Anna Molofsky Lab
@annamolofskylab.bsky.social
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brain immune communication throughout the lifespan and in neuropsychiatric diseases
Amazing story from
@arimolofskylab.bsky.social
led by the fearless
@nathanec.bsky.social
now online
@nature.com
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19 days ago
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Anna Molofsky Lab
Ardem Patapoutian
3 months ago
I spoke with Jade Hindmon, host of
@kpbssandiego.bsky.social
Midday Edition, about the consequences of the current administrationās cuts to science funding. Please share to help spread the word and raise awareness.
www.kpbs.org/podcasts/kpb...
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Nobel laureate on how Trump's cuts are hurting science
Neuroscientist, biologist and 2021 Nobel Prize winner Ardem Patapoutian joined Midday Edition to talk about how the Trump administration's effort to cut back on science spending is impacting researche...
https://www.kpbs.org/podcasts/kpbs-midday-edition/nobel-laureate-on-how-trumps-cuts-are-hurting-science
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Hiten Madhani
3 months ago
I am saddened by this news. Atul was a vibrant colleague and tireless proponent of using data to unravel the complexity of disease.
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Anna Molofsky Lab
Fran Quintana Lab
4 months ago
New pre-print from our lab here:
www.biorxiv.org/content/10.1...
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Detection of astrocyte epigenetic memory in in vitro systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples
We recently described astrocyte pro-inflammatory epigenetic memory based on multiple complementary in vivo and in vitro studies, and the analysis of multiple sclerosis samples. Based on bioinformatic ...
https://www.biorxiv.org/content/10.1101/2025.05.30.657119v1
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Anna Molofsky Lab
RTN Conference
4 months ago
Have you registered yet for
#ReThinkNeuroimmunology
in October? Speakers include
@aleksdelab.bsky.social
@labschaefer.bsky.social
@annamolofskylab.bsky.social
@itchdoctor.bsky.social
@becherlab.bsky.social
@gocastelobranco.bsky.social
@miriammerad.bsky.social
@kuchroolab.bsky.social
& more
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Pailin Chiaranunt
4 months ago
We're now appreciating how the immune and nervous systems communicate across body & brain, and there's still more to explore! Had a fun time co-writing this with some amazing immunologists and neuroscientists
@nickmroz.bsky.social
@arimolofskylab.bsky.social
@annamolofskylab.bsky.social
šš§
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Cross-regulation between the nervous system and type 2 immunity
The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters, suggesting previously unidentified therapeutic avenues.
https://www.science.org/doi/10.1126/sciimmunol.adp6450
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Anna Molofsky Lab
Waggoner Lab
4 months ago
Review
@sciimmunology.bsky.social
@arimolofskylab.bsky.social
@annamolofskylab.bsky.social
@nickmroz.bsky.social
@phagocyticpai.bsky.social
The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters
www.science.org/doi/10.1126/...
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Seth Thomas Scanlon
4 months ago
This month in
#Science
#Immunology
:
@nickmroz.bsky.social
,
@phagocyticpai.bsky.social
,
@annamolofskylab.bsky.social
, &
@arimolofskylab.bsky.social
pen an insightful & timely Review on crosstalk between the
#nervous
system &
#type2
immunity!
#WeekendRead
#neuroimmunology
#allergy
#Alzheimers
#itch
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Cross-regulation between the nervous system and type 2 immunity
The nervous and type 2 immune systems regulate each other via cytokines and neurotransmitters, suggesting previously unidentified therapeutic avenues.
https://www.science.org/doi/10.1126/sciimmunol.adp6450
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Anna Molofsky Lab
RTN Conference
5 months ago
Speakers include
@aleksdelab.bsky.social
@labschaefer.bsky.social
@annamolofskylab.bsky.social
@itchdoctor.bsky.social
@gocastelobranco.bsky.social
@miriammerad.bsky.social
@kuchroolab.bsky.social
@
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RTN Conference
5 months ago
#ReThinkNeuroimmunology
3 day think tank exploring the biggest discoveries & breakthroughs in neuroimmunology. Organized by
@quintanalabhms.bsky.social
@bethstevenslab.bsky.social
@jonykipnis.bsky.social
@idoamitlab.bsky.social
#RejaneRua
Registrations š
genelayinstitute.org/rtn/
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Anna Molofsky Lab
Ardem Patapoutian
6 months ago
This was the last
@hhmi.org
conference Lilly and Yuh-Nung Jan attended as investigators. They're becoming HHMI emeritus but still run a thriving NIH-funded lab. From cloning the first potassium ion channel (Shaker) to decoding neuronal development, the Jans have made a huge impact.
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Science Friday
6 months ago
Thousands of federal health workers woke up on April 1 to find they had been fired or laid off. Scientists and civil servants at the FDA, CDC, and NIH were let go as part of Robert F. Kennedy Jr.'s pledge to cut jobs at the countryās most important disease-fighting agencies.
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The Department Of Health And Human Services Cuts 10,000 Jobs
The cuts hit multiple agencies, affecting work on HIV, gun violence prevention, vaccines, minority health research, and more.
https://www.sciencefriday.com/segments/hhs-job-cuts-april-1/#segment-transcript
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www.wired.com/story/doctor...
āTo get rid of 11 of our senior PIs ⦠weāre hoping thatās a mistake, because we canāt figure out why they would want to do that,ā
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Doctor Behind Award-Winning Parkinsonās Research Among Scientists Purged From NIH
Leading scientists at the National Institutes of Health, the USās leading medical research agency, were swept up Tuesday in the Trump administrationās latest firing blitz.
https://www.wired.com/story/doctor-breakthrough-parkinsons-research-nih-purge/
6 months ago
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ASM
6 months ago
Removing the top leadership at NIAID, NIH and other health agencies, including the CDC and FDA, will damage Americaās position as a leader in groundbreaking research in disease prevention and treatment. That puts us all at risk. Read our statement:
asm.org/Press-Releas...
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ASM Statement on Removal of NIH & NIAID Leadership
Removing the top leadership at NIAID, NIH and other health agencies including CDC and FDA will damage Americaās position as a leader in groundbreaking research in disease prevention and treatment.
https://asm.org/Press-Releases/2025/April/ASM-Statement-on-Removal-of-NIH-NIAID-Leadership
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Anna Molofsky Lab
Victor Ambros
6 months ago
www.nytimes.com/interactive/...
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Read the Letter
Researchers at academic institutions nationwide say that U.S. science is being dismantled.
https://www.nytimes.com/interactive/2025/03/31/health/scientists-letter.html?smid=nytcore-ios-share
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Go John and Boaz! new gene therapy for Dravet
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6 months ago
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Anna Molofsky Lab
Waggoner Lab
6 months ago
Dysfunctional meningeal lymphatics interfere with the inhibitory synaptic inputs and disrupt excitatory/inhibitory balance on cortical neurons in a microglia-IL-6-dependent manner
@cellcellpress.bsky.social
@jonykipnis.bsky.social
www.cell.com/cell/fulltex...
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Anna Molofsky Lab
Paul Frankland
6 months ago
We have no memories for events from our earliest childhood years (aka infantile amnesia). Is it because we can't form them or can't keep them? Our Perspective on exciting new work from
@tristansyates.bsky.social
and colleagues. Babies form fleeting memories | Science
www.science.org/doi/10.1126/...
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Babies form fleeting memories
The human hippocampus constructs short-lived memories from around 1 year of age
https://www.science.org/doi/10.1126/science.adw1923
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Anna Molofsky Lab
The Transmitter
6 months ago
āThis review belongs in the canon of papers that inspire deep theory work,ā writes Stephanie Palmer about a groundbreaking review by her mentorāAllison Doupeāand Patricia Kuhl that helped the field define the neural and evolutionary dynamics of speech.
#neuroskyence
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Stephanie Palmer on human speech, birdsong and a mentor
A groundbreaking review by Allison Doupe, who was Palmerās mentor, and Patricia Kuhl shaped the field of neural and evolutionary dynamics of speech.
https://www.thetransmitter.org/this-paper-changed-my-life/this-paper-changed-my-life-stephanie-palmer-on-the-ties-between-human-speech-and-birdsong-and-her-informal-life-coach/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250318-tpcml-stephanie-palmer
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Anna Molofsky Lab
Rachael Sirianni, PhD
7 months ago
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. Iām a well funded investigator, and thereās no choice. Science canāt function without the stability of NIH
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Will Ratcliff
7 months ago
This is one of the best features I have seen on blue sky yet- a custom feed of papers from people you follow. I had to un-follow the various biorxiv channels, as it was dominant, but now I am seeing lots of cool papers from people I follow. Great work on this feed,
@paper-feed.bsky.social
team!
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Eric Topol
7 months ago
Cartoon by
@paulnoth.bsky.social
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Dr. Glaucomflecken
7 months ago
Where does TrumpElon think innovation for all their favorite biotech corporations comes from? PCR only exists because somebody was looking for bacteria in hot springs at Yellowstone. Iām just a private practice ophthalmologist who barely understands p values but even I know this shit is important.
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Anna Molofsky Lab
Science Friday
7 months ago
A recent study found that cervical cancer deaths in young women have plummeted since the introduction of the human papillomavirus vaccine.
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As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine
HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.
https://buff.ly/4ajGqaT
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Blake Richards
7 months ago
Dendrite specific linking of memories over time - a cool extension of the work from
@sjo09.bsky.social
,
@denisejcai.bsky.social
, and others:
www.nature.com/articles/s41...
#neuroscience
š§Ŗ
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Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time - Nature Neuroscience
Sehgal et al. show that branch-specific dendritic plasticity mechanisms in the retrosplenial cortex link memories acquired close in time such that, unlike independent memories, linked memories are enc...
https://www.nature.com/articles/s41593-025-01876-8
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Anna Molofsky Lab
Ardem Patapoutian
7 months ago
Finally!
www.nytimes.com/2025/03/08/s...
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Stand Up for Science Rally Sees Mix of Science, Politics and Anxiety
Thousands of protesters gathered in Washington for Stand Up for Science, a rally in response to President Trumpās federal-funding and job cuts.
https://www.nytimes.com/2025/03/08/science/march-for-science-trump-protest.html?smid=nytcore-ios-share&referringSource=articleShare
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Agree! An honor to receive the Bowes award together with
@kampmann.bsky.social
- a testament to the incredible collaborations at
@ucsfhealth.bsky.social
that make our science possible!
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7 months ago
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Anna Molofsky Lab
Haezyll
7 months ago
San Francisco really showed up for
#standupforscience2025
!! Making me proud, Bay Area. š„¼šš
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The Molofsky Lab
#standupforscience2025
San Francisco!
7 months ago
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Dr Susan Johnson
7 months ago
Join us on Friday to hear
@carolynbertozzi.bskyverified.social
speak at
@standupforscience.bsky.social
in SF. Science is for Everyone.
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Anna Molofsky Lab
Stand Up for Science!
7 months ago
STAND UP FOR SCIENCE SPEAKER ANNOUNCEMENT! āļø Dr. Atul Gawande will be speaking at Stand Up for Science in D.C. on March 7th!
@agawande.bsky.social
More speaker announcements coming soon, stay tuned! šāļø
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Shane Liddelow
7 months ago
Congratulations to our long time collaborator and all round excellent human being
@michellemonje.bsky.social
. So very well deservesd!
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Anna Molofsky Lab
Superbugs š¦ š¬š«š§š½
7 months ago
Just saying.
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Anna Molofsky Lab
Matthias Eberl
7 months ago
A reminder that mRNA vaccines are among the greatest scientific and medical breakthroughs ever, with almost unlimited potential against infectious diseases and many different types of cancer.
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Anna Molofsky Lab
Sarafan ChEM-H
7 months ago
New findings from team led by Sophia Shi,
@carolynbertozzi.bskyverified.social
& Tony Wyss-Coray suggest that changes in the sugar coating on the blood-brain barrier may contribute to age-related cognitive decline and brain disease:
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Changes in brainās āsugar shieldā could be key to understanding effects of aging
New findings about the sugary armor on the brainās frontline cells could shed light on cognitive decline and diseases like Alzheimerās ā and open new avenues for treatment.
https://buff.ly/T54ObWN
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Anna Molofsky Lab
Wendy Xueyi Wang
7 months ago
As a student, I was perplexed by a field that dismissed qualitative, classical studiesāthe foundation we build uponāin favor of 'sexy' techniques. I first learnt about axonal beads through Cajal's drawings. I wonder what else we've forgotten. Cross-posting some images to bsky.
#FluorescenceFriday
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Anna Molofsky Lab
Sean J. Morrison
7 months ago
What do Americans need more: better treatments for cancer, Alzheimer's disease, diabetes, infectious diseases and other major public health problems or a way to send Musk to Mars?
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Ardem Patapoutian
7 months ago
Who benefits from US funding uncertainty? Hours after posting this, I got an email inviting me to China with a āpackage to support my research for 20 years.ā Apparently, generous offers are available to all good scientists!š§Ŗš§
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standupforscience2025.org/sacramento-ca/
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Sacramento, CA
Location: California State Capitol Building 1305 10th St, Sacramento, CA, United States Address: 1305 10th St, Sacramento, CA 95814 Time: 12 PM-4PM Other Information: Event will be taking place on ā¦
https://standupforscience2025.org/sacramento-ca/
7 months ago
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Jeremy Berg
7 months ago
New York Times article now up on Federal Register stuff.
www.nytimes.com/2025/02/21/s...
1/n
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Trump Administration Stalls Scientific Research Despite Court Ruling (Gift Article)
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
https://www.nytimes.com/2025/02/21/science/nih-research-funding-delays.html?unlocked_article_code=1.yk4.qNQA.zVPAsVztAZ3p&smid=url-share
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Dr. Becca
7 months ago
šš»šš»šš»šš»
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Senator Patty Murray
7 months ago
Trump's illegal NIH cuts mean cancer researchers would be laid off, sick kids going without treatment, and more. These cuts would be DEVASTATING for lifesaving research. Some Republicans have said they agreeābut they just blocked my amendment to reverse Trump's NIH cuts anyway.
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Oscar Marcelo Lazo
7 months ago
First splicing therapy in utero for spinal motor atrophy (SMA). Massive achievement.
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Anna Molofsky Lab
TRAstonDrs
7 months ago
#Medskyš§Ŗ
#idsky
#episky
#neurosky
#immunosky
#publichealth
Accumulating evidence suggests that adult vaccinations can reduce the risk of developing latent Alzheimerās disease & Alzheimerās disease related dementias.
content.iospress.com/articles/jou...
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The Impact of Routine Vaccinations on Alzheimerās Disease Risk in Persons 65 Years and Older: A Claims-Based Cohort Study using Propensity Score Matching - IOS Press
Background: Accumulating evidence suggests that adult vaccinations can reduce the risk of developing Alzheimerās disease (AD) and Alzheimerās disease related dementias. Objective: To compare the risk ...
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad221231
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www.thetransmitter.org/funding/fede...
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Federal Register hold makes āend runā around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
https://www.thetransmitter.org/funding/federal-register-hold-makes-end-run-around-court-pause-on-nih-funding-freeze/
7 months ago
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Anna Molofsky Lab
Stand Up for Science!
8 months ago
Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone
#standupforscience2025
on March 7th, both in DC and locations nationwide!
#scienceforall
#sciencenotsilence
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Stand Up for Science!
7 months ago
The MMR vaccine is 97% effective at preventing measles infection. But infants under 12 months old are not eligible for the vaccine, leaving them vulnerable. When measles spreads due to low vaccination rates, it puts our youngestāand most defenselessāchildren at the greatest risk.
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Anna Molofsky Lab
Colette Delawalla
8 months ago
Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.
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Anna Molofsky Lab
Eric Topol
8 months ago
It's not "Breaking News" now, since it was announced by NIH yesterday. But it is breaking.......
washingtonpost.com/health/2025/...
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