How great is the HPV vaccine? It can even ⬇️ the risk of cervical cancer when given after precancerous cells are found. I wonder why RFK Jr isn't talking about this study.🤔 www.thelancet.com/journals/lan...

Excited to share our preprint using time-resolved small-angle X-ray diffraction to study myosin motor conformations during isometric twitch and tetanus contractions in the slow-twitch rat soleus skeletal muscle #myoblue

We are looking for an enthusiastic MD or PhD to work on a postdoc project on the molecular mechanisms underlying human hibernating myocardium and ischemic cardiomyopathy. If interested send me an email! #heart #cardiomyopathy #sarcomere

Excited to share the first paper from my PhD! We looked at what traits help Aneides salamanders excel at climbing using museum specimens, CT scans, SEM, and more! No claws or toe pads, so how do they do it? In short, with long limbs, big feet and grippy toes! 🦎🧪 DM for PDF doi.org/10.1098/rspb...

This new #Methods article evaluates #freeze-drying to #RNAlater and three RNAlater-ICE-based protocols for #skeletal #muscle #biopsy tissue preservation for subsequent manual isolation of #fibers and other downstream applications. doi.org/10.14814/phy... #Physiology #MyoBlue

Calling all BPS member / interested muscle people!!! Sam Harris is spearheading a push towards make a new muscle subgroup at the Biophysical Society. *Signatures from active members are needed*, but anyone with an interest can sign. Please help the cause! www.change.org/p/establish-...

Congrats to Brent Scott from the Greenberg lab for this new paper on danicamtiv's mechanism of action. www.pnas.org/doi/10.1073/... Excited to see our FiberSim code being put to such good use. campbell-muscle-lab.github.io/FiberSim/

Can you really repair an engine while it's running? 👩🏽‍🔧 The heart can. 💪🏼🫀 Our latest @faseborg.bsky.social paper shows how the protein 'CapZ' helps heart muscle to keep running during exercise. ⛹🏼‍♀️🏊‍♂️ #Exercise #Heart #Muscle #BasicScience #Cardiology faseb.onlinelibrary.wiley.com/doi/10.1096/...

Global study: 2.08M people, 133 cohorts, 39 countries, 6 continents. 5 risk factors influence 50% of lifetime cardiovascular disease risk. PMID:40162648, N Engl J Med 2025, @NEJM https://doi.org/10.1056/NEJMoa2415879 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

This may be a bit strongly worded. Some people took initiative to write grants even when in a secure post doc. Some wrote grants that were tailored-made to be impactful/career boosting. IMHO, no problem with career strategy in an ultra competitive funding landscape. Wayyy more deserve than spots.

Yes! NIAMS and NHLBI as well!

Y’all!!! Our comparative anatomy textbook is out!!! Free, open access, and just in time for the fall semester!

"The successful candidate will have expertise in area(s) related to cardiovascular physiology, metabolic regulation and dysregulation, and/or hormonal mechanisms that maintain homeostasis, with a focus on aging."

All scientists need to be doing more of this and posting on all types of social media platforms (not just on the echo chamber communities). We must get better at communicating our science in a fun and effective way to a broad audience or tax payers/ voters.

Day of Action planned for July 21 to protect science protectscienceandinnovation.org

NIH moves towards alternatives to animal models, in line with the shift in the EU. This is not bad policy in principal but not yet always feasible on technical grounds. It's important to continue searching for "muscles in a dish" that are of quality for Xray diffraction. Who wants to collab?

nothing would make me happier than US science returning to the amazing and transformational legacy of success and dominance but if that's not possible, we need other places with the vision to take over as the pacesetter humanity's long term success demands no less

I was delighted to accept the King Charles III Coronation Medal for my lab's research & advocacy for women's heart health.🫀💃🏻 We appreciate the support of IMPART at @dalhousie.bsky.social & @womensresearch.bsky.social, & were grateful to be nominated by the Heart & Stroke Foundation of Canada.

Damien M. Callahan presents this #TranslationalPerspective on the work of Laitila et al. linking altered structure and post-translational modification of Troponin T to dystonia in nemaline myopathies💭 ✍️ 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

I am honored to announce that I was awarded the Du Bois-Reymond Prize of the German Physiological Society! “The German Physiological Society recognizes an outstanding and independent scientific work in a current field of physiology.”

At NSLS II, @brookhavenlab.bsky.social for another big muscle Xray research run. The science gods are telling me that this run will be 💯

🚨 Editor's Choice! 🚨 Research from University of Arizona shows L348P point mutation in cardiac myosin binding protein-C alters transient responses to stretch, slows cardiac relaxation & is embryonic lethal in homozygous CRISPR gene-edited mice Read: doi.org/10.1016/j.yj...

US Judge reinstated 848 NIH grants illegally canceled by th admin. The ruling, below, lays out all the grants. Read through them. See all the good that is being put back in place and then double your efforts to resist the destruction of the US science enterprise. acrobat.adobe.com/id/urn:aaid:...

Such a long-game push to discredit the best and brightest in the medical community. Only way authoritarian rule can form is to silence the expert class-I get it is part of your plan. But why not then go all in? No more doctor visits. No more medicine. Just thoughts and prayers for your whole family?

My latest for American Scientist Magazine helps give scientists the tools to fight back against politicized charges that our research is silly or pointless- tools that will work whether you’re asked “why are we funding this” from your asshole uncle at Thanksgiving or an asshole US Senator. 🧪🌎

Aurora Scientific is #hiring a Life Science Product Consultant. This position is dedicated to building and maintaining a lasting relationship with our customers by conducting sales and post-sales support activities. Apply now! ca.indeed.com/viewjob?jk=6...

Never forget that there are 400,000 scientists in the US of all career levels what are clawing our research funding back. This is a small win, and they will appeal. But every W is meaningful. It was also heartening to hear key senate Republicans reject Trump's proposed cuts to science funding.

Every US science lab should listen into this. Lab groups should hold meetings to watch together. This meeting is a very pivotal one for future NIH funding.

My fellow USA scientists. --> I see you working hard while dealing with the most uncertain research landscape in 80 years. --> Somehow, awesome research keeps being produced because this is what we do. We are some of the best in the world at it. Don't be shy to remind congress about it.

Innovators, Europe is calling: launch, expand, and lead here 🧪 The EU Startup & Scaleup Strategy aims to make Europe a top hub for tech companies by attracting talent, boosting innovation, and helping startups overcome growth challenges across the EU: europa.eu/!68QKr8 #philsci #SciComm

#American scientists. Your non-stem neighbors need to understand the debilitating effects of a budget cut like this. And your senators need to hear from you! This is the worst time in history for us to stay out of the ring.

📢🚨New paper alert! Another monster paper from an awesome group of researchers focused on changes to sarcomeric proteins with cardiomyopathies. Accelerated Muscle Biotechnologies was happy to play a small role in this important work. 👨‍🔬👩‍🔬🔬♥️💯 www.ahajournals.org/doi/10.1161/...

Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF

GDF8 and activin A blockade protects against GLP-1-induced muscle loss while enhancing fat loss in obese male mice and non-human primates www.nature.com/articles/s41...

[🚨New paper alert!] If you store muscle tissue in glycerol-mixed solution for long-term preservation, check out our new paper published in @jgp.org. Glycerol storage significantly elevates passive stiffness of muscle fibers in a titin-specific manner! More details are: rupress.org/jgp/article/...

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social www.science.org/doi/epdf/10....

EU augments opportunities for scientists around the world to launch or re-launch their careers in Europe.

👩‍🔬👨‍🔬💪💯Glad to play a small part in this big study! Congrats Jenni laitila, @OchDr and all authors! Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility - Laitila - The Journal of Physiology physoc.onlinelibrary.wiley.com/doi/10.1113/...

Twitter’s dominance ‘over’ as Bluesky becomes new hub for research. Data indicates more scholars turning to alternative social media site to post about their work after Elon Musk’s Twitter takeover www.timeshighereducation.com/news/xs-domi...

We’re sounding the alarm for science. Science is not a switch that can be flipped on or off. If we do not act now to alter our current trajectory it will undermine our prosperity, our democracy, and our children’s futures for decades to come. You need science. Science needs you. SaveScienceNow.org

Super cool new postdoctoral fellowship opportunity at MIT via the HEALS initiative. Biswas Fellows receive *4 years* of funding to pursue independent research with *any* MIT faculty member! Please share widely with the trainees in your life! heals.mit.edu/biswas-fello...

Our new very collaborative paper showing that muscle myosin has a reduced energy demand in diabetes. Big impact on weight control in our mind!!! Thank you to everyone involved and funders @lundbeckfonden.bsky.social @novo-nordisk.bsky.social @ucph.bsky.social @myoblue.bsky.social #diabetes

🚨📢It was great to write a commentary about the great science conducted by @cameronhill13.bsky.social. Time-resolved function-molecular structure of intact muscle (ex vivo)! Popping the hood of muscle motors using time-resolved, small-angle X-ray diffraction | PNAS www.pnas.org/doi/10.1073/...

⛔ NIH ended ALL of my grants mid-project, given LGBTQ health focus 🏳️‍🌈 ⚖️ So what am I doing? Suing RFK, Jr. As one team member shared in this story👇: "The threats to our work don’t just make me fear for my career — they make me fear for my safety.“ #SaveDemocracy #SupportScience #PublicHealth

I had a wonderful weekend at the CheffTreff summit in Hamburg. 5K future and current entrepreneurs attended. I was happy for the invite to provide some tips we learned during the development of our #DeepTech #BioTech, @ambiotech.us at the "Lab Bench to Market" stage. Germany is in good hands!

Scientists go where science can flourish. New things on the way for @ambiotech.us in Hamburg.

I have been invited (!) to tell my story about @ambiotech.us at the CHEFTREFF summit in Hamburg on Saturday, where 5K Startup / Biotech entrepreneurs and stakeholders come and mingle. 💪♥️🔬 Title: Selling deep-tech services to a niche market: A few things I was right and wrong about from the start.

ONE hour to the closest approach of Lucy with #asteroid (52246) Donaldjohanson [DJ]. ↔️ current distance to DJ: 48 thousand km ☀️ current phase angle: 13.41° 🪨 estimated size of DJ on L'LORRI camera: 12-21 pixels ▶️ www.whereIsLucy.space

I recently returned from the BioCAT beamline (APS), working on my projects related to MyBP-C and titin, and Nic Engels / Devin Nissen collected some last pieces for their PhDs. Dylan Reichert had his first MyoSAXD experience! Funding from German Research Foundation (DFG) and NIH (keep funding!!).