"δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice" www.ibroneuroscience.org/article/S030...

The winner of OneNeuro's January #FotoFriday #FluorescenceFriday contest is "Electrophysiology of Cultured Neurons" submitted by Madison Yorkowski in the Ali Fatemi Lab at Kennedy Krieger Institute. View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/

New Neuroscience Masters Degree at Johns Hopkins The M.S. degree in Neuroscience is a full-time in-person program consisting of intensive coursework followed by 12 months of laboratory research. The application deadline is May 15, and more information is available at neuroscience.jhu.edu/graduate/51

"Choose your training environment carefully. Lab culture and institutional culture will significantly impact your happiness and success, so choose carefully." - OneNeuro Profile: Seth Blackshaw, PhD @sethblackshaw.bsky.social www.oneneurojhu.org/2026/01/29/o...

Johns Hopkins scientists discover that brain cells constantly attempt to produce myelin at a steady pace throughout the brain, offering new insights for treating multiple sclerosis. @jhu.edu www.oneneurojhu.org/...

"We study human vision, focusing on the neural and computational basis of high-level vision using cognitive and computational neuroscience techniques." — Mick Bonner , PhD @mickbonner.bsky.social www.oneneurojhu.org/2026/01/21/o...

Study section done. Now can enjoy the PC learning and memory meeting! Looking forward to some stimulating science chats on the ski lift as well this weekend.

Rescue of excitotoxicity in a mouse model of a rare neurodevelopmental disorder by ASO treatment.

We just posted our new paper, “Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant”. In this paper, we, in collaboration with Shu-Ling Chiu's lab, generated a mouse model of a rare missense mutation in the AMPA receptor GluA1 subunit. www.biorxiv.org/content/10.6...

The winner of OneNeuro's November #FotoFriday #FluorescenceFriday contest is "Portrait of a Claustrocortical Neuron" submitted by Baldomero B. Ramírez Cantú in the Solange Brown Lab at @hopkinsmedicine.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/

The winner of OneNeuro's October #FotoFriday #FluorescenceFriday contest is "Purkinje cell complex spikes & simple spikes," submitted by Chenhao Bao in the Cullen lab at JHU Biomedical Engineering. @thecullenlab.bsky.social @chenhaobao.bsky.social Complete gallery: www.oneneurojhu.org/art/

Johns Hopkins scientists discover how brain cells form nanotube networks to transport toxic molecules like amyloid-beta between neurons, offering new insights into Alzheimer's disease progression. @hyungbaekwon.bsky.social @hopkinsmedicine.bsky.social @science.org www.oneneurojhu.org/2025/11/06/n...

Four @jhu.edu @jhuartssciences.bsky.social faculty members were recently named part of three large-scale, multi-institutional, highly competitive collaborations funded by the @simonsfoundation.org to explore novel areas in established fields. www.oneneurojhu.org/2025/09/23/f...

New test detects brain cancers in cerebrospinal fluid with 80% sensitivity and 100% specificity, enabling clinicians to better detect cancer and better understand the disease status, supporting a more tailored approach to patient care. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/06/t...

The winner of OneNeuro's September #FotoFriday #FluorescenceFriday contest is "The Cochlear Constellation," submitted by Yassine Balhi in Amanda Lauer's lab at @hopkinsmedicine.bsky.social. View the complete gallery here: www.oneneurojhu.org/art/

Novel in utero gene therapy shows promise for spinal muscular atrophy, with potential to help babies reach motor milestones previously thought impossible. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/15/n...

I am excited to announce that the Johns Hopkins University Solomon H. Snyder Department has become an interdivisional department between the School of Medicine and the Krieger School of Arts and Sciences, unifying neuroscience research and education across the university. hub.jhu.edu/2025/09/15/j...

OneNeuro's August #FotoFriday #FluorescenceFriday contest winner is "Cellular Subtype Composition of an Amphetamine-activated Ensemble in mPFC," by Suhaas Adiraju from @martinowk.bsky.social at the @lieberinstitute.bsky.social View the complete gallery here: www.oneneurojhu.org/art/

The statement by Caroline Kennedy about RFK Jr has aged well www.youtube.com/shorts/fm0-a...

My hero!!!!

Johns Hopkins scientists discover how a protein organizes message-carrying "bubbles" in brain synapses—advancing understanding of memory formation and learning. www.oneneurojhu.org/... @watanabelab.bsky.social

A giant in the field! Gave some of the best talks I have ever seen.

A legend. Was and am still inspired by his work. Sad to hear this.

Go Tricia! Go Hopkins!

We are thrilled to announce that OneNeuro Co-Director Patricia Janak, Ph.D., has been elected as the 2026-2027 President of the Society for Neuroscience (SfN). @janaklab.bsky.social View the official announcement: www.sfn.org/publications...

Well said, Rick. I remember covering your groundbreaking work on SYNGAP many years ago for Monitor on Psychology magazine. I fully hope your research endures.

🚨 BREAKTHROUGH: UMSOM researchers win $250K NIH prize for tech that delivers CRISPR across the blood-brain barrier. 🧠🧬 Led by Dr. Poulopoulos, the Crisaptics Trans-BBB Team’s work could transform treatment for Huntington’s & glioblastoma. 🔗 bit.ly/44NGUDP #CRISPR #NIH #Neuroscience #MedEd #MedSky

Dynamic extracellular interactions with AMPA receptors https://www.biorxiv.org/content/10.1101/2025.07.11.664166v1

The winner of OneNeuro's June #FotoFriday #FluorescenceFriday contest was submitted by Victor Omoniyi at the Marie Hardwick and Lauren Jantzie Laboratories. @johnshopkinsmmi.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/...

"Labs like mine, working toward treatments that could transform thousands of lives, are forced to shut down projects, turn away talent, and walk away from cures within reach. It's not abstract. It's not academic. This is real. This is happening now. And it is crushing." tinyurl.com/3vt7wc99

In this essay in Hopkins Magazine, I talk about how NIH budget cuts will delay or stop the translation of basic science to the clinic and impact kids with intellectual disability, autism, and epilepsy. hub.jhu.edu/magazine/202...

New gene therapy approach targets rare genetic diseases by boosting expression of autism-linked genes. "We stand on the brink of medical breakthroughs—we are so close." @jmcoller.bsky.social www.oneneurojhu.org/2025/06/26/a...

OneNeuro Discovery Awards 2025 announced. Three projects spanning School of Medicine, Krieger School of Arts & Sciences, and Bloomberg School of Public Health: axon research, psilocybin for amblyopia, and mosquito neuroscience View the official announcement here: hub.jhu.edu/2025/06/17/j...

BREAKING: A federal judge reversed National Institutes of Health's terminations of hundreds of critical research grants that were canceled because of their alleged connection to disfavored topics, including diversity, equity, inclusion, and gender identity. This is a major win for public health.

Here's our new preprint led by @wdhale.bsky.social with @rhuganir.bsky.social: "Architecture, Activation, and Conformational Plasticity in the GluA4 AMPA Receptor" www.biorxiv.org/content/10.1... #iGluRs #cryoEM Some key points below that Dylan discovered:

Warning about national brain drain and the end of American Science as we know it. www.nytimes.com/2025/06/03/u...

"It's a horror show. We're under attack in every way all the time," says Sarah Kobrin, who has worked at the National Cancer Institute for more than 21 years. "We're told we're worthless. We're told we're cheats.… They're breaking things that won't be repairable." www.npr.org/sections/sho...

“Bhattacharya later testified before Congress that it – and he – immediately became targets of suppression and censorship by those leading scientific agencies.” This line in CNN’s piece on the Bethesda Declaration is really inexcusable. Bhattacharya was never censored. He took case to SCOTUS & lost

The NIH has not issued a single new call for proposals since the end of January.

I wanted to show support for these brave public servants and to allow others, including the scientific community, to join me. In partnership with @standupforscience.bsky.social‬, we have a way for you to do that... www.standupforscience.net/bethesda-dec...

As the United States cuts budgets and restricts immigration, China and Europe are offering researchers money and stability. Article Link: www.nytimes.com/2025/06/03/u...

The winner of OneNeuro's May #FotoFriday #FluorescenceFriday contest, "Astrocytes chewing tau aggregates in mouse brain", was submitted by Meghraj Baghel at the Philip C. Wong Lab. View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/

My interview with a science communication journal in Germany is live, we discussed: why academics with tenure (power and influence) need to step up, how science can become resilient, opportunities to shift the narrative, and why scientists abroad should pay attention. @sciforgood.bsky.social

US Beacon for Science May Be Dimming www.nytimes.com/2025/06/03/u... #MarciaMcNutt: “We are embarking on a major experiment in restructuring the innovative engine in America &China is the control." @ardemp.bskyverified.social @rhuganir.bsky.social @mathias-unberath.bsky.social @insitro.bsky.social

Another breakthrough made possible by federal funding The result “is a triumph for the American peoples’ investment in biomedical research” Baby Is Healed With World’s First Personalized Gene-Editing Treatment www.nytimes.com/2025/05/15/h...

"We've been able to make significant progress with funding from the National Institutes of Health, but the federal government's cuts put everything at risk and cast a dark cloud over our lab—and over the entire SynGap1 community," says @rhuganir.bsky.social Article Link: tinyurl.com/ytmufk9j

Here is an article about how NIH cuts are impacting research on rare genetic disorders like autism. hub.jhu.edu/2025/05/14/r...

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

"'The consequences are enormous,' said Drew Weissman, director of the Institute for RNA Innovation at the University of Pennsylvania and a 2023 Nobel laureate in medicine for the discoveries that enabled the mRNA Covid vaccines. 'It has so much potential for other therapies.'"

important historical perspective on the value of federal funding of basic research at universities: "These are the building blocks of America's extraordinary strength, created over the last 100 years, and they are now being dismantled in 100 days" 🧪 www.youtube.com/watch?v=0Qk4...