It's out! 🥳 In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET. 📝 Paper: www.nature.com/articles/s41... 🧵 Thread: bsky.app/profile/madi... #teamtomo #proteomics #AlphaFold

💡 ℹ️ Cette semaine, les Étincelles du Palais sont en mode pont. L'offre grand public (exposés, séances de Plané) courra du mercredi 13h jusqu'au dimanche 18h ; avec donc ouverture jeudi de l'ascension ainsi que vendredi 15. Réservez vos places ⤵️ billetterie-etincelles.palais-decouverte.fr?nopopin=1

Breaking news: Indiana University plant microbiologist Roger Innes has been locked out of his laboratory by the school in response to a request by one of his federal funders. The move comes after Innes complained about the government’s prosecution of Chinese postdocs. https://scim.ag/4tsDqRr

#RIP Pierre Chambon (1931-2026) via @alainberetz.bsky.social one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes

New paper with the @qubit-pharma.bsky.social team led by Narjes Ansari, just published @commschem.nature.com : "Dual-LAO for calculating fast and robust relative binding free energies of simple and complex transformations". #compchem #compchemsky #compbio www.nature.com/articles/s42...

Fabricated citations in the biomedical literature have increased 12-fold in two years, according to an audit of nearly 2.5 million papers published as a letter to The Lancet today.

Don’t reach for ChatGPT Images or Nano Banana as your first option when creating scientific images There are multiple free and open-source images, icons, and tools for creating scientific illustrations. #plantscience @stephenturner.us blog.stephenturner.us/p/free-open-...

After discovering a recent article about LLMs fabricating analyses from nonexistent data (arxiv.org/abs/2603.21687), I did an experiment with our new lab-sanctioned chatbot. Well, here’s the result (in case that’s not clear, I never actually uploaded any grades-intro-cs.xlsx file).

"Comme Jeanne d'Arc, rallumons une flamme" À ce stade là de bêtise, écoutez.

It is with great sadness that we announce J. Craig Venter has died. 🧪🧬 www.jcvi.org/media-center...

🏅 Nouvelle distinction @emmanuellebayer.bsky.social reçoit la médaille d’argent du @cnrs.fr pour ses travaux en biologie végétale. Comprendre quand une cellule doit s'ouvrir, se fermer, laisser passer ou se protéger : une question au-delà de la biologie 🔬 À découvrir : buff.ly/wtLXvgG

#ResultatScientifique🔎| Certaines bactéries du sol aident les plantes à se défendre contre les maladies 🌿 ✍️ Sébastien Mongrand 👋 @cnrsaquitaine.bsky.social @univbordeaux.bsky.social @lbm-bordeaux.bsky.social 📕 @natplants.nature.com

‼️ Comme chaque année, la #SFBI propose 10 bourses de voyage et des bourses de garde d'enfant(s) pour @jobim2026.bsky.social ℹ️ Retrouvez toutes les informations sur www.sfbi.fr/blog/article... et www.sfbi.fr/blog/article...

Nous recherchons un.e candidat.e pour une thèse à l'interface chimie-biologie financée par l'ANRS. Début souhaité : octobre-décembre 2026. www.linkedin.com/posts/activi...

So it is out! 🎉 I am so excited to share our preprint with Fabio Sterpne and @baam93.bsky.social on the development of a force field for oligourea foldamers, new self-assembling polymers of unnatural amino acids, designed for water desalination membranes. www.biorxiv.org/content/10.6...

I was truly heartbroken to hear about Richard's passing. He was a great mentor and the one who introduced me to the amazing world of proteins. Richard would see the beauty in science, and science in daily life objects, and his vision really shaped my own approach of biomolecular modeling.

Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization [new]

Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization https://www.biorxiv.org/content/10.64898/2026.04.10.717648v1

Full-Length Structural Modeling of Mitofusins with AlphaFold Reveals a Novel Cross-Type Dimerization and Insights into Oligomerization https://www.biorxiv.org/content/10.64898/2026.04.10.717648v1

Elections législatives en Hongrie : le Premier ministre sortant Viktor Orban reconnaît sa défaite face au leader de centre droit Péter Magyar www.franceinfo.fr/monde/europe...

🚀 The af_analysis GUI is out! Load datasets, compute advanced scores (ipSAE, LIS, pDockQ2…), cluster models, and explore PAE matrices + Mol* interactively. Install with: pip install af_analysis[gui] github.com/samuelmurail...

📣 Two weeks left to apply! 📣 I2BC is recruiting new team leaders in molecular and cellular biology, with special attention to multidisciplinary approaches and computational biology. 🧬🧪🔬👩‍🔬🧑‍💻 We provide a great environment with top-notch technological facilities. 🗓️ Apply by April 22, 2026!

Two (or more) PhD student positions are open with me in protein structure evolution (using AI). Please apply/spread the word. su.varbi.com/en/what:job/...

Attention Military Servicemembers If you’re in the US military and seeking discharge or reassignment as a Conscientious Objector, we can help. We’ll work with you to navigate the complex admin process. Services are free of charge. If you’re facing deployment, don’t wait to call us at 800-379-2679.

Is #AI hitting a plateau in structure prediction? Help us find out at CASP17! 🧪🧬 Calling for Targets: Immune Complexes, protein - ligand complexes, RNA/DNA, conformational ensembles, membrane proteins, viral origins, and large complexes. The Rule of Thumb: If AF3 can’t model it, we want it.

Fil RH #CNRS de la semaine #ESR #SNPTES #VeilleESR Des nouvelles du baromètre social au CNRS ? Je grille la politesse à la DRH qui a prévu prochainement une communication sur les résultats du barom social lancé en janv ; et bah, en voici qqs éléments, en exclusivité mondiale ! (pas du tout) 1/14

New preprint🚨 Imagine (re)designing a protein via inverse folding. AF2 predicts the designed sequence to a structure with pLDDT 94 & you get 1.8 Å RMSD to the input. Perfect design? What if I told u that the structure has 4 solvent-exposed Trp and 3 Pro where a Gly should be? Why to be wary🧵👇

La science n'est pas toujours d'accord avec notre intuition. C'est pour ça qu'on fait de la science : pour ne pas seulement suivre le bon sens (celui qui peut nous faire croire que le soleil tourne autour de la Terre).

You asked, we listened. Millions of AI-predicted protein complex structures are now available in the #AlphaFold Database. This spans homodimers from 20 of the most studied species, including humans, as well as the World Health Organization’s priority pathogens list. www.ebi.ac.uk/about/news/t...

"AI" is not a stochastic parrot.🦜 I wrote this piece a couple weeks ago, but it was hard for me to finish up given AI's role in society and war over the past few weeks. I should share it at some point though. Not perfect, but here it is. medium.com/@margarmitch...

holy shit

I wonder... 🤔🤔🧪 #chemsky a) what program did the authors use to make the original (left) figure in the paper? Wild guess, ChatGPT b) how such high school science level of disgrace pass peer review in @nature.com? Note this was Fig.4.a NOT in SI www.nature.com/articles/s41...

We are currently recruiting PhD students, postdocs, and a group leader to join the Institute. If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: [email protected].

The IBS in Grenoble has an opening for a three-year postdoctoral researcher in SNaX team of the DYNAMOP group. The aim of the researcher is to advance data analysis tools for time-resolved serial X-ray crystallography and cryo-EM. For more information, see instruct-eric.org/jobs/postdoc...

We;re hiring Junior Group Leaders! 🔬✨ We’re looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment. www.nki.nl/news-events/...

Des scientifiques découvrent que la violence aurait été inventée avant les jeux vidéos https://www.legorafi.fr/2026/02/20/des-scientifiques-decouvrent-que-la-violence-aurait-ete-inventee-avant-les-jeux-videos/

📌 Enquête MERIT-SFBI sur les conditions de travail des bioinformaticien·ne·s dans les instituts de recherche, universités, établissements d’enseignement et recherche, secteur associatif ou privé 📎 framaforms.org/enquete-meri... ⏳ temps estimé : 20 minutes 📅 date limite de réponse : 31/03/2026

As far as I understand it the current problem with the winter Olympics is that it is snowing...

Updated climate indicators graphics, now including 2025 ed-hawkins.github.io/climate-visu...

Avec les plus spécialistes français de l'épidémiologie des pesticides, nous avons répondu aux propos problématiques de Mme Catherine Hill sur les liens entre cancer et pesticides www.lexpress.fr/sciences-san...

“Moss has been downplayed by Mondrian scholars for years, but she is one of the few top-tier non-figurative British artists from between the wars, and she was the only Briton and the only female artist who appeared in all five Abstraction-Creation journals.” www.theguardian.com/artanddesign...

This is a framing error, NYT. It's different technologies. Chatbots are not the same as the machine learning involved in reading scans (better defined inputs, clearer evaluation of outputs). Calling both AI is like conflating bombs dropped from planes with cars, because they both involve explosions.

Faire des citations scientifiques correctes c'est une choses. Mais encore faut-il qu'elles soient pertinentes. Et en testant sur un sujet sensible… ce n'est pas gagné 1/16

Little blogpost reporting an analysis of recent (2021-2025) retractions of highly-cited papers in relation to #PubPeer comments. deevybee.blogspot.com/2026/02/the-... #retractions #publishing

PhD position in my team at @pasteur.fr ! The selected canddiate will work on the development of new methods combining biophysicial and machine learning modelling for single-cell multi-omics spatiotemporal data. emploi.cnrs.fr/Offres/Docto...

My time in @martinsteinegger.bsky.social's group is ending, but I’m staying in Korea to build a lab at Sungkyunkwan University School of Medicine. If you or someone you know is interested in molecular machine learning and open-source bioinformatics, please reach out. I am hiring! mirdita.org

[STD] Sino-French BioImaging Symposium 2026 Organized between France & China (IRN BioImage), this event is dedicated to imaging for life sciences, with: 🔹An advanced thematic school 🔹A 3-day international symposium 📅When? 14-21, October, 2026 🔗Info: france-bioimaging.org/sfbs-sino-fr...

“The costs of competing for grants can exceed what the grants are worth”, wasting public money. Two models minimise the overhead of grant writing and evaluation: – lottery – per capita funding www.nature.com/articles/d41...