Blocking RAN translation without altering repeat #RNAs rescues C9ORF72-related #ALS and #FTD phenotypes | Science www.science.org/doi/10.1126/...

In light of Trump’s post yesterday, some history: “On Memorial Day 1927, 1,000 white-robed Klansmen marched through the Jamaica neighborhood, eventually spurring an all-out brawl in which seven men were arrested. One of those arrested was Fred Trump.” www.washingtonpost.com/news/the-fix...

Graduate Students’ NSF Fellowship Applications Are Being “Returned Without Review” 🧪 eos.org/research-and...

NBC editing out the booing of JD Vance is a disgrace. It’s an international event. Americans have the right to know what the world is saying. NBC has bowed down to Trump.

But “science is doing ok!”

"...as F.B.I. agents equipped with a signed warrant prepared to document blood spatter and bullet holes in Ms. Good’s S.U.V., they received orders to stop...." www.nytimes.com/2026/02/07/u...

That is exactly the point that should never be glossed over by any sane mind: "Anything A president SAYS is SERIOUS!"

So, how are black Republicans responding to recent truth social posts?

Though fearsome predators, snakes can go weeks or even months without eating. Now, scientists think they may know how they do it. Learn more: https://scim.ag/49ZcLFr

#Neural population #geometry and optimal #coding of tasks with shared latent structure doi.org/10.1038/s415...

But Bezos had $75 million to spend on Melania’s vanity project.

So now ICE is a Praetorian Guard for Trump to end free and fair elections? That's Bannon's scheme.

Jeff Bezos took over the Washington Post Editorial Board and turned it into a mouthpiece for pro-corporate, pro-billionaire propaganda. Now, WaPo is laying off hundreds of *real* journalists — including the reporter covering Amazon. Democracy dies in billionaire hands.

I do appreciate a good quantitative data set. Let me do some statistical analysis... Oh wait, no need. It is effing obvious what is going on.

The #orbitofrontal #cortex updates #beliefs for state #inference: Neuron www.cell.com/neuron/fullt...

Distinct roles of #prefrontal subregion feedback to the primary #visual #cortex across #behavioral states: Neuron www.cell.com/neuron/fullt...

Establishing the relationship between #brain cellular #senescence and brain structure: Cell www.cell.com/cell/fulltex...

These are the curves for new and competitive renewal grants. The number of new awards is increasing slightly, but only slightly. 17 out of 25 institutes and centers with funding authority have now made awards. 3/4

My weekly update on NIH funding. This is for all projects. The breakdown for competing and non-competing awards will follow. 1/4

I didn't even know somatodendritic dopamine release was a thing! #α-Synuclein expression is required for somatodendritic #dopamine release and immediate early #gene induction | Science Advances www.science.org/doi/10.1126/...

I’m Beginning To Think We Are Witnessing The Largest Criminal Enterprise Ever Created….

The bureaucracy of science has grown so much, the system is collapsing upon itself: Scientists have become administrators of grants rather than spending time on science. Paid administrators are demanding even more administrative work from scientists. Administrators are eating the science budget.

Outrageous Ofc, Bhattacharya quietly replaced the chief of the NIH’s environmental health institute with Kyle Walsh—a close buddy of JD Vance—without following standard NIH hiring practices like using a search committee, including external scientists, & interviewing multiple candidates Cronyism 😢

Luke Ganger, Renee Good’s brother: “In the last few weeks, our family took some consolation thinking that perhaps ‘Nee’s death would bring about change in our country. It has not.”

BALDWIN: Is it true you ended longstanding practice of including external scientists as part of director search committees? BHATTACHARYA: Senator, I've been working very har-- Q: Is it true? BHATTACHARYA: We've changed the process so that there's no formal committee bc we don't have time for it

Larkum really loves his cortical layer theories. Interesting though! The layer 6b theory of #attention: Neuron www.cell.com/neuron/fullt...

#Hippocampal #estrogen levels, receptor types, and #epigenetics contribute to #sex-specific #memory vulnerabilities to concurrent acute #stresses: Neuron www.cell.com/neuron/fullt...

Converging #dopamine pathways onto basolateral #amygdala #neurons encode exploration #decisions: Neuron www.cell.com/neuron/fullt...

Interesting, but I feel like this needs to be replicated. Identification of an #engram #ensemble mediating #memory #forgetting in the #dentategyrus: Neuron www.cell.com/neuron/fullt...

happening this morning in Minneapolis -- ICE agents drawing guns on observers. I reiterate again that it is only a matter of time before DHS kills more innocent people in Minnesota. Congress needs to shut this shit down right now.

Why don’t neural networks learn all at once, but instead progress from simple to complex solutions? And what does “simple” even mean across different neural network architectures? Sharing our new paper @iclr_conf led by Yedi Zhang with Peter Latham arxiv.org/abs/2512.20607

Molecular features of #human pathological #tau distinguish tauopathy-associated #dementias: Cell www.cell.com/cell/fulltex...

"I scheduled meetings often and left limited time for them to read and think... when their progress was slower than expected... didn’t show empathy and understanding. I pushed them relentlessly... This went on for years." www.science.org/content/arti...

Congrats to @aaronsalisbury.bsky.social and @mictott.bsky.social on this exciting project initially designed to mechanistically investigate a molecular association with PTSD that we observed in postmortem human brain tissue. Fun🧵below explaining the scientific rational and findings from Michael!

Astrocytes mediate a positive feedback loop for oxytocin https://www.biorxiv.org/content/10.64898/2026.02.02.699227v1

Cerebellar circuits anticipate dopamine rewards https://www.biorxiv.org/content/10.64898/2026.02.02.703324v1

DHS said that the woman CBP shot in the chest in Portland was “involved” in a gang shooting. Her ~involvement~ was that suspected gang members sexually assaulted and robbed her.

Maybe Paramount should cut ties with Bari Weiss. Just sayin'

This is a post about animal excrement and the English language. bull$#!% = nonsense/lies chicken$#!% = petty or cowardly horse$#!% = nonsense/lies dog$#!%= low quality ape$#!% = wild bat$#!%= crazy Ordered above from oldest to newest: bull$#!% (1914), bat$#!% (1971).

What do POS people feel when they watch movies or read books? Do they root for the villains? Do they get upset that, at least in these stories, the villains typically lose? Or do they somehow align themselves with the heroes and, by some mechanisms, feel no cognitive dissonance?

If a university student group had celebrated Charlie Kirk being killed, complete with a graphic made from an actual picture of the killing, the whole lot of them would have been expelled before the ink on the digital story was dry.

Trump's lawless detention policies + Kennedy's eugenicism creating a dangerous domestic/global Measles superspreader event..... www.sacurrent.com/news/san-ant...

It’s 2026. There is a measles outbreak in the prison for babies

Oh shit, I was looking at some of the Epstein files and saw an image that wasn't completely redacted... and now I don't think I'm gonna fall asleep tonight.

Liam, 5, has been freed, but four other students from his school district remain detained in Texas. Two boys from his elementary school were taken Thurs “This isn’t something we are prepared or trained for. We’ve dedicated our lives to protecting + educating children,” school superintendent told me

What a nightmare. “After a week of public outcry over the South Texas Family Residential Center’s treatment of young children behind its walls, the Dilley facility is experiencing a measles outbreak, according to immigration attorney Eric Lee.” @jackiantonovich.bsky.social

ProPublica identifies Pretti's killers