🌿 The Botanical Garden of Charles University’s Faculty of Science turns 250! Founded in 1775, it is one of Central Europe’s oldest university gardens. Join us for a special anniversary program 15–21 Sept 2025. 🎉 @unikarlova.cuni.cz @botanickazahradauk.bsky.social

today #3Dprint protein is ferritin (PDB: 6I36) available here: www.printables.com/model/141627...

Kickstarting our symposium “Protein Annotations in the age of AI” at UCL!

We opened Day 2 of our #CECAM flagship workshop in Prague with the CECAM director Andrea Cavalli, highlighting steered #MD, dynamical docking & the complexity of binding energetics, and the challenges ahead. 🚀 #CECAMinPrague @iocbprague.bsky.social @cecamevents.bsky.social @iocbtech.bsky.social

CATH turns 30 years old 🥳 They celebrate with a Symposium on September 16th! I'll be presenting our work: "An Atlas of Energetic Evolutionary Constraints Across Protein Families" Unbelievable selection of speakers! So if you are around London, you can register to attend: tinyurl.com/2pnk8hj5

The first day of our bioML symposium at @iocbprague.bsky.social went very well. It is amazing to see how fast this field is moving forward. Thanks to everyone for the fantastic talks! 🤖🧬

🚀 GPU-accelerated docking to P2Rank-predicted pockets

Fantastic to work with so many talented people! today at departmental conference of cell biology department of @sciencecharles.bsky.social . Many thanks to our guests from Israel for joining us and sharing their results and time with us

Congratulations! 🎉

🚀 Our paper on the updated PrankWeb, a web app for protein binding site prediction using P2Rank, is out in @narjournal.bsky.social. Now with docking integration! 👨‍💻 Try it: prankweb.cz 📄 Paper: doi.org/10.1093/nar/... 💻 GitHub: github.com/cusbg/prankweb Developed at @cusbg.bsky.social

I am #exhilarated to share that our new paper "LIGYSIS-web: a resource for the analysis of protein-ligand binding sites" is now published in @narjournal.bsky.social! After almost two years of development and more than 600 commits, LIGYSIS-web is out! 📜 : tinyurl.com/utges-LIGYSI...

Join us for the next #Bioinformatics seminar hosted by @sciencecharles.bsky.social and @mff.unikarlova.cuni.cz. Nora Martin from CRG : “How does the structure of a genotype-phenotype map shape variation and evolutionary processes?”. 📅 Wed, Apr 30 🕕 17:20 bioinformatics.cuni.cz/seminar

Back in July 2023 we organized a small bioML symposium at @iocbprague.bsky.social, and it turned out to be a very pleasant and successful event. This summer we are following up with a great line-up of speakers. Please register for free, deadline May 30. tinyurl.com/bioMLPrague25

3DSIG has now joined BlueSky!! Follow us there to keep building a strong community around the fields of Structural Bioinformatics and Computational Biophysics!

A new preprint from our lab at @fchupol.bsky.social

🧪🇨🇿 A reminder: there’s a starter pack with Czech science institutions and research labs. A bunch of new ones have joined Bluesky lately -- and some, like Charles University (@charlesuni.cuni.cz), have fully made the move here from the other place.

Joe et al. have a fresh preprint on the MARTINI simulations of the #ribosome. arxiv.org/abs/2503.21357

we continue 1st @elixircz.bsky.social PhD conference with keynote by Martin Čech from @iocbprague.bsky.social and Cesnet on usegalaxy.cz

1st @elixircz.bsky.social PhD conference at Telč on 27-28th March 2025 superthread.

🎉 #ELIXIRCZ celebrated 10 transformative years in life sciences! Thanks, everyone, for celebrating with us! 🥂 Cheers to a decade of growth & many more to come! #Science #Innovation #DataScience @elixir-europe.org www.elixir-czech.cz/news/10-year...

we continue 1st @elixircz.bsky.social PhD conference (I should made a hashtag - too late) with student presentations

We are grateful and fortunate to have Sameer Velankar, the head of @pdbeurope.bsky.social, to start first ever @elixircz.bsky.social phd conference. Thank you RSJ and @elixircz.bsky.social for general support!

we continue with keynote lecture by Sameer Velankar from @pdbeurope.bsky.social

1st @elixircz.bsky.social PhD conference just started with @majek.bsky.social invitation

🎉 ECCB is now on Bluesky! Follow us for: ✔️ Latest conference updates ✔️ Key dates and calls ✔️ Networking & collaboration opportunities Join the ECCB community! #Bioinformatics #DataScience #CompBio

🚀 Exciting news! We're organizing a @cecamevents.bsky.social Flagship Workshop on Quantum Chemistry in Drug Design in Prague, Sept 8–10, 2025! Join top experts from academia & industry. Few spots left for contributed talks! 📢 Apply now: www.cecam.org/workshop-det... #compchem #cadd #QM #CECAM

Everything comes to an end but memories remain!! We had a great 3DSIG/3DBioinfo event in "sunny" Barcelona this week!! I have enjoyed so much to help organising it & to have such great minds all together sharing science for 3 days!! Aufwiedersehen friends! For more science & friendships to come! ⭐

Happy to share our latest preprint. With NRGRank you can screen 1M in a day in a laptop (use our NEGSuite-Qt for that) - a billion compounds per day with our computational resources.

and key people behind establishment of the ELIXIR CZ setup

@elixircz.bsky.social is celebrating 10th anniversary today! Jiri Vondrasek is in his summary acknowledging Janet Thornton and her contribution to founding of Elixir. Thank you!

Registration is open until March 6th!!

🧪🧬🔬 Postdoc in Computational Structural Biology at the @biozentrum.unibas.ch & @sib.swiss in Basel, Switzerland. www.biozentrum.unibas.ch/open-positio... The position is initially funded for 3 years, possibility to start immediately. #StructurePrediction, #Bioinformatics, #Uniprot3D, #AI

🚨 Unravel BILLIONS of years of protein evolution! 🚨 How did protein structures emerge and evolve over deep time? Join @zachary-ardern in the next ProSE Seminar! 📅 March 11, 3PM GMT 🔗 tinyurl.com/prose-seminar2 #ProteinEvolution #StructuralBiology

ROCKET #Alphafoldology fitting to lowres CryoEM to get conformation along the way

Counterintuitive

Join us tomorrow to hear @peterskrinjar.bsky.social talk about 🌹 Runs N' Poses 🌹! Curious to hear your thoughts on how to keep up with benchmarking in this field.

RT please: Just 1.5 months away from our joint 3DBioinfo/3DSIG amazing conference! These are our two great keynote speakers! @rolanddunbrack.bsky.social & @silviaosuna.bsky.social! Check our preliminary programme here: www.iscb.org/3dbioinfo202... Registration link: www.iscb.org/3dbioinfo202...

If you’re submitting to the @narjournal.bsky.social Web Server/Database issue and need to add PMC and DOI links to your #BibTeX as required—but the provided Perl script isn't working—I’ve created a small Python script to help you out! 🔗 github.com/davidhoksza/...

Important #AlphaFoldology thread about scoring intramolecular complexes in #AF2 and #AF3

🚀 New Paper Alert! 🚀 𝐑𝟐𝐃𝐓: a comprehensive platform for visualising RNA secondary structure Check it out in @narjournal.bsky.social: academic.oup.com/nar/article/... Here’s why you should give it a try 🧵👇

Excited to announce the upcoming @elixircz.bsky.social PhD Conference in #Bioinformatics, #Chemoinformatics, and #ComputationalBiology! Join us for 2 days of student presentations, a posters, and insightful discussions with distinguished scientists. 🧬https://bioinformatics.cuni.cz/phdconf2025

How long does it take to predict ligand binding sites for all 220k proteins in the PDB? P2Rank 2.5 does it in 3 hours on a single CPU (16-core amd 5950x)—2x faster than the previous version 🚀. (1/n)

I didn't know that... Or did I? You can pretty much do anything in sequence and structure analysis with Jalview! ANYONE: "Hmmm, I wonder if I could cluster a group of sequences by features such as predicted ligand sites and then analyse amino acid conservation within each group..." 🤔 #JALVIEW: YES

We’ve been benchmarking deep learning co-folding methods for protein-ligand complex prediction, leading to the creation of 🌹Runs N’ Poses🌹. Great effort by @peterskrinjar.bsky.social and @jeeberhardt.bsky.social putting this together so quickly. Please have a look, excited for community feedback!

Things are often obvious, but sometimes less so. It is true also for small things like ligand-binding sites. In this work, our @cusbg.bsky.social group presents a new dataset designed for cryptic-binding site predictons - happy, to be part of this: academic.oup.com/bioinformati...

Welcome a new doctor! My student has successfuly defended his thesis on diversity of ligand binding sites today! Congratulations, Christos Feidakis!

Two of our colleagues at the department of cell biology @sciencecharles.bsky.social just received Neuron prize. Congratulations, Klara Hlouchova and Jan Cerny. www.nadaceneuron.cz/ceny-neuron-...

Congratulations, Klara! Look forward to our next project!