This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!

Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels? Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202... Thread below 🧵

Happy to share this early Christmas present 🎄: our paper about geometry- and locomotion-dependence of 3D memory got published in PNAS! Joint work with co-first-author Volker Reisner (@reisnerv.bsky.social) as well as Leonard König, Misun Kim & Christian Doeller www.pnas.org/doi/10.1073/

Absolutely agree. The genetic makeup of a species does explain what sets it apart from other species, but the explanation is usually complex, and not reducable to the isolated effects of single variants. IMO, this work provides further evidence for the existing view of combinatorial evolution.

fMRI signals “up,” but neural metabolism might be going “down.” In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes. rdcu.be/eUPO8 funds @erc.europa.eu #neuroskyence 🧵:

🧠New preprint! What if cortical geometry alone already encodes much of white-matter organization? We introduce a subject-specific, reversible cortical folding model that unfolds and refolds the brain from a single T1w MRI; no diffusion, no ML. www.biorxiv.org/content/10.6...

I am so excited to share our newest preprint, inspired by @tinalonsdorf.bsky.social, “A multiverse approach to heat-evoked skin conductance analysis: Evaluating the influence of analytic pipeline on associations between skin conductance and pain osf.io/preprints/ps...

Dimensionality reduction may be the wrong approach to understanding neural representations. Our new paper shows that across human visual cortex, dimensionality is unbounded and scales with dataset size—we show this across nearly four orders of magnitude. journals.plos.org/ploscompbiol...

Only a few weeks left to apply for our 4-year PhD position, using human brain organoids & multi-omic methods to study genes implicated in speech disorders. Application deadline 5 Jan 2026. Fellowship is embedded in the International Max Planck Research School. More info: www.mpi.nl/imprs-phd-fe...

Very thoughtful thread on why it matters to compute the right noise ceiling & why communication is so important to prevent this issue from spreading. Kudos to Sam for being so transparent! In brief: NC for best R^2 == data reliability expressed as r NC for best r == sqrt(reliability)

1/ Our new paper is out in Imaging Neuroscience! 🎉 We validated in-vivo MRI–based axon radius mapping by comparison to large-scale human brain histology (> 46 M axons & 35 CC-ROIs). Title: “MRI-scale histology validates spatial sensitivity of in-vivo MRI-based axon radius estimation”

New paper in Imaging Neuroscience by Laurin Mordhorst, Siawoosh Mohammadi, et al: MRI-scale histology validates spatial sensitivity of in-vivo MRI-based axon radius estimation doi.org/10.1162/IMAG...

Disabled people deserve healthcare. Disabled people deserve housing. Disabled people deserve food. Disabled people deserve support. Our ability to work and produce should not determine our value. Disability is not a moral failing. Most people will experience it someday.

Diederik Stapel was a massive watershed moment in psychology. However, he was -- and let's be slightly glib here -- some guy from The Netherlands who wrote social psychology papers. The full accounting of the Eysenck case is approx, at minimum, TWO STAPELS. retractionwatch.com/2025/12/03/n...

Thread of French and Dutch research institutes slowly unsubscribing from web of science (and thence impact factors).

How does the brain integrate visual and somatosensory representations? A recent @nature.com paper presents a model that, when applied to ongoing co-activations during rest, results in detailed maps of body-part tuning that aligns with visual tuning 🧪 Read more here: www.nature.com/articles/s41...

This is an amazing success story. We are happy to have published several papers there - it really has become the top neuroimaging journal within just two years. Kudos to all who had the courage to make it happen!

Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧵 on our @science.org paper.🧪1/n

Excited to share that the main work of my PhD has been published! We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC. You can read the full version of the paper here: rdcu.be/eQy6X

Please share! - 🚨⚠️ PhD position alert ⚠️🚨 - Please share! Come work with @ldeserno.bsky.social and yours truly on an exciting DFG-funded project on the neurocognitive mechanisms of (noise in) learning and decision-making in development and ADHD!

And the next step? Full voxel-level modeling. Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are. arxiv.org/abs/2511.12825

New paper in EBioMedicine! We analyzed EEG from 614 people with chronic pain across 5 countries. Standard EEG biomarkers didn’t replicate, but network connectivity (esp. theta) shows promise. Open access: tinyurl.com/yc599257

New preprint from the lab on stroke and oscillations detected via ultrafast fMRI! www.biorxiv.org/content/10.1...

Bug in Springer Nature metadata may be causing ‘significant, systemic’ citation inflation

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com www.nature.com/articles/s41...

This is 🤯 All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool. #neuroskyence #mri #brainmapping A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...

Interested in how we make preference-driven decisions, and how this is implemented in the brain? We report that neural correlates of evidence accumulation (CPP, Mu/Beta) are also observed during value-based decisions. www.biorxiv.org/content/10.1... Led by @laurencf.bsky.social (Lauren Fong) 1/n

Please repost! I am looking for a PhD candidate in the area of Computational Cognitive Neuroscience to start in early 2026. The position is funded as part of the Excellence Cluster "The Adaptive Mind" at @jlugiessen.bsky.social. Please apply here until Nov 25: www.uni-giessen.de/de/ueber-uns...

🚀 We are hiring! 🚀 🔍 Join us as a Postdoctoral Researcher (fully-funded) at the Helmholtz Institute for Human-Centered AI in Munich.

Stoked to see our study out in final form! Big kudos to @jonathanamichaels.bsky.social for driving this along for the past 5 years.

More than two decades have passed since we discovered that rare disruptions of the FOXP2 gene disturb development of proficient speech/language skills. Today we know of multiple FOXP genes that are directly implicated in distinct brain-related conditions with differences in symptoms & severity.🧪 1/n

If you use the Monetary Incentive Delay task or any task with complex events in fMRI, you should read this. We demonstrate that common modeling approaches can result in bias due to omitted variables. By @jeanette-mumford.bsky.social & the ABCD task fMRI team. direct.mit.edu/imag/article...

📘🧠💥@fabianrenz.bsky.social , @nicoschuck.bsky.social & I thought about methods to measure brain plasticity and wrote an overview of exciting new methods and developments! Read our chapter, out now in The Oxford Handbook of Cognitive Enhancement and Brain Plasticity academic.oup.com/edited-volum...

Psychedelics alter neurovascular coupling, which means we need to critically re-evaluate fMRI findings of acute psychedelic effects #neuroskyence #PsychSciSky www.nature.com/articles/s41...

Of course most exciting for me: cytoarchitectonic proof that the VIM exists (and is not a subunit of VL as implied by the Jones nomenclature).

Variability in #NeuralActivity is associated with cognition, but how does it relate to pain? @li-bo-zhang.bsky.social &co show that neural variability correlates with how individuals perceive #pain intensity in different contexts @plosbiology.org 🧪 plos.io/48QPR2S

🚀 We’re hiring - Join our lab 🚀 🔍 Hiring: PhD (75% TV-L) & Postdoc (100% TV-L) 🧠 fMRI, VR, EEG, modelling We combine a range of cognitive neuroscience methods to study flexible behaviour. 📅 Start: Feb 2026 or later | ⏳ Apply by Nov 3! More details: tinyurl.com/ms3a9ajt #CognitiveNeuroscience

Come join us for a 4-year PhD on effects of rare gene disruptions involved in speech disorder, investigated in human neuronal models (via gene-editing, tissue culture, brain organoids, high-res microscopy, transcriptomics, epigenomics). More info: www.mpi.nl/imprs-phd-fe... #AcademicJobs #PhDJobs 🧬🧪

OPEN PHD POSITION - Come join our group! The IMPRS at @mpi-nl.bsky.social is offering an PhD position on modelling structured meaning in the brain, supervised by me and Helen De Hoop at the Centre for Language Studies in the @dondersinst.bsky.social - www.mpi.nl/imprs-phd-fe... #NeuroJobs #cogsci

Here is a chance for international undergraduates to come to Hamburg and work with the amazing @elbersgerd.bsky.social

Excited to announce that this is now out in eLife as a reviewed preprint 🚀 doi.org/10.7554/eLif... Huge thanks to the eLife editors, reviewers and our fantastic collaborators: Katharina Wille, @nicoschuck.bsky.social, Matt Nassar, Radoslaw Cichy, Peter Dayan and @rasmusbruckner.bsky.social

in which @lmesseri.bsky.social and @mjcrockett.bsky.social upend the increasingly pervasive premise of the LLM-fabricated human research subject (and the histories/ ideologies of cognition baked into the experimental "tasks" they're called upon to complete) at its epistemic roots

New paper in Imaging Neuroscience by Roza G. Bayrak, Catie Chang, et al: DeepPhysioRecon: Tracing peripheral physiology in low frequency fMRI dynamics doi.org/10.1162/IMAG...

How does the brain direct our #attention to conspicuous objects in our field of #vision? This study in humans maps the neural origin and propagation of #saliency signals through #CorticalLayers during visual processing @plosbiology.org 🧪 plos.io/4qqcAsW

New paper in Imaging Neuroscience by Jingyuan E. Chen, Jonathan R. Polimeni, et al: Differentiating BOLD and non-BOLD signals in fMRI time series using cross-cortical depth delay patterns doi.org/10.1162/IMAG...

OpenNeuro @openneuro.bsky.social just hit a huge milestone: 1500 datasets! Congrats to the team on making this project so successful over the last 7 years.

A speech about what drives me, how science and open source are bitter victories, unable to make improve the world if society does not embrace them for the better: gael-varoquaux.info/personnal/a-...

New paper alert! Rare DNA changes in the SETBP1 gene are linked to speech problems & diverse syndromes affecting brain development. Work led by ace postdoc @maggiemkwong.bsky.social uncovered impact of different gene variants, coupling clinical/speech evaluation to molecular & cellular readouts.🧬🗣️🔬🧪

In 2016 Hinton predicted that AI would replace all radiologists in five years. Ten years later, why hasn't it happened? This post is a great explainer. www.understandingai.org/p/ai-isnt-re...