Marian Novotny
@majek.bsky.social
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📥 218
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Proud dad, structural bioinformatician, cook, birdwatcher and skater
Congratulations, Vaclav!
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3 days ago
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Alessandro Nascimento
3 months ago
👇🏾👇🏾👇🏾
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Pedro Beltrao
3 months ago
Great work from Horia Todor in Carol Gross's lab showing it's possible to predict complexes in "competition" pools in AF3 resulting in the first all-by-all prediction for a species. After length correcting the ipTM score predicts well known interactions and correlating ipTM vectors also has value.
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Fantastic to work with so many talented people! today at departmental conference of cell biology department of
@sciencecharles.bsky.social
. Many thanks to our guests from Israel for joining us and sharing their results and time with us
3 months ago
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@vaclav-veverka.bsky.social
presents his phase seperation doubts
#theconferencetoendallconferences
#TCTeAC
4 months ago
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P2Rank has a new version - you can even see a ligand bound to the identified pocket now - please , check it out and look at our NAR paper for a summary of the upgrades
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4 months ago
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Deník N
4 months ago
„Hledání života ve vesmíru je pro mě asi největší vědecké dobrodružství,“ říká jedna z nejúspěšnějších českých vědkyň, biochemička a astrobioložka Klára Hlouchová. Zkoumá otázky původu a evoluce proteinů. Co ještě není, a co už je schopno života?
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Nález života ve vesmíru by s námi mohl pěkně zamávat, říká astrobioložka. Zkoumá vznik života i slepé uličky
Co ještě není, a co už je schopno života? A jak by mohl vypadat život ve vesmíru? Biochemička a astrobioložka Klára Hlouchová zkoumá otázky původu a evoluce proteinů. A otázky života, vesmíru a tak…
https://denikn.cz/1738235/nalez-zivota-ve-vesmiru-by-s-nami-mohl-pekne-zamavat-rika-astrobiolozka-zkouma-vznik-zivota-i-slepe-ulicky/?ref=tit1
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Jalview team strikes again! Congratulations!
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5 months ago
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We are grateful and fortunate to have Sameer Velankar, the head of
@pdbeurope.bsky.social
, to start first ever
@elixircz.bsky.social
phd conference. Thank you RSJ and
@elixircz.bsky.social
for general support!
6 months ago
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@elixircz.bsky.social
is celebrating 10th anniversary today! Jiri Vondrasek is in his summary acknowledging Janet Thornton and her contribution to founding of Elixir. Thank you!
7 months ago
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Congratulations, i wonder whether the current tools can move ligands to right places…
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8 months ago
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Counterintuitive
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8 months ago
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Things are often obvious, but sometimes less so. It is true also for small things like ligand-binding sites. In this work, our
@cusbg.bsky.social
group presents a new dataset designed for cryptic-binding site predictons - happy, to be part of this:
academic.oup.com/bioinformati...
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CryptoBench: cryptic protein–ligand binding sites dataset and benchmark
AbstractMotivation. Structure-based methods for detecting protein–ligand binding sites play a crucial role in various domains, from fundamental research to
https://academic.oup.com/bioinformatics/article/41/1/btae745/7927823
8 months ago
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Česká společnost ornitologická
8 months ago
🪶Nečekané a vzácné pozorování pelikána bílého ve čtvrtek v ptačím parku Kosteliska na Hodonínsku. Pták byl v dobré kondici, bez chovatelských kroužků a často ladně přeletoval a kroužil. Jedná se již o 209. ptačí druh pozorovaný v ptačím parku ČSO Kosteliska. Foto: Ondřej Ryška
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An important extension ofPyMOL by Rafi’s
@rnajmanovich.bsky.social
group
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8 months ago
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Two of our colleagues at the department of cell biology
@sciencecharles.bsky.social
just received Neuron prize. Congratulations, Klara Hlouchova and Jan Cerny.
www.nadaceneuron.cz/ceny-neuron-...
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Ceny Neuron 2024
Nadace Neuron udělila prestižní vědecká ocenění excelentním vědkyním a vědcům
https://www.nadaceneuron.cz/ceny-neuron-2024
8 months ago
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Welcome a new doctor! My student has successfuly defended his thesis on diversity of ligand binding sites today! Congratulations, Christos Feidakis!
8 months ago
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Karel "CaCO3" Berka
10 months ago
#CASP
ligand
#Alphafoldology
-
#AF3
wins over all other methods in baseline ligand prediction…
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Congratulations, Klara! Look forward to our next project!
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10 months ago
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estella newcombe
10 months ago
We did this crazy project where we tried to see if proteins could interact with their mirror image ligand. Seems impossible when proteins need to form 3D structures to interact. But what about if the interaction remains disordered???
www.nature.com/articles/s41...
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Stereochemistry in the disorder–order continuum of protein interactions - Nature
Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.
https://www.nature.com/articles/s41586-024-08271-6
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Congratulations to Honza and his great team!
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10 months ago
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Happy to wait!
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10 months ago
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Highly recommended!
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10 months ago
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Radoslav Krivak
10 months ago
Trying to collect scientists in/from Czech Republic who are here. Let me know who should I add!
go.bsky.app/Q4XavnF
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you reached the end!!
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