Happy to announce the release of TOGA2 data for 68 turtle genomes, generated with a cryptodiran and a pleurodiran turtle reference. The combined TOGA2 annotation consistently improves annotation completeness compared with RefSeq. All data at genome.senckenberg.de/download/TOGA2. Genome browsers ...

We now have genome browsers on our UCSC mirror at genome.senckenberg.de for the 1033 mammal and 866 bird assemblies, showing spliceAi, reference-based and ref-integrated TOGA2 tracks. Tables with links to all browsers are genome.senckenberg.de/TOGA2Mammali... & genome.senckenberg.de/TOGA2Aves.html

I wrote a short Nature Methods News & Views piece on deep learning based gene finders such as ANNEVO. www.nature.com/articles/s41...

I hear you want novelty🦎->🐢, chromosome evolution 🧬, sex determination🩷, link population history📈 & climate🌏🌡️? Or you share my love for wonderfully weird animals? Side-necked turtle genomes reveal chromosomal dynamics, skeletal innovation and cancer resistance www.biorxiv.org/content/10.6... A 🧵

Happy to share that our work with Ekaterina Osipova, @maggiemcko.bsky.social, Tim Sackton, Maude Baldwin & fantastic collaborators on convergent and lineage-specific genomic adaptations in sugar-feeding birds is published in Science www.science.org/doi/10.1126/.... While high sugar intake ...

Happy to present TOGA2, developed by Yury Malovichko @ymalovichko.bsky.social, the faster, memory-efficient & more accurate TOGA1 successor (github.com/hillerlab/TO...). And annotations, orthologs & gene loss/dup data generated with 4 references for 883 placental mammal and with 5 refs for 676 ...

🚀🧬🔥 Hot off the press — 2025! Don’t miss this must-read publication: bit.ly/4mJwFb7 This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨

phenomenal work from Terry's lab !! And unbelievable that funding for such exciting work is cut.

Back from the Biology of Aging Gordon Research Conference. Fantastic meeting. Great to meet old friends and making new ones.

Happy to share our review on "Linking phenotype to genotype using comprehensive genomic comparisons" in Current Op with @leonhilgers.bsky.social. Summary of recent work and a discussion of the challenges ahead. www.sciencedirect.com/science/arti...

You link #phenotype 🦜 to #genotype 🧬 with #comparative #genomics 💻? This #review is for you 📜: authors.elsevier.com/sd/article/S... We review new #methods, remaining #challenges and #future directions and highlight recent key studies. Thanks @hillermich.bsky.social! Please share! 🙂

And @pacbio.bsky.social updated the ultralow protocol based on our results. Checkout www.pacb.com/blog/new-amp...

Our work on long read sequencing of ethanol or difficult-to-sequence samples is out genomebiology.biomedcentral.com/articles/10..... Will help to sequence Earth's biodiversity @ebpgenome.bsky.social. w @bernhardbein.bsky.social & many great colleagues.

Checkout @xuelingyi.bsky.social manuscript on diet evolution in bats, with a focus on the super diverse Phyllostomid bat family. www.biorxiv.org/content/10.1...

To all #PSMC users. A prominent PSMC peak followed by a collapse is typically an artifact. @leonhilgers.bsky.social publiation in @currentbiology.bsky.social shows how to avoid this with simple parameter adjustments. www.cell.com/current-biol...

I am writing a short #review about linking #phenotype to #genotype 🧬using #comparative #genomics. There is a lot of amazing work and I would love to hear about your favorite studies 🥇 from the last 2-3 years! ✉️ Pls also send your own work here (or DM)🙂!! Please #repost!!! 🔁 (just joined bsky)

A news article for a lay summary also: www.nature.com/articles/d41...

Finally online - Bat genomes illuminate adaptations to viral tolerance and disease resistance www.nature.com/articles/s41... @hillermich.bsky.social @virology.bsky.social @emmateeling.bsky.social

Happy to report that our work on immune system adaptations in bats is now out in @nature.com 🦇🧬 www.nature.com/articles/s41... @ariadnamorales.bsky.social @batresearch.bsky.social @virology.bsky.social @DGKontopoulos.ecoevo.social.ap.brid.gy @sgn.one @bat1kgenomes.bsky.social Read more ...