me sleeping seven hours vs. me sleeping six hours and 42 minutes

We have been holding vigils outside of the NIH for a year now. It's been a privilege to commune with such a kind, thoughtful and brilliant group of people. Together we push ourselves to fight for science, health and good governance. Happy anniversary, @nihvigils.bsky.social 🧁🎂🍰🥳🍾🍻🎉🎊

HAPPENING NOW: Tim Heidecker delivers an update on the future of InfoWars and takes calls from viewers including President Donald J. Trump.

Microsoft finally opened the vault: the original DOS 1.00 source code is on GitHub, offering a raw, unfiltered look at computing history.

Spike Lee at the Knicks game at MSG. #spikelee #popeleo #knicks #madisonsquaregarden

@hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits Stable, sustained support can transform your career: Senior Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

For all those still feeling the moon joy—Artemis II was brought to you by public schools and publicly funded science. Copy that! 👩‍🚀🚀💕 *All four astronauts went to public schools!

What's the physiological relevance?

🎯🎯

Throw the Editors of the NYT into the Gulf of America.

A few thoughts ahead of the President’s speech tonight.

The US needs to rebuild the train networks we used to have. No, we aren't the Netherlands, but this isn't about coast-to-coast trips. It's about connecting local neighborhoods, cities, and regions to help eliminate forced car dependency.

Thank you University of Oxford! 🐝🌎

Maggie Rogers, Joan Baez, and Tom Morello performing “The Times They Are A-Changin'”

Gotta love San Francisco folks showing up in Ocean Beach for No Kings! Awesome! 🔥

Omar: Just a couple of weeks ago, they told us that they blew up a drug trafficking camp in Ecuador and it turned out to be a dairy farm.

Just a guy out walking his turtles.

The Genome Technology Development Webinar Series. 👉 www.jax.org/GenomeTechDev26 👈 Three webinars featuring leading scientists discussing current capabilities, ongoing challenges, and future opportunities in genome technology innovation. Roundtable discussion following the presentations 🧪🧬💻👩‍🔬 #edusky

"This discovery demonstrates that sexual reproduction is indispensable for the long-term survival of mammalian species, the study said." 🧪

viking drive-in theater sign, darker sky, route 29, anderson, south carolina, 1988

A new mechanism for “RNA memory”! This time in Planaria! (Here's a video of a Planarian with mulitple heads, one of the heritable phenotypes we studied). This work summarizes >10 years of research and is an amazing collaboration with the labs of Jochen Rink and Omri Wurtzel labs. Read thrad below👇

A tomahawk missile costs the taxpayers the same amount of money as one five-year major NIH research grant. Remember that every time they tell us one of those missed the target, blew up paintings of enemy aircraft or tanks, or was the fifth and unnecessary hit on the same target.

Bazookasaurus xkcd.com/3216/

Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations. www.nature.com/articles/s41...

XPG's interaction with TFIIH's p62 & XPD through its spacer region is key for completing UV and chemo-induced DNA repair. Essential NER insight! PMID:41641700, Nucleic Acids Res 2026, @NAR_Open https://doi.org/10.1093/nar/gkag078 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Remembering Barbara McClintock on International Women's Day! She discovered that genes aren't static, they can actually "jump" around on a chromosome. Her discovery of transposons ("jumping genes") fundamentally changed how we understand evolution and the complexity of DNA! 🧬🌽 #WomenInScience

So much online conservatism these days is just "I miss being a kid"

Re-upping this post from a year ago. To invest in basic research is to invest in a better future for everyone. You know, everyone deserves a better future, not just billionaires or whoever owns stocks of AI companies.

“Academics tend to have this way of interacting with people that works really well when there is mutual good faith,” Aaronson says. “But it breaks down when that doesn’t exist. And I think a lot of academics were just not prepared to deal with someone like him.” www.science.org/content/arti...

My awesome colleague, @yarimura.bsky.social, is recruiting a postdoc to start at the end of 2026 or early 2027! His lab uses cryo-EM to uncover structural basis of key chromatin events using native complexes isolated from human cells or Xenopus egg extracts! careers-fhcrc.icims.com/jobs/30706/p...

Where do we draw the line in AI use for manuscript writing? 🧪 socopen.org/2026/02/22/w...

“In 1 of the simulations, 8x out of 10 (84%), the platform sent a suffocating woman to a future appt she would not live to see… Meanwhile, 64.8% of completely safe individuals were told to seek immediate medical care.” “40 million+ people reportedly ask ChatGPT for health-related advice every day”🧪

🧪 Please check out my new article titled- The Constructor Theory of Life- Why Intelligent Design is wrong and how life builds itself. It's on Medium, access using the link below: medium.com/science-spec... #science #philsky #philosophy #biology

Complex Peaks #Chemsky #ChemChat 🧪

“The researchers caught a twinkling surrounding the tips of leaves at ultraviolet (UV) wavelengths. They hope the work will shed light on how thunderstorms electrify the landscape and produce lightning.” #scicomm www.science.org/content/arti... 🧪

I wonder if there could have been hybrid sterility for XX due to disordered meiosis as well or instead? Pretty common in hybrids. In Evolution, a lot of stuff gets thrown at the wall and the diversity we detect is what happens to stick. 🧪

Below is the response to my question. The funny part of his response is that my research needed a control arm. My study actually did have a control arm (about 80% of the sample never reported discrimination). So the answer itself makes me even more confused.

This week's cover @thelancet.com

The Conference of Catholic Bishops is... not playing around in this brief. www.supremecourt.gov/DocketPDF/25...

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs

Just published: chemotactic sperm cells become phototactic 💡- by loading photo-activatable second messengers. This allows to "reverse-engineer" chemotactic signaling dynamics and expose cells to signals they would never see in the wild. Honoured to be part of this collaboration with the Kaupp lab.

We made FLIP2, a protein fitness benchmark spanning seven new datasets, including enzymes, protein-protein interactions, and light-sensitive proteins, as well as splits that measure generalization relevant to real-world protein engineering campaigns.

Eliminating the Impossible xkcd.com/3210/

“Open research is about more than the tightening of analytical and methodological standards. The movement also invites us to reconsider how, and by whom, knowledge is created, shared and evaluated” By @maddipow.bsky.social, @drcpennington.bsky.social, & @flavioazevedo.bsky.social #MetaSci #OpenSci

dammit Snake knock that off