The "250" looks very bad?

As perceived in my timeline

Soft launching a new conspiracy theory that PG&E's outages have all secretly been on purpose, because their execs read too much Yudkowsky.

Elder rich horror

Mr. Worldwide? You mean Santa Claus?

Nice little Yuletide fire in the CVRI lobby today

Power is back!

TIL that 125k people out of 825k people is 2.2%, not the 15% that I mistakenly had believed. Thank you, PG&E.

Marked safe ✅ from even perceiving the earthquake.

We did a deep dive into aortic stenosis genetics, and took first steps to understand the genetics behind normal human variation in flow across the aortic valve.

Please also check out the excellent AS GWAS from @broadinstitute.org friends and colleagues @aeronsmall.bsky.social and @pnatarajanmd.bsky.social, published concurrently in Nature Genetics. Their work provides impressive insights into the genetic architecture of AS nature.com/articles/s41... 10/10

We’re excited to share our new Nature Genetics paper examining the genetic architecture of aortic valve function and aortic stenosis. We used deep learning of cardiac MRI and MTAG to study disease biology long before clinical diagnosis. nature.com/articles/s41... 1/10

argmaxxing

glad cow disease

It’s always nice to see the markets green and having a good time.

california is the america of america, you might even say

Fire near Dolores Park

Earthquake?

People who don’t create useful commit messages: why?

We explore a bunch of alternative models in the paper, but our main conclusion is that nearly all recessive genes have small (quantitative) effects in heterozygotes, and this is actually the main target of selection.

What goes on here?

New AWS outage explainer: your zone was unexpectedly deorbited.

Every single academic who has preprinted anything in the past year got this email from UChicago. I was so skeptical that I actually contacted the University of Chicago IRB, which indeed confirmed that they had (to paraphrase) approved spamming every academic.

SHapley Additive Reasoning Traces

Vote for me and you get: * Official 🇺🇸 font: Wingdings * Official 🇺🇸 programming language: Malbolge

Solipsistic Internet Theory >>> Dead Internet Theory

If you use AI chat agents, the single greatest productivity hack is to disable any “memory” features.

Yo CMMS uhh how can you tell

Very interesting to see an official comment (from ‘dang) about AI-generated content on HN: news.ycombinator.com/item?id=4610...

She’s reading / the discourse 🎶 She’s scrolling / her feed

Secondhand smoke is alive and well in Reno NV.

Bed, Bath, and the High Beyond

My problem? Oh it’s between chair and keyboard, you wouldn’t know it.

My hips don’t lie (they’re sore from sitting too much)

Low-volume machine learning subreddits are becoming a prime candidate for Dead Internet Theory.

Formulating annoying new ways to pronounce “Gaussian”

Me, when I’m yelling at the TV:

These tools (like Apple’s FaceID) work well for verification, but not identification. In other words, it is unlikely that some random person who grabs your phone will match. But if you were to centralize the lookup (identification), you’d match thousands of people. Hence OK for verification, not ID.

Chekov’s Gundam

Waymo in Wine Country is going to save lives: www.dmv.ca.gov/portal/vehic...

My best guess is that for every 1,500 Waymos you have on the street for a year, you save one additional human life.

Well I think the Waymo discourse has dried up. Time to start up some Zoox discourse.

INCREDIBLE CURVES

Late to work because a garbage truck driver pulled so close to my Waymo that it went into collision mode. 🫡

We are excited to announce EchoPrime is published in Nature. EchoPrime is the first echocardiography AI model capable of evaluating a full transthoracic echocardiogram study, identify the most relevant videos, and produce a comprehensive interpretation!

I need San Francisco to have its own satellites.