The humanitarian crisis in Gaza has gone from horrible to hell on earth. Over 60K people have been killed, mostly women & children. The Netanyahu government must allow the UN-led aid distribution system to resume. Children are starving, and we are on the brink of a full-blown famine:

Here's our new preprint led by @wdhale.bsky.social with @rhuganir.bsky.social: "Architecture, Activation, and Conformational Plasticity in the GluA4 AMPA Receptor" www.biorxiv.org/content/10.1... #iGluRs #cryoEM Some key points below that Dylan discovered:

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

Letter from Dem Senator Chris Van Hollen (MD) requesting a meeting with Salvadoran President Nayib Bukele To discuss MD father Kilmar Abrego Garcia's return "If Kilmar is not home by midweek – I plan to travel to El Salvador this week to check on his condition and discuss his release."

As someone who grew up in NJ, and an American, I am so proud of @corybooker.com for making a stand. I would love to see my current representation in the Senate @vanhollen.senate.gov @alsobrooks.senate.gov do the same.

Elon Musk proves once and for all that money really can’t buy happiness.

I may be tired and a little hoarse, but as I said again and again on the Senate floor, this is a moment where we cannot afford to be silent, when we must speak up.

Here's our newest study: we reveal the molecular principles of neuronal excitation by glutamate, and how physiological temperatures influence this process. www.nature.com/articles/s41... www.nature.com/articles/d41... Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com

US citizens should review this as well. www.aclu.org/know-your-ri....

Stand Up for Science made the news. youtu.be/QYLFGelUOj0?...

Stand up for Science DC! #SUFS

The MARC train from Baltimore to DC this morning is SOLD OUT for Stand up for Science!

Do any of my Canadian colleagues have recommendations for the best Canadian whiskies?

If you’re dismayed by what’s going on right now, focus on 2026 and don’t lose focus. Identify who your representatives are and be prepared to hold them to account. Without significant change in 2026 all of the marches, phone calls and social media posts are moot.

The catastrophic impact of all of these cuts with so little ‘savings’ indicates that the so-called bloat in the government is vastly exaggerated. We’re losing tremendous resources by cutting a fraction of what Elon Musk received in government handouts.

Congratulations Ed!

Great meeting at #BPS2025! #iglur

Happy International Day of Women and Girls in Science! 🧪 www.unesco.org/en/articles/...

I am strongly against the ‘budget cuts’ and other ‘policy’ decisions that are being made - several seem to be illegal. But having watched this circus since 2015, I’m convinced that the responsible parties aren’t graded on their performance as much as the volume of outrage generated.

So if the 15% indirect cost cap stands. Does this mean that researchers will have to pay the reminder of operating expenses directly from the award? Or are there NIH policies or laws that forbid this?

Google AI summaries have introduced me to some great literature I’ve never seen before. But that’s mostly because it’s unrelated to what I’m searching.

Well this doesn’t happen every day

The Channels, Receptors & Transporters Subgroup of the @biophysicalsoc.bsky.social is excited to announce the final program for our 2025 Symposium. Please join us on Feb 15 to hear from @willowcoyote.bsky.social @drcontrexin.bsky.social @corrylab.bsky.social and others 👇Thanks to our sponsors!

I made a feed for glutamate receptor ion channels. It picks up anything with the tag #iGluRs and also AMPA and NMDA receptors. (Sorry KAR and delta fans, only three terms, forgive me) You can pin the feed and/or like it. bsky.app/profile/did:...

Baltimore waterfront this morning

I am happy to announce that Dan Pederick will join the Department of Neuroscience at Johns Hopkins as an Assistant Professor this summer. Dan joins us from Liqun Luo’s laboratory at Stanford University, where he was studying how cell surface molecules regulate neural circuit assembly.

Happy to say our paper on SynGAP1 "SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity," is out today in Science. The results of this paper surprised me and will have a significant impact on therapeutics for SRID. Repost from X. www.science.org/doi/10.1126/...

Tom Reese has passed. He was a truly pioneering explorer of neuronal ultrastructure, and really nice guy to talk to. I am grateful to have known him. www.mbl.edu/news/obituar...

Here is a starter pack for CryoEM/ET enthousiasts To be completed go.bsky.app/JmQksC

Welcome to BlueSky @paulschanda.bsky.social and everyone else that recently have joined this friendly place ❤️ If you're looking for biophysics and structural biology friends, have a look at these two "starter packs" bsky.app/starter-pack... & bsky.app/starter-pack...