
https://ow.ly/Qexr50XrI7o
3 months ago
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The NCCN's Clinical Practice Guidelines in Oncology to be integrated into
@openevidence.bsky.social
's medical AI platform so clinicians can access trusted, evidence-based cancer care recommendations for decision-making support via natural language search. ➡️
https://ow.ly/QqaK50Xr3w4
3 months ago
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Pembrolizumab + weekly paclitaxel ± bevacizumab in pts with platinum-resistant ovarian cancer led to improved PFS, OS in overall, PD-L1 CPS ≥ 1 populations ovariancancer 🗣️From ESMO25 👩⚕️Presenter Nicoletta Colombo, MD, PhD; Discussant
https://ow.ly/FgHC50XqFJc
3 months ago
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The November 10 issue of The ASCO Post features insights from ESMO, ASTRO, and SOHO meetings; a Special Report on disaster impacts on patients & staff; perspectives on alcohol-associated cancer risks, and climate change & cancer development. Read full issue here:
ascopost.com/issues/novem...
3 months ago
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Zenocutuzumab-zbco led to responses in 37% of patients in a small cohort of patients with NRG1+ cholangiocarcinoma 🔹Clinical benefit rate 58%, median PFS of 9.2 months 🔹Presented at
#Targets25
by Alison Schram, MD of
@mskcancercenter.bsky.social
ascopost.com/news/october...
3 months ago
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A conversation with Ravi B. Parikh, MD, MPP, highlights how he has helped increase access to palliative care by integrating an algorithm into EHR to identify patients with cancer who could benefit Palliative care visits increased: 44% vs 8% in control group
ascopost.com/issues/octob...
3 months ago
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Living a Full Life: The ASCO Post spotlights the career of third-generation clinician Neelima Denduluri, MD, in conversation with
@jameabraham.bsky.social
. Dr. Denduluri has been a lifetime advocate for equity in medicine, breast cancer oncologist, ASCO mentor, & more.
ascopost.com/issues/octob...
3 months ago
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“Cancer is probably the most vulnerable field for fraudulent research” -Reese A.K. Richardson, PhD, of
@kelloggschoolnu.bsky.social
Richardson et al reported the amount of fraudulent scientific papers is doubling every 1.5 years due to paper mills, etc.
ascopost.com/news/october...
4 months ago
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President Joe Biden has completed his radiation therapy course for prostate cancer and rang a ceremonial bell to commemorate the milestone
ascopost.com/news/october...
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President Biden Completes Radiation Therapy Course
President Joe Biden has completed his course of radiation therapy for prostate cancer, which he recently marked by ringing the ceremonial bell alongside his radiation oncology care team.
https://ascopost.com/news/october-2025/president-biden-completes-radiation-therapy-course/
4 months ago
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