I am sad to hear about this industrial disaster and tragedy. Just awful. www.opb.org/article/2026...

A wonderful opportunity!

On the other hand, there have been many deaths associated with refusing  vaccines.

ICE knows it's acting illegally and without authority to arrest in thousands of cases. The court records demonstrate this. It must stop. Now.

The Oregon Garden in Silverton is worth a visit. This beautiful flower made me wonder if that fuzzy orange bit is meant to look like a caterpillar to attract a pollinator.

Simple suggestion to improve the NIH grant review process: Release the summary statements of the "not discussed" after the meeting instead of up to 30 days later. Those reviews aren't being edited.

Interested in microbiology, immunology, and host-pathogen interactions? Come work with us! Our department at OHSU is opening a search for a new tenure-track faculty position. See the job advertisement for details. Please share within your networks! www.nature.com/naturecareer...

New work from @jcslab.bsky.social. Novel approach to measuring mycomembrane fluidity and dynamics. I like the comparison of species in Figure 2... Check it out! pubs.acs.org/doi/10.1021/...

The National Science Foundation is the main source of funding for basic sciences in the US. For decades, they have supported a scientific R&D ecosystem in the US that has been an engine of economic growth and competitive advantage. Destroying the agency is no less than an act of sabotage.

Super excited that our SEE-CITE photoaffinity labeling method is now out in @natchem.nature.com rdcu.be/ffBSC. Here we introduce a custom silyl ether cleavable linker between a diazirine photocrosslinker handle and molecules of interest to streamline site-of-labeling analysis for PAL chemoproteomics

Excited that our paper on enzymatic bromination of peptides is now online at ACS Chemical Biology! Led by Haley Bridge, we showed that the flavin-dependent halogenase RebH and its variants can be used for late-stage chemoenzymatic diversification of bioactive peptides: pubs.acs.org/doi/10.1021/...

Celebrating with my team at Oregon's gorgeous state park: Silver Falls. Yes, we hiked behind this waterfall!

"But much as Musk might want us to divert our eyes upward, something terrible is happening on Earth. The world’s richest man is preventing lifesaving aid from reaching the world’s poorest children, closing off their future as he fantasizes about another."

I genuinely think some people do not want to look this in the eye/think about it because it is so awful. We wrote what I thought was a pretty eye-opening story about all this and I was surprised by the lack of engagement tbh

I have just emailed Dr. Bhattacharya ([email protected]) to express my opinion: t he should be deeply ashamed to have stopped the CDC publication that COVID vaccines are safe & effective. I asked him to publish the report with an apology and statement that the findings are correct.

Bhattacharya is an embarrassment. He is not fit to lead NIH.

Shame of Bhattacharya for canceling the release of findings that (Covid) vaccines are safe and effective. This is not honest, rigorous, or scientific.

There is a distinct possibility that this continuation will be made permanent. This effectively triages 2/3 of the applications submitted, because the selection of the “conpetitive ND” apps for funding is vanishingly rare (so far). Scientists need to make some noise!!!

NIH is not okay. @nytimes.com highlights how grant-making & ability to obligate funding is at risk from staff shortages and time consuming screening processes designed to censor research to align with the administration's political ideology. www.nytimes.com/2026/04/22/s... Some highlights:

The irony - painting in background shows George Washington, who had his troops vaccinated against smallpox.

New work from my team: pubs.acs.org/doi/10.1021/... We used probes to ID targets of carbapenems in M. abscessus. 17 targets active in both carbon starved and replicating cultures. Includes validation of 9 targets. Part of a special issue ("NTM Pathogens – Biology, Infection, and Drug Discovery).

Today, I was asked by a grandparent about benefits vs risks of vaccines, so she can talk to her kids & grandkids I shared this superb infographic @peterhotezmdphd.bsky.social, published @plosglobalpublichealth.org We need such infographics for all vaccines!! journals.plos.org/globalpublic...

Over the seven decades since the polio vaccine, we have seen this pattern again and again. Vaccines have a great track record.

@hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits Stable, sustained support can transform your career: Senior Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

It’s really that simple No child needs to suffer from measles

Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...

I don't use AI for my scholarly writing. My papers/reviews/grants/etc. are original text generated by me. Because of this, I am deeply uncomfortable with the theft of written work/ideas from authors and scholars to train large langue models. I agree with is: 👇 www.chronicle.com/article/big-...

I am looking forward to the 2026 PacTB meeting, which starts in less than an hour. @ohsunews.bsky.social is hosting this year, and attendees will come from across the west coast to discuss mycobacterial pathogens. 🧫💉🔬🦠

I absolutely have a viewpoint. Until recently, the US was a leader in research & NIH was something of which all Americans could be proud. Productive, innovative, life-saving. Trump, RFK Jr., and Bhattacharya are systematically destroying our research capacity. I won't be silent in my dissent.

Such an amazing moon we have. www.nasa.gov/image-detail...

The President's fiscal year 2027 Budget was released today. Important---Important---Important The President's Budget is always fundamentally a political document that Congress may or may not (usually not) take very seriously. www.whitehouse.gov/wp-content/u... 1/9

My most recent PhD candidate, who was amazing (Julia Doh) defended in April 2020. I love working with graduate students, but OHSU's program is small (15-20 students/year for all the faculty). Advice?

I serve on NIH study sections. I consider it a privilege and a duty. It is hard but rewarding work. Right now it seems like the least I can do to support our colleagues at NIH.

I place a really high value on a college education. I wish that college was more accessible. Yet, I found this article absolutely fascinating. The ROI varies widely-- I wish that programs/colleges were forced to disclose this information. freopp.org/whitepapers/...

Spring has arrived in Oregon.

Color chemistry

From Galbraith & Galbraith: “tradewinds” bring soluble proteins to the leading edge – with a nice assortment of microscopy approaches including iPALM www.nature.com/articles/s41...

Thank you so much for holding Bhattacharya responsible for his lies.

We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...

I wish Trump, Musk, and RFK Jr. could directly observe the suffering & deaths that they are causing. This call to action for WHO is timely because, as stated, "...the US’s recent decisions have greatly amplified the risk of multiple international outbreaks of disease". www.bmj.com/content/392/...

The vaccine news headlines are frustrating-- they read like there is new information. "Vaccines prevent measles!" "Vaccines save lives!" They should be accompanied by a 1950s voice-over like those jokey documentaries on film strips for kids.

Following @joshuasweitz.bsky.social post and discussions with him and the Vox story, I have estimated R01 success rates for each NIH institute and center with enough awards for this to be meaningful. A long 🧵... 1/25

Big surprise, the DOGE wrecking ball made a lot of bad decisions, with no expertise, with no clear thought, and their actions were most likely illegal. I co-blame Musk and Trump for this one, but Michael McDonald's complicity should cost him his job. www.insidehighered.com/news/faculty...

There is no logic behind cutting NSF fellowships. None. Sabotaging the NSF fellowship is a blunder | Science www.science.org/doi/10.1126/...

Cracked, but still there: the glass ceiling persists for senior women in science www.nature.com/articles/d41... It is depressing to know that I have been reading articles like this for most of my career and that I will likely keep reading them for the next 20 years. Yes, gender bias persists.

I was using @chimerax.ucsf.edu just now and three of my enzymes look like the cutest lil' sea horses. Happy weekend!

Jerrie Cobb was an outstanding pilot who out-performed nearly all of of the men at NASA who were training/testing to go to space. Didn't matter. She was denied the opportunity, again and again, because she was female. This is the country we live in. www.lowellmilkencenter.org/programs/pro...

The future of research is imperiled by the drop in NIH funding for ESIs under Bhattacharya's leadership. He claimed that ESIs were get funded because of "affirmative action". When ESI funding rates drop, ESI will be forced to leave science. Also look here: drugmonkey.wordpress.com/2026/02/26/n...

Recently doing many TLCs and I didn't really appreciate how important it was to saturate my chamber. Now I know! 👇 Let Us Teach Proper Thin Layer Chromatography Technique! | Journal of Chemical Education pubs.acs.org/doi/10.1021/...

I have served on study section for many years now. It is absolutely critical that we support early stage investigators (ESI) and new investigators during grant review and funding. The playing field is not level.