So, armed with the latest molecular biology techniques, we're going to learn about the effects of cosmic radiation & microgravity in a way that cannot be replicated on Earth. These experiments can help guide future protective protocols, but also might reveal some new mysteries to explore!

Let's learn about some medical research that just left Earth on Artemis II, bound for the silver sphere in the sky. It's AVATAR, but it doesn't involve blue aliens. It stands for "A Virtual Astronaut Tissue Analog Response" & it looks like this USB drive-sized device.

Welp this is one of the coolest things I've ever seen.

🧠 Focused ultrasound changes emotional processing 🔊 In a new study published in Neuron today, we stimulated the human amygdala using transcranial ultrasound stimulation (TUS) and show it plays a causal role in detecting and resolving emotional ambiguity.

"we developed a single-cell four-omics sequencing method that enables parallel profiling of genome conformation, histone modifications, chromatin accessibility and gene expression" doi.org/10.1038/s415...

SR2P: an efficient stacking method to predict #protein abundance from #gene expression in #spatialtranscriptomics data doi.org/10.64898/202...

Cell type composition drives patient stratification in single-cell RNA-seq cohorts #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.03.27.714811v1

I mean there it is.

#Thalamic activation of the #visual #cortex at the single- #synapse level | Science www.science.org/doi/10.1126/...

A #genetically encoded device for #transcriptome #storage in #mammalian #cells | Science www.science.org/doi/10.1126/...

A cosmic first! 🚨 Hubble has spotted a comet that slowed and reversed its spin. Outgassing jets acted like thrusters, literally pushing it into a new rotation, shown here in this science visualization: https://news.stsci.edu/4c2u6hv

Dendritic excitatory-inhibitory balance and branch-specific gating enable selective recall of associative memories https://www.biorxiv.org/content/10.64898/2026.03.27.714865v1

LeWorldModel: Stable End-to-End Joint-Embedding Predictive Architecture from Pixels youtube.com/watch?v=-k4n...

A new paper in Science measured the prevalence of social sycophancy across 11 leading large language models. The model’s responses were nearly 50% more sycophantic than humans’, even when users engaged in unethical, illegal, or harmful behaviors. www.science.org/doi/10.1126/...

Happy #FluorescenceFriday! This is a confocal 🔬 series of a developing 🐭 spinal cord showing nuclei, actin, and cellular membrane stains colored in 🌈 Microscopy by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪

From Meta: "TRIBE v2 reliably predicts high-resolution fMRI brain activity — enabling zero-shot predictions for new subjects, languages, and tasks — and consistently outperforms standard modeling approaches." ai.meta.com/blog/tribe-v...

Never ask a question to which you are unprepared to hear an honest answer.

Two-photon calcium imaging at 24,000 lines/s, with the resonant axis spanning 4x what other systems can do. Inertia-free. Diffraction-limited. No tradeoffs. Che-Hang Yu developed a 4x angle multiplier for laser scanning. His paper is out today: opg.optica.org/optica/fullt... 1/n #fluorescenceFriday

In the summer of 2004, Douglas Baird was leading excavations at a remote hunter-gatherer site called Pınarbaşı in central Turkey when his team found something unusual... @science.org

👁️🐦 Birds experience a far richer visual world than we do. While humans are trichromats—seeing blue, green, and red—most birds are tetrachromats, able to detect an extra channel: ultraviolet (UV). They spot patterns and colors completely invisible to us. Read on👇 earthlymission.com/human-vision...

Our NIAAA funded Post-DoctT32 has received its NoA (non competing renewal). Are you looking for a post-doc and interested in joining our amazing center? If so, reach out! Here is a convenient form that you can use to upload CV and a cover letter! unc.az1.qualtrics.com/jfe/form/SV_...

Fascinating! A 20 yr study into cloning has revealed a fundamental flaw. Repeated duplication leads to an accumulation of fatal genetic mutations. Researchers in Japan generated 1,206 cloned mice from a single female donor between 2005 & 2025. 🧪 www.independent.co.uk/news/science...

"Here, we expand Tabula Sapiens to the non-coding transcriptome with single-cell and single-nucleus total RNA sequencing across 22 human organs and tissues" www.biorxiv.org/content/10.6...

The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution — a Review by Jeffrey J. Colgren & Pawel Burkhardt @jeffcolgren.bsky.social @pawelburkhardt.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...

Nature research paper: Functional hierarchy of the human neocortex across the lifespan go.nature.com/4t2Rh0N

Scientists at Los Alamos have engineered quantum processes that make time seem to run backward ⏳🔄. Discover how they're reshaping the quantum arrow of time and extracting energy from quantum systems. Read more: www.azoquantum.com/News.aspx?ne... #QuantumPhysics #ArrowOfTime

For the first time ever, antimatter will be transported out from a scientific laboratory. Regular deliveries planned. Interestingly, there are no regulations for antimatter transportation. It's not that you can do anything, - there is a road traffic regulation. www.nature.com/articles/d41...

Bhattacharya shouldn't be running the CDC, but he also shouldn't be running the NIH. "The halfway point of the federal fiscal year looms at month’s end, yet the National Institutes of Health has only obligated around 15[%] of the estimated $38 billion... 1/8 www.insidehighered.com/news/governm...

Super proud of @sjoerdmeijer.bsky.social who demonstrated that amygdala-TUS slows initial threat acquisition and enhances subsequent extinction. Great collaboration with @lennartverhagen.bsky.social and @deVoogdld.bsky.social ea. Thanks to @ERC.europa.eu. www.science.org/doi/10.1126/...

What could possibly go wrong? "The AI Scientist, which creates research ideas, writes code, runs experiments, plots and analyses data, writes the entire scientific manuscript, and performs its own peer review" www.nature.com/articles/s41...

Very excited to share that I’m starting my lab at the Krembil Brain Institute @kbi-uhn.bsky.social at UHN and the University of Toronto! If you’re interested in motor learning and circuit plasticity, please reach out - we are hiring! www.motor-plasticity.org 1/

AAV vector development, back to the future: Molecular Therapy www.cell.com/molecular-th...

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

hope everyone’s stocked up on lab plastics — pipette tips, centrifuge tubes, cell culture dishes…..

GPCRs as Targets for Human Brain Modulation: A Multi-omic Atlas of Cell-Type Specific Expression https://www.biorxiv.org/content/10.64898/2026.03.23.713764v1

Engineered tissue offers hope for babies born with missing food pipe section #NBTintheNews www.ucl.ac.uk/news/2026/ma...

Paternal behavior is controlled by preoptic Trpc5 neurons https://www.biorxiv.org/content/10.64898/2026.03.20.713203v1

Synaptic dynamics as a tunable substrate shaping neuronal activity sequences https://www.biorxiv.org/content/10.64898/2026.03.22.713064v1

Inter-individual variation of cellular and gene-expression properties of the human striatum https://www.biorxiv.org/content/10.64898/2026.03.20.713160v1

Neuroscience has become increasingly concerned with prediction, and machine learning with causal explanation, with each field adopting methods from the other, writes @gershbrain.bsky.social. Will this bring us closer to understanding neural systems? www.thetransmitter.org/the-big-pict...

*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!

Email your senators to urge them not to confirm Jim O’Neill as Director of the National Science Foundation. He's not a scientist, has no relevant expertise, promoted vaccine misinformation, helped gut the CDC, and his Silicon Valley ties raise questions about protecting the public interest. (1/2🧵)

#Synthetic #circuits for #cell ratio control www.nature.com/articles/s41...

Adaptive evolution of gene regulatory networks in mammalian neocortex www.nature.com/articles/s41... - very interesting work from Nenad Sestan and colleagues...

Jerome Powell, President of the FED: "Job gains have remained low. Inflation remains elevated" "High inflation largely reflects the price of goods, mainly due to tariffs" "Short-term inflation expectations have risen in recent weeks due to the situation in the Middle East"

If true, this would reflect the informal data from the numbers of people I know who are looking for work. Orgs and companies are not hiring...

Excited to share my postdoc work is out in @natneuro.nature.com today! We examined how the brain enables social groups to collectively coordinate their behavior in the face of environmental challenge ❄️🐭🐭🐭🐭❄️ : www.nature.com/articles/s41...

Regional specialization in #prefrontal #cortex manifests in the reliability of task progression #codes: Neuron www.cell.com/neuron/fullt...