New Research Measuring population immunity against influenza using individual antibody titres: a multicountry, retrospective observational study www.thelancet.com/journals/lan...

New Review Leptospirosis—clinical review and updates on therapeutics www.thelancet.com/journals/lan...

"Copilot evaluation activities are not designed to generate generalizable knowledge or evaluate clinical hypotheses. As such, these activities were reviewed by Microsoft’s Corporate, External and Legal [...] and determined not to constitute human subjects research". Is this the new ethical approval?

In a Brazilian self-controlled case series of 5055 hospitalizations for Guillain–Barré syndrome, laboratory-confirmed dengue was associated with an increased risk of Guillain–Barré syndrome occurring within 42 days. Learn more: nej.md/4cjXU8h

Being presented tomorrow afternoon at #ESCMIDGlobal2026 as part of the Lancet session (Hall A3-1): Characterisation of immune responses targeting highly pathogenic avian #influenza A(H5) viruses in health-care workers in the Netherlands www.thelancet.com/journals/lan...

Late-breaking papers from across Lancet journals on tomorrow, including short-course treatments for UTI, maribavir for CMV, avian flu, precision treatment for TB, and adjunctive betamethasone for mycoplasma. 20 April, 1:30pm, Hall A3-1 #ESCMIDGlobal2026

Short piece in The Lancet - best thing I've read this week. "Performative cruelty & unchecked abuses of power are defining political leadership, fracturing the cooperative values of global health..." then on to explain how such contempt influences behaviour & new norms. Depressing but insightful.

Robert Read from Journal of Infection describing AI in publishing as a tsunami of custard 😂 #ESCMIDGlobal2026

Good morning #ESCMIDGlobal2026 -- if you're up early come and join me and other editors in ICM 13b for a session on overcoming challenges in publishing.

"Nearly half (49.6%) of responses were problematic: 30% somewhat problematic and 19.6% highly problematic".

Just typed "I wish you the beast of luck with publication elsewhere". Someone needs a vacation after ESCMID 🙄

@nature.com is hiring an editor to join the Clinical, Translational, Genetics and Biotechnology team and handle genomic technology areas, including genome engineering, cancer genomics, synthetic biology, omics-based diagnosis and technologies springernature.wd3.myworkdayjobs.com/SpringerNatu...

👀 "If those cases become eligible for VICP compensation, the program would face roughly $32 billion in annual claims." I keep saying that the antivaxx movement is very much motivated by profit. Excellent editorial.

I welcome this. We shouldn't be relying on shortcuts. www.nature.com/articles/d41...

New research article Characterisation of immune responses targeting highly pathogenic avian #influenza A(H5) viruses in health-care workers in the Netherlands: an observational, cross-sectional analysis www.thelancet.com/journals/lan... #IDSky #ClinMicro #ViroSky #OpenAccess #OA

Why do some #mpox outbreaks mostly affect adults, spread through sexual contact, while others affect children and are spread through household contact? A new mathematical model might reveal the reason and offer insights on how to adapt our outbreak response: bit.ly/4cmxdQB

Is it appropriate to include your cat in your conference presentation? Asking for a friend.

A group 1 hemagglutinin stem vaccine elicits broad humoral responses against influenza in phase 1/2a study www.nature.com/articles/s41...

In a new blog post, Paul E. Sax, MD (@paulsaxmd.bsky.social), writes about at-home microbiome tests and how the same sample can have strikingly different results, depending on the companies doing the testing. Learn more: voices.nejm.org/doi/full/10....

As a data nerd, I love it that #ESCMIDGlobal2026 sends you stats of your reviewer activity. Also, phew, I've only been a smidgen harsher than other reviewers, statistically insignificant. Trying not to apply journal standards to conference abstracts.

'This phase 2 trial showed the noninferiority of the immune response to vYF, as compared with the licensed YF-VAX, measured by seroconversion at 28 days after vaccination (day 29) in healthy adults 18 to 60 years of age in the United States.' #YellowFever #Vaccine www.nejm.org/doi/full/10....

Excellent reporting by Health Policy Watch documenting the seeming mundane (and often obscure) but vitally important changes to the executive board of WHO, which holds critical decision-making power. Talk about shifting geopolitics. Bookmark this! healthpolicy-watch.news/exclusive-ch...

Please don't ask for a phone call with the editor if your paper gets desk-rejected. Unless you have something juicy to say that cannot go into an email.

Our April issue is now online: www.thelancet.com/journals/lan... Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #CRISPR #Bordetella #pertussis #microbiome #MicrobiotaTransplant #aspergillosis #BSI #AMR #IDSky #ClinMicro #OA

One week to go! Say hi to Senior Ed Saleha Hassan and me if you spot us at #ESCMIDGlobal2026. Apologies in advance if I don't remember your name or your paper 🫣

There's always preprints... VE against emergency visit 57% with LP.8.1 vaccine in US VA patients. www.medrxiv.org/content/10.6...

Important: mpox case definition is not specific and also picks up children with varicella, in particular now at what's hopefully the tail-end of the mpox outbreak in DRC. Diagnostics key.

More from the penicillin delabeling front, an international effectiveness-implementation trial: “Multidisciplinary adoption of inpatient penicillin DOC was safe & significantly improved penicillin prescribing and reduced use of WHO restricted antibiotics.” academic.oup.com/cid/advance-... #IDSky

On the one hand, I hate seeing the same people giving the same talk each year. On the other hand, I hate preparing a completely new talk each year. #ESCMIDGlobal2026

Thought this thread is totally up my street and there you go, link to a personal view published by us at the end 😂

New funding for CARB-X and GARDP

Like this opinion piece very much. At the same time wondering though whether post-infectious syndromes deserve their own specialty? But then, how would you go about creating a new medical specialty...

Horror short story: When the plumber says 'see you next time' upon finishing the job and leaving.

Perfect Easter egg, couple days late.

New Research Immunogenicity of high-dose recombinant influenza vaccine versus standard-dose egg-grown and cell-grown vaccines among frequently and infrequently vaccinated young adults in Singapore www.thelancet.com/journals/lan...

Watching old episodes of ER and sketching the cat (on request by my kids).

Hashtag dropped! As has the app, finally. So much good stuff in the programme, trying to figure out how I can be in three places at the same place. Maybe I should give this teleporting thing a try... #ESCMIDGlobal2026

Trying to figure out who this secret editor is, none of us have such good hair 😂 Hat tip to Chris Leonard from the excellent Scalene newsletter for the link.

New comment The case for routine patient review in long COVID research www.thelancet.com/journals/lan...

Picked this up at the airport the other day and gosh, I don't think I can continue reading. Rolling my eyes so hard they're about to pop out my head. No shade to the author, I just disagree with the underlying culture too much.

Motherhood derails women’s academic careers — these data reveal how and why www.nature.com/articles/d41... "...women have almost five times the amount of childcare responsibilities that men have." "...more pronounced among mothers who were trained in departments without women in senior positions"

Fancy a career in scientific publishing? We're looking for an Associate/Senior Editor with expertise in device engineering to join the Nature Research Cross-Journal Editorial Team. Can be based in Shanghai or Pune. Closing date: April 15th. springernature.wd3.myworkdayjobs.com/SpringerNatu...

NIHR Clinical Lectureship in Primary Care @lshtm.bsky.social Post is open to fully qualified GPs with a PhD and an academic track record. 4 Years of funding to develop your portfolio at one of the UKs leading Public Health and Primary Care research institutions. Apply by 13th April 2026.

Bluebell season in the UK has started early this year; very quick sketch, impatient children came along.

This is wild! (please excuse pun) Large, randomized study showing that Wolbachia‑based Aedes mosquito population suppression alone can significantly reduce dengue infections in a real‑world, dense urban setting! #dengue #IDSky #singapore @nejm.org #MedSky

New Research Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study www.thelancet.com/journals/lan...

Lots of great content this month! I particularly enjoyed a comment on mpox -- are we ready for wider circulation of clade Ib? [Spoiler alert, no, not really]: www.thelancet.com/journals/lan...

Maybe stop parading quacks in front of "busy parents"... Also, the real question is, is getting RSV safe for infants? Of course not. Monoclonals and maternal vaccines have gone through rigorous trials.

New Research Double-dose azithromycin mass drug administration, facial cleanliness, and fly control measures for trachoma control in Oromia, Ethiopia (Stronger SAFE): a cluster-randomised controlled trial www.thelancet.com/journals/lan...