Alzheimer’s disease is shaped by interactions between Aβ and tau, which together drive neurodegeneration. However, how these processes unfold across brain regions and over time remains unclear. 2/

‼️ New preprint ‼️ How do amyloid-β (Aβ) and tau drive Alzheimer’s disease over time? We introduce a parsimonious, mechanism-based dynamical ATN (dATN) model to simulate longitudinal imaging biomarkers. A short thread 👇 Preprint: www.biorxiv.org/content/10.6...

In-person tickets open: The Shape of #Gravity: Why On Earth Are Planets Spherical? Professor Alain Goriely* explores how gravity shapes planets, from Earth’s squashed form to the limits of spherical worlds https://gres.hm/shape-gravity *also of Oxford Mathematics‬ #astronomy #maths

0️⃣1️⃣1️⃣2️⃣3️⃣5️⃣8️⃣🌺🥬🌱🌀 @alaingoriely.bsky.social on the Shape of Plants @greshamcollege.bsky.social (featuring our work with @christhorogood.bsky.social on Nepenthes at the end www.pnas.org/doi/10.1073/...) www.gresham.ac.uk/watch-now/sh...

An unlikely collab between famous rapper J Cole and (very famous) mathematician Andrew Wiles (or Big AW as he is known in the rap world). www.youtube.com/watch?si=qir...

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Why is it that small animals like insects have a landspace body plan when viewed head-on, but larger animals like elephants are taller than wide? With @m-v.bsky.social, we find out in our new preprint titled 'Size and shape of terrestrial animals' - arxiv.org/html/2602.00...

The Academy for the Mathematical Sciences has announced its first cohort of fellows, 100 in total from academia, teaching, science communication and business. Twelve of those fellows are from Oxford. Who's who: www.maths.ox.ac.uk/node/80068

Clash of the titans. Chaplain and Preziosi on my left at 856 pages vs Keener and Sneyd on my right at 1222 pages.

Global brain activity links subcortical degeneration to cortical tau progressively across Braak regions over early Alzheimer disease stages https://www.biorxiv.org/content/10.64898/2026.01.23.701360v1

Job alert🚨I am advertising a 2-year postdoctoral position to work on the mathematics of plant morphogenesis @mpipz.bsky.social. Candidates with interests in mathematical modelling, mechanics, or biophysics are strongly encouraged to apply. 🌱Reposts are appreciated! jobs.mpipz.mpg.de/jobposting/4...

In a sarcastic book (Histoire de l’Astronomie du dix-huitième siècle) published in 1827, Joseph Delambre writes about mathematicians: "Les géomètres, qui ne calculent rien, s’imaginent qu’un problème est résolu quand ils l’ont renfermé dans une formule dont personne ne veut faire usage."

Register for the LMS/@ima-maths.bsky.social Crighton Award Lecture on 13 May at The Royal Society. . The lecture will be given by Alain Goriely (@oxfordmathematics.bsky.social), winner of the 2025 award for his contributions to the public understanding of maths. ➡️ www.lms.ac.uk/events/lms-i...

❗🧠 New review in IEEE RBME How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression "Network models of neurodegeneration: bridging neuronal dynamics and disease progression" ieeexplore.ieee.org/document/113...

We all have to compromise and it starts right at the top with our brains. Dani Bassett will demonstrate how the principle of network economy informs our study of neural system function in health and disease and provides a lens on neural computation. Book: www.maths.ox.ac.uk/node/79854

Christiana's first Mathematical Physiology lecture was so popular (aside from the occasional comment that university teaching isn't what it was in Isaac Newton's day etc.) that we'd thought you tell you that the second lecture is now available. youtu.be/3u1GSYOQEL8

We're starting our 2026 student lectures for the wider public with eight lectures from Christiana Mavroyiakoumou's 4th year Mathematical Physiology course. Watch lecture 1: youtu.be/lgrwTpgeJo8 And look out for lectures on dynamics, geometry, special relativity and more.

Interested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics

Cats are mathematically smart. They can count to nine, they are rarely heading for a fall, and when they are, they always land on their feet. But sometimes they just don't know whether they are coming or going.

Here is the link to download the PDF of my course#5 on Biological computation. I present & discuss Self-tuning, Adaptation and Learning in biological (non-neuronal) systems, in particular during embryonic development. This course contains various personal ideas/proposals. tinyurl.com/hcpwsbtm

In-person tickets open: The Shape of Shells 🐚 https://gres.hm/shape-shells Seashells, built by molluscs layer by layer, follow simple mathematical rules that create beautiful self-similar forms. Prof Alain Goriely* explains how we get various shapes, spines & wrinkles *also of Oxford Mathematics

Our latest vacancies capture the scope of the mathematics that takes place in our home, the Andrew Wiles Building. Such a range of research areas - we have 16 research groups - enable our mathematicians to share ideas with colleagues working across the discipline. www.maths.ox.ac.uk/vacancies

New maps of brain folds from 26 carnivoran species show how differences in behaviour and ecology appear in their anatomy. buff.ly/IQvBHbh

Where on earth is the best laboratory to demonstrate the beauty of fluid dynamics? Actually, it’s not on Earth. Here is the story of the soft cell. Read more ⬇️ https://www.maths.ox.ac.uk/node/74308 @oxfordmathematics.bsky.social | Axiom Space | NASA

Let's break some structures imposed by higher-order interactions! We compute how things deform and what remains when continuous symmetries are broken. For now freely available at www.aimsciences.org/article/doi/... (but also at arXiv:2408.02119).

I am looking to hire a postdoc to work with me on fluid-structure interactions in complex and active fluids. Ideally the candidate will have a strong background in numerical/asymptotic analysis and fluid mechanics (complex fluids / LCs even better). www.mathjobs.org/jobs/list/26...

Active matter physics studies living beings as open, out of equilibrium, and emergent systems. In this perspective on plant morphogenesis, we show how such features arise from the basic hydromechanics of plant tissue and how to capture them in models. 🌱💧 Preprint 👇 arxiv.org/abs/2512.05554

O little town of Oxford, How still we see thee lie. But above thy deep and dreamless sleep, Complex thoughts go by. Still not convinced? Don't worry, you have all Christmas to 'mull' it over. Closes 12 January. Full details of the role: www.maths.ox.ac.uk/node/74844

Selfie, selfie, it's your call, who's the fairest of them all? Sam Howison, obviously. Except for one thing.

This week, the work we did as part of my research internship at IBM is being presented at the MLxOR workshop at NeurIPS. We look at uncertainty quantification for GFlowNets using PCEs. See the poster below:

How much human hyperbole has been spent on job descriptions and advertisements? We're looking for two researchers in stochastic analysis. Details together with other vacancies: www.maths.ox.ac.uk/vacancies

This new #JRSocInterface Perspective, using #neuroscience as an example, argues for a new paradigm of holistic #mathematical modelling that attempts to incorporate the necessary complexity into models of biological systems: royalsocietypublishing.org/doi/10.1098/... @rnartallo.bsky.social

Way to go Chris!

The future of modelling

It is a great piece. Soft and filling.

It's funny how in space all intuition about basic stuff - like water - goes out the window

The coolest math object is now in space.

Our inaugural Regius Professor of Mathematics, Andrew Wiles, retires in 2026 (not that mathematicians ever truly retire) and we are looking for his successor, starting in October of that year. Full details: www.maths.ox.ac.uk/node/74751

Introducing Pluto, a small, hungry cat and, like all his fellow Aristocats, an optical superhero. Everyone wants to be a cat.

You never know who'll you meet round here. People working in functional analysis or probability, mathematical physicists, applied mathematicians trying to model our environment, to name just a few. All of us hanging out in the same building. Come and join us: www.maths.ox.ac.uk/vacancies

How fast do plants actually grow? And which growth processes matter most for organ size? We dived into 176 papers, extracted and re-analyzed the data so you don’t have to! nph.onlinelibrary.wiley.com/doi/10.1111/... @newphyt.bsky.social @virajalim.bsky.social @elvisbranchini.bsky.social

🚨PREPRINT Coarse-graining diffusions with discrete-state approximations is an easy and effective way to build stochastic models from observed trajectories, but how valid is this approximation? arxiv.org/pdf/2511.05366 We focus on this problem, with an emphasis on the nonequilibrium steady-state.

These will go quickly - if you can join me on 3rd Dec in London, then grab a free ticket quickly.

A new paper with Bogdan Georgiev, Javier Gomez-Serrano, and Adam Zsolt Wagner: "Mathematical exploration and discovery at scale" arxiv.org/abs/2511.02864. Further discussion is at terrytao.wordpress.com/2025/11/05/m...

If it can cook potatoes, it can cook you!

Do you take your work home with you? It's kinda hard to avoid if you are a mathematician. The maths just follows you wherever you go. Sam Howison prepares vegetables.

Now published in Phys. Rev. E doi.org/10.1103/5l56...

Modelling bulk mechanical effects in a planar cellular monolayer arxiv.org/abs/2505.23935

New paper!💡 Amir Ohad developed this nifty setup to measure weak forces generated by freely moving plants, based on the deflection of a pendulum (straw from the cafeteria 😎), which does not require any tethering of the plant: academic.oup.com/jxb/advance-... Plant-obstacle interactions here we come!