Could we build a human from scratch? Join our expert panellists as they answer audience questions about lab grown organs, brain implants and synthetic DNA. Listen now on your favourite podcast platform: lnk.to/AQOSBioengin...

Don’t miss Recent advances in reproductive immunology at #BSI25! Wed 3 Dec, 11:00–12:45, Room 3A. Explore new insights into pregnancy, menstruation, endometriosis & cutting-edge immune research. 🔗 Full programme: https://bit.ly/4a5iBp1

Review @cp-immunity.bsky.social A host-centric view of the microbiota metabolome www.cell.com/immunity/ful...

An international research team led by the German Cancer Research Center (DKFZ) has developed a novel, explainable AI model that aims to make the diagnosis of #prostatecancer more transparent and less susceptible to error. @natcomms.nature.com t1p.de/losb0

Nature research paper: Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry go.nature.com/479jKdH

Our new, free exhibition featuring shortlisted entries from the Wellcome Photography Prize opens tomorrow. Stop by to experience stories of health, science and human experience captured in stunning photographs from around the world. www.crick.ac.uk/whats-on/exh...

Thank you Anna Baulies Domènech and Abcam for inviting me to talk about my work at Cambridge. 🔬 I'm honoured to have been selected as a guest speaker. #abcam #abscience #cambridge #science #research #immunology #metabolism #imaging #crick You can read my work here: www.nature.com/articles/s41...

NEW content online!

An immigration crackdown makes the United States less attractive. Where should you hold your next conference? https://go.nature.com/407qJ2w

New Article! High-spatial-resolution mass spectrometry imaging of biological tissues using a microfluidic probe

Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance

REVIEW | M van Hul, P Cani et al. (UC Louvain): This Review discusses the impact of the gut #microbiota on #cancer and on cancer therapy. 💊 🧫 FREE to read:

Long-read sequencing can reveal hidden cancer mutations, but existing tools often produce false positives. SAVANA is a machine learning algorithm trained on cancer genomes, built to make analysis faster and clinically reliable. @isidrolauscher.bsky.social www.ebi.ac.uk/about/news/r... #oncosky

Just one month left to visit #HelloBrain, our exhibition all about the marvellous and mysterious brain. The exhibition will open to the public for the last time on Friday 20 June. www.crick.ac.uk/whats-on/exh...

In a recent episode of @trialstribspod.bsky.social, Professor Kevin Harrington spoke with hosts @prof-nick-james.bsky.social and Dr @hoda-aty.bsky.social to discuss how #OncolyticViruses are used to infect and destroy cancer cells, while also triggering powerful immune responses.

As tighter immigration policies are announced today, scientists continue to stress the importance of attracting international talent. Our director Paul Nurse spoke to the Observer about how this affects science in the UK: observer.co.uk/news/politic...

Nature reports on how researchers are studying why mitochondria are moving between cells and whether the process can be harnessed to treat cancer and other diseases. 🧪

ICYMI:

Metabolism shapes life EMBL Barcelona & @mpi-cbg.de researchers reveal how glycolysis drives early embryonic cell decisions. The studies, published in Cell Stem Cell (@cp-cellstemcell.bsky.social), uncover the instructive potential of glycolysis. www.embl.org/news/science...

Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies

Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good https://go.nature.com/42nGQt6

Online now: Targeted tumor therapy with L-cyst(e)ine-addicted bacteria-nanodrug biohybrids

A saliva test, which analyses men's DNA, could be used in helping to identify those at greater risk of #ProstateCancer, according to a new study led by the ICR's Professor Ros Eeles. Full story ⬇️ www.icr.ac.uk/about-us/icr...

Exciting new research in Nature Communications shows that D-lactic acid inhibits the growth of both normal and precancerous cervical organoids, while L-lactic acid has no effect. Check out the full article here:

🌟 Exciting #PhD Opportunity! Join my lab in beautiful #Vienna. We are studying tumor-immune interactions in #metastasis using #singlecell and #spatial omics! ⏰ Apply by 04/25 bit.ly/3l7WMhs more infos 👉 winklerlab.org

We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology. www.nature.com/articles/s41...

NEW content online!

✨New issue! ✨ Check out the latest in #metabolism research from across all disciplines. Read about #Macrophages, #Tcells, #Circadian biology, the effects of #Diet on #Body and #Brain - and many more topics! www.nature.com/natmetab/vol...

NEWS&VIEWS | LM Nascentes Melo, F Cansiz & A Tasdogan (DKTK, DE) #AldolaseA inhibition in cancer cells turns #glycolysis into an ATP-consuming process. Imbalanced glycolysis could overcome the intrinsic metabolic plasticity of #cancer cells. https://bit.ly/41Al0SQ

New #ScienceImmunology research involving mice and human tissues demonstrates how different immune cell types modify expression of stimulator of interferon genes (STING) to support their normal development and function. scim.ag/4idx7wn

1/ New preprint! 🍳 @elihei.bsky.social and our team at @embl.org , @dkfz.bsky.social, and @mskcancercenter.bsky.social built #segger - a fast, accurate cell segmentation tool for spatial transcriptomics that assigns transcripts to their cell origins! doi.org/10.1101/2025...

In case you missed our story from earlier this week, you can read about the newly discovered potential link between giving blood and certain beneficial genetic changes in this BBC News article covering the topic. www.bbc.co.uk/news/article...

"CDK4 selective inhibition improves preclinical antitumor efficacy and safety" www.cell.com/cancer-cell/... #Pfizer Lars Anders @cp-cancercell.bsky.social

The EACR stands against threats to cancer research. Protecting scientific research is vital for progress and and the development of new treatments. Read our full statement in support of our friends and colleagues in the US: eacr.org/statement-on...

‘The good, the bad, and the ugly: Tissue somatic evolution in ageing and disease’ Last chance to get free tickets to our upcoming #MedicineAtTheCrick event, this Thursday 13 March. www.eventbrite.co.uk/e/medicine-a...

A multimodal imaging pipeline to decipher cell-specific metabolic functions and tissue microenvironment dynamics Thanks for the feature @crick.ac.uk www.crick.ac.uk/research/pub...

Nature research paper: Cooperative nutrient scavenging is an evolutionary advantage in cancer https://go.nature.com/3QwPhgb

Good Sunday, all. The papers on #cancermetabolism and #mitochondrialbiology in this weekly curated issue are remarkable. Check the papers here: biomed.news/bims-camemi/... @biomednews.bsky.social "There's no sincere path you can take in life without having your heart broken."-David Whyte

Nature research paper: Intrinsic electrical activity drives small-cell lung cancer progression https://go.nature.com/40Yyzvb

A multimodal imaging pipeline to decipher cell-specific metabolic functions and tissue microenvironment dynamics. Nanoscale secondary ion mass spectrometry can differentiate between isotopes derived from labeled metabolites at subcellular resolution. 🧪 @natprot.bsky.social

🥳 Our 8th most downloaded article in 2024: Exploiting temporal aspects of cancer immunotherapy by Lesterhuis et al. https://bit.ly/3Xs8l... #immunotherapy @natureportfolio.bsky.social #NRCtop10of2024

Happy to see my work featured this week in @natprot.bsky.social @natureportfolio.nature.com If you haven't checked it out yet - doi.org/10.1038/s415... rdcu.be/d7WGO #CanSky #ImmunoSky #OncSky #AcademicSky #Metabolism #Cancer #Immunology #Microscopy #Protocols

With the news that #ProstateCancer is now the most common cancer in England, there's been a lot of discussion about improving early diagnosis. The ICR is researching new ways to identify men earlier who are at the highest risk of the disease ⬇️

Our new imaging protocol in @natureportfolio.bsky.social provides a unique way to study metabolic interactions in the tumour microenvironment. #ImmunoSky Read it here - rdcu.be/d7WGO doi.org/10.1038/s415... Thanks to my collaborators: @kreuzaler.bsky.social @crick.ac.uk @cancergrand.bsky.social

Are you using #AI to analyse #Histopathology images? A team of ICR researchers have created a glossary to help AI developers understand tumour histopathology. They hope that this will speed up the development of AI algorithms for cancer research ⤵️ doi.org/10.1371/jour...

A new testing method developed by our scientists at the @icrlondon.bsky.social can accurately predict which people with inflammatory bowel disease (IBD) are most at risk of getting bowel cancer.   Read more here 👇 cruk.ink/40XvVpx