Vini John
@vjohn07.bsky.social
📤 68
📥 167
📝 5
Post-doc at Frey lab @ CHLA. Interested in studying mucosal immunity.
reposted by
Vini John
Mucosal Immunology
about 1 month ago
Time for the August episode of the
#MucosalMonday
MI Podcast featuring a discussion with
@michael-silverman.bsky.social
,
@marionbrunck.bsky.social
, and Agnes Garcias Lopez; Medical mystery from
@ashu-mangalam.bsky.social
; and MI research with
@kknoop.bsky.social
open.spotify.com/show/0Q4Ve1x...
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Timing Exposure to Microbes
https://open.spotify.com/show/0Q4Ve1xI0xB5UfyySypytn
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reposted by
Vini John
Mucosal Immunology
about 2 months ago
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling in this work from
@saraalonsomera.bsky.social
@edelblumlab.bsky.social
and colleagues:
www.mucosalimmunology.org/article/S193...
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reposted by
Vini John
The American Association of Immunologists
2 months ago
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗
ow.ly/rwMU50Wy3Mp
#AAIRESTORE
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reposted by
Vini John
California Institute for Regenerative Medicine (CIRM)
2 months ago
It’s great to hear about the various career paths in the
#RegenerativeMedicine
field—from R&D and lab work to policy and
#SciComms
. Thank you to our panelists for sharing their experiences and insights.
#CIRMTraineeConference
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reposted by
Vini John
γδ T cell Forum
2 months ago
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice
#gdTcells
@natcomms.nature.com
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Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice - Nature Communications
Sepsis-associated encephalopathy (SAE) is a severe and often fatal consequence of sepsis. Here authors show in a mouse model of sepsis that γδ T17 cells, migrating from the small intestine to the meni...
https://www.nature.com/articles/s41467-025-62181-3
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reposted by
Vini John
Eberl Lab 👨🏻🔬👩🏽💻🔬🧫
5 months ago
The perfect end to a great
#gammadeltatoronto
conference: our latest review has just been published in Advances in Immunology! "Modulation of humoral immunity by γδ T cells: A potential adjuvant strategy for vaccination" 👉🏼
authors.elsevier.com/a/1l8ltErwXf...
#gdTcells
@forum-gd.bsky.social
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reposted by
Vini John
Amy Engevik
5 months ago
Happy
#FluorescenceFriday
!
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reposted by
Vini John
Waggoner Lab
5 months ago
Secretory IgM regulates gut microbiota homeostasis and metabolism
@natmicrobiol.nature.com
www.nature.com/articles/s41...
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Secretory IgM regulates gut microbiota homeostasis and metabolism - Nature Microbiology
Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.
https://www.nature.com/articles/s41564-025-02013-8
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reposted by
Vini John
Eduardo Villablanca
5 months ago
We’re excited to share our recently published story “A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as modulators of mucosal healing” in
@mucosalimmunol.bsky.social
Fantastic work led by
@ramoralescastro.bsky.social
!
www.mucosalimmunology.org/article/S193...
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A zebrafish model of intestinal epithelial damage reveals macrophages and igfbp1a as major modulators of mucosal healing
The intestine is a semipermeable tissue responsible for the absorption of essential nutrients while limiting exposure to harmful environmental factors. To maintain these functions, the intestinal epit...
https://www.mucosalimmunology.org/article/S1933-0219%2825%2900042-X/fulltext
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Check out this paper on the role of ACC1 in γδT17 cells in vivo in a psoriatic mouse model
#gdtcells
add a skeleton here at some point
5 months ago
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reposted by
Vini John
Waggoner Lab
5 months ago
Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease
www.nature.com/articles/s41...
@natimmunol.bsky.social
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If you are at
#AAI25
in Hawaii and interested in learning about intestinal epithelial and IEL crosstalk. Please do stop by my poster # 1107 today from 10:30-11:45am. Session Title: MUC6P -Regulation of Mucosal Immunity.
@squeakyanimal.bsky.social
#Immunology2025
5 months ago
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reposted by
Vini John
Parse Biosciences
5 months ago
The Parse team is presenting one more scientific poster this morning at
@aai.org
! Meet us at board 1187 at 10:30 to learn about how Evercode technology as the only all-in-one solution for humanized transgenic mice.
www.parsebiosciences.com/aai-2025/
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reposted by
Vini John
Michal Caspi Tal, PhD
5 months ago
1/ My group is at
#IMMUNOLOGY2025
presenting our research. For those of you following along from home I want to share 1 min videos of each presenting their posters. @PaigeSHansen did an incredible job here presenting her about Lyme disease and gynepathologies.
add a skeleton here at some point
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reposted by
Vini John
The American Association of Immunologists
5 months ago
#ICYMI
scenes from
#IMMUNOLOGY2025™
from Saturday, May 3!
#AAI2025
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reposted by
Vini John
Marvic Carrillo Terrazas
5 months ago
Aloha!🌺 Super excited for another year at
#Immunology2025
representing the Chu Lab👩🏻🔬
@chulab.bsky.social
This time I’ll be sharing the induction of pro-inflammatory responses by B. fragilis isolated from an IBD patient👀 Want to hear all about it? Stop by poster
#1046☕️
#LatinaInSTEM
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reposted by
Vini John
Immunology Podcast
5 months ago
Can't make it to
#IMMUNOLOGY2025
? Brenda and Jason will be recording from Honolulu to keep you up to date!🎙️ Our first daily episode will be released on May 4. Stay tuned!
#AAI2025
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reposted by
Vini John
Prof. Akiko Iwasaki
5 months ago
Excited to participate in the 2025 annual American Association of Immunologists meeting in Honolulu 🏝️ Looking forward to seeing my colleagues and learning about the latest advances in immunology.
#AAI2025
and
#Immunology2025
@aai.org
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reposted by
Vini John
Waggoner Lab
6 months ago
ICOS+CD4 T cells define a high susceptibility to anti-PD-1 therapy-induced lung pathogenesis
@jci-insight.bsky.social
insight.jci.org/articles/vie...
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reposted by
Vini John
The American Association of Immunologists
6 months ago
Heading to
#IMMUNOLOGY2025™
? Want to maximize your experience? Join our webinar for insider tips on scientific highlights, networking in our new MHC collaboration zones, social events, and more. Register now and ask your questions live:
ow.ly/veEt50Vv9Iq
.
#Immunology
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reposted by
Vini John
Nature Microbiology
6 months ago
Out now! Live bacteria can translocate to other tissues via Colonic goblet cell-associated passages which may be beneficial to the host!
#MicroSky
#MicrobiomeSky
🦠
www.nature.com/articles/s41...
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Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice - Nature Microbiology
Colonic goblet cell-associated passages allow translocation of live bacteria to other organs in early life, potentially leading to beneficial impacts.
https://www.nature.com/articles/s41564-025-01965-1?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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reposted by
Vini John
American Physiological Society
6 months ago
#APS2025 starts in three weeks! We're excited to share some programming highlights, including our #NobelLaureate and prestigious award winners who are keynote speakers, and our game-changer sessions. Read more:
ow.ly/Re2950VtNTa
#APS2025
#NobelLaureate
#WeArePhysiology🧪
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Super proud of my former lab mate and friend. It’s been amazing to witness this journey from the very beginning to the grand finale hehehe. Thrilled to be a part of it-Congratulations, Sree! ☺️ 🎉🎉🎉
www.nature.com/articles/s41...
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Colonic goblet cell-associated antigen passages mediate physiologic and beneficial translocation of live gut bacteria in preweaning mice - Nature Microbiology
Colonic goblet cell-associated passages allow translocation of live bacteria to other organs in early life, potentially leading to beneficial impacts.
https://www.nature.com/articles/s41564-025-01965-1
6 months ago
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reposted by
Vini John
Edelblum Lab
7 months ago
📣 New preprint drop! In
#ScienceImmunology
, we found that regulatory
#CD39
γδ IELs are reduced in
#IBD
, now
@saraalonsomera.bsky.social
shows that gut
#microbiota
promote enhanced CD39 expression in γδ IELs through
#TCR
and IL-15 activation.
#gdTcells
#GIresearch
#Gastrosky
@sinaiimmuno.bsky.social
add a skeleton here at some point
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reposted by
Vini John
Edelblum Lab
7 months ago
If you read our
#ScienceImmunology
paper and want to know how the
#microbiota
induces
#CD39
to promote a
#gdTcell
#immunoregulatory
phenotype, check out our new
#preprint
!
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Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...
https://www.biorxiv.org/content/10.1101/2025.03.22.644616v1
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reposted by
Vini John
Waggoner Lab
7 months ago
Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling
@edelblumlab.bsky.social
doi.org/10.1101/2025...
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reposted by
Vini John
Society for Mucosal Immunology
7 months ago
It's here! Check out the latest Mucosal Immunology Podcast featuring Dr. Cecilia Johansson from Imperial College London, and solve the new Medical Mystery from Ashu Mangalam. 🩺✨ 🎧 Tune in now:
socmucimm.org/resources/mu...
#MucosalMonday
@mucosalimmunol.bsky.social
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reposted by
Vini John
Edelblum Lab
7 months ago
#Bluetorial
: In our latest paper on
#gdTcells
and
#IBD
in
#ScienceImmunology
we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n
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reposted by
Vini John
Waggoner Lab
7 months ago
Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis
www.science.org/doi/10.1126/...
@nbgolovchenko.bsky.social
@sciimmunology.bsky.social
@edelblumlab.bsky.social
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Very interesting study on gdT cells
add a skeleton here at some point
7 months ago
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reposted by
Vini John
The American Association of Immunologists
7 months ago
Registration is open for the 2025 AAI Immunology Courses! 🔬 Enhance your knowledge from introductory to advanced. ➡️ Introductory (UCLA): July 8-13. ➡️ Advanced (Boston): July 27-Aug 1. Learn from leading experts! Register now:
ow.ly/ACr850VkUm9
#Immunology
#AAIcourses
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