Awesome article on medical breakthroughs that came from basic neuroscience research in rodents. Major success examples in postpartum depression, non-opioid pain and migraine treatment. This is exactly why funding basic science is so important! www.thetransmitter.org/drug-develop...

Glad to see this published in 2025 so I can wipe it from my memory and never have to think about it again after midnight. Who reviews this junk? www.nature.com/articles/s41...

A new story at The Transmitter about the PRECISION Human Pain Network's new DRG cell atlas: www.thetransmitter.org/peripheral-n... So rewarding to hear about colleagues who are already using our datasets in their own work.

i've seen this first-hand hand now. so much effort to put together a competitive grant and 99% of applicants will have nothing to show for it

Hiring a Postdoc at UC San Diego to assist with clinical trials and neuroscience of Psychedelic-Assisted Therapy for addiction. Clinical psychology or psychiatry training preferred. Postdoc will provide psychedelic-assisted therapy sessions, analyze data, and write papers. Competitive salary! DM me.

Excited to share our new open dataset — CoSpine!😃 The first simultaneous brain–spinal cord fMRI dataset covering pain & motor tasks, now on @openneuro.bsky.social Paper in ScientificData👇 🔗 www.nature.com/articles/s41...

MSC News: The publication of a roadmap for HEAL research earlier this year sets the stage for 2026 and beyond. #painresearch #migraineresearch #headacheresearch migrainecollaborative.org/reason-for-o...

time to update my fMRI course slides (again)

My friend @alexchesler.bsky.social has left the NIH to become VP of Pain Research at Vertex. I am glad to welcome him to San Diego. Exciting for him and for Vertex. But NIH loses one of its superstars. Can’t help but wonder whether this government’s anti-science policies made that decision easier.

End of an era. Major loss for NIH and our tiny pain program at NCCIH. wishing you all the best in your next steps, @alexchesler.bsky.social

Come work with us. Huge strengths in MRI, neuroscience and musculoskeletal health and their intersections such as pain, child development or ageing. Preclinical and clinical research and translation are also big opportunities. Shoot me a note if you have questions.

Diffusion-weighted steady-state free precession imaging in the ex vivo macaque brain on a 10.5T human MRI scanner https://www.biorxiv.org/content/10.64898/2025.12.12.694017v1

A preprint from my lab @yalepharm.bsky.social: doi.org/10.1101/2025... show molecular mechanisms of uncoupling nociceptive and neurotrophic TrkA signaling, using #singleMolecule #microscopy, #cryoEM, #electrophysiology, #signaling, offering a clear blueprint to target this long sought-after pathway!

I am so excited to share our newest preprint, inspired by @tinalonsdorf.bsky.social, “A multiverse approach to heat-evoked skin conductance analysis: Evaluating the influence of analytic pipeline on associations between skin conductance and pain osf.io/preprints/ps...

Canada is finally getting high speed rail (maybe?) But the route cuts out Kingston and leaves out London & Windsor. These could easily become engines of industry & exchange. What a missed opportunity! #Canada #CanPoli #politics #highspeedrail

Delighted to share our latest article on brain mechanisms of pain, appetitive & aversive learning, led by @yilizhao.bsky.social & In-seon Lee, out now in @sfnjournals.bsky.social! We show that brain mechanisms of expectancy are domain general, not unique to pain! www.jneurosci.org/content/earl...

another home for your pain manuscripts is in this special issue of European Journal of Neuroscience, led by @paulgeha.bsky.social and Susanne Becker onlinelibrary.wiley.com/page/journal...

pain people: not sure what to do with your last few weeks of 2025? write a paper and submit it for one of our special issues at Neurobiology of Pain: www.sciencedirect.com/journal/neur...

Come to Canada

Come to Canada

If you are an MRI researcher interested in moving to 🇨🇦 for $500k a year or $1M a year for 8 years with a possibility of renewal at a reduced rate, take a look at our equipment cfmm.uwo.ca and this program www.canada.ca/en/impact-pl... . MSK, neuroscience, cardiac, cancer applications all encouraged!

𝗪𝗵𝗮𝘁 𝗮𝗿𝗲 𝗯𝗿𝗮𝗶𝗻 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀? Do they even exist...? Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon. Open to all. Date: Dec 9, 12pm EST-US Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free) #neuroskyence

Everyone feels pain. Few understand it. @westernu.ca researchers are tackling its complexity with ambitious, cross-disciplinary science. "This is one of the best neuroimaging centres in Canada. I'm excited to see what we can build," says @daspainbrain.bsky.social. Read more in Rapport Magazine.

Join us for Fall 2026. In our group, you can run studies from human behavior and neuroimaging, to large-scale NHP ephys, and join them up with a robust computational foundation. Bonus: you can help build the reading list.

Our first endeavour in understanding how endogenous cannabinoids (eCBs) contribute to pain sensitivity. in @painthejournal.bsky.social. We found that baseline, fasted eCB ligands are not associated with point estimates of pain sensitivity, except for pressure pain. journals.lww.com/pain/fulltex...

🚨 New Job Alert in Our Lab! We’re hiring a full-time Research Assistant/Technician with experience in rodent stereotaxic surgery 🧠 and behavioral testing 🐁. Please help us spread the word! 🔗 Apply: umb.taleo.net/careersectio... @umsomneurosci.bsky.social @um-mind.bsky.social

Making history as the first nurse-clinician scientist honoured with a Gairdner Award, Jennifer Stinson used her acceptance speech to inspire the next generation. “Don’t just study science. Find a problem that connects your unique skills to a greater human need.”

The role of the #SpinalCord in relaying brain-body signals has been hard to study noninvasively. @giuliog.bsky.social &co develop Electrical Spinal Imaging (ESI), enabling high-resolution, noninvasive recordings, revealing how #attention modulates spinal activity @plosbiology.org 🧪 plos.io/3MswZOf

@massih.bsky.social et al. assert that identifying pain-specific processes requires salience-matching noxious and control stimuli. Salience ratings fully mediate stimulus intensity and physiological arousal relationship, demonstrating adequacy for matching. #PAIN bit.ly/3LuWKgq

Today on the #projectEPIC blog Veronica de Souza Campos and Daniel De Luca-Noronha discuss the Case of Chronic Pain Reports #philsky #epistemicinjustice epistemicinjusticeinhealthcareproject.blogspot.com/2025/11/epis...

Have you been wondering what the role is of non-neuronal cells in modulating sensory neuron activity? Check out this review from @psalmotoxin.bsky.social et al. in @sfnjournals.bsky.social’s #JNeurosci, one of this week’s #EditorsPick papers chosen by @rpseal.bsky.social bit.ly/3XEp2rE #P#JNeurosci#EditorsPick

humanfactors.jmir.org/2025/1/e80269 Check out our latest paper using natural language processing to study chronic pain narratives

🎙️Episode 2, Part 2: Why Do We Need an EDID Lens in Pain Research? Inclusive Language, Structural Violence, and the Power of Community Check it out and subscribe to #LivingProofPodcast on your favourite platform: 🔗YOUTUBE: shorturl.at/TnwVC 🔗SPOTIFY: shorturl.at/ovpHX 🔗APPLE: shorturl.at/S0P8v

Get a sneak peak of what we’ll chat about here: youtu.be/t0cTs3hi7JE?...

And the next step? Full voxel-level modeling. Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are. arxiv.org/abs/2511.12825

Opioid receptor distribution in the claustrum-dorsal endopiriform complex https://www.biorxiv.org/content/10.1101/2025.11.18.687877v1

The second study, led by @matthewcormie.bsky.social shows, for the first time, that the thermal grill can drive peripheral and central sensitization, but not tactile allodynia. journals.lww.com/pain/abstrac... Let us know what you think of this work!!

Our lab has 2 new papers in the current issue of @painthejournal.bsky.social: The first study, by Georgia Hadjis, shows that motivational conflict, rather than resource competition, determines priority assignment when pain is concurrent to competing demands. journals.lww.com/pain/fulltex...

#WesternU researchers have unlocked the hidden potential in discarded MRI data, developing a new technique transforming how scientists study the brain. @schulichmeddent.bsky.social

Interested in paediatric pain? Come and follow the Pediatric Pain Letter, an open access international publication which hears from researchers, clinicians, individuals with lived experience and other non academic voices. We would love to hear from you. Follow us here bsky.app/profile/pedi...

excited to be hosting Marco Loggia today as our @westernknowpain.bsky.social guest

Our lab is hiring! We're lookgin for an MSc trainee and a PhD trainee to investigate the neural underpinnings of pain. If you are interested in pain and brain imaging, please reach out! Informal enquiries are encouraged.

it's nice having smart colleagues who develop new tools. this one will be fun to use. pain in the SASS, here we come!

Excited to share our manuscript about BrainEffeX, a tool for exploring fMRI effect sizes. Includes why we made it, how to use it + contribute, and how we made it. @sneuroble.bsky.social @psychonetrics.bsky.social @alexkfischbach.bsky.social @nichols.bsky.social @dscheinost.bsky.social & MINDS Lab

14 months after submission, our article “Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI" is now out in @natmethods.nature.com . You can read it here rdcu.be/ePJo6 It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N

Come join us @westernu.ca @schulichmeddent.bsky.social as Canada Research Chair (CRC) Tier 2 in Cancer Biotherapeutics: uwo.ca/facultyrelat... DM me with questions. As a CRC 2 recruit to ACB, I highly recommend it!

In 1956, Jim Watson told my father, a brown man, that he would never get a job at Harvard and it was a miracle he had been admitted . Harvard's Board of Trustees saw it differently & appointed dad as an Assistant Professor and Director of the Harvard Agassiz Observatory BEFORE he finished his Ph.D!

Check out our newest demonstrating feasabilty of sub-mm whole brain EEG-fMRI at 7T. Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.

The BIG DRG paper is now up on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1... so many people worked so hard to make this happen. Props to the whole PRECISION Human Pain Network.