We live in a country where the two most dynamic, charismatic, eloquent politicians of this century have the first names Barack and Zohran. This is what bothers the white supremacists so much.

#NoKings at San Francisco’s ocean beach — protesters joined to form a human banner saying Trump must go now.

Omg! Huge shoutout to San Francisco, CA! Ocean Beach, you crushed it! 🌊

Recently amplified gene arrays are a super interesting phenomenon, but many still resist our attempts to assemble them. @dantipov.bsky.social has developed a new method (Trivial Tangle Traverser) that resolves assembly graph tangles caused by such sequences (1/4) www.biorxiv.org/content/10.6...

Thank you to Pete Hegseth for vividly illustrating why it's so important to support independent media organization's like TPM during our annual membership drive. talkingpointsmemo.com/edblog/state...

Tonight's a good night for every new org to confirm that the DOJ covered up accusations of child rape against the man currently speaking.

the Epstein files are really devastating because they remind me of how many girls and women miss out on professional opportunities, mentorship and careers because of how many powerful, rich and influential men only view girls and women — and interactions with them — through the lens of sex

Lots of correspondence between Robert Trivers and Jeffrey Epstein mentioning money and a predatory view of women 🤮https://www.justice.gov/epstein

"If you are a contract employee, I absolutely need your W-9. And that means your ACTUAL LEGAL NAME. I’m getting too many forms in here with names like 'A. Concerned Citizen' and 'Fight D. Power."

I'm calling bullshit on the media narrative that Trump is "pivoting" and "deescalating" on his ICE raids. The threshold is this: As long as the military occupations and the treatment of US cities as enemy territory continue, there's no pivot. ICE out. 1/ (New piece) newrepublic.com/article/2057...

Incredible interview. In awe of this woman's bravery. A true patriot. www.cnn.com/2026/01/27/u...

Defenceless under the night Our world in stupor lies; Yet, dotted everywhere, Ironic points of light Flash out wherever the Just Exchange their messages: May I, composed like them Of Eros and of dust, Beleaguered by the same Negation and despair, Show an affirming flame. — W.H. Auden, Sept. 1, 1939

Q: Wait. How about fucks? Do you have any of those to give? A: Great question. Alas, none of those, either. To be clear, we give neither a shit nor a fuck about your opinion on our behavior.

Consider donating to support families and students impacted by the ICE activity in Minneapolis gofund.me/53ddce08e

Not to be too hyperbolic but I feel like price discrimination at this granular a level, if done at scale, kinda takes a sledgehammer to some of the fundamentals of microeconomics. www.marketplace.org/story/2026/0...

Consider donating to support families and students impacted by the ICE activity in Minneapolis gofund.me/53ddce08e

Wow! 167.2 Gb HiFi yield from a PacBio SMRT cell🎉 Are we getting close the record? This run was for the “Genome of Sweden” project, where we're building a national reference dataset from 10 year old biobanked DNA samples🧬🧪

Holy shit moment. Good statement. The corrupt authoritarians and oligarchs are at the gates. There’s no alternative to fierce resistance and putting down their lawless crusade against the American Republic. x.com/federalreser...

Hey people! My son's science fair project is about how people visualize things when they read. It's very short and he'd appreciate it if you could fill it out, and share for more responses! (info: 'print books' also includes ebooks) Thank you! ☺️ docs.google.com/forms/d/e/1F...

Sequencing Instrumrnt Outlook 2026 My observations & predictions on sequencing instrument companies 🧬🖥️ omicsomics.blogspot.com/2026/01/sequ...

There is always so much more to learn about Albert Einstein as a person. Such a good guy. Hopefully this link will allow sharing of this fondly-written piece about his life in Princeton. www.theatlantic.com/culture/2026...

New year new office layout new plants 😍🤩

I love this concept, New York City as a “great processing station of Americanization.” I’m proud and lucky that my Jewish ancestors went through that processing station 100 years ago.

“Most of us live off Hope” Ever true 💔

Starting //// going

disturbing look at how Roblox prioritizes growth for investors vs safety for their users/concerns of their parents.Thanks for covering this @caseynewton.bsky.social and @kevinroose.com www.nytimes.com/2025/11/21/p...

Subtle differences in repeat motifs can cause drastic diff in disease onset: using @pacbio.bsky.social PureTarget amp-free identifies non-canonical repeats and its ratio assoc. with disease onset for Spinocerebellar ataxia type 10 (SCA10) www.neurology.org/doi/full/10....

It's not a foolproof plan but every political debate from now on should be a Normal Guy competition. Ask them to describe grocery shopping in detail. Talk about what it's like to have a friend

One of my earliest moments of radicalization was in 2005 when Larry Summers said that women biologically have less aptitude for science than men. Following that, scores of equally unimpressive people wrote pieces trying to explain or justify his remarks, when they should have called for his removal.

I was a grad student at Harvard when Larry Summers said the reason women were underrepresented in science was natural aptitude. Love to see this news.

Something absolutely perfect about Larry Summers riffing about the scourge of woke cancel culture being unfair to predatory men in a friendly email to his pal JEFFREY EPSTEIN.

Rep. Adelita Grijalva (D-AZ) is FINALLY sworn in and is now officially a member of Congress.

It's been 50 days since Adelita Grijalva was elected by the people of Arizona's seventh congressional district to represent them in Congress. She'll finally be sworn-in today.

BIG NEWS: Congresswoman-elect Adelita Grijalva will finally be sworn in as a member of Congress tomorrow. She is likely to be the 218th vote on the Epstein discharge petition, which would force a full vote to release the Epstein files in their entirety.

This is nearly at 47k signatures, by the way. Join us.

Oh look, we’re already on it!

I think democratic voters need to wage a pressure campaign to get rid of speaker @schumer.senate.gov talkingpointsmemo.com/edblog/with-...

BREAKING: Colorado voters approved a ballot measure that would raise state income taxes on higher-earning households to fund free meals for all public school students. Follow AP for live updates.

This 👇👇👇

I do think yesterday’s results reinforced the dynamic that while much of the American leadership class is chickenshit, most of the electorate is not

If I were running the DNC, there would be Democratic Party sponsored food relief banks across the country right now that specifically welcomed anyone regardless of party affiliation. Along with the food, there could be voter registration and links to runforsomething.net

[The No Kings demonstrations] make clear that Donald Trump’s conquest of the American Republic is far from complete and is in fact unlikely to ultimately succeed.

The following is REAL footage from Portland, 2025. Viewer discretion is advised.

This is the correct response. Expose the MAGA narrative as a lie. Make MAGA look weird again.

I feel like this photo of masked, armed men pepper spraying a pastor protecting his community is going to be a defining picture of this moment in America for a long, long time.

@mollyschumer.bsky.social if the data is pre SPQR chemistry I would recommend fibertools. If it’s new data then you can use Jasmine from Pacbio, Andrew and I spent a fair amount of time looking at the Jasmine results and they look good. And it will all still work with downstream fibertools commands

Did you know? Revio & Vega include on-instrument 6mA calling for the Fiber-seq chromatin accessibility assay. Thanks to Fiber-seq expert @mrvollger.bsky.social for the thoughtful evaluation and recommendation. Reagents for the assay are also available from our friends at EpiCypher: bit.ly/42YwGQE