@msu-medicine.bsky.social will host Seminar by Dr Paul Macklin's titled "Reusable and Extensible Computational Models for Virtual Laboratories, NAMS, and Future Digital Twins"Tuesday (March 17) 2pm in #GrandRapids Research Center. #SpartansWill. @michiganstateu.bsky.social, @msuegr.bsky.social

So proud of @msu-medicine.bsky.social faculty Jenny Klomp! @MSUMD #AACRras26 #SpartansWill

Dieter Saur, Zachary Hauseman, James Duncan, and Jennifer Klomp discussed "Effector Signaling" in a plenary session at the AACR Special Conference on RAS Oncogenesis and Therapeutics. #AACRras26 @saurlab.bsky.social

@rephaleystevens.bsky.social @nazita.bsky.social @chazhong.bsky.social Please give this a boost!! Let's get people out at the rally!!!

"A man who suffered his first of many heart attacks at 37 gained five more extraordinarily productive decades," @chazhong.bsky.social writes. "This was nothing short of miraculous, but it wasn’t lucky — it is a testament to human ingenuity."

Spot on…for all cures - past, present & future -come from research. #SaveNIH

"Maintaining our current level of progress in biomedical research requires continued additional investment simply to keep pace." This Viewpoint explores how funding has changed at the US National Institutes of Health (NIH) over time. https://ja.ma/3RQPP11 #MedSky

Thank you to organizers of 1st Ferroptosis conference in US. We learned so much! Congrats to Brent Stockwell, who coined the term! Our work on novel mechansim of #ferroptosis regulation by GPCR & its therapeutic potential will add to this area! Stay tuned! #SpartansWill @msu-medicine.bsky.social

Honor to give psychiatry lecture on phenotypic approach to drug discovery at Pine Rest Christian Mental Health Services, 2nd largest of its kindl! We need to find paths for new therapies in psychiatry. Our patients & loved ones are waiting. Thank you, Dr. Nagy Youssef for hosting me. #SpartansWill

A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved

Meanwhile, exercise, low sodium diet, statins, BP meds, and vaccines go underutilized or out of reach of millions....

State interference: How not to do science. Lysenko convinced Stalin to reject genetics in favor of #Lamarkism, leading to disastrous effects on Soviet economy. USA's “Secret Sauce," is our Research Universities & Academic Freedom, now threatened by political interference. #StandUpForScience2025

This is a head scratcher. All I did was post that "without research, we're doomed." Or maybe mock Elon for mocking hard working Americans?

Years ago, using chemical genetics in zebrafish, I elucidated the role of #PI3K in vein specification. Just spoke to someone who has #VenousMalformation d/t somatic activating mutation in PI3K subunit. Learning how this knowledge is helping him made my day! #SpartansWill @zebrafishrock.bsky.social

What batshit crazy stuff are they saying?! This is like blaming Poland for Hitler & Stalin’s invasion in 1939! #StandWithUkraine

Come join an amazing department.

A bold move by MSU! "A more unified approach to medical education supports the creation of a critical mass of talented clinician scientists to enable high-impact research, attracting funding, & increasing institutional reputation.” #SpartansWill www.healthsciences.msu.edu/one-team-one...

WE'RE HIRING!! @msu-medicine.bsky.social is recruiting outstanding #CancerBiology scientists, especially those w/ expertise in #CancerImmunology, #CancerMicroenvironment, #TumorMetabolism, & #NutritionMicrobiome tumorigenesis links. #SpartansWill careers.msu.edu/jobs/assista...

Millions, maybe you also, are alive & well today because of research. Medicine without Reasearch is just Sorcery… #SaveNIH

Collaboration b/t our super star recruit @jennyklomp.bsky.social & @henryfordhealth.bsky.social colleague @hccvpdac.bsky.social will brighten the outlook for pancreatic cancer patients!! #SpartansWill @nullalleles.bsky.social @msu-medicine.bsky.social msutoday.msu.edu/news/2025/he...

Spent the first day at my new office in Doug Meijer Medical Innovations Building in Grand Rapids. Three of us from @msu-medicine.bsky.social are the very first occupants of this awesome space! Bit lonesome here, so we’re hiring! And is Detroit next? Stay tuned! #SpartansWill!

Hong lab is on a roll in 2025! Our latest paper showing GPR68 inhibition induces #ferroptosis & #radiosensitivity in diverse cancer cell types like lung & pancreatic cancer cells. Therapeutic synergy with radiation therapy. #SpartansWill rdcu.be/d8rGf

New grant ideas for 2025 NIH: "Genetic disorders: Accident or reason to blame your parents" "Fluoride, mind control drug or drug to control your mind" "Polio, was it really that bad?"

Cool visualization of ERK activation! @jennyklomp.bsky.social & @nullalleles.bsky.social

w/ pH-sensing probe, we visualize acidic microdomains in tissues of live whole animals, including extracellular spaces of myotome & w/i T-tubules, opening up cool questions regarding their role in health & disease. Link to paper 👇. #SpartansWill. @zebrafishrock.bsky.social @msu-medicine.bsky.social

Truly thankful to Will & his mother Emily who has glioblastoma, for visiting our lab at MSU & sharing their experience of living with GBM & wonderful care they received at @henryfordhealth.bsky.social We learned so much & are inspired by your courage. #SpartansWill @msu-medicine.bsky.social

Been nursing a nasty head cold. Whoever design these medicine packets deserve to be put in a special purgatory.

Blue birds huddling together for warmth

“Too much sitting hurts the heart, while ‘fart walk’ after meal protects the heart.” Did Confucius write this?

I’m honored to share that I will be a MSU Research Foundation Professor! Established w/ Cisplatin revenues, Foundation Professors are awarded to “exceptionally accomplished faculty members, with the aim of enhancing the stature of the institution in research and creative activity.” #SpartansWill

Happy birthday, Jesus, from San Francisco!

🔹MD-PhDs had a lower lifetime earning potential than MDs 🔹Inverse relationship between earning potential and research effort 🔹MD-PhDs in high-earning specialties tending to spend less time on research @jci-insight.bsky.social insight.jci.org/articles/vie...

Also, visited MSU St. Andrew’s campus in Midland to meet my chemistry collaborators. Did you know #Allegra was developed here? We’ll find a cure for brain cancer here. Stay tuned! #SpartansWill @msu-medicine.bsky.social #ferroptosis #Cisplatin2.0!

Wonderful visit to Michigan State University Midland campus. Such amazing work by dedicated staff & educators! They dserve a medal for their success in alleviating doctor shortages in rural Michigan! @msu-medicine.bsky.social #SpartansWill

Some Holiday cheer by @msu-medicine.bsky.social faculty Chuck Williams at MSU Speed Data Event! #SpartansWill @zebrafishrock.bsky.social

“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.” www.researchamerica.org/2023-oped-us...

"But many fear that the next administration will nonetheless weaken the N.I.H., divesting from critical research with long-lasting consequences for science, innovation and public health." @nytimes.com

Good to see @zebrafishrock.bsky.social on Bluesky!

This publication today on multimodal #AI to accurately and precisely predict an individual's heath trajectory, in this case #Parkinson's disease, is a frontrunner for many to come www.nature.com/articles/s41...

My comments to @tctmd.bsky.social about why I left that other social site for bluer skies 🦋. Also comments from @load-dependent.bsky.social @cardioobdoc.bsky.social @vietheartpa.bsky.social @jgrapsa.bsky.social #CardioSky www.tctmd.com/news/once-bu...

Great collaborative work spearheaded by M. Ardissino showing that, among those sustaining early-onset myocardial infarction, a CAD polygenic risk score was the strongest among assessed predictors of recurrent events www.ahajournals.org/doi/10.1161/... @ahajournals.bsky.social

Two very nice papers in cardiovascular genetics in two days. The first examines myocardial trabeculation: www.nature.com/articles/s44...

The second is a large-scale dilated cardiomyopathy GWAS: www.nature.com/articles/s41...

🚨🚨🚨 Our new review is out highlighting research priorities for SCAD, lead by Esther Kim, Daniela Crousillat, and Amy Sarma Spontaneous Coronary Artery Dissection: Current Knowledge, Research Gaps, and Innovative Research Initiatives: JACC Advances Expert Panel www.sciencedirect.com/science/arti...

Our preprint: Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart Multiomic atlas + human genetics = new cell types, genes, and pathways that influence heart development and disease www.medrxiv.org/content/10.1... Thread 👇

Our mini-review on proton-sensing GPCRs & oncogenesis is out. Highlights critical link b/t aerobic glycolysis, first described by Otto #Warburg, acidic tumor microenvironment & pro-oncogenic protection from #ferroptosis. #SpartansWill #Ogremorphin probiologists.com/Article/proton…

Biden Administration Takes Latest Step to Lower Prescription Drug Costs by Proposing Expanded Coverage of Anti-Obesity Medications for Americans with Medicare and Medicaid This is a win for our patients #obesity #CVPrev #CardioSky #CVprevSky 📎 www.whitehouse.gov/briefing-roo...