Federico Lopez
@flopezos.bsky.social
📤 786
📥 1108
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Evolutionary biology, genomics, bioinformatics, social insects.
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Federico Lopez
Richard Van Noorden
3 days ago
Tens of thousands of papers published in 2025 contain fake/hallucinated citations, an analysis by Nature and Grounded AI suggests By
@miryamnaddaf.bsky.social
and Beth Quill |
@nature.com
www.nature.com/articles/d41...
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Hallucinated citations are polluting the scientific literature. What can be done?
Tens of thousands of publications from 2025 might include invalid references generated by AI, a Nature analysis suggests.
https://www.nature.com/articles/d41586-026-00969-z
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Federico Lopez
Johns Hopkins Berman Institute of Bioethics
10 days ago
Major conference catches illicit AI use — and rejects hundreds of papers. The papers’ watermarks allowed organizers to detect use of large language models in peer review.
www.nature.com/articles/d41...
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Major conference catches illicit AI use — and rejects hundreds of papers
The papers’ watermarks allowed organizers to detect use of large language models in peer review.
https://www.nature.com/articles/d41586-026-00893-2
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Federico Lopez
Heng Li
5 days ago
LongcallR for competitive SNP calling and haplotype phasing, and simplified allele-specific analysis with long RNA-seq reads. Found ~100 junctions affected by SNPs per sample with most junctions novel. Developed by Neng Huang. Published in
@natmethods.nature.com
. Read at
rdcu.be/faKhL
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SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads
Nature Methods - In this study, long-read RNA sequencing achieves accurate single-nucleotide polymorphism calling, haplotype phasing and allele-specific expression analysis.
https://rdcu.be/faKhL
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Hajk-Georg Drost
11 days ago
How much protein diversity can Life on Earth actually generate? With DIAMOND DeepClust, we show how billions of proteins across the tree of life can be clustered at low-identity for downstream analytics tasks. 📚Paper:
www.nature.com/articles/s41...
💻Code:
github.com/bbuchfink/di...
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Nicola Rennie
8 days ago
🎉 ggauto is now on CRAN 🎉 An
#RStats
package that selects better chart types, and provides more accessible styling for
#ggplot2
plots 📊 Blog post explaining why I made it and how it works:
nrennie.rbind.io/blog/introdu...
#DataViz
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Introducing ggauto: automating better charts – Nicola Rennie
The ggauto package is an opinionated ggplot2 extension package that aims to help people make better charts by default. This blog post explains why it exists and how it works.
https://nrennie.rbind.io/blog/introducing-ggauto/
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Federico Lopez
Gergely Orosz
8 days ago
If you use GitHub (especially if you pay for it!!) consider doing this *immediately* Settings -> Privacy -> Disallow GitHub to train their models on your code. GitHub opted *everyone* into training. No matter if you pay for the service (like I do). WTH
github.com/settings/cop...
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IEEE Spectrum
11 days ago
Entomologists and particle accelerator physicists have collaborated to produce a new 3D atlas of what makes up an ant, including muscles, nerves, digestive tracts, and exoskeletons. The images are free to access.
spectrum.ieee.org/3d-scanning-...
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Emmanuelle Chaze
11 days ago
🔴 The historic city center of Lviv, a UNESCO World Heritage site, is under attack by russian drones. Mayor Andryi Sadovy shared this picture, other channels show several fires across the city. In daytime, Russia unleashed dozens of drones over Ukraine.
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Olena Halushka
11 days ago
The russians have just violently bombed Lviv city center, there's fire in at least two residential apartments, one of them is right next to the St.Andriy's church. Two people are severely injured. The city is still under attack.
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Michael Hiller
23 days ago
I wrote a short Nature Methods News & Views piece on deep learning based gene finders such as ANNEVO.
www.nature.com/articles/s41...
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Learning genes deeply - Nature Methods
Annevo uses deep learning to achieve unprecedented accuracy in eukaryotic gene annotation, approaching the performance of evidence-based methods.
https://www.nature.com/articles/s41592-026-03035-8
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Federico Lopez
Nature Methods
19 days ago
ANNEVO uses a deep learning approach to advance accurate and scalable ab initio gene annotation of evolutionarily diverse genomes.
www.nature.com/articles/s41...
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Highly accurate ab initio gene annotation with ANNEVO - Nature Methods
ANNEVO advances accurate and scalable ab initio gene annotation of evolutionarily diverse genomes using deep learning approach modeling sequence evolution and long-range dependencies and mixture of ex...
https://www.nature.com/articles/s41592-026-03036-7
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Federico Lopez
Nature Biotechnology
16 days ago
A decade of research in review For Nature Biotechnology’s 30th anniversary, our editors look back at a few of their favorite papers published in the past decade
go.nature.com/4sWhZs1
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Federico Lopez
Daniel Kronauer
15 days ago
Ants are experts at telling nestmates from foreigners via subtle differences in odor profiles. In this new paper, we explore the conditions under which ants develop and maintain tolerance to foreigners. Turns out the ant recognition system is surprisingly plastic.
www.cell.com/current-biol...
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Tolerance toward foreigners in ants requires chronic exposure for establishment but only sporadic exposure for maintenance
Bailly et al. show that ants learn to tolerate genetically distinct non-nestmates through prolonged exposure. Once established, this tolerance persists with occasional re-encounters with ants of the s...
https://www.cell.com/current-biology/fulltext/S0960-9822(26)00228-9
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James Ferguson
24 days ago
kuva v0.1.4 released - 4 new plots (Polar, Ternary, Ridgeline, Density) - A completely reworked legend system - SVG rendering 50-70% faster, and Manhattan plots 22× faster at 1M SNPs - Many bug fixes and extra features
github.com/Psy-Fer/kuva
crates.io/crates/kuva
#rust
#bioinformatics
#dataviz
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Federico Lopez
David Ho
24 days ago
The 2026 National Science Foundation budget is $8.75 Billion.
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First 6 Days of Iran War Cost U.S. $11.3 Billion, Pentagon Says
https://www.nytimes.com/live/2026/03/11/world/iran-war-news-trump-oil-israel?unlocked_article_code=1.SlA.vTQm.rWeA0T_H9N7Y&smid=url-share
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Jason Dinh
24 days ago
NEW: for
@nytimes.com
, I wrote about a new study showing that queen bumblebees can breathe underwater, surviving submerged for a week the “remarkable” study stems from a lab snafu, when a co-author thought she accidentally drowned several bees—but later found that they were alive 🧪 gift link 🎁
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Bumblebee Queens Can Breathe Underwater
https://www.nytimes.com/2026/03/10/science/bumlebees-queens-underwater-breathe.html?unlocked_article_code=1.SFA.sVfe.ZuCKYwk-0Fie&smid=url-share
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Federico Lopez
Nature Portfolio
about 1 month ago
Butterflies and moths are key indicators of functioning and healthy ecosystems. A Review in Nature Reviews Biodiversity describes the evolutionary history of the order Lepidoptera and tracks shifts in researchers’ understanding of the clade in the genomic era.
go.nature.com/4r0kbgS
🌍 🧪
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Federico Lopez
Nature Ecology & Evolution
about 1 month ago
New Review 👇 The molecular evolution of vertebrate organs:
www.nature.com/articles/s41...
Margarida Cardoso-Moreira discusses rates of evolution of organs and cell types, molecular mechanisms of organ evolution and how complex traits contributed to the diversification of vertebrates.
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The molecular evolution of vertebrate organs - Nature Ecology & Evolution
This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms of organ evolution and how complex tr...
https://www.nature.com/articles/s41559-026-03003-7
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Federico Lopez
Daniel Kronauer
about 1 month ago
Thanks to micro-CT and
www.antscan.info
, you can now explore high resolution, 3D ant images from anywhere in the world. Fantastic work from Julian Katzke, Francisco Hita Garcia,
@economo.bsky.social
, Thomas van de Kamp and colleagues just dropped:
www.nature.com/articles/s41...
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Antscan
https://www.antscan.info
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Federico Lopez
Eric Topol
about 1 month ago
On sabotage of our young scientists, by
@holdenthorp.bsky.social
@science.org
www.science.org/doi/10.1126/...
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📄 A sterility-associated long noncoding RNA involved in honey bee caste determination and adult queen and worker fertility 🐝 ⬇️
www.pnas.org/doi/abs/10.1...
about 1 month ago
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Federico Lopez
Nature Ecology & Evolution
about 1 month ago
Phylogenetic and functional analyses across 34 Lepidoptera and 183 plant species show that hexenal isomerases found in Lepidoptera exhibit functional convergence with those found in plants despite having evolved independently from unrelated enzyme families 🧪
www.nature.com/articles/s41...
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Convergent evolution of hexenal isomerases in Lepidoptera and plants - Nature Ecology & Evolution
Phylogenetic and functional analyses across 34 Lepidoptera and 183 plant species show that hexenal isomerases found in Lepidoptera exhibit functional convergence with those found in plants despite hav...
https://www.nature.com/articles/s41559-026-02999-2
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Federico Lopez
Jeffrey Ross-Ibarra
about 1 month ago
Recently we're working with SNPs from whole genome assemblies to estimate ARGs. It's a pain to go from alignment files to vcf, keeping track of masked and invariant sites. So we wrote a snakemake/SLURM pipeline. Hope it's useful to others, and don't hesitate to post issues if there are problems!
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GitHub - RILAB/argprep: Snakemake pipeline for generating SINGER input files from whole genome alignment .maf files.
Snakemake pipeline for generating SINGER input files from whole genome alignment .maf files. - RILAB/argprep
https://github.com/RILAB/argprep
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Federico Lopez
Lars Chittka
about 1 month ago
A new documentary "Secrets of The Bees" will air on National Geographic on 31 March and land on Disney+ on 1 April and our bees are in it! See here for the trailer:
www.youtube.com/watch?v=Mej2...
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Secrets of the Bees | Official Trailer | Narrated by Bertie Gregory | National Geographic
YouTube video by National Geographic
https://www.youtube.com/watch?v=Mej2usrRCl0
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📄 Repeated evolution of supergenes on an ancient social chromosome 🐜🧬 ⬇️
www.cell.com/current-biol...
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Repeated evolution of supergenes on an ancient social chromosome
Lajmi et al. describe a novel supergene associated with social structure in desert ants. Surprisingly, this supergene evolved on an ancient chromosome that also evolved an analogous supergene in fire ...
https://www.cell.com/current-biology/fulltext/S0960-9822(26)00139-9
about 1 month ago
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Federico Lopez
Richard McElreath 🐈⬛
about 1 month ago
If we are making lists of non-ignorable "complexity" in biology, how about the interaction of selection and development? Many biologists find it boring (unnecessary complexity) or threatening (old naive adaptationism called into question).
@mauriciogforero.bsky.social
does good work in this area!
add a skeleton here at some point
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📄 A parasitic, parthenogenetic ant with only queens and without workers or males 🐜 ⬇️
www.cell.com/current-biol...
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A parasitic, parthenogenetic ant with only queens and without workers or males
Hamaguchi, Kinomura and colleagues describe an ant species that lacks workers and males and consists exclusively of queens.
https://www.cell.com/current-biology/fulltext/S0960-9822(25)01621-5
about 1 month ago
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Federico Lopez
UNITED24 Media
about 1 month ago
🔴 Over 212,000 Russian war crimes documented in Ukraine since 2022.
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Federico Lopez
Phillips OBrien
about 1 month ago
It is four years ago today that the Russians launched their full scale invasion of Ukraine. Many in the west wrote Ukraine off and prophesied a “shock and awe” Russian victory. Instead Ukraine defied its attacker and their fight for freedom became decisive for the future of European freedom.
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Anne Applebaum
about 1 month ago
Four years have passed since Russia's full scale invasion of Ukraine. Russia was supposed to win in three days. Instead, Ukraine reinvented modern warfare, built a drone industry, and can destroy a thousand Russian soldiers in a day. Ukraine can win.
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📄 Topological approaches in animal comparative genomics 🧬 ⬇️
www.annualreviews.org/content/jour...
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Topological Approaches in Animal Comparative Genomics
The surge in chromosome-scale genome sequences from across the tree of life, as well as new comparative methods, has made it possible to study the impact of genomic changes on macroevolution. In this ...
https://www.annualreviews.org/content/journals/10.1146/annurev-animal-030424-084541?TRACK=RSS
about 1 month ago
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Federico Lopez
Nature Reviews Genetics
about 2 months ago
New online! Annotating genomes at increased scale and resolution
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Annotating genomes at increased scale and resolution
Nature Reviews Genetics, Published online: 17 February 2026; doi:10.1038/s41576-026-00937-3In this Review, Ji et al. overview how rapidly advancing experimental and computational methods are enabling improved and automated annotation of gene structure and function, providing researchers with genome annotation resources of unprecedented scale and resolution.
http://dlvr.it/TR1MJm
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📄 Increasing applied pesticide toxicity trends counteract the global reduction target to safeguard biodiversity 🐝🧪 ⬇️
www.science.org/doi/10.1126/...
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Increasing applied pesticide toxicity trends counteract the global reduction target to safeguard biodiversity
The 15th United Nations Biodiversity Conference (COP15) obligates all countries to reduce pesticide risks by 50% by 2030. In this study, we derived the trends of total applied toxicity (TAT) globally ...
https://www.science.org/doi/10.1126/science.aea8602?utm_campaign=Science&utm_medium=ownedSocial&utm_source=facebook
about 2 months ago
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Federico Lopez
American Museum of Natural History
about 2 months ago
Here’s one lobster that you might not want with a side of butter: the lobster moth! Named for its lobster-like larval form, this wide-ranging insect inhabits parts of Europe & Asia. While it resembles a crustacean, it can also mimic ants as a way to deter potential predators.
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Nature Protocols
2 months ago
New Article! Tutorial: annotation of animal genomes
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Tutorial: annotation of animal genomes
Nature Protocols, Published online: 28 January 2026; doi:10.1038/s41596-025-01301-1This Tutorial integrates state-of-the-art tools into a streamlined workflow to create high-quality annotations for animal genomes, assigning gene symbols and annotating repeat regions for both protein-coding and non-coding RNA genes, before assessing annotation quality.
http://dlvr.it/TQcHsP
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Federico Lopez
Nature Reviews Genetics
about 2 months ago
New online! Evolutionary causes and consequences of gene duplication
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Evolutionary causes and consequences of gene duplication
Nature Reviews Genetics, Published online: 16 February 2026; doi:10.1038/s41576-026-00935-5Gene duplication is a key evolutionary mechanism, as initially redundant paralogues diverge over time. The authors review how adaptive and non-adaptive forces influence the evolutionary fates of gene duplicates, highlighting the importance of function–fitness relationships and gene expression dynamics.
http://dlvr.it/TQzp1d
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📄 No evidence that haplodiploidy favors the evolution of eusociality 🐝🐜 ⬇️
www.pnas.org/doi/abs/10.1...
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No evidence that haplodiploidy favors the evolution of eusociality | PNAS
The potential role of haplodiploid sex determination in promoting the evolution of altruism and eusociality has been the subject of intense debate ...
https://www.pnas.org/doi/abs/10.1073/pnas.2517458123
about 2 months ago
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Federico Lopez
Obsidian
about 2 months ago
Anything you can do in Obsidian you can do from the command line. Obsidian CLI is now available in 1.12 (early access).
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Nature Reviews Genetics
2 months ago
New online! The genetic foundations of convergent traits
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The genetic foundations of convergent traits
Nature Reviews Genetics, Published online: 02 February 2026; doi:10.1038/s41576-026-00933-7Convergent phenotypic evolution, the independent acquisition of similar or nearly identical traits in multiple species, is widespread. Allard and Kumar explore the spectrum of molecular convergence in multicellular organisms, evaluate computational and artificial intelligence-based methods for detecting adaptive genetic convergence, and highlight how comparative genomics of convergent phenotypes informs complex trait evolution and human health.
http://dlvr.it/TQjVkn
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Federico Lopez
Nature Reviews Genetics
about 2 months ago
ICYMI: New online! Emergence and evolution of protein-coding de novo genes
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Emergence and evolution of protein-coding de novo genes
Nature Reviews Genetics, Published online: 28 January 2026; doi:10.1038/s41576-025-00929-9De novo gene evolution entails the birth of new genes from previously non-coding DNA. In this Review, Bornberg-Bauer and Eicholt overview how protein-coding de novo genes are identified, the mechanistic and evolutionary processes underlying their emergence and evolution, and the patterns in their encoded protein structures.
http://dlvr.it/TQmD82
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Federico Lopez
Nature Portfolio
about 2 months ago
For almost two decades, scientists have debated whether sponges or comb jellies are the first animal lineage. A feature in Nature describes how some researchers are calling for a more harmonious approach.
#evosky
🧪
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What were the first animals? The fierce sponge–jelly battle that just won’t end
For almost two decades, scientists have debated whether sponges or comb jellies are the first animal lineage. Now some are calling for a more harmonious approach.
https://go.nature.com/45AbGRO
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Disgusting.
add a skeleton here at some point
about 2 months ago
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Federico Lopez
Carl Zimmer
2 months ago
I wrote today about AlphaGenome, Google DeepMind's AI for DNA. It's powerful, experts told me, but it won't solve the mysteries of the genome overnight. Gift link:
nyti.ms/4k5NFIl
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https://nyti.ms/4k5NFIl
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Federico Lopez
Nature Portfolio
2 months ago
A paper in Nature presents AlphaGenome, a deep learning model that can predict the function of long DNA sequences, up to one million base pairs. The tool can predict how DNA sequence variations affect different biological processes.
go.nature.com/4t5JQa7
🧬 🧪
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Federico Lopez
Rob Waterhouse
2 months ago
A phylogeny of 4'854
#insects
--- with structural
#genomics
shedding light on protein functions & remote homologs
www.nature.com/articles/s41...
#biodiversity
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Structural genomics sheds light on protein functions and remote homologs across the insect tree of life - Cell Research
Cell Research - Structural genomics sheds light on protein functions and remote homologs across the insect tree of life
https://www.nature.com/articles/s41422-026-01220-0
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Federico Lopez
Mark A. Hanson
3 months ago
We've got ISSUES. Literally. We scraped >100k special issues & over 1 million articles to bring you a PISS-poor paper. We quantify just how many excess papers are published by guest editors abusing special issues to boost their CVs. How bad is it & what can we do?
arxiv.org/abs/2601.07563
A 🧵 1/n
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Federico Lopez
Kate from Kharkiv
2 months ago
This is Kupiansk today. Once a thriving town of 25,000 in Kharkiv region, now nothing but ruins and ash. Russia obliterated it. Murdered or drove out its people, and bombed it into dust.
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📄 A beginner's guide to structural variants in eco-evolutionary population genomics 🧬 ⬇️
onlinelibrary.wiley.com/doi/10.1111/...
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A Beginner's Guide to Structural Variants in Eco‐Evolutionary Population Genomics
Whole-genome sequencing (WGS) has greatly expanded researchers' ability to study structural variants (SVs), that is, the variation in the presence, number, orientation or position of a DNA sequence. ....
https://onlinelibrary.wiley.com/doi/10.1111/mec.70216
2 months ago
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Federico Lopez
American Museum of Natural History
2 months ago
Ever seen a pink grasshopper? A genetic mutation called erythrism (overproduction of red pigment) leaves some individuals looking pretty in pink! Though these rare insects are beautiful, their vivid coloring makes hiding from predators more difficult. Photo: Back from the Brink, CC BY-NC 2.0, flickr
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Olena Halushka
2 months ago
russia is preparing another massive combined attack to freeze us, Ukrainians to death. This is a large-scale crime against humanity, unfolding right now, live.
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