After a long break from social media, I’m finally on Bluesky and have a preprint alert from my lab! doi.org/10.1101/2025...

The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social www.cell.com/developmenta...

We look forward to hearing feedback from the community on our #preprint where we used #NETosis as a platform to show that chromatin decompaction inside the nucleus directly regulates cell mechanics. This work identifies long-range biophysical impacts of chromatin in mammalian cells.

First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1... We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!

Huntingtin binds and bundles F-actin! Thrilled to team up with the Humbert (Sorbonne Université) and Song (KAIST) labs on this discovery. We had a blast doing cryo-ET on this unexpected complex — and now so many new questions lie ahead! #TeamTomo #CryoET #HTT #actin doi.org/10.1126/scia...

1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details

Lay(-ish) summary of our melanoma confinement paper with some behind the scenes details of how this project came about, and what we’re planning to do next (hint: PDAC 🐟). Thanks @nature.com for featuring our work.

To celebrate the summer, our ReSCU-Net paper is out @jcb.org !! Work led by our dungeon master @ray-hawkins.bsky.social, developing a novel neural network architecture and applying it to explore the role of gap junctions in embryonic wound healing in #Drosophila 🧪. shorturl.at/xNRKn

New preprint! We solve a mystery you didn't know existed. Mitotic cells lack new transcription but require ongoing translation. Interphase mRNA half life is only 2-4 hrs. So how do cells arrest in mitosis for hours without depleting their transcriptomes? www.biorxiv.org/content/10.1...

Congratulations to @stefanosala89.bsky.social , with help from @shreya-c.bsky.social al‬ on the optogenetic experiments, for the awesome story! Read the full preprint here: www.biorxiv.org/content/10.1... and thanks for listening!

Yes the NIH people were out in front on this “Using the rescission process, which requires only a simple majority in the Senate, the Republican majorities in the Senate and House can vote to return the unspent funds. That will avoid impoundment and lop billions off the NIH budget” April

Happy to share our new pre-print, "Targeting Cholesterol-Dependent Piezo1 Activation Impairs Amoeboid Migration in Melanoma Cells," led by our fabulous research technician, Sylvia Kuang. www.biorxiv.org/content/10.1...

In new study from Muziyue Wu et al. @oweinerlab.bsky.social, in vivo biochemistry sheds new light on how the WAVE complex templates the characteristic shape of lamellipodial protrusions. rupress.org/jcb/article/... #Cytoskeleton #Actin #Migration #Motility #Biophysics

Intermediate filaments join microtubules in the self-repair club! Great work with in vitro vimentin filaments from @cecileleduc.bsky.social @romet-jegou-lab.bsky.social et al. in @pnas.org: doi.org/10.1073/pnas...

If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape, check out our paper @Nature rdcu.be/eejhZ

With nearly all of Harvard Chan School’s direct federal grants terminated, we are relying on philanthropy to power our research and support our educational programs. Every gift, regardless of size, advances our vision of health, dignity, and justice for every human. Support our work: hsph.me/whygive

Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

I'm so pleased the final version of this research is published! We found that epithelial cells neighoring the cytokinetic furrow regulate the speed and sucess of cell division, while maintaining barrier function and cell packing geometry. Many thanks to the co-authors who contributed! 🐸 #xenopus

Important to celebrate trainee victories: excited to have Holly Merta's @hollymerta.bsky.social paper out! We use TurboID sub-organelle proteomics to map the ER network. We find calmin/CLMN, an ER-to-actin tether regulating focal adhesions & cell motility. www.sciencedirect.com/science/arti...

Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions—now available as a preprint on bioRxiv! 🎉 Huge congrats to Ernest Iu for leading the project, and a special thanks to our amazing collaborators! www.biorxiv.org/content/10.1...

I'm thrilled to finally share my PhD work on understanding how Ca2+ signals regulate the protruding front of the cell. It’s been an incredible journey working alongside all the collaborators. www.biorxiv.org/content/10.1...

The Editors-in-Chief of the 5 @biologists.bsky.social journals have written a joint Editorial, discussing the enormous challenges currently facing researchers in the US and how members of the community can support them through this difficult time. journals.biologists.com/jcs/issue/13...

As scientist I am going through difficult times (this is understatement of the year for me!!). Past one and half months have been horrible, however I am trying to pick myself up and super excited to share my postdoc work with the community! #cellmigration www.biorxiv.org/content/10.1...

🍰Interested in reading more about the study? Here is the N&Vs article written by Nicoletta I. Petridou. 👉🏾https://rdcu.be/ecb3M bit.ly/4bojVlz

Very cool preprint by my colleague Kate McDole and her postdoc Katie Goodwin @cellbiol-mrclmb.bsky.social using beautiful imaging and quantitative methods to understand the wondrous migrations of primordial germ cells in mouse embryos doi.org/10.1101/2025...

Deeply saddened by the passing of Prof. Mike Sheetz, a true leader in Mechanobiology. His groundbreaking work on Kinesin, membrane organization, and mechanotransduction has left an indelible mark. A tremendous loss to science. #Mechanobiology #Science #LaskerAward

Happy to share our new publication in @naturephysics.bsky.social on life and death of eliminated cells! Great collaboration between our CAM team and Doostmohammadi's. Special congrats @lakshmib02.bsky.social and Siavash Monfared! 🎉 www.nature.com/articles/s41...

I get a lot of questions on the #NIH #K99 #postdoc to faculty transition award. Decided to pen my thoughts and experiences towards receiving the K99/R00 - hoping it would be helpful for the community. Please find article link at - debosardarlab.org/blog

Cofilin promotes actin turnover and flexibility to drive coordinated cell movements in vivo https://www.biorxiv.org/content/10.1101/2024.12.17.628979v1

Highlighting our recent paper on how we think doublecortin (green) contributes to growth cone biomechanics in developing neurons for #FluorescenceFriday www.cell.com/current-biol...