Bugs delivering drugs: Listeria monocytogenes-mediated cytotoxin delivery enhances anti-tumor activity in colorectal cancer

#NewResearch Plasmodium falciparum proteins were engineered to create a nanoparticle vaccine platform capable of displaying multiple antigens at 48 sites #MicroSky #Malaria 🦠🦟💉 www.nature.com/articles/s41...

A big thanks to all the authors, reviewers, and readers of Nature Microbiology for their love and support throughout the year. We are on a break & will be back on Jan 2nd, in what will be a very special year for us! In the meantime, enjoy a collage made by @francoismayer.bsky.social #MicroSky 🦠

Yes, please! 😄

As the year ends, we decided to select our favorite papers of 2025 Turns out, it is impossible as we love them all! So, we picked 'some' that exhibit the range of microbiology highlighted through the columns of Nature Microbiology. Here is a glimpse into #EditorPicks of 2025 #MicroSky 🦠

One of the things I love about my job is the range of cool papers I get to read and researchers I get to work with to highlight the most interesting microbiological advances This thread is just a preview of the diversity of microbiology that came out in @natmicrobiol.nature.com in 2025 #MicroSky 🦠

People emailing to say that they sent you a message on Teams. Modern life is rubbish.

So many AI-written letters coming in... Are the machines feeling the pre-holiday crunch to submit as well? 🤖🎄

Franziska Faber and I are recruiting shared postdocs, PhD students to work on Fusobacterium & new BGCs. www.helmholtz-hiri.de/fileadmin/HI...

Two interesting papers, two different contexts, but both reminded me of the super cool recent article in @natmicrobiol.nature.com by @erikbakkeren.bsky.social that goes about setting general rules for ecological success in microbial communities. #MicroSky #MicrobiomeSky Links in the reply

Great viewpoint article by @kevinsblake.bsky.social & Gautam Dantas "we must rethink the brute force approaches that attempt (futilely) to fight resistance (...). Instead, we should pursue complementary strategies that mitigate selection of antibiotic resistance" 🦠 revive.gardp.org/ecological-s...

Looking for someone interested to apply for a postdoc grant with me on reindeer microbiomes. 🦌🦠🧬 Please email for details.

Excited to share our new @natecoevo.nature.com paper. We identified microbes found across nearly all ruminants that act as the functional backbone of both the rumen ecosystem and the host, with major implications for food security and climate change mitigation. (1/8) www.nature.com/articles/s41...

#Resource HRGM2 - a catalogue of 155,211 high-quality metagenome-assembled genomes spanning 41 countries that allows improved genome-scale metabolic modelling and functional characterization of human gut microbes. #MicroSky #MicrobiomeSky 🦠💻 www.nature.com/articles/s41...

#Editorial In the last editorial of the year, we talk about STREAMS - A new community-led checklist provides reporting guidelines for microbiome research across environments. #MicroSky #MicrobiomeSky 🦠 www.nature.com/articles/s41...

#ConsensusStatement A new Consensus Statement presents the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines. #MicroSky #MicrobiomeSky 🦠 www.nature.com/articles/s41...

#NewResearch Systematic analyses and machine learning coupled with in vitro and in vivo validation link gut microbiome-mediated transformation of dietary phytonutrients to health outcomes #MicroSky #MicrobiomeSky 🦠🌱 www.nature.com/articles/s41...

How does the arms race between #bacterial defense systems and mobile genetic elements contribute to #microbiome community structure? Read below for an insightful exploration of this issue! It will not disappoint @plosbiology.org 🧪 #bacteria #immune #phage #ecology

A long manuscript full of jargon in small text size and no line spacing is the best way to kill an editor's enthusiasm.

We're at 735 registrants and counting! 🎉🦠 If you haven't registered yet, don't miss out on this exciting (free) symposium on gut microbial metabolites and their impacts on host health. Please share with your networks. 🔗👇 isbscience.org/events/2025-...

The findings of a study in Nature Medicine introduce microbial elements as a component of the brain tumor microenvironment and lay the foundation for future mechanistic and translational studies. go.nature.com/44bO314 #medsky #microbiome 🧪

#NewResearch A bile acid-bound structure of toxin TcdB revealed the mechanism of inhibition and guided the design of a synthetic bile acid that alleviated C. difficile infection in mice. #MicroSky 🦠💊 www.nature.com/articles/s41...

Really fun collaboration with Roman Melnyk from The Hospital for Sick Children Research Institute and Peter Dosa from University of Minnesota, making synthetic bile acids to be gut-restricted prevents C. difficile infection in a preclinical mouse model

My dog is realising how I feel on a cold rainy day.

#NewResearch A preclinical study finds that respiratory immunization with an antibiotic-treated bacterial vaccine is a highly effective approach for inducing tissue-resident memory T cells that protect against lung and nasal infection with Bordetella pertussis www.nature.com/articles/s41...

#NewResearch Streptococcus thermophilus phages circumvent host CRISPR defences via AcrIIIA2, which complexes with enolase, a highly abundant glycolysis enzyme, to block phage RNA binding #MicroSky #CRISPR 🦠 www.nature.com/articles/s41...

Hi everyone, a few years ago, we started a list of labs studying bacterial immunty for students, editors, conference organizers... (currently n=79). Update time ! Send me a message to 1) add your lab or others 2) Correct info docs.google.com/spreadsheets... #Phagesky #Microsky

New online! Gut virome dynamics: from commensal to critical player in health and disease

Having a PhD means you can find the word “unfortunately” in an email faster that the search function

Paper alert! Proud to share our latest publication @natmicrobiol.nature.com #mycosky

Last week I found myself surrounded by brilliant researchers and talking about their exciting research at #ESSMicrobiome @events.embl.org If you missed talking to me, just a reminder that The Clinical Microbiome collection is still open for submissions! www.nature.com/collections/...

So many cool presentations and so many new potential papers! If you want to discuss your future paper in Nature Microbiology, don't forget to catch me around! #EESMicrobiome #MicrobiomeSky

I will be at #EESMicrobiome hosted by @events.embl.org from tomorrow. Looking forward to meeting brilliant people and learning about their exciting research. If you catch me around, do talk to me about publishing in Nature Microbiology. #MicrobiomeSky #MicroSky

We are looking for a postdoc to study single-cell transcriptional heterogeneity in the human skin microbiome. We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated. Funded by a new grant from MIT-HEALS.

The multi-kingdom cancer microbiome. #Cancer #Microbiome @natmicrobiol.nature.com 🧬 www.nature.com/articles/s41...

Why do some manuscripts get a decision faster than the others? Here is a quick guide to help you bridge the gap and get a faster primary evaluation. #editorome #AcademicChatter #AcademicSky open.substack.com/pub/editorom...

Super cool Pseudomonas-Bacillus interaction paper in @natmicrobiol.nature.com from Yun Chen with @gabrieleberg.bsky.social Phenazines shape Gram+ abundance & influence Bacillus cell biology Phenazines contribute to microbiome dynamics by targeting topoisomerase IV www.nature.com/articles/s41...

Nature research paper: Commensal yeast promotes Salmonella Typhimurium virulence go.nature.com/4mTnRzG

Nature research paper: A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 go.nature.com/4mZHupC

I started a little weekend project because clearly reading and writing during the weekdays was not enough for me! 😄 Please take a look and share some feedback! editorome.substack.com #MicroSky #MicrobiomeSky 🦠

Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.

Savour the fine flavour of our September issue, featuring... 〰️Bacterial prions in phage defence 💊Antibiotics from archaea 🔺Spike complexes in Sabiá, Junin and Machupo viruses 🛡️Aggresomes and mRNA protection 🤝A call for early-career teams ...and more, here 👇 www.nature.com/nmicrobiol/v...

The September issue is now online and chocolate has made it to the cover! 🍫 #MicroSky

Microbiome of 🧀! I love these food microbiology papers! 😀 www.nature.com/articles/s41...

A Nature Outlook article reports on the preliminary evidence that microbiota-based treatments can be beneficial for people with mood disorders, such as depression and anxiety. But how these interventions work is not clear, and human trials are needed. #microbiome #medsky 🧪

A Perspective in Nature Reviews Gastroenterology & Hepatology explores the global evolution of inflammatory bowel disease over the next 20 years and proposes strategies for prevention and health-care innovation. go.nature.com/4fW7sYy #medsky 🧪

Skin metatranscriptomics reveals a landscape of variation in microbial activity and gene expression across the human body - @niranjantw.bsky.social @astar-gis.bsky.social go.nature.com/4fVg95j

The top 4 posts on my feed were all about machine learning helping discover new biology. It's a revolution for sure.

Did I just read the best abstract ever? 😁 www.biorxiv.org/content/10.1...

Haha! Nice 😄