Ennio
@amicoennio.bsky.social
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A biochemist. Molecular motors, especially dynein.
Thrilled to have been awarded a BBSRC Fellowship! ๐ An exciting new chapter, continuing in the
@carter-lab.bsky.social
at
@mrclmb.ac.uk
โ studying how molecular motor function is rewired during cell division. Hugely grateful to Andrew for his support and mentorship ๐
www.ukri.org/news/bbsrc-i...
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BBSRC invests in 21 new Fellows
BBSRC invests ยฃ10 million in 21 new Fellows as part of its ongoing commitment to develop the next generation of independent research leaders across the UK.
https://www.ukri.org/news/bbsrc-invests-in-21-new-fellows/
15 days ago
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New preprint! We asked a simple question: How do very different activating adaptors all activate dynein? Turns out: same architecture, wildly different implementations ๐งต๐
doi.org/10.64898/202...
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https://doi.org/10.64898/2026.04.25.720804
2 months ago
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Ennio
Viji Draviam
2 months ago
@bscb-official.bsky.social
Beautiful Cryo-ET talk by Kashish Singh on cytoplasmic lattices in mammalian embryos from
@mrclmb.ac.uk
at the
#DynamicCellVI
conference
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Ennio
Kashish Singh
3 months ago
Happy to share my first adventure in
#TeamTomo
in collaboration with the talented
@inaharasimov.bsky.social
. It was a fun experience experience with a lot of learning along the way.
add a skeleton here at some point
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Today in
#journalclub
- An isoform of my favourite mitotic adaptor Spindly is repurposed to regulate lipid droplet localisation in interphase. Worth a look ๐
advanced.onlinelibrary.wiley.com/doi/10.1002/...
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https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
6 months ago
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Ennio
Verena Cmentowski
10 months ago
Excited to share our new paper! ๐ The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
www.science.org/doi/10.1126/...
Very thankful to
@andrea-musacchio.bsky.social
for his mentorship and support over the years.
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The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
The kinetochore fibrous corona docks on CENP-E and a second elusive receptor identified as the checkpoint protein BUB1.
https://www.science.org/doi/10.1126/sciadv.ady6890
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Ennio
Andrea Musacchio
10 months ago
The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances
www.science.org/doi/10.1126/...
Congratulations
@vcmentowski.bsky.social
for solving a remarkably challenging molecular puzzle
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The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona
The kinetochore fibrous corona docks on CENP-E and a second elusive receptor identified as the checkpoint protein BUB1.
https://www.science.org/doi/10.1126/sciadv.ady6890
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The power of collaboration (and of in vitro reconstitution)!
add a skeleton here at some point
over 1 year ago
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reposted by
Ennio
Journal of Cell Biology
over 1 year ago
New: Colombo et al.
@surreylab.bsky.social
show that NuMA is a mitotic dynein adaptor that binds and caps microtubule minus ends, explaining how dynein, NuMA, dynactin, and Lis1 focus microtubule minus ends at mitotic spindle poles
https://buff.ly/41aj9F9
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Excited to share the first published paper of my postdoc - a collaboration with Yildiz and Dumont groups led by Merve Aslan, on the fascinating dynein adaptor NuMA. Lots of super cool insights on how NuMA can activate dynein during mitosis. Thanks to
@carter-lab.bsky.social
for the support!
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https://www.biorxiv.org/content/10.1101/2024.11.26.625568v2
over 1 year ago
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Ennio
over 1 year ago
Our
#CryoET
paper on ciliary rootlet ultrastructure from mouse retina is now out in
@elife.bsky.social
! Have a peek with this video or dive deeper at
bit.ly/3ZJzhgc
. Big thanks to
@carter-lab.bsky.social
and
#teamtomo
.
#CryoET
#CryoEM
#Cilia
#Rootlet
#Centriole
#Research
#Science
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Brilliant and supportive mentor, great location, exciting project - what's not to love? Plus a unique opportunity to really learn from the best at figuremaking!
add a skeleton here at some point
over 1 year ago
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First
#JournalClub
on the blue side: an exciting story about dynein at the kinetochore and its role in biorientation!
www.nature.com/articles/s41...
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Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore - Nature Communications
Mitotic chromosomes recruit multiple microtubule-directed activities to ensure their faithful segregation. Using an approach where only one major activity is present, the authors reveal sufficiency of...
https://www.nature.com/articles/s41467-024-52964-5
over 1 year ago
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