Have you ever wondered why mice do what they do when they are free to do whatever they want? Check out our latest (and this slightly delayed thread about our recent paper, led by Caleb Weinreb and friends...) www.cell.com/neuron/fullt...

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social We gave a worm brain control of a fly body and it walked What did we learn? Nothing, other than deep reinforcement learning is effective We call it the digital sphinx www.biorxiv.org/content/10.6...

*Recruiting new group leaders* The @lmcb-ucl.bsky.social at University College London are looking for outstanding candidates to sponsor for career development fellowships. Fellows would then be assessed for tenured positions at the end of the fellowship term.

Our lab is looking for a postdoc! We have interesting projects and cutting-edge techniques such as Neuropixels Opto, Light Beads Microscopy and more. We would be delighted to receive your application. Deadline is 25 November 2025. More info here: www.ucl.ac.uk/cortexlab/po...

🚨 Please RT! We’re recruiting a motivated postdoc to dissect the neurocircuits of affective pain. Expertise in behavioral models of pain/SUDs, stereotaxy, microscopy, opto/chemogenetics, or fiber photometry encouraged. Apply 👉 recruit.apo.ucla.edu/JPF10647 #Neuroscience #Postdoc

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756

If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...

One week left to apply!

Lots of exciting clinical PhD projects at Crick - including the opportunity for neurosurgeons to work with us and record electrical activity in patients with neuropixels probes. Please share widely!

We are proud to launch what we think is going to be fantastic opportunity for pain neuroscientists and clinicians to learn the foundations of pain neuroscience

New preprint out from the lab. We identified three critical windows over which sensorimotor behaviours can be shaped. Altered early experience over these windows changes somatosensory and motor outcomes for life. Tour de force experiments by Laura Andreoli. @medresfdn.bsky.social @uclnpp.bsky.social

We're looking for a senior project coordinator in Oxford - apply by friday eng.ox.ac.uk/jobs/job-det...

We've found a new gene linked to chronic pain in humans! The gene SLC45A4 encodes (the long-awaited) neuronal polyamine transporter, which is important for pain signalling in nerves. We hope this discovery might lead to new chronic pain treatments in the future! www.nature.com/articles/s41...

We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼

1/3) This may be a very important paper, it suggests that there are no prediction error encoding neurons in sensory areas of cortex: www.biorxiv.org/content/10.1... I personally am a big fan of the idea that cortical regions (allo and neo) are doing sequence prediction. But... 🧠📈 🧪

Calling all neuroscience postdocs! Come and share your work with the London neuroscience community. No CVs, publication records or recommendation letters needed. Learn more about SWC’s Emerging Neuroscientists Seminar Series and apply by 10 July: www.sainsburywellcome.org/web/content/...

Excited to present our study in ‪@natneuro.nature.com‬: a deep brain pathway that triggers safety-driven movement—overriding needs like finding food or social contacts. A look into how the brain weighs deep instincts. Congrats to all and first author @nkrauth.bsky.social. shorturl.at/toYFN

🧠 🍄 ⚡️🐭 Now published in @natneuro.nature.com Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility nature.com/articles/s4159…

Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇

Linking function and structure at scale with X-rays - and several times over. Massive congratulations to the team ‪@yuxinzhang.bsky.social‬, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.

We've developed a way to remotely and precisely activate skin sensory neurons in mice as they naturally explore and navigate their environment - opening doors for studying sensation, behaviour, and pain in naturalistic settings. Now out: shorturl.at/ry4s9 #neuroskyence #neuroscience #PainResearch

2. Systems Neuroscience PhD position, supervised jointly with Sarah Ruediger @ruedigersarah.bsky.social This is to investigate the differential circuits involved in habitual and goal-directed behaviours. www.findaphd.com/phds/project...

1. Project on Computational Neuroscience / NeuroAI PhD, supervised jointly with Caswell Barry @caswell.bsky.social Here we want to build NeuroAI models that transform visual information to spatial navigation information. www.findaphd.com/phds/project...

New preprint ✍️🚨 ✨Ontogeny of tactile, vocal and kinship dynamics in rat pup huddling -Huddle dynamics develop w/o kinship selectivity -Vocal/internal-state quiets w/ huddling & kin/ touch in yng pups tinyurl.com/y7vhkwjc 👏 @flor-bela.bsky.social @hughtakemoto.bsky.social @kinshiplab.bsky.social

Last few days to apply to come work with our team- deadline 11th April. See details below.

New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, @liamebrowne.bsky.social and Rob Brownstone.

How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study. www.nature.com/articles/s41...

Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8

On behalf of my BSky-less student, Lisa Wooldridge: 🐭🧠💊⚡️ "Thrilled that my PhD work is on bioRxiv! I study how central amygdala (CeA) neurons contribute to opioid effects, but how specific CeA cell types drive this process remains unclear" 🧵 www.biorxiv.org/content/10.1...

🥁 Elisa Toscano idenitified a new subtype of propriospinal neurons and found a role in the execution of skilled movements🤸‍♂️. Great job from Elisa and everybody involved 💪. @alesantuz.bsky.social, @lowensteined.bsky.social. Check it out and let us know what you think: www.biorxiv.org/content/10.1...

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

Sensory inputs trigger a fast-traveling wave, followed by a slower wave carrying top-down info (value/choice). The late wave reactivates ensembles in superficial cortical layers. Touch-evoked traveling waves establish a translaminar spacetime code www.science.org/doi/full/10.... #neuroscience

Wondering about the sorts of pain research questions we ask in the lab? See this short video by the Medical Research Foundation on work they generously funded. A reminder that we have a postdoctoral position opening up in the next month! @ucllifesciences.bsky.social @ucl-neurodomain.bsky.social

Hope you'll forgive a quick thread as I take over as the new EiC of @elife.bsky.social

Thanks to all who came to support and watched online! A recording is available here: www.youtube.com/live/6LSfkQk...

Come join us at the ICN. Were looking for an Associate or Full Professor: www.ucl.ac.uk/work-at-ucl/... (these jobs aren't advertised very often!)