Welcome @timcoorens.bsky.social ‪ ‬🇳🇱, our new Research Group Leader. Find out how Tim’s group is exploring using large-scale single-cell and spatial data to trace cell lineages, understand cancer origins, and uncover how mutations drive disease. www.ebi.ac.uk/about/news/p... 🖥️🧬

The cells in our bodies constantly acquire mutations. But what are the patterns of mutations across tissues? How do mutations in normal cells lead to cancer and disease? These are questions we will tackle within the Somatic Mosaicism across Human Tissues (SMaHT) Network, now described in @nature.com

Upcoming #CiMUSseminar on Monday ⤵️ 🗣 Dr. @timcoorens.bsky.social from @ebi.embl.org : 🧪 "Somatic mutations across normal tissues: past, present, future" 📅 June 30, 1 PM 📍 Theatre room, CiMUS #RedeCiGUS #FondosEuropeos ‪@mobilegenomes.bsky.social‬ @usc.gal ‪

🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇

Social media grump Kamila has finally made it onto Bluesky! Please check out my new perspective on metastasis evolution in @natrevcancer.nature.com if you need a reprieve from the news. I tried my best to develop some new conceptual thoughts here, you be the judge whether I succeeded.

If you’ve ever wondered about the statistical significance of differences among mutational signature profiles, check out our new Aggregate Mutation Spectrum Distance (AMSD) preprint co-led by Sam Hart and @alisonfeder.bsky.social with @nalcala.bsky.social www.biorxiv.org/cgi/content/...

Keeping you in the loop! ➰ Our Linktree includes all SMaHT websites and social media accounts for easy and consistent access. Find all our social media accounts in one place: linktr.ee/smahtnetwork

Thrilled to see my #MITS25 talk brought to life by the brilliant 🎨 @atjcagan.bsky.social! Dive into the stellar science from @g-agarwal.bsky.social & co - fresh on bioRxiv: www.biorxiv.org/content/10.1... #Genomics #SomaticEvolution

Read ‘The somatic mutation landscape of normal gastric epithelium’ from @sangerinstitute.bsky.social, @broadinstitute.org, The University of Hong Kong & others in @nature.com ⤵️ www.nature.com/articles/s41...

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our @nature.com paper: www.nature.com/articles/s41...

Excited to share our new preprint demonstrating somatic rescue mutations in a genetic liver disease! [1/12] www.nature.com/articles/s41...

@timcoorens.bsky.social diving into the Bostonian wing of the SMaHT program (a.k.a. 'wicked SMaHT), detailing new sequencing solution for ultra high accuracy duplex sequencing, essential for detecting somatic variation #AGBTgm

Awesome talk by @timcoorens.bsky.social on the detection and interpretation of somatic mutations. Now hiring postdocs! #AGBT25 | #AGBTGM

First large-scale analysis of chemical toxicity in primary human hepatocytes! www.biorxiv.org/content/10.1...

Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years! "Prolonged persistence of mutagenic DNA lesions in somatic cells" www.nature.com/articles/s41...

Our new perspective article describing the human and non-human primate developmental GTEx projects is now out in @nature.com! We outline the scope, vision, opportunities and challenges of these projects here: www.nature.com/articles/s41...

The abstract deadline for "Mutations in Time and Space 2025" is in a week! Please register here: broadinstitute.swoogo.com/mits2025

Spread the word! Registration for the "Mutations in Time and Space" conference is open. The meeting is all about the origins, patterns, and consequences of mutations across cells, individuals, populations, species. Abstract submission deadline is Jan 17th broadinstitute.swoogo.com/mits2025/597...

Let's build a starter pack for childhood cancer research. Please send a message to be added! 🎗️ go.bsky.app/Tpd9QnM