Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...

This therapy builds on research from Carlos Belmonte, @neuroviana.bsky.social and colleagues, who showed how corneal cold receptors drive tear production and identified TRPM8 as a target. Once again showcasing the international nature of scientific progress.

Join us if you want to learn about #microglia!

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

My quote of the day I am patient with stupidity but not with those who are proud of it. Edith Sitwell

The Confocal Room

#ScienceJobs Great opportunity to cutting edge science with a really great mentor!!

The Anne West lab at Duke is hiring a postdoc to work on nuclear cell biology in neurogenesis. Please help me spread the word! Applications to [email protected].

📢 We are seeking a Head of the Human Brain Organoid Core Facility as part of our Severo Ochoa Centre of Excellence 2023–2026 program. This is a prestigious leadership opportunity in advanced neuroscience research! 👇 in.umh-csic.es/es/ofertas/t... @csic.es @umh.es @sommalliance.bsky.social

🎉 Enhorabuena al recién nombrado hoy Dr. Rafael Soler Ortuño por su defensa de #TesisIN y felicitaciones a su director de Tesis, el Dr. Víctor Borrell @borrell-lab.bsky.social 🎉 @umh.es @csic.es @dicv.csic.es

Thanks to #PremiosReiJaumeI for enabling visits from the outstanding award jury to research centers across the Comunitat Valenciana. At @neuroalc.bsky.social, we were honored to welcome: @ardemp.bskyverified.social ( #NobelPrize 2021) & Erika Pastrana (Editorial Director @natureportfolio.nature.com)

Hoy ha arrancado @pintofscience.es y #Alicante es una de las ciudades que participa 🙌 No te pierdas las charlas de los investigadores del @neuroalc.bsky.social 👇👀 #PINT25ALC

New preprint alert 📣 #Cerebellum, organoid, autism & brain evolution 🧪 🧫🧠🧬 Collaboration with G. Testa; fruit of years of work by smart students, led by postdoc Davide Aprile. Organoids to understand better the developmental basis of autism (focus: CHD8) & sapiens brain evolution (focus: CADPS2) 🧵

¡Muy orgullosos de acompañar a Félix Leroy @leroyfelix.bsky.social en la entrega del premio Alberto Sols al mejor trabajo científico! 👋👋 🎉Enhorabuena por este merecido reconocimiento 🎉 @csic.es @umh.es @dicv.csic.es

It has been an absolute pleasure for our lab to attend #ECCN2025 for the first time this year. We had meaningful discussions and learned a lot from a vibrant community tackling tough questions on brain evolution and development! Super excited for what lies ahead!

I'm still processing all the amazing interactions and possibilities this meeting brought. Different fields and expertise converging in a common interest: brain evolution. It was fantastic. Thanks to the organizers @borrell-lab.bsky.social @k4tj4.bsky.social ( Nerea Moreno, Fernando and Zoltan)

Today, Dr. Kristian Franze from @fau.de offered us a fantastic #SeminarsIN about the chemo-mechanical regulation of brain development. Great talk, thank you! 👏👏 @borrell-lab.bsky.social @csic.es @umh.es @dicv.csic.es

Brad Colquitt @bradcolquitt.bsky.social showing us how to enable birdsong precision and speed through gene regulatory co-option at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Over 100 scientists gathered in Alicante for #ECCN2025 to explore how nervous systems evolve across species. The 11th European Conference on Comparative #Neurobiology featured cutting-edge research from around the world 👇 in.umh-csic.es/en/over-200-... #BrainEvolution @borrell-lab.bsky.social

Pavel Němec taking us on a ride through an impressive number of species across the avian and fish kingdoms in his talk on the evolution of brain neuron numbers in jawed vertebrates. With amazing @kkverkova.bsky.social #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Ornella Bertrand @ornellabertrand.bsky.social takes us on a journey exploring the evolutionary history of the mammalian brain – how behaviour and adaptation have shaped its structure over millions of years in her talk (and poster) at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social

Alain Goriely @alaingoriely.bsky.social takes us into the intricate world of connections, unraveling the multiscale principles of neuronal path-finding at #ECCN2025 @r3rt0.bsky.social @borrell-lab.bsky.social @zoltan-molnar.bsky.social

How can the brain make new connectivity pathways when traditional ones are disrupted? Fantastic talk by @laurarosefenlon.bsky.social showing us how Marsupials reveal the evolutionary diversity of neocortical development. @rsuarezsaa.bsky.social #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social

#ECCN2025 posters were all absolutely fantastic! 🥳 Congrats to best poster&flash talk awardees @giacomogattoni.bsky.social @rsuarezsaa.bsky.social @kkverkova.bsky.social Anh T Trihn Kindly sponsored by BBE Karger, organised by amazing Nerea Moreno-García @borrell-lab.bsky.social @r3rt0.bsky.social

Carmen Falcone @carmenfalcone.bsky.social giving a fantastic talk at #ECCN2025 on Varicose projection astrocytes: from evolution to neuroinflammation @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Brought a bit of #glia to this great evolutionary meeting. It was fun to be part of this session, together with Bradley Colquitt and Auguste von Bayern, chaired by the amazing @k4tj4.bsky.social 🤩 Thanks @borrell-lab.bsky.social and the other organizers for the invitation! #ECCN2025

Many thanks to @borrell-lab.bsky.social @k4tj4.bsky.social @r3rt0.bsky.social for organising #ECCN2025 and bringing together such a variety of research and species! I truly enjoyed the experience! Stay tuned for the next edition #ECCN2028 in Leuven! (Or Tenerife, still have to decide hehe)

Learning so much at the ECCN meeting — even better with the great company of several SEBD colleagues! Exciting science, inspiring talks, and great conversations @sebioldev.bsky.social #ECCN2025 @borrell-lab.bsky.social @neuroalc.bsky.social

Takashi Namba @takashi-namba.bsky.social talking about the metabolic microenvironment for the evolution and development of the human neocortex at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Laurent Nguyen giving us an evo-devo perspective on cortical interneuron migration in the forebrain. at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Alain Chédotal @alainchedotal.bsky.social giving a beautiful presentation with amazing data on the Development and evolution of the visual system. at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Enjoying the beautiful and inspiring talks presented at the #ECCN2025. Learning from the bests! @borrell-lab.bsky.social eccn2025.umh.es

Maude Baldwin tracing the Functional evolution of the taste and digestive system in birds at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Eloisa Herrera sharing with us a beautiful presentation on Evo-Devo Insights into the Emergence of Binocular Circuits at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Berta Alsina @bertaalsinalab.bsky.social kicking of the morning session on the evolution of sensory systems with the morphogenesis of the inner ear – similarities and differences between amniotes and anamniotes #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Diving into Multiome approaches to understand gene specification networks in the zebrafish retina with Juan Ramon Martínez-Morales @jrmarmor.bsky.social at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Henrik Kaessmann @kaessmannlab.bsky.social taking us on an amazing journey to the origins and evolution of the vertebrate brain at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Modern sharks as our best mirror to our jawed common ancestor – @idoiaeu.bsky.social talks about the catshark embryo as a model to study the origin and evolution of the vertebrate telencephalon at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Differences in neurogenesis across species appear since the earliest stages of development, as shows @cohouart.bsky.social #ECCN2025 @borrell-lab.bsky.social @k4tj4.bsky.social

Tadashi Nomura showing how Changes in conserved developmental mechanisms underlie mammalian and non-mammalian-specific pallial structures, kicking off the session on the evolution of brain development at #ECCN2025 . @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Fernando Garcia-Moreno giving a beautiful presentation showing how neurogenesis and transcriptomics can provide a new understanding of brain evolution with amazing data from mammalian and avian species at #ECCN2025 @borrell-lab.bsky.social @r3rt0.bsky.social @zoltan-molnar.bsky.social

Great talk by Víctor Borrell @borrell-lab.bsky.social on the evolutionary convergence and divergence of cortical neurogenesis, including amazing data across ferrets, mice, chicken, and snakes. 🐭 🐣 🐍 #ECCN2025 @r3rt0.bsky.social @zoltan-molnar.bsky.social

Nuria Flames showing how C. Elegans can be used to learn about the mechanisms underlying evolutionary adaptations of homologous neuronal cell types, #ECCN2025 @borrell-lab.bsky.social @k4tj4.bsky.social

Eduardo Leyva on "Programming and reprogramming the nervous system via CUT homeobox genes" at #ECCN2025, @k4tj4.bsky.social @borrell-lab.bsky.social

Víctor @borrell-lab.bsky.social kicking off #ECCN2025 in Alicante. Looking forward to an amazing meeting with fantastic speakers covering a large range of the phylogenetic tree. First up: Gilles Laurent on Evolutionary perspectives on circuits for vision and sleep, including octopus camouflaging 😍

How do large brains emerge in different branches of the phylogenetic tree? @eveseuntjens.bsky.social talks about octopuses at #ECCN2025 @k4tj4.bsky.social @borrell-lab.bsky.social

The ERC welcomes the offer of substantial additional budget from @ec.europa.eu for the development of a new ERC funding instrument offering larger, longer-term grants, as announced by President Ursula Von der Leyen at the Sorbonne this morning. 👉 europa.eu/!NTYTTV

Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...