I'm super excited to announce the new PureTarget kits from @pacbio.bsky.social are out! We have a new carrier screening panel and updated repeat expansion panels plus variant calling software to support both. Press release - www.pacb.com/press_releas...

Doooooom is back! I’m going to be a panelist for Oral History Live! Roundtable with Boston Roller Derby. It’s the 20th anniversary of the league I helped found. It’s a virtual event, you can sign up here www.eventbrite.com/e/oral-histo...

Breaking News: A federal appeals court upheld a decision that temporarily halted agents from arresting and detaining L.A. immigrants without probable cause.

Quest Diagnostics launched a new test for ataxia using long-read sequencing based on the PacBio #PureTarget method. It can uncover hidden genetic causes of disease, including repeat expansions often missed by other tools. Details here: bit.ly/4fcu4DV #PacBio

Some exciting professional news: Athena Diagnostics, Inc. developed an LDT using PacBio's PureTarget technology (my product!!) and HiFi sequencing on the Revio, which improves Ataxia Diagnostics for some of the most challenging genes in the human genome. Read the press release here: lnkd.in/g-ec-ECq

🚨Federal judge orders DHS to limit “roving patrols” in Los Angeles. The judge finds that the evidence shows that DHS officers are racially profiling people to demand their papers, which all sides agree is illegal, and orders DHS to stop those unlawful practices.

10 days relief from indiscriminate terror www.nytimes.com/2025/07/11/u...

Harvard sociologist/polisci Theda Skocpol explains how the vast expansion of ICE in BBB may be Trump's secret weapon to overcome the barriers of federalism and complete his autocratic takeover of the American state. (History from Germany & Hungary in 20s/30s.) talkingpointsmemo.com/edblog/criti...

The Tea Party protests in April 2009 had about a third of a million people involved, and the political media treated it like a game changer for the Obama presidency. The No Kings rallies were AT LEAST ten times bigger than the Tea Party protests. Will the press keep pretending Trump is popular?

Ahead of tonight’s Angel City match, the club stands with the city of LA. Fans found these shirts at their seats and together with the players are showing that Los Angeles is for everyone ❤️ 📷: @angelcity.com

My favorite #Wisconsin #NoKings sign/flag from today. #wipolitics

So proud to be a part of this amazing morning. Location ocean beach San Francisco #nokings

Big turnout at #nokings in #sanmateoCA #nokingsprotest @50501movement.bsky.social @joshtpm.bsky.social @indivisible.org

Possible to start to tell a unified story: "Trump is personally too old, crazy, and confused to run things, so at any given time the question is which co-president is in charge. At first it was Musk, & we got the crazy chaotic DOGE era. Then Navarro: a trade war that crashed markets. Now Miller..."

Breaking: A federal judge halted President Trump’s deployment of California National Guard soldiers in Los Angeles, finding that he broke the law in ordering them to put down urban unrest without consulting Gov. Gavin Newsom. cal.news/4l4l7y9 📸 Ted Soqui

this should be unlocked www.wsj.com/us-news/prot...

Fake Images and Conspiracy Theories Swirl Around L.A. Protests www.nytimes.com/2025/06/10/t...

@joshtpm.bsky.social are you following this? If the clash between civilians and ICE escalates out of control anywhere, it will be in Los Angeles www.nytimes.com/2025/06/07/u...

Join ‪@sarahdoom.bsky.social‬ for a preview of our must-see #ESHG2025 activities: expert talks, live #HiFiSequencing demos, tech showcases, and more. Come see what it’s all about! #Genomics

Great poster presentation #ESHG2025 done by @sarahdoom.bsky.social on @pacbio.bsky.social PureTarget application 😃

ESHG has been really fun so far. Check out the PacBio satellite symposium tomorrow where I’ll be talking about what’s coming next with PureTarget. 14:15 in Amber 5-6. We’re about more than just the best party.

Here's the opening, folks. Good work for Durbin cracking it open. No ALS research cuts, you say? Oh dear.

A Path Forward to Save American Bio-Medical Research talkingpointsmemo.com/edblog/a-pat...

How much will it cost the Air Force to remove all the listening devices from Trump's pimpmobile plane?

Emily Farrow from Children’s Mercy Hospital is the first speaker on day 2 of @pacbio.bsky.social PRISM SF.

i often see things that make me say "this is the most Boston thing I have ever seen in my life" but i think this one might have swept them all

Remember the 6 men who forcibly removed Dr. Teresa Borrenphol from the Coeur d'Alene town hall? They’ve been arrested and charged! www.kivitv.com/news/six-men...

It's always wrong to vandalize personal property and that certainly includes Teslas, and also: your government is actively disappearing innocent people without due process, so, you know, that second one is taking up my empathetic bandwidth at the moment.

You should totally go talk to @jocelyne8.bsky.social but if you can't the poster is already on our website www.pacb.com/wp-content/u...

Happening now, @pacbio.bsky.social PureTarget poster presented by @jocelyne8.bsky.social at #ACMG poster #340. Learn about PureTarget for scalable #HiFi sequencing of native DNA #repeatexpansions #longreads

Learn more in our latest ACMG poster: www.pacb.com/wp-content/u...

Don't just take our word for it, companies like Athena Dx (a business of Quest Dx) are using PacBio PureTarget in their new Ataxia offering!

It's @pacbio.bsky.social fairy tale Friday! Once upon a time, you do lots of PCRs to screen different ataxia genes. Now with PureTarget, you can do 20 genes at once, get repeat lengths, repeat sequences, and even methylation patterns!

Happening now, @pacbio.bsky.social PureTarget poster presented by @jocelyne8.bsky.social at #ACMG poster #340. Learn about PureTarget for scalable #HiFi sequencing of native DNA #repeatexpansions #longreads

Happy Monday! Let's start this week with fairy tales! ONCE UPON A TIME extracting high molecular weight (HMW) DNA was difficult. But now, with @pacbio.bsky.social Nanobind extraction kits. you get HMW DNA in, and beautiful long reads -> genome assemblies out! 💫⭐🧪🧬 www.pacb.com/products-and...

I got laid off today, with the rest of 18F. 18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it. We made this website to tell our story: 18f.org

Huh, turns out you can't have private UNIDENTIFIED security assault and kidnap people because you don't like what they say at city hall Weird.

Consider donating to @acaciajustice.bsky.social who just lost their federal funding to provide legal representation to unaccompanied migrant kids. I just did. Read more here www.latimes.com/politics/sto...

Let’s get something clear. The GOP has the power to keep the government from shutting down in March. They control both chambers of Congress and the White House. If they can’t reach a budget deal within their own ranks, that completely on them. Dems: Don’t lift a finger to help them. Not one.

Did your Rep or Senator get rocked at a townhall last week over Elon's DOGE crime spree? Check out epic townhall rockage list and if they're not on it drop us a line so we can add them. talkingpointsmemo.com/edblog/ye-ol...

In light of everything happening, I wrote about how the KKK in the 1920s felt unstoppable, about the people that fought against them anyway, and about how fascism always fails. dansinker.com/posts/202…

To all my friends and colleagues in Germany, hoping the firewall holds against the far right in the election today. www.nytimes.com/2025/02/23/w...

I can’t think of more fertile ground for an organized resistance than massive layoffs of civil servants www.nytimes.com/2025/02/22/u...

Kudos to the school administrator who wrote this letter for making it clear to families what happened and who they should blame. This is the way to build a coalition--with a shared adversary and a reason to fight.

Introducing the PacBio Vega system – HiFi sequencing within reach. Come by our #LorneGenome2025 booth (#4) to learn more! #LorneGenome #Sequencing @pacbio.bsky.social

Trump Can’t Be Allowed to Control Almost Half Of New York State talkingpointsmemo.com/edblog/trump...

👀 looking at you, NYC “Absent the collaboration of blue cities, he cannot round up and deport millions of immigrants.” Time for Kathy Hochul to remove mayor Adams.

“We must especially beware of that small group of selfish men who would clip the wings of the American eagle in order to feather their own nests.” -FDR, 1941