New paper out at the Journal of Psychopathology and Clinical Science! We examined unconditional & event-related changes in pathological vs normal-range personality using 4 metrics to compare their developmental links, how these vary with life events, and whether unique effects emerge across metrics

I'm looking for a PhD student to do some trailblazing at the frontier of personality genomics and lifespan gene-environment transactions (start Fall 2026)! If you want to work with me: psychology.msu.edu/graduatestud... (PS @drmeltemyucel.bsky.social is taking a student too, in moral psych/dev!)

BIG PREPRINT🔬 In a newly founded consortium we show that we barely know anything about the neurobiology underlying emotion regulation capacity! (40 fmri samples, N=2175) So, time-out for prefrontal cortex explanations! And we also show why this might be the case 🧵 www.biorxiv.org/content/10.1...

An updated preprint of our Borderline Personality Disorder GWAS is now online: www.medrxiv.org/content/10.1...

🚨 Our parent-of-origin study is out in Nature! 🧬 Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss. 🔗 www.nature.com/articles/s41... Highlights below!

New pre-print online: Imputing parental genotypes through Mendelian Imputation: Ethical and Legal Considerations osf.io/preprints/ps...

Very exciting preprint by @axel-schmidt.bsky.social, @kuludwig.bsky.social and team! Check out Kerstin's thread for overview

Very exciting preprint by @axel-schmidt.bsky.social, @kuludwig.bsky.social and team! Check out Kerstin's thread for overview

New preprint by Xiaopu Zhang! www.biorxiv.org/content/10.1... @jordanatbell.bsky.social @ntrbiopsy.bsky.social

🔔Paper alert! Extremely excited to share a preprint from our lab! Spearheaded by @axel-schmidt.bsky.social, a super talented medical & computational geneticist, we studied latent Epstein-Barr virus (EBV) infection at population-scale. Interested in how this works & what we found? Read along! 👇

Our project, looking at the genetic relationships between immune diseases and psychiatric disorders, has finally been published! Now with gene expression analyses as well as additional sensitivity analyses, thanks to reviewers. Find the full article here: www.nature.com/articles/s41...

PhD position in my group at @fau.de, as part of my @erc.europa.eu Consolidator project PAR2. German is not essential but an interest in social science genetics would be great! Sharing would be much appreciated ❤️ www.jobs.fau.de/jobs/phd-pos...

🚨New preprint is out! How do genetic effects on complex traits change with age? In this work, we compare different approaches to obtain age-varying genetic effects, and show how design and modeling choices can impact the conclusions we draw. shorturl.at/17snd A thread 🧵👇

Our paper, MR-link-2 has just been published! Offering pleiotropy robust Mendelian randomization from a single region! www.nature.com/articles/s41...

New preprint!🚨 "“The Contribution of Common and Rare Genetic Variation to Emotional and Behavioural Symptoms in Childhood and Adolescence” is out on medRxiv. www.medrxiv.org/content/10.1... Thread 👇

While the world watches Israel's war with Iran, Netanyahu's extremist government continues to starve and massacre Palestinians in Gaza. Today, Israeli forces again opened fire on people desperately trying to collect food aid, killing dozens. Over 56,000 have been killed so far.

Intergenerational Transmission of Parental Mental Health and Wellbeing Traits on Offspring Emotional and Behavioural Difficulties https://www.medrxiv.org/content/10.1101/2025.06.17.25329751v1

Looking for your next research position? We're recruiting two genetic epidemiologists to work on two projects at the Division of Psychiatry at UCL, part of the growing UCL Human Genomics group.

Thanks @eivindy.bsky.social! My first foray into the mysterious world of #SelectionBias. Very happy to receive feedback, and to discuss opportunities for improving/expanding this work!

🧵 THREAD: Preprint from @chrisrayner.bsky.social reveals how to fix selection bias in the Norwegian #MoBa study using population-wide registry data! For the first time, we can quantify and adjust for selection bias in this major epidemiological resource. Spread the good news! osf.io/preprints/os...

Our paper "A fragmented field" has just been accepted at AMPPS. We find it's not just you, psychology is really getting more confusing (construct and measure fragmentation is rising). We updated the preprint with the (substantial) revision, please check it out. osf.io/preprints/ps...

Last week, our new paper on indirect assortative mating was published.🍾 Let’s take a closer look at what this means, why it matters, and what we found (🧵/32): www.nature.com/articles/s41...

1/13 New preprint out! We developed methods to test a key assumption in family-based genetic studies: that siblings don’t genetically influence each other’s traits. Spoiler: mostly they don’t, but there’s a twist with ADHD ratings at age 3 👶 osf.io/preprints/ps...

Looking forward to running a session alongside @tommetherell.com @zefreeman.com on the challenges of public engagement in a post-truth society during #SIPS2025 in Budapest! Hope to see you there for an open and informative discussion!

🎓 Multiple exciting job openings at the Department of Complex Trait Genetics at VU Amsterdam: Application for Two PhD Positions in Statistical Genetics: t.co/0Cy3KF75lI Application for Postdoc Statistical Genetics: t.co/ENI5KeI6yF Application for Postdoc Bioinformatics: t.co/qOLaauKNLV

We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data        Generous starting package 💰 shorturl.at/FAk6n

New paper with @paulhufe.net Astrid Sandsør and Nicolai Borgen 📝 Causal evidence for gene-environment interaction based on: 🧬 Exogenous within-family genetic differences 🏫 Exogenous variation in school value added

Now published! Congrats Yon Ho on this huge lift conducting dozens of GWAS in Korea and performing meta-analyses with other Asian biobanks reaching a sample size comparable to UK Biobank. The fine-mapping, novel loci, and ancestry-enriched discoveries are very cool. www.nature.com/articles/s41...

Very pleased to see our paper describing the @ukbiobank.bsky.social second online mental health questionnaire has now been published in @plosone.org! This describes the origin of the resource as well as the data. Fantastic work by Katrina Davis in leading this 👏👏👏 dx.plos.org/10.1371/jour...

Did you know just how intertwined anxiety and depression can be? Studies show that >60% of people with anxiety also experience depression, and vice versa. This is called #comorbidity (1/4)

Live from the conference continues, we are now at 98 club karaoke, first come first serve! @essgn.bsky.social

We are looking for a post-doc/research fellow working on non-bullshit, reality-centered AI. Meaning: unique nationwide EHR and -omics with the possibility to recontact people and prospectively test multimodal AI approaches. jobs.helsinki.fi/job/Helsinki... @FIMM_UH @FinnGen_FI

PGI Repository v2.0 preprint out! A 🧵 on the main results and updates @robel-alemu.bsky.social @paturley.bsky.social @alextisyoung.bsky.social

Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...

Happy to share our new study on genetic & environmental contributors to age-related decline in ~100K UK Biobank participants! Here, we used simulation work + longitudinal GWAS and downstream analyses to explore risks involved in cognitive/physical decline (1/)🧵🧵 shorturl.at/99gqL

This is VERY big genetics & health news, Regeneron (Pharmaceutical company with v strong genetics in medicine arm) is going to buy 23andme. investor.regeneron.com/news-release...

Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects! www.biorxiv.org/content/10.1...

🎉We are thrilled to have 2000+ datasets on the #AtlasLongitudinalDatasets! New datasets, global users, and a whole lot more on the way 🌍💡 👀 Keep watching this space for exciting updates. 🔗 atlaslongitudinaldatasets.ac.uk

🚨 NEW PREPRINT ALERT! 🚨 Very pleased to have the latest @pgcgenetics.bsky.social eating disorders GWAS now out on medrxiv! Featuring one first author from our group (Sang Hyuck) and one senior author (Joni), alongside 168 others! www.medrxiv.org/content/10.1...

Work on the British cohort studies never stops. Thank you to the thousands of participants and researchers who continue to sustain this invaluable resource.

still a couple of days left to apply!

Our gene discovery project on age at onset of walking is out today! Find the paper here www.nature.com/articles/s41... Huge thanks to the cohorts, collaborators & coauthors, in particular first author Dr Anna Gui 1/n

Happy to share our new (open access) article in the Canadian Journal of Economics on people’s willingness to donate DNA for science and its relationship with economic incentives and preferences. A brief thread on what we learned (1/4): doi.org/10.1111/caje...

When do epigenetics matter most for child health? At birth, predicting later development? Or are effects stronger, when measured at the same time as the child health outcome? Our new findings suggest that the answer may depend on how you define relevance. doi.org/10.1186/s13073-025-01451-7

Very excited to give a virtual talk as part of the @eshg.bsky.social webinar series tomorrow at 4pm (CEST). If you want to listen in, register here: wma.eventsair.com/eshg-webinar... I will talk about all the exciting things we can learn from GWAS summary statistics...

Excited to share that the second paper from my PhD has just been published in @NatMentHealth!🧠🧵 We modelled depression symptom networks in >35k teenagers to derive their 'network temperature' and found evidence symptom stabilisation across adolescence... www.nature.com/articles/s44...

📣 New Preprint: Protocol for Depression Genetics in Africa (DepGenAfrica), supported by @wellcometrust.bsky.social osf.io/preprints/os...

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!

Our in-person Mendelian randomisation course is back at University College London this autumn. Join us in Bloomsbury, 16th-18th September 2025. Tutors: Emma Anderson, Dylan Williams, Neil Davies Guest lecturer: Eleanor Sanderson onlinestore.ucl.ac.uk/conferences-...