It's an exciting day for #Fiji users! Now read and write @zarr.dev v3 and #OMEZarr v0.5. Don't want a million tiny files in your #zarr? Shard that sucker! Read the details here forum.image.sc/t/fiji-can-r...

posting this Classic over here in honor of the big man himself. adios bitch

Incredible timelapse of the Aurora, captured by astronaut Sophie Adenot

elections, thank fuck, have consequences

Under Lula, Amazon deforestation falls to lowest level in a decade https://aje.news/4aer73

Shallow-water (but not deep-water) octopuses have mutations producing high-fidelity ribosomes that make a lot fewer protein aggregates of the type involved in Parkinson's, Alzheimer's, ALS & Huntington's Disease. It *may not* be a coincidence that this evolved in large-brained cephalopods.

If you are a researcher that uses slop machines to create figures for your talk, you are embarassing yourself

I'll summarize this: Mamdani asked NYers to keep air conditioning at 78 degrees. A wave criticism hit online. A MSNBC broadcast pointed out the US Department of Energy recommends that 78 degree figure. Immediately after, the US Department of Energy deleted 6,000 web pages related to energy saving.

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Here is yet one more example. Miller's silhouette is similar to the first Palmolive bottle, whereas he would benefit from having more padding and extension, which would create the second Palmolive bottle.

«The biases do not disappear; they get encoded into the model and then laundered into outputs that feel objective because they are numerical. Replacing one prestige filter with another that is harder to see or challenge is not progress toward equity in science; it’s the opposite. »

One understressed item about various AI tools is what providers are getting out of your submissions- is your text being used for something? Who’s to say? Is it going into some model? Is a person leafing through it??? I see no reason to trust anyone on this stuff

Don't use slop. Someone's trying to make money out of you and your colleagues and your friends. Do yourself a favor and read 100% human-crated content in @prelights.bsky.social Upload preprints. Read preprints. Cite preprints. Fuck AI 🧪

This is why we love #CalciumSignaling Look how mechanical damage triggers long range Ca2+ waves in this plant !! By @annalisabellandi.bsky.social, who is now around here ;) Full www.science.org/doi/10.1126/... @science.org #microscopy #cell #mechanobiology 🧪🔬

As a scientist, there are so many issues with this. Besides the simple technical things (e.g. no baseline or comparative models), the critical one is that there are so many dimensions of impact that any single metric is bound to be horrible and biased. This is clear already in their analysis.

HAHAHAhaha! they're making the world's biggest synthetic scum pond!!! The coating is a polyurea used inside pipes. It gels in about 3 seconds, making it non self-leveling. The texture is like an orange peel, the perfect substrate for biofilms. www.nytimes.com/2026/05/19/u...

Janelia’s decision to wind down its mouse work to focus on the Danionella fish is a “bold move” that caught some by surprise, researchers say. #neuroskyence By @callimcflurry.bsky.social www.thetransmitter.org/community/ex...

'Storm in the Mountains', Albert Bierstadt, oil on canvas, 1870.

Q.E.D. 🤦‍♀️🇨🇭🤦‍♂️

Rewild the reflecting pool. Make it a wetland bird sanctuary. Fill it with endangered salamanders. Foster the fermentation of whatever it is that makes swamp gas. Put up little signs welcoming fairies. Let stray senators wander in never to be seen again. Elect a bog witch. Make America Moss Again

Fantastic video on this beautiful work of Chen-Hui Chen's team!

He kept coming back, repeatedly (in the way AI often loops) to this idea of AI (specifically Claude) representing "a position without an address", and it became increasingly clear to me that there was some odd mystification happening. Of course LLM products have an address. It's a corporate address.

When did animel started to move? The earliest animals were immobile, but sometimes, probably in the late Ediacaran, there was motion, and the traces these early animals left behind are how we can trace that. ⚒️🧪 Link: https://www.pnas.org/doi/10.1073/pnas.2609730123​

Why I 🧡 the web: TinyWind is a "pixel pirate sailing game" with real wind physics. Even has a leaderboard. tinywind.io #games #pirates #javascript

We did it with the post-war settlement, the 30 glorious years when we built the welfare state, regulated polluters and bosses, and kicked off the civil rights movement. We did it then, and we can do it again. We must. All things serve the beams. eof/

Support activist groups like the Electronic Frontier Foundation, the digital rights group I've been at for the past 25 years: supporters.eff.org/donate/join-... 84/

What I have for you is *political* advice. To restore the beams and beat back entropy again, we need a better *system*, not more virtuous individuals. If you feel - as I do - that "the world has moved on," then to wrench it back, you will have to join a *polity*. 83/

Robin's answer: the foundation that all these otherwise disparate views share is that some people are born to rule, while others are born to be ruled over. When these lesser people are elevated to positions of power, their inferiority creates a system of misrule, by which we all suffer. 42/

And the foundation - the Dark Tower upon which all the beams converged- was antitrust enforcement. 36/

🤭

No one with experience doing that would just wave their hands and say ROBOTS ✌️✌️. For some fields of science the market is big enough to build new ROBOT equipment. But ask Thorlabs or all the neuro startups about this. Mostly, your new pioneering equipment will never sell enough

New alien friend in the echinox lab: the basket star Astrospartus mediterraneus. A truly bizarre fractal body plan, but sooo beautiful 🤩🥹

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

We are implementing a similar policy at @arxiv.bsky.social. If there is incontrovertible evidence of LLM slop in a paper, this means the authors did not take the time to read the LLM output and we can't trust anything else in the paper. Penalty is 1 year ban from arXiv followed by...

In evolutionary biology, we call this conflation of proximate and ultimate explanations. Kind of argumentation like "this bird does not sing because it helps to attract a mate, he just has high testosterone levels."

HazeMatching has been accepted to #CVPR2026 (Findings)! @cvprconference.bsky.social 🎉🎉 What if widefield microscopes could produce confocal-quality images? We introduce a Guided Conditional Flow Matching (CFM) framework that does exactly that. Learn more here: www.linkedin.com/feed/update/...

Interesting! doi.org/10.1242/dmm.... "Debates about animal research & alternatives are often framed as a contest between old and new approaches. This framing is both misleading and counterproductive. In practice, modern biomedical research is increasingly characterised by methodological pluralism"

Altair Direct View OPM Preprint! We built a simplified direct-view oblique-plane microscope for imaging big, optically accessible specimens with a single-objective light-sheet geometry. Delivers... • ~5.4 mm field of view • ~2.6 μm, ~3.4 μm, and ~17.8 μm resolution in X/Y/Z

A paper is not just its underlying data but also the narrative the authors have decided to use. How authors interpret and explain their results is important. Different readers can then read and interpret differently, but that initial narrative is relevant.

Thank you @dvonwangenheim.bsky.social @the.3i.social for this awesome demo of your spinning disc system for #rootimaging

Meet MagLuc: a magnetically-controlled luminescent protein. This is a foundational tool for remote control of biological processes, also known as "magnetogenetics". Can you tell when the magnetic field turns on and off? From @mariaingaramo.bsky.social and the team at @nonfictionlabs.bsky.social

What should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪

Alternatively, natural behaviors might elicit reliable neural signatures in high-level visual and motor regions which contain invariant representations, and involve correlated sensory and motor information that leads to apparent mixing. 5/8

when we mourn le guin, we mourn one of our greatest writers & thinkers. but we also mourn one of our all-time greatest haters

Roughly two weeks (until May 15th) left to apply and join our team! Bioimage Analyst: careers.humantechnopole.it/job/Bioimage... Rsearch Software Engineer: careers.humantechnopole.it/job/Research...

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

Excited to share the first study from the Morstein Lab on a new approach that enables selective editing, tagging, and visualization of mammalian lipids www.biorxiv.org/cgi/content/... #chembio #lipidtime @caltech.edu @caltechcce.bsky.social @harayamajrlab.bsky.social @logan-tenney.bsky.social

This looks absolutely amazing. Rats composing long action sequences out of short ones. mPFC constructing the long sequence on the fly. Reusing the primitive representations but composing them with progression along the composite. One of the most impressive things I have ever seen a rodent do.

Nature research paper: Astrocytes connect specific brain regions through plastic networks go.nature.com/4eBe8fV

We are still accepting applications for an image analyst within the Optical Imaging Core at Van Andel Institute. If you know anyone that is looking for a career in image analysis, please encourage them to apply! vai.wd1.myworkdayjobs.com/en-US/VAICar...