We're not the only ones presenting at FENS, make sure to check out the amazing research from 𝗩𝗲𝗴𝗮𝗿𝗱 𝗙𝗶𝘀𝗸𝘂𝗺 & 𝗜𝗼𝗻𝗻𝗮 𝗦𝗮𝗻𝗱𝘃𝗶𝗴 at Poster PS-06-09PM-267, presenting in the afternoon poster session on 09.07.26 from 14:00 – 17:30 (abstract number 4487).

ISSCR 2026 is nearly here! Meet 3Brain and discover how CorePlate™‑enabled HD‑MEA enables scalable, high‑resolution electrophysiology for iPSC‑derived neurons and organoids. Let’s connect and explore how to unlock deeper functional insights from your in vitro models. #3Brain #HDMEA #ISSCR2026

𝗪𝗲’𝗿𝗲 𝗵𝗲𝗮𝗱𝗶𝗻𝗴 𝘁𝗼 𝗙𝗘𝗡𝗦𝟮𝟬𝟮𝟲! Visit 3Brain to explore our CorePlate™-enabled HD-MEA platforms for high-resolution, label-free recordings in iPSC neurons, organoids & brain slices. Let’s connect on neural circuits, development & disease! #3Brain #HDMEA #FENS2026 #BrainOrganoids #InVitroModels

Excited to join #DNM26, the Dutch Neuroscience Meeting! Join us to discover how 3Brain’s CorePlate™ HD-MEA captures high‑res, label‑free activity from iPSC neurons, organoids & brain slices. #3Brain #DNM26 #DevelopmentalNeurobiology #HDMEA #Electrophysiology #Organoids

Excited to attend ESTIV 2026! We’ll showcase how CorePlate™ HD-MEA enables high‑res, label‑free functional screening in advanced in vitro models like iPSC neurons & 3D cultures—driving next‑gen toxicology & NAMs. Working in neurotox or in vitro systems? Let’s connect! #3Brain #HDMEA #ESTIV2026

Excited to be at #BACELL2026! Join us exploring 3D cell models & organoids. Find out how CorePlate™-enabled 3D HD-MEAs reveal true functional insights from organoids & assembloids while preserving viability. #3Brain #HDMEA #BACELL3D #Organoids #3DCellCulture #Electrophysiology #DrugDiscovery

𝗢𝗻𝗲 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺. 𝟵𝟲 𝗪𝗲𝗹𝗹𝘀 𝗼𝗳 𝗣𝗼𝘀𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆. Few electrodes per well were once standard. Not anymore. Downsampling our 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟮𝟰𝗪 (1,024 electrodes) to low-density MEA levels showed it clearly: more electrodes = less variability, cleaner dose-response, fewer repeats, faster decisions. #HDMEA #3Brain

𝗪𝗲’𝗹𝗹 𝘀𝗼𝗼𝗻 𝗯𝗲 𝗮𝘁𝘁𝗲𝗻𝗱𝗶𝗻𝗴 𝘁𝗵𝗲 𝗦𝘄𝗶𝘀𝘀 𝟯𝗥𝘀 𝗗𝗮𝘆 𝟮𝟬𝟮𝟲 At 3Brain, we support 3R-driven neuroscience with CorePlate™ HD-MEA tech, enabling functional readouts of in vitro neuronal & cardiac models to reduce animal use and boost translational value. Come and say hi to Matthew Mullins! #Swiss3RsDay #HDMEA

Exploring drug screening with 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗗𝗲𝗹𝘁𝗮 & 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟮𝟰𝗪! We characterized a primary rat neuron dose-response under glutamatergic inhibition. High SNR from 1,024 electrodes/well gave tight error bars, revealing network activity shifts. #3Brain #HDMEA #HighThroughputScreening

𝗟𝗮𝘀𝘁 𝗱𝗮𝘆 𝗮𝘁 𝗠𝗣𝗦 𝗪𝗼𝗿𝗹𝗱 𝗦𝘂𝗺𝗺𝗶𝘁 𝟮𝟬𝟮𝟲! Come find Antonella Di Bello & Brook Sweeten at 𝗕𝗼𝗼𝘁𝗵 𝟰𝟬𝟰. Let's talk about how the 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝗛𝗗-𝗠𝗘𝗔 𝗽𝗹𝗮𝘁𝗳𝗼𝗿𝗺𝘀 deliver high-res, label-free functional readouts for your neuronal models: co-cultures, vascularized brain organoids, and beyond. Come say hi! 👋

𝗢𝗻𝗲 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺. 𝟵𝟲 𝗪𝗲𝗹𝗹𝘀 𝗼𝗳 𝗣𝗼𝘀𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆. Neuronal spikes. Network dynamics. Brain organoid field potentials. Cardiac waveforms. 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗗𝗲𝗹𝘁𝗮 + 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ captures them all -simultaneously across every well & electrode. Stay tuned for our NBQX & AP5 screening example on Rat Primary Hippocampal Cells.

𝗠𝗣𝗦 𝗪𝗼𝗿𝗹𝗱 𝗦𝘂𝗺𝗺𝗶𝘁 𝟮𝟬𝟮𝟲 𝗶𝘀 𝗮𝗹𝗺𝗼𝘀𝘁 𝗵𝗲𝗿𝗲! Join 3Brain to meet researchers advancing microphysiological systems. Our CorePlate™ HD-MEA platforms give a high-res, label-free window into neuronal activity — from co-cultures to vascularized brain organoids. Find us at booth 404 or posters 317 & 319!

RECI 2026 is almost here! Join the 3Brain team to talk ion channels in neuronal cultures & organoids. Our CorePlate™ HD-MEA platforms give label-free access to spiking activity in primary & iPSC models. Catch Sercan Deniz's talk or visit our booth! #Neuroscience #Electrophysiology #3brain #HDMEA

Excited to see this work move from preprint to publication in Science Advances! The study from Wu et al. (Yang group) delivers an important advance in how we investigate neuroimmune interactions in human brain organoids and assembloids and its affect on neuronal function!

𝗢𝗻𝗲 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺. 𝟵𝟲 𝗪𝗲𝗹𝗹𝘀 𝗼𝗳 𝗣𝗼𝘀𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆. 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗗𝗲𝗹𝘁𝗮 with 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟮𝟰 & 𝟵𝟲𝗪 scales with your biology — from primary & iPSC-derived neurons and cardiac cultures to spheroids and brain organoids. Simultaneous recording of every well & electrode = faster results, no quality trade-off. Stay tuned!

𝗧𝗵𝗲 𝗜𝗡𝗧𝗘𝗥𝗣𝗛𝗘𝗫 𝗝𝗮𝗽𝗮𝗻 𝟮𝟬𝟮𝟲 𝗰𝗼𝗻𝗳𝗲𝗿𝗲𝗻𝗰𝗲 𝗶𝘀 𝗷𝘂𝘀𝘁 𝗮𝗿𝗼𝘂𝗻𝗱 𝘁𝗵𝗲 𝗰𝗼𝗿𝗻𝗲𝗿! As pharma moves toward biologics & human-relevant models, functional readouts matter more than ever. 3Brain's CorePlate™-enabled HD-MEA platforms deliver scalable, label-free insights into neuronal & cardiac activity. See you in Tokyo!

𝗢𝗻𝗲 𝗽𝗹𝗮𝘁𝗳𝗼𝗿𝗺. 𝟵𝟲 𝘄𝗲𝗹𝗹𝘀 𝗼𝗳 𝗽𝗼𝘀𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆. Meet the 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ Multi-well series - featuring the world's first 96-well HD-MEA 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟵𝟲𝗪 and 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟮𝟰𝗪. With 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗗𝗲𝗹𝘁𝗮, progress from functional studies to high-throughput screening on a single platform. Next up: the cell models driving it.

𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝘀 𝗶𝗻 𝗖𝗲𝗹𝗹‐𝗯𝗮𝘀𝗲𝗱 𝗦𝗰𝗿𝗲𝗲𝗻𝗶𝗻𝗴 2026 kicks off tomorrow in Gothenburg! Find us at booth #𝟰 or catch our poster with 𝗔𝘅𝗼𝗹 𝗕𝗶𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲 presented by 𝗦𝗲𝗿𝗰𝗮𝗻 𝗗𝗲𝗻𝗶𝘇 — see how CorePlate™ HD-MEA is bridging complex in vitro biology with robust functional insights. See you there! #3Brain #ELRIG #HDMEA #iPSC

𝗢𝗻𝗲 𝗣𝗹𝗮𝘁𝗳𝗼𝗿𝗺. 𝟵𝟲 𝗪𝗲𝗹𝗹𝘀 𝗼𝗳 𝗣𝗼𝘀𝘀𝗶𝗯𝗶𝗹𝗶𝘁𝘆. The 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗗𝗲𝗹𝘁𝗮 captures functional activity across 24,576 electrodes simultaneously with no trade-off between detail and speed. High-throughput screening of neuronal & cardiac cells, high-resolution insights at scale. More platform features coming soon.

Testing neuromodulation tech like MENPs is tough, as many 𝘪𝘯 𝘷𝘪𝘵𝘳𝘰/𝘦𝘹 𝘷𝘪𝘷𝘰 models lack true human complexity. New work by Eggert et al. used CorePlate™ to show spiking & field potential activity in human brain slice cultures for an ethical, human‑relevant model to test neuromodulation technologies.

We're at the 𝗦𝘁𝗮𝗻𝗳𝗼𝗿𝗱 𝗗𝗿𝘂𝗴 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗦𝘆𝗺𝗽𝗼𝘀𝗶𝘂𝗺 (SDDS 2026)! Stop by and meet Amber Jolly to talk HD-MEA technology for drug discovery - from iPSC-derived networks to 3D organoids, CorePlate™ delivers high-throughput functional insights in formats up to 96-well. See you at Stanford! #SDDS2026 #HTS

We're sponsoring 𝗡𝗘𝗨𝗥𝗢𝗡𝗨𝗦 𝗜𝗕𝗥𝗢-𝗣𝗘𝗥𝗖 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲 𝗙𝗼𝗿𝘂𝗺 in Kraków! Come see how our CorePlate™ HD-MEA platforms from single to 96-well bridge the gap between complex biological models and functional insights. Meet Elisa Monz & Albert Steiner to talk about electrophysiology workflows. See you there!

New work from 𝗗𝘂𝗱𝗮 et al., 𝗣𝘂𝗹𝗹𝗲𝗿& 𝗚𝗿𝗲𝘀𝗰𝗵𝗻𝗲𝗿 shows displaced RGCs are fully integrated in the visual circuit. Using CorePlate™ HD‑MEAs, they mapped dRGC spatial + functional properties, revealing displaced sONα cells fill mosaic gaps and share the same role. Huge thanks to the team! #HDMEA #Retina

We're at the Membrane Physiology Symposium 2026 in Napa Valley! Meet 𝗔𝗺𝗯𝗲𝗿 𝗝𝗼𝗹𝗹𝘆 at the Meritage Resort & Spa to see how CorePlate™ HD-MEA platforms deliver high-resolution, label-free functional insights for neuronal and cardiac research. #3Brain #MembranePhysiology #IonChannels #Electrophysiology

How do cortical and hippocampal neurons differ in their baseline firing and drug response? Our latest application note uses 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ 𝟲𝗪 and 𝗛𝘆𝗽𝗲𝗿𝗖𝗔𝗠 𝗔𝗹𝗽𝗵𝗮 to functionally screen both side by side with 𝗖𝘆𝗰𝗹𝗼𝘁𝗵𝗶𝗮𝘇𝗶𝗱𝗲 (𝗖𝗧𝗭). Check it out: resources.3brain.com/f1/downloads... #HDMEA #Electrophysiology

Great to see this ALS research move from preprint to publication. The newly published work from Fiskum et al. In 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 𝗡𝗲𝘂𝗿𝗼𝘀𝗰𝗶𝗲𝗻𝗰𝗲 offers powerful new insight into how motor neurons are affected in ALS. Congratulations to 𝗩𝗲𝗴𝗮𝗿𝗱 𝗙𝗶𝘀𝗸𝘂𝗺 and the 𝗜𝗼𝗮𝗻𝗻𝗮 𝗦𝗮𝗻𝗱𝘃𝗶𝗴 lab! #ALS #HDMEA #iPSC

We're Heading to the French Alps for the 𝟵𝘁𝗵 𝗖𝗲𝗿𝗲𝗯𝗲𝗹𝗹𝘂𝗺 𝗗𝗮𝘆𝘀 to join world-leading researchers at the CNRS Paul Langevin Center in 𝗔𝘂𝘀𝘀𝗼𝗶𝘀 from 𝗠𝗮𝗿𝗰𝗵 𝟮𝟲𝘁𝗵 – 𝟮𝟵𝘁𝗵. If you’re interested in exploring the functional activity of your cerebellar slices, be sure to connect with us. #3Brain #Cerebellum

Visit 3Brain (Mar 22–25, San Diego) to see how our CorePlate™ HD-MEA platforms turn organoids and spheroids into actionable data. Accelerate your neuro/cardiotoxiology research with functional insights from our BioCAM and HyperCAM Delta. #2026SOT #ToxExpo #3Brain

New organoid research shows SMA affects far more than motor neurons, revealing widespread CNS disruptions. Using CorePlate™ HD MEAs, researchers found reduced activity, glutamate hyperexcitability, and showed early ASO treatment can rescue function. Huge thanks to the team! #iPSC #HDMEA #3Brain

Celebrating our 2025 MGA winner, Noelia Antón Bolaños! Her work pushes functional neuroscience forward and holds real potential for human health. Read her project story and interview here (onlylinks.cc/OevP) and stay tuned for 2026 MGA applications!

𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝗯𝗮𝗹𝗮𝗻𝗰𝗲 𝗲𝘅𝗰𝗶𝘁𝗮𝘁𝗶𝗼𝗻 & 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝗶𝗼𝗻? A new study by 𝗖𝗿𝗼𝗰𝗰𝗼 et al. (𝗖𝗿𝗲𝗺𝗶𝘀𝗶 𝗟𝗮𝗯) uses stem cell-derived DT/VT populations on CorePlate™ to map how E/I ratios shape network dynamics. Vital research for understanding neurodevelopmental disorders. #3Brain #HDMEA #electrophysiology

Excited to join pharma & biotech leaders at ENIF. At 3Brain, we’re pushing HD‑MEA innovation, from the first commercially available HD‑MEA, to CorePlate™ 3D & our new 96‑well platform. Partnering with pharma drives our breakthroughs. If you’re at ENIF, come say hi and talk HD‑MEA innovation.

Join our Lunch & Learn on 3Brain's CorePlate™ HD-MEAs: network activity with single-cell precision in neuronal and cardiac cultures. Explore maturation, disease models, and compound effects. Single-well to 96-well plus CorePlate™ 3D for organoids. Tues, Mar 3, 12-1 PM, Gladstone. Lunch provided.

𝗕𝗹𝗼𝗰𝗸 et al. from the 𝗚𝗿𝗲𝘀𝗰𝗵𝗻𝗲𝗿 𝗹𝗮𝗯 utilised CorePlate™ HD-MEAs to show avian retinas feature saltatory conduction. Tracking spikes propagation along the axons, they found spikes can travel 4x faster than in rodents! #Neuroscience #Electrophysiology #HDMEA #Retina

New research from the 𝗚𝗼𝗹𝗹𝗶𝘀𝗰𝗵 𝗟𝗮𝗯 uses computational modelling to predict RGCs responses across species with data collected from CorePlate™ enabled HD-MEAs. The findings: Divisive & Subtractive models beat feedback, Divisive = best for fast kinetics, Subtractive = best for slow signals. #retina

𝗙𝗼𝗿𝗯𝗲𝗿𝗴𝗲𝗿, 𝗞𝗿𝗮𝗴𝗲𝗹𝘂𝗻𝗱 & 𝘁𝗵𝗲 𝗞𝗶𝗿𝘀𝗰𝗵𝘀𝘁𝗲𝗶𝗻 lab have developed a protocol which shows how to use CorePlate™ enabled 3D HD-MEAs (4,096 electrodes) to map how tumors disrupt brain networks. By tracking activity trajectories (CATs), they revealed lost functional connectivity in glioma models. #HDMEA #Cancer

WORD 2026 - This year, we presented a scientific poster on CorePlate™ recordings of hippocampal organoids and their responses to various neuroactive compounds. A huge thank‑you to everyone who visited our booth, discussed their work, and shared new ideas! #WORD2026 #BrainOrganoids #HDMEA #Ephys

Meet us at the Science & Tech Expo on Feb 10 at the Alexandria Center, Stanford Research Park! Discover how CorePlate™ HD‑MEAs enable deeper functional insights across neuronal & cardiac models. Plus free desserts, coffee & smoothies. Come say hi!

New research from 𝗜𝗮𝗻𝗻𝗲𝗹𝗹𝗼 & 𝗖𝗶𝗮𝗺𝗽𝗶 (𝗔𝗺𝗮𝘁𝗼 group) shows how cultured neurons can be used for Biological Reservoir Computing. By encoding images into electrical patterns via HD-MEAs, they’ve enabled biological networks to perform pattern recognition. Check out the paper here: arxiv.org/abs/2510.05637

How do we better model cholinergic pathways? By building human brain assembloids. Using CorePlate™ 3D electrodes, the 𝗟𝗶𝘂 𝗟𝗮𝗯 recorded high-res data from hnbM-cortical projections, even transplanting them into mice to establish human-derived pathways. #3Brain #iPSC #HDMEA #Organoids #Assembloids

𝗭𝗮𝗽𝗳𝗲 et al. used CorePlate™ to track the center of mass of current in the hippocampus. It’s not just data, it’s a way to see hidden synaptic interactions in high-res. As a bonus, the current source density (CSD) graphics are stunning! #Electrophysiology #HDMEA #Hippocampus #NeuralCircuits

𝗠𝗶𝗰𝗿𝗼𝗴𝗹𝗶𝗮 𝗶𝗻 𝘁𝗵𝗲 𝗰𝗶𝗿𝗰𝘂𝗶𝘁! 𝗪𝘂 et al. show that adding human microglia to organoids and assembloids shapes circuit formation and activity, and that CorePlate™ HD-MEAs enabled them to reveal functional midbrain–striatal connectivity and hyperactivity in ASD-mutant assembloids.

𝗪𝗵𝗲𝗻 𝗮𝗻 𝗜𝗺𝗺𝘂𝗻𝗲 𝗚𝗲𝗻𝗲 𝗥𝗲𝘄𝗿𝗶𝘁𝗲𝘀 𝗕𝗿𝗮𝗶𝗻 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁: 𝗗𝗲𝗺𝗲𝗻𝗲𝗴𝗼 et al. showed that hyperactive CXCR4 (linked to WHIM syndrome) disrupts cerebellar development and motor function, independent of infection. Using CorePlate™ HD-MEAs, researchers revealed circuit-level defects and a path to early intervention.

How DNMT3A mutations reshape neural circuits. New work shows TBRS-associated DNMT3A mutations disrupt human cortical interneuron development, driving GABAergic hyperactivity and abnormal network bursting, revealed using CorePlate™ enabled HD-MEAs. #Neuroscience #3Brain #Electrophysiology #HDMEA

Reflecting on 2025, we are reminded that behind every data point is a dedicated researcher. From our MGA applicants to the energy of our global workshops, your passion is our inspiration. Thank you for your contributions to neuroscience. Wishing you rest, joy, and a Merry Christmas. buff.ly/NqmRcK4

A look back at the Assembloids & Complex Cell-Cell Interactions across Tissues & Organs meeting at CSHL. A fantastic conference exploring advances in assembloid research, with a workshop hosted by us to show how CorePlate™ enabled HD-MEA is helping functionally characterise assembloids.

At CSHL Assembloids? Our workshop is today, 𝗗𝗲𝗰 𝟵𝘁𝗵 𝗮𝘁 𝟭𝟮:𝟯𝟬𝗽𝗺! Join us for live experiments, software demos, and hands-on tools to assess organoid and assembloid activity. Stop by our booth to connect or register online for this interactive session: www.3brain.com/events/cshl-25

That’s a wrap on our “Recording Organoids with CorePlate™” workshop! From hands-on recordings in the Discovery Laboratory to BrainWave 6 analysis, the collaboration was inspiring. Huge thanks to all participants for the engagement—we are excited to see where your research goes next!

𝗗𝗲𝗰𝗼𝗱𝗶𝗻𝗴 𝘁𝗵𝗲 𝗶𝗱𝗲𝗻𝘁𝗶𝘁𝗶𝗲𝘀 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗮𝘁 𝘀𝗰𝗮𝗹𝗲 𝗚𝗶𝗿𝗮𝘂𝗱 𝗲𝘁 𝗮𝗹. show how 𝗖𝗼𝗿𝗲𝗣𝗹𝗮𝘁𝗲™ HD-MEA recordings, combined with their 𝗦𝗽𝗶𝗸𝗲𝗠𝗔𝗣 pipeline, can identify neurons without prior labels, validated through viral and optogenetic methods. A remarkable advance for large-scale electrophysiology.

Human striatal progenitors can rebuild broken brain circuits. 𝗦𝗰𝗮𝗿𝗮𝗺𝘂𝘇𝘇𝗮 et al. Recently showed that transplanted human striatal progenitors in an HD rodent model survive, differentiate, and integrate, with CorePlate™ HD-MEA recordings revealing some very interesting graft activity!