Congratulations to our undergraduate student, Maia Wang, for winning the first prize in the brain art competition at the Rutgers brain health institute annual symposium for her watercolour of an axon! Great job to all our lab members who submitted 5 fantastic pieces 🖼️

New York

Our PhD student’s, Jose’s, first poster presentation of his first author preprint on alpha-synuclein condensates!

The latest preprint from our lab! Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis www.biorxiv.org/content/10.1...

www.cell.com/cell/fulltex... Molecular grammars of predicted intrinsically disordered regions that span the human proteome

Success rates for Europe’s leading research grants are declining as a surge in applications far outweighs the funds available go.nature.com/479Sni6

Lab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!

Pleased to present the unboxing of our lab’s labubus! The green macaron named Lewy (after Lewy bodies) has officially decided to join our lab for its PhD thesis and is already learning how to write Python code 🔬 www.instagram.com/share/BAGYdC...

We celebrated the lab’s second anniversary! Proud of our accomplishments so far, including our paper in Cell Reports, several student awards, invited talks and good scores on NIH grants 🥳 Exciting new research is in progress and we will be ready to share it soon 🔬

Quote of the century from yesterday’s amazing Chan Zuckerberg bio hub Cell Biology at Scale symposium, which is now decorating our lab! 🐈

Lab photo July 2025!

Group imaging on our new confocal! 🔬👩‍🔬🧑‍🔬

Adding the first drop of oil to my lab’s new in-house confocal 🤩🔬👩‍🔬

Proud that 2 students in the lab recently received 4 fellowships and awards! Michael David Rothstein Endowed Scholarship; AΩA Carolyn L. Kuckein Student Research Fellowship; Cell Biology & Neuroscience undergraduate research excellence award; Henry Rutgers Scholar Award 🥳

A lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F #ASGCT2025 #MedSky @asgct.bsky.social

Our lab's first paper has been published! www.cell.com/cell-reports...

“We have evidence that this is fluid-driven, swarm-type seismicity that comes in pulses. This is not unheard of in other volcanic regions; however, this time it is evolving on top of active faults that complicate the expression of seismicity.” 🧪⚒️

Hi Seismo-Bluesky! I decided to test a pipeline with SeisBench, PyOcto, NonLinLoc, and HypoDD on the Santorini sequence. The level of activity (>4,500 events) is truly stunning! There are repeated bursts migrating backwards and forwards, spreading outwards from a narrow, almost linear channel.

Editors be like:

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that. www.biorxiv.org/content/10.1...

Is anyone else starting to think that its all about cillia? Researchers report PINK1 knock-out mice display cilia defects & reduced GDNF expression akin to LRRK2 mutant mice A convergent mechanism for #Parkinsons? www.pnas.org/doi/10.1073/...

Ten simple rules for developing good reading habits during graduate school and beyond journals.plos.org/ploscompbiol...

I started working on genetic therapies for Mendelian disease in 2000 - and in the subsequent 25 years have never seen a disease where the molecular aetiology has undergone as giant an "OH WOW" moment as this. www.cell.com/cell/fulltex...

This pretty much settles it: we're entering the era of low-cost, on-demand binders for everything Excited to see what people build now that "inject a llama with some junk and bleed it a month later" is no longer the cutting-edge tech www.nature.com/articles/s41...

Last western blot of 2024!

Some amazing accounts that post original cat content. Highly recommend them all. Will continue to add to this go.bsky.app/R7pZuYg

omg a student somehow accidentally wrote an email addressed to a faculty-wide NYU listserv and my inbox is now a master class on who understands the difference between a listserv and an email chain

New York City

www.nature.com/articles/s42... The latest collaborative publication from our lab!

San Diego

To all of us Early Career Scientist out there. Even the Nobel Prize Winner got his grant rejected today. I got my rejection today as well 💩💩

The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on? direct.mit.edu/qss/article/... A 🧵 1/n #AcademicSky #PhDchat #ScientificPublishing #SciPub

If you are a PhD student and like protein disorder (or want to learn more), Birthe Kragelund @bbkrage.bsky.social and Kristian Strømgaard are organizing a PhD course on How IDPs work 🧶🧬🧪 Note the cost if you are not at a Danish university. Details: phdcourses.ku.dk/DetailKursus...

#NIH #NINDS paylines are at 8% for fiscal 2025. Tough year is due to increased research costs and federal budget uncertainty for FY 2025. Director's message here. Worth reading. www.ninds.nih.gov/news-events/...

I noticed there wasn’t a starter pack for skeletal muscle scientists, so I made one as the muscle community continues to migrate here. Drop a comment if you’d like to be included! go.bsky.app/3hKK1WX

Following a suggestion from @benecal.bsky.social I will refer to these threads as "skeetorials" and will use this gif logo. Today's skeetorial is about the NIH Director's New Innovator Award with three different heroes (all in government). 1/n

GutBrainScience👏 #Connect & #Share #Science of a Healthy #Gut for a Happy #Brain go.bsky.app/8BwLnTX

Respectfully: go.bsky.app/NgdtfJy

The 1st rule of day science is to ask for each result, what is the negative control and what is the positive control, because we forget how easy it is to fool ourselves.

Our team at MGH is looking to hire a research technician to help us follow up our recent study exploring the death of neurons related to tau pathology. Anyone interested please reach out to me. #ADRD #Alzheimer's #Neurodegeneration #EndAlz www.cell.com/cell-reports...

I just got an email from a teacher that said “We are in need of a scientist that either studies frogs/other amphibians or the solar system”, and like, I understand that 3rd grade sometimes has you going from frogs one week to space the next, but this is still a very funny email.

I added just the bare min to get a list started. If you are into microscopes comment so I can add you. Looking to amplify new voices this time around go.bsky.app/8BCvm7W

Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras Complete with collective nouns I’ve been tracking these but now can’t keep up Hope it’s helpful 2/2 docs.google.com/spreadsheets...

Interested in lysosomes? Fully funded iCASE PhD studentship available between me at RVC, Emily Eden at UCL, and Andreas Dannhorn at AstraZeneca. Details below… www.findaphd.com/phds/project...