Noam Shemesh
@shemesh-lab.bsky.social
📤 166
📥 271
📝 14
The ultrahigh field 18 Tesla
@brukercorporation.bsky.social
MRI Scanner has just arrived to
@champalimaudr.bsky.social
! Along with its cryoprobes, it is expected to be the most powerful preclinical scanner in the world. Ramping up will take time... will keep you posted!
7 days ago
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reposted by
Noam Shemesh
Champalimaud Research
9 days ago
@champalimaudf.bsky.social
just installed a custom-built 18-Tesla horizontal-bore MRI scanner – the strongest for in-vivo imaging – to advance preclinical research non-invasively in neuroscience and cancer. Full story:
shorturl.at/pGREa
#PreclinicalResearch
#Neuroscience
#Cancer
#MedicalImaging
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reposted by
Noam Shemesh
Serge Dumoulin
20 days ago
The paper demonstrating that
#psilocybin
alters contextual computations is out in
@natcomms.nature.com
:
doi.org/10.1038/s414...
Thanks to the reviewers and coauthors :
@marcoaqil.bsky.social
,
@tknapen.bsky.social
,
@gillesdehollander.bsky.social
, and Nina Vreugdenhil
add a skeleton here at some point
2
22
4
New preprint from the lab on stroke and oscillations detected via ultrafast fMRI!
www.biorxiv.org/content/10.1...
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Increased striatal coupling one week after ischemic stroke revealed by ultrafast functional MRI
Background: Network reorganization following ischemic stroke is thought to play a role in recovery. Although cortico-cortical reorganization is widely established, changes in interhemispheric striatal...
https://www.biorxiv.org/content/10.1101/2025.11.12.688149v1.full.pdf+html
29 days ago
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reposted by
Noam Shemesh
Alessandro Gozzi
about 1 month ago
Great coverage by
@thetransmissions.bsky.social
of our latest preprint: adding new evidence (and a hint of controversy 🙂) to the E/I imbalance debate in autism 👇👇
www.thetransmitter.org/spectrum/ram...
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Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.
https://www.thetransmitter.org/spectrum/ramping-up-cortical-activity-in-early-life-sparks-autism-like-behaviors-in-mice/
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reposted by
Noam Shemesh
Oded Rechavi
about 2 months ago
Unlike the heart attack of getting a “Decision” email, it’s such a good feeling to get a “Your review is ready” email from qed :)
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reposted by
Noam Shemesh
Oded Rechavi
about 2 months ago
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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reposted by
Noam Shemesh
Ravi Menon
about 2 months ago
Tried this on a very technical fMRI manuscript with neuroscience applications. It warned me that neuroses outside its core expertise, but then proceeded to present an amazing analysis of the claims in the paper. Vastly superior to ChatGPT for example. I am impressed!
add a skeleton here at some point
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reposted by
Noam Shemesh
Ravi Menon
2 months ago
The things we can do
@westernu.ca
thanks to platform support grant funding from
@braincanada.bsky.social
And
#NFRF
add a skeleton here at some point
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reposted by
Noam Shemesh
The Transmitter
3 months ago
Even though the controversial DIANA method didn’t pan out, neuroimaging researchers still hold out hope to one day measure neuronal activity using fMRI. By
@callimcflurry.bsky.social
www.thetransmitter.org/retraction/a...
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Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
https://www.thetransmitter.org/retraction/authors-retract-science-paper-on-controversial-fmri-method/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250926-news-rp-authors-retract-science-paper-on-fMRI-method
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reposted by
Noam Shemesh
Imaging Neuroscience
3 months ago
New paper in Imaging Neuroscience by Roza G. Bayrak, Catie Chang, et al: DeepPhysioRecon: Tracing peripheral physiology in low frequency fMRI dynamics
doi.org/10.1162/IMAG...
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reposted by
Noam Shemesh
Ravi Menon
3 months ago
A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks.
direct.mit.edu/imag/article...
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A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
Abstract. Mouse functional magnetic resonance imaging (fMRI) studies contribute significantly to basic fundamental and translational neuroscience research. Performing fMRI in awake mice could facilita...
https://direct.mit.edu/imag/article/doi/10.1162/IMAG.a.920/133259/A-non-invasive-approach-to-awake-mouse-fMRI
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reposted by
Noam Shemesh
Ravi Menon
3 months ago
Science is self correcting. Finally!
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Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
https://www.thetransmitter.org/retraction/authors-retract-science-paper-on-controversial-fmri-method/
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reposted by
Noam Shemesh
The Transmitter
3 months ago
A method for capturing neuronal activity using fMRI excited the neuroimaging field but couldn’t be replicated. Today, the authors of the original paper retracted their work. By
@callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/retraction/a...
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Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
https://www.thetransmitter.org/retraction/authors-retract-science-paper-on-controversial-fmri-method/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250925-news-authors-retract-science-paper-on-fMRI-method
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An important retraction of the DIANA paper. Scientific progress is often made by correcting prior efforts, and here the community played its part efficiently. While this particular form of mapping neural activity was unsuccessful, the search continues!
www.thetransmitter.org/retraction/a...
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Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
https://www.thetransmitter.org/retraction/authors-retract-science-paper-on-controversial-fmri-method/
3 months ago
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5
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reposted by
Noam Shemesh
Imaging Neuroscience
3 months ago
New paper in Imaging Neuroscience by Marie E. Galteau, Joanes Grandjean, et al: Activation mapping in multi-center retrospective rat sensory-evoked functional MRI datasets using a unified pipeline
doi.org/10.1162/IMAG...
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direct.mit.edu/imag/article...
NEW PAPER! After many years in the making... we present evidence that BOLD-fMRI can detect push-pull interactions in subcortical areas. Congrats to Frederico Severo and Mafalda Valente!
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Functional MRI reveals subcortical auditory push-pull interactions requiring intercollicular integrity
Abstract. The role of subcortical structures in binaural integration is of great interest for auditory processing. The inferior colliculus (IC) is the main auditory midbrain center where ascending and...
https://direct.mit.edu/imag/article/doi/10.1162/IMAG.a.155/132915/Functional-MRI-reveals-subcortical-auditory-push
3 months ago
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reposted by
Noam Shemesh
Ravi Menon
6 months ago
More fields need to do this.
add a skeleton here at some point
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10
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Another new paper from the Lab, with a multimodal fMRI / CBF / cFOS approach in an animal model of Parkinson's Disease! Congrats
@ruxandalungu.bsky.social
@ciscaff.bsky.social
, Sara Monteiro and our great collaborator Tiago Monteiro!
journals.sagepub.com/doi/10.1177/...
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Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
https://journals.sagepub.com/doi/10.1177/0271678X251338952
7 months ago
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reposted by
Noam Shemesh
Communications Biology
8 months ago
🧠👁️A SC push-pull interaction during the dynamic vision mode, revealed with fMRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mechanisms for avoiding visual blur during saccades.
@shemesh-lab.bsky.social
doi.org/10.1038/s420...
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Evidence for a push-pull interaction between superior colliculi in monocular dynamic vision mode - Communications Biology
A SC push-pull interaction during the dynamic vision mode, revealed with functional MRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mech...
https://doi.org/10.1038/s42003-025-08081-0
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new paper from the Lab, harnessing fMRI and lesions to reveal some interesting "push-pull" interactions in Superior Colliculus! Check it out here
www.nature.com/articles/s42...
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Evidence for a push-pull interaction between superior colliculi in monocular dynamic vision mode - Communications Biology
A SC push-pull interaction during the dynamic vision mode, revealed with functional MRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mech...
https://www.nature.com/articles/s42003-025-08081-0
8 months ago
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reposted by
Noam Shemesh
Ian Shih
9 months ago
1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-wide mapping in awake, behaving rodents. If this could be useful to your colleagues and friends, please help spread the word!
www.biorxiv.org/content/10.1...
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reposted by
Noam Shemesh
Uzay Emir
9 months ago
onlinelibrary.wiley.com/doi/full/10....
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Rosette Spectroscopic Imaging for Whole‐Brain Slab Metabolite Mapping at 7T: Acceleration Potential and Reproducibility
2D-/3D- whole-brain slab non-lipid-suppression ultra-short-TE 1H-MRSI acquisition schemes were developed using the rosette trajectory at 7T. This method showed excellent intra-session reproducibility...
https://onlinelibrary.wiley.com/doi/full/10.1002/hbm.70176#
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AMAZING opportunity, don't miss it!
add a skeleton here at some point
9 months ago
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reposted by
Noam Shemesh
Tim Witney
9 months ago
It’s the honour of a lifetime to be elected as ESMI's President-elect. Thank you for your faith in me. I will work hard to promote the values of the Society to a broad audience and be a strong advocate for the discoveries you have made in molecular imaging. 🙏🏻
www.kcl.ac.uk/news/profess...
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Professor Tim Witney elected Vice President of ESMI
Professor Tim Witney, Wellcome Trust Senior Research Fellow and Professor of Molecular Imaging at the School of Biomedical Engineering & Imaging Sciences, has been elected the Vice President of the Eu...
https://www.kcl.ac.uk/news/professor-tim-witney-elected-vice-president-of-esmi
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check out our new preprint! Together with Joana Carvalho and Koen Hak (and co-authors) we developed an ultrafast fMRI with layer resolution, and show how feedback/feedforward signals can be mapped from a layer connective field model
www.biorxiv.org/content/10.1...
MORE in a few weeks!
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Layer connective fields from ultrafast resting-state fMRI differentiate feedforward from feedback signaling
Deciphering the directionality of information flow in cortical circuits is essential for understanding brain dynamics, learning, and neuroplasticity after injury. However, current non-invasive methods...
https://www.biorxiv.org/content/10.1101/2025.02.23.639720v1.abstract
10 months ago
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reposted by
Noam Shemesh
Alessandro Gozzi
10 months ago
🔍 New must-see resource! 🧠 --> Reproducible Brain Charts – an open-data tool for mapping brain development & mental health
www.biorxiv.org/content/10.1...
👏 Kudos to
@ted-satterthwaite.bsky.social
and Michael Milham
@childmindinstitute.bsky.social
for leading this effort!
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reposted by
Noam Shemesh
Uzay Emir
10 months ago
Consistent with earlier publications, the
#PETALUTE
sequence features enhanced incoherent sampling for compressed sensing (CS). Through simulation, phantom, and in vivo comparisons, results demonstrate PETALUTE's competitive performance against conventional nuclei
#MRSI
and
#MRI
methods.
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Feasibility and comparison of 3D modified rosette ultra-short echo time (PETALUTE) with conventional weighted acquisition in 31P-MRSI - Scientific Reports
Scientific Reports - Feasibility and comparison of 3D modified rosette ultra-short echo time (PETALUTE) with conventional weighted acquisition in 31P-MRSI
https://www.nature.com/articles/s41598-025-90630-y
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reposted by
Noam Shemesh
Ileana Jelescu
10 months ago
Our first experimental demonstration of changes in diffusivity and kurtosis in the rat somatosensory pathway, where BOLD responses are not detected. Congratulations, Andreea Hertanu!
@snsf-ch.bsky.social
@fbm-unil.bsky.social
add a skeleton here at some point
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20
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reposted by
Noam Shemesh
Imaging Neuroscience
10 months ago
New paper in Imaging Neuroscience by Akul Sharma, Dominique Duncan, et al: Bundle-specific tractography approach for identifying white matter microstructural changes following traumatic brain injury in rats: An EpiBioS4Rx study
doi.org/10.1162/imag...
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reposted by
Noam Shemesh
Imaging Neuroscience
10 months ago
New paper in Imaging Neuroscience by Andreea Hertanu, Tommaso Pavan, and Ileana O. Jelescu: Somatosensory-evoked response induces extensive diffusivity and kurtosis changes associated with neural activity in rodents
doi.org/10.1162/imag...
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reposted by
Noam Shemesh
Imaging Neuroscience
10 months ago
New paper in Imaging Neuroscience by Jayvik Joshi, Manisha Aggarwal, et al: Distinguishing microgliosis and tau deposition in the mouse brain using paramagnetic and diamagnetic susceptibility source separation
doi.org/10.1162/imag...
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reposted by
Noam Shemesh
Tim Witney
10 months ago
Dear wonderful imaging community, I'm running for (vice)president of the European Society for Molecular Imaging - ESMI. A society I care deeply about. The election opens on 18th February for all members of the society. I would be very grateful for your vote. 🙏 Tim
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reposted by
Noam Shemesh
Alessandro Gozzi
11 months ago
fMRI data acquisition and analysis for task-free, anesthetized rats
www.nature.com/articles/s41...
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fMRI data acquisition and analysis for task-free, anesthetized rats - Nature Protocols
We present an fMRI acquisition protocol for anesthetized rats, suitable for various scanners and field strengths, which includes animal handling, MRI sequence parameters, data conversion, preprocessin...
https://www.nature.com/articles/s41596-024-01110-y
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See our latest paper in Investigative Radiology, incorporating DTI and T2* Microscopy to detect precursor lesions of pancreatic cancer!
journals.lww.com/investigativ...
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Pancreatic Intraepithelial Neoplasia Revealed by... : Investigative Radiology
d detect PanIN. Materials and Methods DTI was explored for the detection and characterization of PanIN in genetically engineered mice (KC, KPC). Following in vivo DTI, ex vivo ultrahigh-field (16.4...
https://journals.lww.com/investigativeradiology/fulltext/9900/pancreatic_intraepithelial_neoplasia_revealed_by.278.aspx
11 months ago
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