#CarbonMonoxide has #antiischemic and #antiinflammatory effects. This study explores the potential of #CORMA1, a molecule that effects controlled CO release, to protect #kidneys from warm #ischemia and #reperfusion injury in rat and swine models. doi.org/10.14814/phy...

This new Case report presents a case of #melorheostosis, a rare sclerosing #bone #dysplasia for which the #pathophysiology is poorly understood, and discusses its clinical and potential translational significance. doi.org/10.14814/phy... #TranslationalPhysiology

New data on #mitochondria Aminoacyl-#tRNASynthetase, DARS2, reports secretion by #airway #epithelial cells in response to #TNFα, and a role in #paracrine signaling resulting in M1 #macrophage like phenotype in recipient THP1 cells. doi.org/10.14814/phy...

Deadline approaching! Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025! Including, but not limited to: Age-related Fibrosis Organ Fibrosis Fibrosis in Transplanted Organs More Info: physoc.onlinelibrary.wiley.com/hub/journal/...

Study of overnight deep inspiration patterns in #obstructive #sleep #apnea patients with or without #asthma provides insight into the potential role of deep inspirations in mitigating overnight narrowing in lower #airways and asthma–OSA interactions. doi.org/10.14814/phy... #Breathing #Respiratory

This systematic review examines evidence for #Sexdifferences in human #skeletal #muscle fiber types and the influences of #age, physical activity or muscle group. doi.org/10.14814/phy... MyoBlue #Exercise #Ageing #Physiology

📢 Launched today, the Global Climate and Health Summit Phase One report! It sets out the next steps to drive adaptation to protect lives today & the mitigation needed to secure health for generations to come. Read the full report ⬇️ www.physoc.org/policy/clima... #ClimateAction #GCHS2025

Planning for #APS2026? Stay ahead of the game! Check out key dates and deadlines so you don’t miss a thing: https://www.physiology.org/professional-development/meetings-events/american-physiology-summit/dates-and-deadlines?SSO=Y#APS2026?#WeArePhysiology 🧪 📷: istock

Read this physiological Case study which examined #energy balance in two recreational, #ultra-endurance #cyclists on plant-based diets during a 30-day cycle ride across Canada. doi.org/10.14814/phy... #ExerciseandDiet #Metabolism #Nutrition

Study of heart-focused #breathing and attitude breathing techniques on #heartrate variability in young healthy subjects reports improved #HRV parameters and #cardiorespiratory coherence, with significant differences between sexes and individuals with or without #anxiety.

What does the air we breathe have to do with your brain? Studies have been finding links between higher concentrations of certain pollutants and the prevalence of #dementia. Read more from The New York Times#dementia https://ow.ly/26s050XmrXV #ISpyPhysiology 🧪 📷: istock

“Clean air, safe environments, & just energy systems are treated as fundamental rights, not privileges” - Shweta Narayan shares her vision for a healthy planet in our latest blog. Find out more about Shweta's work & clean air initiatives. Read the Q&A ➡️ www.physoc.org/blog/clean-a... #ClimateAction

Study of #heartrate variability in two birth cohorts, in Finland or Norway, indicates altered #autonomic regulation in adults born preterm with very low birth weight, especially women, potentially contributing to higher #bloodpressure. doi.org/10.14814/phy... #Birth #Cardiovascular

#TRPC6 channels are implicated in pathogenesis of severe #nephrotic syndromes. This study of TRPC6 in normal physiological #podocyte functions reports roles in #MMP7-shedding of #nephrin ectodomains and #apoptosis. doi.org/10.14814/phy... #Renal #IonChannels

Retrospective cohort study on effects of #caffeine in persons starting #Sodium-glucose #cotransporter-2 inhibitors, indicates high caffeine consumption may reduce the early decline in estimated #glomerular #filtration rate with SGLT2i therapy. doi.org/10.14814/phy... #Heart #Kidney

This new invited Review discusses how food-related #gut or #endocrine signals and #microbial #metabolites are detected by vagal pathways in #Interoception mediated regulation of #feeding and #glucose #metabolism. doi.org/10.14814/phy...

📢 Our Conference Attendance Award closes in one week! Get support to attend the upcoming #HumanMovement2025. ⏰ The next round of applications closes on 31 October. Apply now ⬇️

After you've submitted your #APS2026 abstract, what comes next? Applying for awards! Many of them are abstract-based, so kill two birds with one stone: • Submit abstract by 12/3: https://ow.ly/SZhL50X9qjA • Apply for awards (deadlines vary): https://ow.ly/NaLn50X9qjy #ProfDev 🧪

#Nicotinamide #N-methyltransferase inhibition is shown to improve limb function in experimental #peripheral #artery disease in male mice. doi.org/10.14814/phy... #Ischemia #SkeletalMuscle

This methods-focused review article discusses the theoretical backgrounds of #algorithms used in open-circuit whole-room indirect #calorimetry, compares performance in #simulations, and proposes practical guidelines for the future.

Study of disuse-induced #muscle #atrophy in a mouse model reports on muscle-type specific alterations and #adiponectin pathway response, including increased plasma adiponectin #MyoBlue #Myofiber

New #Methods article surveys #photophysical and spectral properties of popular #pH-sensing green fluorescent proteins, #pHluorins, including a new member pHluorin4, providing insights to optimize applications in different systems. doi.org/10.14814/phy... #GFP #FluorescentProteins #CellPhysiology

This study uses continuous video-recorded transnasal #laryngoscopy and simultaneous #airway pressure measurement to quantify the airflow resistance at these sites during noninvasive #ventilation in healthy adults. doi.org/10.14814/phy... #Respiratory

This week we celebrate International Open Access Week 2025. This year’s theme is “Who owns our knowledge”? Find out more at www.openaccessweek.org @physoc.bsky.social @apspublications.bsky.social #Physiology #OAweek

Check out our Virtual Collections to catch up with recent publications under our Calls for Papers! physoc.onlinelibrary.wiley.com/topic/vi-cat... @physoc.bsky.social @apspublications.bsky.social #Physiology

This study identifies rare natural #sugars, (sweet, yet low calorie, poorly metabolized in the body and non-obesogenic), that induce #FGF21 production and suppress sugar appetite in mice. doi.org/10.14814/phy... #Obesity #Diet #Endocrine #Metabolism

Calling all researchers working in nutritional physiology. Submit your abstracts to showcase your research at our 2026 Dietary Manipulations meeting! 📆 8 – 9 April 2026 📍 Manchester Metropolitan University, UK Abstract submission closes on 30 November. Find out more ➡️ buff.ly/9wkQjVG

Help shape the future of #PhysiologyEducation. Join physiology educators at our 2026 Education Meeting! 📆 14 - 15 April 2026 📍 Newcastle University, UK Register now to save with early bird rates ⬇️ www.physoc.org/events/fit-f...

This December, explore motor behaviour, movement disorders & neurotech innovations at #HumanMovement2025. Plus, join the debate at our point-counterpoint workshop. 📅 16 - 17 Dec 📍 @kingscollegelondon.bsky.social 💡 Register now to save with our early bird rates 🔗 buff.ly/076wSdu

ICYMI, abstract submissions for #APS2026 are open. Let's celebrate science in Minneapolis next April! Submission deadline is 12/3. Learn more: https://ow.ly/owLx50X7boC#APS2026🧪

MRI investigation of #cardiovascular function and LV myocardial perfusion in patients with #sepsis and #septicshock, in initial recovery and 1-2 months later, shows that #myocardium #microvascular integrity is not affected in the short term. doi.org/10.14814/phy... #Infection #Cardiac

Monitoring of #extravascular fluids is clinically important in many critical #disease states. This proof-of-principle study examines a novel #wearable #bioimpedance device for non-invasive monitoring of fluid shifts during lower body negative pressure in healthy adults.

Study of individuals with #longCOVID for #vascular responses to prolonged sitting reports similar responses as for healthy controls, suggesting vascular #COVID sequelae do not result from increased sensitivity to #sedentary behaviour. doi.org/10.14814/phy... #BloodPressure #Cardiovascular

It's time! The #APS2026 abstract portal is open! Submit your best work through 12/3 and we'll see you in Minneapolis in April: https://ow.ly/EjFJ50X4p89#APS2026#WeArePhysiology 🧪

Congrats to new #NobelLaureates Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for their discoveries of peripheral immune tolerance and T reg cells. Read more: https://ow.ly/aiHn50X74mS #NobelPrize #Physiology

Comparison of #respiratory regulation and #lung volume in healthy young adults undertaking land-based or aquatic #cycling matched for oxygen uptake (VO2) indicates #exercise in an aquatic environment can be more effective for training the respiratory system doi.org/10.14814/phy...

Study of individuals with a permanent #pacemaker and preserved LV #systolic function reports right #ventricle pacing frequency and implantation >60 months to be independently associated with increased cellular and #mitochondria #oxidativestress in PBM cells doi.org/10.14814/phy...

Three months to go: Our Call for Papers on "Tissue Fibrosis Through the Life Course and in Transplanted Organs" will end on 31 Dec. 2025! Find out more and submit your manuscript: physoc.onlinelibrary.wiley.com/hub/journal/... #Fibrosis #Transplantation #Physiology

#New data that cardiac timing effects on human information processing response speeds are modulated by #bloodpressure but not by #heartrate variability in healthy young adults. doi.org/10.14814/phy... #Interoception #Cognition #Physiology

Effects of short-term low #energy #availability in young adults at rest or exercising: this study identifies alterations in the #serum #metabolome as potential early #biomarkers of low energy availability. doi.org/10.14814/phy... #Exercise #Metabolism

Examination of effects of #ketone body supplementation on #exercise #metabolism in control or keto-adapted mice identifies #glycogen-thrifty metabolic adaptions favoring fat utilization during exercise in adapted mice.

#TissueFibrosis: Comprehensive comparative study of #lung #disease phenotypes between the single-dose and repetitive-dose #bleomycin-induced mouse models of #idiopathic #pulmonary #fibrosis highlights pre-clinical relevance of the repetitive BLEO-IPF model for IPF research.

#Sensory #electrical stimulation of the upper limb, below motor threshold, is shown to effect sex-related reductions in #spinal #excitability via reciprocal inhibition, providing implications for motor skill learning in #rehabilitation applications. doi.org/10.14814/phy... #Neurophysiology

Our latest Review article discusses the shared #pathophysiology mechanisms in chronic #kidney #disease and valvular #heart disease and evaluates current evidence on the #epidemiology, pathogenesis, and clinical impact of this disease association. doi.org/10.14814/phy... #Renal #Cardiac

Coming up at APS: • With Ditki: Using Interactive Drawing Tools to Teach Neuroanatomy and #Physiology 10/2 • With MediBeacon: Transdermal Assessment of GFR 10/7 • With Bayer: Neuroendocrine Basis of Vasomotor Symptoms 10/22 Learn more on our webinars page: ow.ly/WEWs50WuRYU#Physiology🧪

📢 Calling all post-doctoral researchers! Don't miss out on the opportunity to receive up to £2,500 to help you achieve your goals through our Unlocking Futures Fund. The deadline for applications is 30 September! ⏰ Apply now ⬇️

#PeerReview Week 2025: The Editors and staff of Physiological Reports Thank all our Peer-reviewers during 2025 for their commitment to #research quality and integrity and their support of the Journal. @physoc.bsky.social @apspublications.bsky.social #Physiology #PRW2025

🌍 PRW 2025 Events From webinars to in-person panels, this year’s calendar spans AI in peer review, research integrity, equity & more. 👉 Explore & register: peerreviewweek.net/events_all.p... ✨ Still time to submit your own event! #PeerReviewWeek #PRW2025 #PeerReview

#PeerReview Week celebrates the important role of peer review in advancing scholarly communications. The 2025 theme is “Rethinking Peer Review in the #AI Era”. Find out more at: peerreviewweek.net @physoc.bsky.social @apspublications.bsky.social @peerreviewweek.bsky.social

Investigation of physiological mechanisms that influence right-#ventricle and left-ventricle #kinetic #energy, computed from four-dimensional flow by #cardiovascular #MRI, reports increased contractility affects left ventricular kinetic energy in #pulmonary #hypertension. doi.org/10.14814/phy...