How do flexible regions of histone chaperones team up to handle histones? Together with Fred Winston’s lab @harvardmed.bsky.social, we reveal new insights in our study just out in Mol Cell. Hats off to James Warner and Vanda Lux @iocbprague.bsky.social for their key contributions! dlvr.it/TNB145

New work from the Moazed lab reveals the requirements for establishment & epigenetic stability of mammalian heterochromatin! www.cell.com/molecular-ce...

🧬 Transcription elongation by RNA polymerase II relies on a web of elongation factors. Our new work shows how IWS1 acts as a modular scaffold to stabilize & stimulate elongation. Fantastic work by Della Syau! www.biorxiv.org/content/10.1...

Chromatin remodelers engage with transcription factors through β-catenin. A new story from @hodgeshc.bsky.social and @cermakova.bsky.social in Mol Cell reveals a key role for intrinsically disordered regions. Congratulations! We're really happy to help out.

#TCTeAC awesome crowd

Exploring unsettled biomolecular interactions with an NMR twist. A joint effort with the Obsil lab. www.nature.com/articles/s41...