Expression of vimentin intermediate filaments in epithelial cells promotes cell migration and cell matrix interaction in 3D https://www.biorxiv.org/content/10.1101/2025.09.18.677142v1

Have you ever wondered how microtubules withstand and respond to mechanical stress in cells? Here we show by in vitro reconstitution assays that MAP65-1 and PRC1 promote microtubule nucleation on existing lattices, especially on those with structural irregularities linked to mechanical stress.

Here's some more exciting new news from the microtubule world ✨Great work from @marianattom.bsky.social the @schaedellab.bsky.social showing how MAP65-1/PRC-1 reinforce microtubules under mechanical stress. Look at them microtubule arrays in plant cells 😍 ( To quote Verstappen, "Simply lovely")

Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9) www.biorxiv.org/content/10.1...

Congratulations, Subham 🎉🎉🎉 Great study and uber cool microtubule self-repair images that I can stare at for hours 😍😍😍

Upcoming interdisciplinary meeting: Cell Physics 2025 When? October 7-9, 2025 Where? Saarbruecken, Germany Relevant dates? Early-bird deadline: June 30, regular registration by August 31 Several opportunities for short-talks selected from abstracts More info at: cell-physics.uni-saarland.de