What's the state-of-the-art in DIA XL-MS? #Proteomics #TeamMassSpec

“Jane Goodall was an amazing scientist who inspired people to see the natural world in a new way. She helped us to look at the animal kingdom with fresh eyes and with greater respect.

This is pretty crazy, study models millions of indirect hurricane deaths potentially driving/contributing to the life expectancy disparity in the US: www.nature.com/articles/s41...

And after 40 minutes of cringe-Thunderous applause from the generals! Just kidding. Total silence. 👀 🦗 🦗

Hey #TeamMassSpec, Many non-human proteomics studies still search against taxon-filtered FASTAs. ❌ Redundant sequences ❌ Inflated search space ✅ Reference proteomes cut redundancy, improve annotation, and make results comparable. 👉 Time to move beyond taxon filters. #proteomics #massspec #uniprot

A pretty cool examination of the OLink Reveal 1000+ protein plasma assay pubs.acs.org/doi/full/10....

Anyone kicking the tires on the new 96 tip head from Opentrons? opentrons.com/products/ope... #Proteomics #TeamMassSpec

Full circle moment! While visiting ASBMB for a Maximizing Access Committee meeting, @garcialabms.bsky.social spotted one of his early JBC papers. www.jbc.org/article/S002... Do you remember the thrill of your early publications? Share below! @asbmbjournals.bsky.social #asbmbJBC #TeamMassSpec

🌟 Meet Tina Chong, our Senior Applications Manager! She bridges customer goals with Microscoop workflows—helping uncover proteins that matter in cancer research. #Proteomics #TeamSyncell

New AI tool can predict a person’s risk of more than 1,000 diseases, say experts www.theguardian.com/science/2025...

The #BMSS2025 conference was a fantastic experience! 😀 It was so much fun to listen to such great talks, see so many wonderful posters and experience true enthusiasm for science. Glad I could share our latest XL-MS results with you!🙂🙃 #teammassspec #massspec #chemsky #academicsky

Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline Presenters: Eduard Sabidó and Brendan MacLean When: Tuesday, September 16, 8am (Pacific Time) Register Now ... skyline.ms/project/home... #massspec #proteomics

Recommend crosslinking read from the Rappsilber lab www.sciencedirect.com/science/arti... The circle view is particularly cool IMO.

More from the crazy world of crosslinking. If you thought xiNET (crosslinkviewer.org/index.php) was cool then xiVIEW will have you falling off your chair! xiview.org/index.php XiVIEW is a very advanced tool and well worth checking out. #Proteomics #TeamMassSpec

Time to read up on all things coming out of this lab: www.rappsilberlab.org #Proteomics #TeamMassSpec

Going down the Crosslinking rabbit hole today. This is amazing: www.nature.com/articles/s41... And this is sweet: colab.research.google.com/github/Rapps...

Recently stumbled upon this tool for mapping cross links. Super easy to use and really nice output. AND it runs locally! #Proteomics #TeamMassSpec crosslinkviewer.org/index.php

Contrasting cell count and biomass distributions by cell type: ◼️ Human cell size and count are nearly inversely related. More quantitatively, ... 🧵

If you’re looking for some exciting reading to take into the weekend with you, please check out Haley’s first, 1st-author paper published in Science of the Total Environment this week! You won’t want to miss these wildfire smoke induced lipid changes!🔥💨 www.sciencedirect.com/science/arti...

Nice Figure 2a from Dou et al 2019 "Automated Nanoflow Two-Dimensional..." Reverse phase chromatography and protonated molecule of DDM. pubs.acs.org/doi/abs/10.1...

A great day for remote Targeted Protein Degradation learning. This conference is free to attend and has some of fantastic speakers. #Proteomics #TeamMassSpec www.danafarbertargetedproteindegradation.org

Lilly launches TuneLab, an AI/ML platform for drug discovery tunelab.lilly.com

Probabilistic scoring of DIA matches without spectral deconvolution? Not only is it possible, we're working on implementing it in Mascot DIA. www.matrixscience.com/blog/probabi... #proteomics #massspec

In case you missed it. Researchers synthesize a new allotrope of carbon | EurekAlert! www.eurekalert.org/news-release...

More cool #chemistry from @purduechemistry.bsky.social www.chem.purdue.edu/media/news/2... #TeamMassSpec

@gavinnewsom.bsky.social Bought any milk recently Gavin? Make America sour again dude. So expensive and aging prematurely.... I don't like that dude. Nobody likes sour milk. #Sourmilk

Don't abandon science folks, it won't abandon you! Japan has opened its first osmotic power plant – so what is it and how does it work? www.theguardian.com/world/2025/a...

A must read for the target identification folks. #TeamMassSpec

New Preprint: High-intensity 365 nm irradiation accelerates photoreactions in living cells by up to 1000×. We show protein–drug 💊, –protein 💪, –DNA 🧬, –RNA 🧬 crosslinking within seconds, and analysis by #massspec for #proteomics, #chembio, #chromatin and #RNAbiology. www.biorxiv.org/content/10.1...

It’s about racism and pretending it’s not about racism will not magically erase the racism

Can we use the Blockchain to improve reproducibility in #proteomics? Specifically, can we use the Blockchain to store details of databases used for searches? Modern DIA searches are several steps from a traditional fasta file. A unified library could help with credibility.

Putin in Alaska flagged that US imports from Russia are up since Trump became President. This is just his usual misinformation and an attempt to divide the US and Europe. Imports from Russia are at Biden administration levels and fell most recently. US exports to Russia are zero. Misinformation...

The latest pick for head of the fed is in line with expectations. Hey, bro's good at math and grrrrreat on TV.

Last but most certainly not least, The President’s Innovator Award 2025 goes to Dr. Nicki Packer, Macquarie University, Sydney, Australia 👏🥂👏🥂

5/5 The 2025 ASBMB Molecular and Cellular Proteomics Lectureship goes to Dr. Rebekah Gundry @gundrylab.bsky.social , University of Nebraska Medical Center 👏👏🥂

4/5 The Glycobiology Significant Achievement Award: Dr. Ryan Flynn @raflynn5.bsky.social, Harvard University, 👏👏🥂

2/5 The 2025 Karl Meyer Lectureship Award goes to Dr. Laura Kiessling @laurakiessling.bsky.social, MIT 👏👏🥂,

Does anyone have a reference for improvements in MS3 performance across Thermo instrument offerings? #Proteomics #TeamMassSpec

Carol Robinson on Desert Island Discs - have a listen friends: www.bbc.co.uk/sounds/play/... An inspirational scientist & friend. An example of combining scientific excellence, courage, hard work and really importantly; kindness. (Yes I’m biased, but it’s true nevertheless) @kavlioxford.bsky.social

@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

Success! We've now run almost 2000 mouse cortex and plasma samples through this assay so expect more publications referencing it very soon. Much thanks to the Skyline team and @maccoss.bsky.social #modelad #teammassspec #proteomics www.tandfonline.com/doi/full/10....

RIP OZZY

If you learn one thing about LLMs this week it should be this: youtu.be/TUjQuC4ugak?... What does it mean? Try, you're not wave, you're a graph database. #AI #LLM

Can AI reveal risk & co-pathology of multiple neurodegenerative diseases from a single blood sample? We explored AI-based diagnostic power on high rank plasma proteomics (N=17,170). www.medrxiv.org/content/10.1... #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #neurology

It’s finally out! 18 million year old enamel proteins from the Turkana Basin, Kenya @paleoproteomicist.bsky.social #paleoproteomics #proteomics 🧪 ⚒️ www.nature.com/articles/s41...

Microscoop is live in Nijmegen! A big thank you to the Roepman Lab and the Syncell team for an exciting and productive week of installation, training, and scientific exchange! From biovalidation to imaging and seminar discussions, the enthusiasm was contagious. #Microscoop

For folks wondering where the hot #proteomics is happening send your CV to Monte Rosa Therapeutics. Lots of cool stuff going on there cen.acs.org/pharmaceutic...

Stopped in to see a friend and see if he was having any fireworks for the 4th of July... that would be a yes #Merica #4thofJuly Happy Independence Day folks!