“This administration has mis-used the term ‘DEI’ to eliminate policies and practices that were intended to broaden the diversity of human study participants,…support studies focused on health disparities,…and foster the inclusion of people with diverse backgrounds…in the scientific workforce.”

"Go climb the highest mountain. I may not get there with you. Go cross the harshest desert. I may not get there with you. Go swim the deepest ocean. I may not get there with you. But I will join you when I can." I wrote this song in honor of the Rev. Dr. Martin Luther King, Jr. Gone 58 years today.

Congratulations to John R. Yates III, Ruedi Aebersold and Matthias Mann, recipients of the 2026 Canada Gairdner International Award. Prof. Yates: www.gairdner.org/winner/john-... Prof. Aebersold: www.gairdner.org/winner/ruedi... Prof. Mann: www.gairdner.org/winner/matth... #2026GairdnerAwards

You could say that Rock n Roll was born 111 years ago today in Arkansas, but probably not where you'd think. Before there was a Chuck Berry or Little Richard, there was those who wanted to be like her. Rosetta Nubin better known as Sister Rosetta Tharpe, the godmother of Rock was born on this day

It’s insane that America has never put Louie Armstrong or Duke Ellington or Ella Fitzgerald on currency but it’s about to mint a Donald Trump coin.

These protein-like polymers may help target intractable cancer-causing proteins: cen.acs.org/biological-c... #chemsky 🧪

This is great news, and I hope all vendors continue to support THE vendor neutral option for MS data. Regardless, it was a shame that Skyline went without funding for a year from SCIEX My dream is that Skyline is funded by all vendors continuously. All of #teammassspec benefits from the arrangement

New preprint! We did a systematic comparison of proteases, digestion conditions, and labeling methods for histone PTM analysis by MS-based proteomics in the Yates lab at @scripps.edu. TL;DR: you can get great results in ~3 h of sample prep. 🧵

We need to get more mass spec proteomics folks on here and increase the size of our cluster! #Proteomics #TeamMassSpec bluesky-map.theo.io

We'll pick it up from here. Spring Training and the World Baseball Classic are right around the corner!

1. It was not an accident. 2. It was not a staffer. 3. While the president may have dementia his racism is not due to dementia. 4. He isn’t sorry. He means every racist thought he shares. 5. His base agrees with him. 6. He will do it again. 7. No one in power will hold him accountable.

#BelfastMaine #IceOut #Maine @pinetreeactivism.org Belfast Maine, Pop. 7500

a few thoughts youtu.be/lERS4kJIQR8

I’m proud to be leading this fight. Thank you to @maddowblog.bsky.social for highlighting this critical issue.

Our latest article is out in Cell ! Together with the Zernicka-Goetz lab, we show that fertilization triggers proteomic asymmetry in mammalian zygotes, giving rise to alpha vs. beta 2-cell blastomeres with distinct developmental potential. cell.com/cell/fulltex...

An inspirational example of 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐜𝐫𝐞𝐚𝐭𝐢𝐯𝐢𝐭𝐲, 𝐨𝐫𝐢𝐠𝐢𝐧𝐚𝐥𝐢𝐭𝐲 𝐚𝐧𝐝 𝐫𝐢𝐠𝐨𝐫: Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...

I’ve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.🧪 My story in @science.org (and 🧵on why it's important to come): www.science.org/content/arti...

Maine has voted in a landslide to reject a Republican-supported ballot initiative that would have restricted voting access heading into the critical 2026 midterms

Turn the volume up!

“Tell your children who the cowards were.”

The antibodies don’t work! The race to rid labs of molecules that ruin experiments Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this. www.nature.com/articles/d41...

Let's see how that government ban on White House demolition photos is going. www.pbs.org/newshour/pol...

Vanderbilt response to the Trump ‘compact’ is too clever by half. Dodging the immoral dominance play and pretending it’s a reasoned conversation. Vandy wishes to play ball as an elite institution on a level with MIT, Penn and UVA. Struck out looking.

I repeat myself: this is a town of 6000 people in Waldo County, Maine

1700 people out for No Kings in rural Rockland, Maine today… more than 4% of the population of Knox County. #NoKings #Maine #MEPolitics

#NoKings rally Rockland Maine

Speculation: There has been a recency bias in citations for a long time, because the newer work should contain more up-to-date knowledge. This could reverse. People might increasingly refer to work before the 2020s, because it wouldn't have been corrupted by gen AI.

Turns out, boron-based heterocycles are anything but boring! In fact, some of them are pretty magical...1,2-oxaborines, for example, can be used as precursors to 11(!) other ring systems! Read more in my latest for @cenmag.bsky.social cen.acs.org/synthesis/sh...

People need to start highlighting that Miller is actually the shadow President and the one calling the shots. When it was Musk who was doing it, it caused a rift between them so big that after he was out, Musk was bashing Trump claiming he is in the Epstein files.

Low dose aspirin (160mg/d) reduced recurrence in people with colon cancer and PI3K mutations. Emblematic of precision, individualized medicine since the data for aspirin across all colon cancer has been mixed. www.nejm.org/doi/full/10....

Elaine Buckberg: To address "range anxiety," states should enact laws that require fast chargers to report real-time status that any EV mapping app can access via @brookings.edu Hutchins Center. www.brookings.edu/articles/cha...

70 years ago, on this date, Emmett Till was kidnapped and brutally murdered by white men. His family, including his cousin who was with him at the time, is repeating the train ride he took from Chicago to Mississippi in 1955 to mark the anniversary

Abbe Lowell and I represent CDC Director #SusanMonarez. Contrary to govt statements, Dr. Monarez has neither resigned nor yet been fired. She will not resign. We have issued the following statement:

If you measure and interpret RNA levels in single cells, read this: "𝑂𝑢𝑟 𝑟𝑒𝑠𝑢𝑙𝑡𝑠 𝑠𝑢𝑔𝑔𝑒𝑠𝑡 𝑡ℎ𝑎𝑡 𝑖𝑛𝑠𝑡𝑎𝑛𝑡𝑎𝑛𝑒𝑜𝑢𝑠 𝑚𝑅𝑁𝐴 𝑎𝑏𝑢𝑛𝑑𝑎𝑛𝑐𝑒 𝑜𝑓 𝑐𝑎𝑛𝑜𝑛𝑖𝑐𝑎𝑙 𝑚𝑎𝑟𝑘𝑒𝑟𝑠 𝑖𝑠 𝑡𝑒𝑛𝑢𝑜𝑢𝑠𝑙𝑦 𝑙𝑖𝑛𝑘𝑒𝑑 𝑡𝑜 𝑡ℎ𝑒 𝑐ℎ𝑜𝑛𝑑𝑟𝑜𝑔𝑒𝑛𝑖𝑐 𝑝ℎ𝑒𝑛𝑜𝑡𝑦𝑝𝑒 𝑎𝑡 𝑡ℎ𝑒 𝑠𝑖𝑛𝑔𝑙𝑒-𝑐𝑒𝑙𝑙 𝑙𝑒𝑣𝑒𝑙." 1/2

Protein degradation is often considered as a final step in regulating gene expression. It also regulates the first step: Transcription Many TFs, including p53, HIF-1α and c-Myc, are regulated by 𝐝𝐞𝐠𝐫𝐚𝐝𝐚𝐭𝐢𝐨𝐧-𝐠𝐚𝐭𝐞𝐝 𝐜𝐨𝐧𝐭𝐫𝐨𝐥: ⬛️ It has a key advantage. 👇

The homeless are painful to look at because they remind us of how unfair our world is, of how much suffering it contains, of how arbitrary and undeserved and precarious our own comforts and health are, of how we have failed to be sufficiently generous and merciful to others.

Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer

Holocaust and genocide scholar Omer Bartov makes it clear why “genocide” is the correct word to use to describe what Israel is doing in Gaza — with all the many legal, moral, ethical, and commemorative implications that flow from this necessary recognition. Gift link: www.nytimes.com/2025/07/15/o...

If you asked me 5 years ago if it would be possible to use a de novo tool on DIA data, I would have thought it would only exist in science fiction. Love being proved wrong. Great work from Justin Sanders. #proteomics #massspectrometry www.nature.com/articles/s41...

Make no mistake, the SCOTUS decision about birthright citizenship IS ALSO ABOUT *birthright citizenship.* The Court is using nationwide injunctions as the tail, wagging the dog, to take us back to an Antebellum view of citizenship. That way led to war once. My latest in @thenation.com

This is wild! Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol) www.nature.com/articles/s41... www.nature.com/articles/s41...

I will be damned if I allow a bunch of Confederate-waving January 6th apologists give the American people a lecture on flag waving. There is ZERO reason to enter an argument about patriotism with people who still worship traitors to America 150+ years later. They. Are. Breaking. The. Law.

A Path Forward to Save American Bio-Medical Research talkingpointsmemo.com/edblog/a-pat...

Broad industry support for Skyline and ProteoWizard has been one of the best things about our field. It has made all vendors’ instruments equally valuable in our marketplace of data. Don’t be penny wise and pound foolish #Sciex.

What is happening in Gaza will be a permanent stain on the world's collective conscience. History will never forget how our government was complicit in enabling and sustaining this ongoing humanitarian disaster. We must end funding for the Netanyahu war machine.

CVs are an important part of the validation process. However, it's possible to be measuring the wrong thing with precision. These assays need to provide data validating the specificity and linearity in addition to specificity. academic.oup.com/clinchem/adv...

I just really need everybody to understand that everything that’s happening in and to the global economy now (and all the businesses and people in it) is the entirely predictable result of the intentional decisions of one guy who doesn’t understand how the global economy works.

#MusicSky #MayTheFourth