An empirical approach to evaluating the prevalence of long-lived balancing selection in humans--and important limitations. Work by @hannahmm.bsky.social

I recently moved my lab to Purdue University and am looking for graduate students. We are working at the interface of population genomics, quantitative genetics and functional genomics to understand how plants adapt to extreme environments. Reach out if you would like to discuss potential projects.

Conrad Hal Waddington was born OTD in 1905. His “epigenetic landscape” is a diagrammatic representation of the constraints influencing embryonic development. On his 50th birthday, his colleagues gave him a pinball machine on the model of the epigenetic landscape. 🧪 🦫🦋 🌱🐋 #HistSTM #philsci #evobio

I want to do this PhD!!

Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇

New in ‘Virus Evolution’ from #QVEU! PhD student Jack Dorman used deep mutational scanning to measure evolutionary constraints on the Envelope protein of West Nile Virus in human, mosquito, and bird cell lines, doing a lot of work to put it into a structural context #VirEvol

National Guard giving out Halloween candy at the U street metro if you are interested!

The Johri Lab has an open postdoc position. Please send me an email, if interested. Start date is flexible. Please do share! Thank you in advance.

We are searching for a lab manager! If you are detailed oriented, like southern california, HSV-1, sequencing and microscopy, please get in touch :)

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪 careers.umass.edu/amherst/en-u...

New Cambridge Element in the Philosophy of Biology series—fully #openaccess! @thomasreydon.bsky.social explores how evolutionary theory crosses over from biology into other fields, showing how these crossovers embody a broader style of reasoning: 'evolutionary thinking' bit.ly/48z3h36 #HPbio #evosky

New #QVEU preprint! @williambakhache.bsky.social used our #EV71 mutational scanning library to dissect replication complex function with a collection of inhibitors against specific host and viral factors. Then used the data to validate structural predictions! Super cool #virosky #virus #evolution

🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine. 1) MMG (my dept): fundamental research in med micro 2) Peds ID / I4Kids institute 3) Center for Vaccine Research 🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...

First ever #QVEU lab “field trip” during group meeting as @orrwalk.bsky.social told us all about his summer research on powdery mildew! Fascinating!

The constant barrage of terrible news on bluesky has made me feel weird about promoting papers, but people in the lab have been doing so much amazing work over the past few months that I want to share a few brief teasers/links:

New study! We compared the first two full-proteome Enterovirus DMS datasets and found both shared and unique selection pressures—plus conserved druggable pockets. Great collaboration with @ptdolan.bsky.social ’s team! dx.doi.org/10.21203/rs.... @bealro.bsky.social @i2sysbio.es

Congratulations to the great Kanta Subbarao—the unanimous choice of the awards committee to receive the Edward Jenner Award! Nobody is more deserving for her contributions to developing vaccines for bird flu & other emerging respiratory pathogens. #19vaccinecongress

Latest work from our lab from Ashley Della Fera 😀

How can we understand the earliest events in evolution of eukaryotic immunity? @yao-li.bsky.social reports incredible molecular fossils of complete bacterial-like operons in eukaryotes that illuminate how animal immunity was first acquired from anti-phage defense www.biorxiv.org/content/10.1...

Gill, @lemeylab.bsky.social et al. develop Bayesian infinite mixture models for phylogenetic inference, finding that infinite hidden Markov models best capture complex patterns in large datasets; they implement this framework in BEAST X. 🔗 doi.org/10.1093/molbev/msaf199 #evobio #molbio

🚨 Job Alert! 🚨 Assistant Professor in Global Change and Disease Ecology at Stony Brook University, Department of Ecology & Evolution. Deadline: October 1. #AcademicJobs #tenuretrack #facultyjobs apply.interfolio.com/171403 (I love being here. Come join!) @stonybrooku.bsky.social

We are hiring into 3 (THREE!) tenure track lines this year at Wake Forest — if you’re looking please reach out, I love chatting about our department! We are a vibrant group that love & embrace the teacher-scholar model 👩‍🏫

Calling all #Microbes25 enthusiasts, it’s time to show off your finest science. Do not leave it trapped in your lab. Submit your abstract by September 4 & have a chance to win the Nature Microbiology Poster Prize: vibbio.tech/3UQkrkN. @natmicrobiol.nature.com #MicrobialBiotech #MicrobialEcology

Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...

New preprint: we developed a method that uses phosphoproteome-derived peptide libraries (PhosPropels) for deep specificity profiling of phosphatases and phospholyases www.biorxiv.org/content/10.1...

Check out (and support!): “The Orphan Race”, the Illustrated Science Fantasy Debut by #friendofthelab and fellow virologist, Jenny Jones, on @kickstarter.com www.kickstarter.com/projects/jen...

ROI on investment now in maintaining the pipeline has never been higher. If we don't maintain the pipeline, ROI on future investment will be lower than ever before. One doesn't need a PhD in economics to figure out that withdrawing pipeline funding here and now is either foolishness or cowardice.

Three months ago I wrote about how there has never been a more important time for private philanthropy to support the junior scientists and invest in maintaining the talent pipeline previously supported by federal funding. Here's the thread: bsky.app/profile/carl... But instead:

Time’s running out! We’re hiring 1 Scientist + 2 Postdocs at @PasteurCambodia’s #Virology Unit to work on emerging viruses & #zoonoses. If you want to do real-time science that matters—this is your chance. Apply now. Start soon. 🦠🔬🧪🐓💉🦇😷🥼 #academicjobs #OneHealth #Virology

New JCI paper led by postdoc Mikal Woods Acevedo shows immune cell infiltration—not viral load—drives paralysis in mice infected with enterovirus D68. Points to new targets for AFM treatment. 🔗 doi.org/10.1172/JCI1... #Virology #NeuroImmunity #PostdocSpotlight #AFM

A or B? Yes!

Hi #EvoSky #evobio - @biomedcentral.bsky.social BMC #Ecology and #Evolution is currently accepting submissions to a Special Collection “Evolution of disease: From pathogens to proliferating cells”. Please consider submitting your work! Deadline is March 16th. www.biomedcentral.com/collections/...

Know an Evolutionary Genomicist looking for a faculty position? Join us in EEB @utknoxville.bsky.social Position is open for studying any organism, but personally I have some botany bias. 🌱 Apply before Sept 19 for full consideration. apply.interfolio.com/170735 Please share widely. Thanks!

A postdoc position working on marine phage - please share widely!

Pospelova et al. present a comparative analysis of full-length sequences of IG/TR loci across 46 mammalian species, demonstrating these as rapidly evolving genomic regions, with implications for immunogenomics. 🔗 doi.org/10.1093/molbev/msaf152 #evobio #molbio

Gillian Welch released ‘Time (The Revelator)’ 24 years ago on July 31, 2001 album.ink/GWelchTTR

We are excited to announce the SMBE Fellows Program! ✍️ Designed to provide networking and mentorship opportunities to early-career researchers through scientific writing in evolutionary biology for @molbioevol.bsky.social and @genomebiolevol.bsky.social 📆 Aug. 31 🔗 smbe.org/smbe-fellows-program

📣 I'm recruiting a postdoc researcher to join my team for a project on mosquito-specific viruses and host interactions. Peep the job description & how to apply below. Perfect for soon-to-be or recent PhD graduates in mosquito vector biology 🦟 or arbovirology 🦠 🗓️ Application deadline 31 August 2025

Kenyon is hiring a TT microbiologist! Please share widely. I’m the search chair & am happy to answer any questions. careers.pageuppeople.com/695/cw/en-us...

Come to join us! 🎉🫶 The Department of Biology invites applicants for a tenure-track, Assistant Professor of Biology position! Learn more about the Department of Biology here: www.wcupa.edu/sciences-mat..., and apply online at www.schooljobs.com/careers/wcup...

Apply!

🎲 Our paper on the genetics, energetics, and allostery in proteins with randomized cores and surfaces is out today @science.org! 🧬 By charting a protein’s sequence universe, we could rationalize which versions were kept through evolution – and why many stable ones were not.

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome. See thread for more information and reach out!

This thread captures what is so cool about science - the intersection of people and ideas that leads to lifelong collaborations and friendships, usually by serendipity. @triggerloop.bsky.social @briandilkes.bsky.social

#ASV2025 in Montreal was a great success, I had a lot of fun. See you in Minnesota! Congrats to @orrwalk.bsky.social and Jack Dorman for representing the #QVEU so well.

This year's Trainee Satellite Symposium at #ASV2025 is a trainee-only session "Exploring the Intersection of Culture, Communication, And Mentorship in Science". It will feature speakers Beronda Montgomery, Robert Fernandez, and Olivia Goldman. Find out more here: asv.org/2025/06/19/t...

New #postdoc opportunity at #NIH! Especially those interested in #quantitative methods and modeling of #cell #signaling. Mia is awesome!