New online! Gut–brain communication: types of sensory nerves and mechanisms of activation

We’re offering free vaccine clinics in Boston. Vaccines are safe, effective, and protect against serious illness. Getting vaccinated keeps you healthy and helps protect your family, friends, and community. Find upcoming vaccine clinics at boston.gov/vaccine-clinics.

“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances: doi.org/10.1126/scia...

🧪📣The final version of our latest paper is out!!🤗 "Metainflammation alters neutrophil function and migration in vivo in response to tissue injury" Go check it out in case you haven't yet😉🔬🐟 #zebrafish #neutrophils #injury #microscopy #metainflammation #MetabolicSyndrome

Not your everyday view! #Zebrafish #Research ❤️

More beautiful biology! Z-stack maximum projection confocal image of a section of the cow #cerebellum. Magenta: neurofilament heavy chain, green: actin, blue: DAPI #Axons #microscopy #biology #science

Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...

Awesome work from the Lempradl lab showcasing the precise regulation of metabolism during embryogenesis in our fruit fly friends!

Article by @cenmag.bsky.social on the #BethesdaDeclaration by NIH scientists and staff released earlier this morning: cen.acs.org/policy/resea...

I love my lab so much 😭❤️🥹 feel so lucky

Hello Fly Folks. quick note FlyBase is under duress due to termination NIH$ to Harvard and intl collabs. The hardworking folks @flybase.bsky.social are doing their darndest to ensure access to current data. For US, there will soon be a new site to donate. Please spread the word, ideas and support 🪰💪

Lyft driver picked me up from UNC, turned out he was a medicinal chemistry post-doc in a building near mine, until his grant got cut last month. Worked on novel antivirals.

“I would like to cure brain cancer. I think that's not particularly controversial.” Be that as it may, the NIH terminated that scientist's grant. Here's a huge survey of the 2,500 grants that NIH has killed or delayed...so far. Gift link: nyti.ms/43Jz1yJ

13-yr-old Camarria Williams made a remarkable discovery when she found a compound with potential cancer-fighting properties in goose poop from Garfield Park, Chicago. This surprising find happened while participating in the Chicago Antibiotic Discovery Lab, a STEM program in collaboration with the

The gutting of US biomedical research with loss of ~2,500 grants affecting research for cancer, Alzheimer’s, infectious disease, global health and much more www.nytimes.com/interactive/...

The #Drosophila community can donate to the European side to save FlyBase @flybase.bsky.social at the following link: www.philanthropy.cam.ac.uk/give-to-camb...

To dissect the gene regulatory networks used to build organisms, we need Perturb-seq-like tools that work in whole animals. For this purpose, we developed MIC-Drop-seq, a tool that couples high-throughput CRISPR in zebrafish embryos with single-cell RNAseq. www.biorxiv.org/content/10.1...

I urge everyone to read Unbreaking’s new page on everything the govt is doing to destroy & diminish medical research funding. It’s the best thing I’ve read on this topic: @lizneeley.bsky.social & co have such done an incredible job. unbreaking.org/issues/medic...

Out now in #Science #Immunology: Christopher Hall & colleagues at @aucklanduni.bsky.social report in #zebrafish that the #circadian clock gene per2 boosts daytime #antibacterial activity in #neutrophils by promoting infection-responsive hmgb1a expression!

Trump’s proposed $23 billion in cuts to NIH & NSF could cost the U.S. economy at least $10 billion a year, according to new research. Public science funding drives innovation, productivity, and long-term growth. Slashing it isn’t saving money; it’s losing our future. www.forbes.com/sites/johndr...

My ongoing request: If your NSF or NIH grant was terminated--whether at Harvard or elsewhere--please report it here. NSF: grant-watch.us/submit-nsf.h... NIH: grant-watch.us/submit-nih.h... Our trackers are actively used in lawsuits and are often the only record that terminations ever occurred.

My Bioinformatics Bootcamp turned blog! Enjoy this collection of free #zebrafish resources, now posted on @the-node.bsky.social. While not comprehensive, it gives an assortment of cools tools available to researchers. Feedback would be appreciated! thenode.biologists.com/bioinformati...

NSF just cancelled ALL grants to Harvard researchers. That’s right - physics, astronomy, bio, CAREER - ALL. Professors won’t get paid. Postdocs won’t get paid. PhD students won’t get paid. This is insane! If they can do this to Harvard, they can do this to your school.

A review emphasizes the advantages of using zebrafish in research, outlines key differences in experimental approaches, and offers guidelines for designing studies in a way that enhances experimental rigor and reproducibility. www.nature.com/articles/s42...

I find it so beautiful, that moment when you’re deep in a conversation about science, exploring the unknown, and everyone brings their own ideas about things that are not yet known, built on what we do know. There’s something profoundly mesmerizing in imagining realities together.

I'm very excited to share our latest work with #zebrafish published in @mucosalimmunol.bsky.social!! 🐟 www.sciencedirect.com/science/arti... Here, we characterized a genetic model of intestinal epithelial cell ablation to study the cellular and molecular mechanisms of intestinal #regeneration....

Clinical isolate of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 eats plastic used in IV and urinary catheters PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source Worse yet—the plastic diet enhances biofilm formation 𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎 www.cell.com/cell-reports...

My buddy @karenecheverri.bsky.social just published her latest (with a minor assist from yours truly) on how tail regeneration in #axolotls relies on brain activity. Specifically neurons in the telencephalon that project to the hypothalamus. #regeneration #cutemascot www.nature.com/articles/s41...

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

#zebrafish Does anyone stateside have a ubi:mRFP-CAAX line? Thanks!

Proposed Trump budget caps NSF indirect cost payments to universities at 15% www.washingtonpost.com/politics/202...

Budget released today: 40% cut to NIH 50% cut to NSF If enacted, this will destroy academic research in the United States. It will also have a major trickle down effect on the entire academic ecosystem

This is catastrophic and everything, within and outside the US, should be protesting loud and clear

This issue has become more acute in recent years. A narrow view of "mechanistic" experiments holds us back. "A case for broadening our view of mechanism in developmental biology" journals.biologists.com/dev/article/...

I’ve always known that doing science is an incredible privilege. But these days, it’s insane. Thank you to everyone who applied to my job posting. I saw so many talented, hardworking people. The position is now filled, but I truly wish I could have hired more. I hope for better times for all of us.

More flavors please

Neurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress https://go.nature.com/4lP2EHa

NIH cancels its first and largest study centered on women www.science.org/content/arti...

What are the 3D spatial molecular patterns of differentiating enteric nervous system (ENS) in vivo? Are there co-expression networks? Are there spatially variable genes? In our preprint www.biorxiv.org/content/10.1... @RodrigoMoreC et al explored 1/4

2. The shocking damage at NSF. New awards are frozen. Approved awards have been sent back for more review. www.science.org/content/arti... Worse, starting yesterday afternoon, hundreds of active grants are being terminated, especially DEI & mis/disinformation work www.nature.com/articles/d41...

I got an email yesterday afternoon that my NSF SPRF Postdoctoral Fellowship was terminated. My grant focused on testing interventions to address online misinformation and I was 8 months into a two year appointment.

📢 Fresh off the press and featuring new exciting experiments! 🧪 We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊 doi.org/10.1016/j.st... B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

Watch as we inject morpholinos into zebrafish embryos to knockdown gene expression! 🦓🐟😍 #ZebrafishRock #GeneticResearch #Knockdown #ScienceInAction @zebrafishrock.bsky.social

Director of the Nat'l Institute of Child Health and Human Development (NICHD) was summarily dismissed yesterday. So here's your reminder that birth defects kill twice as many American kids as cancer. But there is no St. Jude's for birth defects. Only the NICHD. www.nature.com/articles/d41...

Illumina announced the discontinuation of the old MiSeq, MiniSeq and old i100 instruments.

The brain’s energy landscape as a potential window into brain health www.nature.com/articles/d41... (study led by Martin Picard and Michel Thiebaut de Schotten)

In <24 hours, Covid funding is DOGEd across HHS, CDC, NIH as if it and Long Covid didn't exist and there is no worry for future pandemics www.science.org/content/arti... www.nbcnews.com/health/healt... www.science.org/content/arti...

Royal Society decides not to take disciplinary action against Elon Musk