And finally, Erika Hansson presenting the work from Irma Vitonyte on comparing endosymbiotic and free-living algae and the fitness trade-offs #EESSymbiosis www.biorxiv.org/content/10.6...

Next, Daniel Malumphy Montesdeoca on Paramecium and its two co-occurring symbionts Micractinium and Choricystis #EESSymbiosis

My kids asked me what I was like in the 90s and I told them to shut the fuck up and stop harvesting my data

Next, Fiona Savory on mapping Chlorella genotypes inside Paramecium using strain expressing different fluorescent proteins. Lots of advanced microscopy! Read more here www.biorxiv.org/content/10.6... #EESSymbiosis

Next, @benkinsjenkins.bsky.social on sea anemone endosymbiosis. Localization of Organelle Proteins by Isotope Tagging helped identify symbiosome-associated proteins, which were then studied using RNAi-based knock-outs. Do these proteins play a role in coral bleaching? #EESSymbiosis

Next, Erika Hansson on evol. pressures on endosymbiosis studied in Paramecium-Chlorella. Do fitness trade-offs between in- and out-of-symbiosis stabilize symbiosis? Growing Chlorella in nitrate rewires metabolism which works great outside of symbiosis but leads to symbiosis break-down #EESSymbiosis

So you are using IQ-TREE to estimate a tree for "deep time" phylogenetics using amino acid alignments. There is a lot of confusion about how to test model fit. Here are some suggestions.

Drinking this on St Guinness advertising day. untp.beer/b0rME Noa Pecan Mudcake Stout.

Who's ready for the #DunePartThree Trailer in just over 1 hour? 🍿

An excellent thread on why population doomerism is a gateway drug to genocide

why aren't other countries helping us with the strait of hormuz after we started an unjust war, cut off trade, and insulted them for a year?

"which means today, I probably wouldn’t recruit my younger self." What is wrong with people. I just have so much contempt for this shitty kind of attitude. Retire so someone better, deserving, and supportive of people, can have your funding, please.

This is kinda bonkers. In addition, 20 amino acids were found on Ryugu, along with uracil and vitamin B3. These have been found in other instances, but since the samples from Ryugu were collected directly from the asteroid and delivered in sealed capsules, contamination on Earth could be ruled out.

It is *fascinating* to me how quickly some people have gone completely from “we all must work in the office! human collaboration is vital and only happens in person!” to “I can replace all these pesky people with chatbots!” Definitely some commentary there about our society and who gets to choose.

We've gone from: "don't give people your passwords" to "give AI tech bros all of your photos" in not so many years. You'd have to be literally stupid to use this luxury surveillance, seven hells.

Oooh, how about one more? Down with AI, analog art rules artologica.etsy.com/listing/4472...

Having a hard time keeping up with the fast-moving field of origin of eukaryotes/Asgards archaea? Our new perspective article can help, we review the status of research over the last decade and where it's going. The archaeal roots of eukaryotic life www.pnas.org/doi/10.1073/...

I simply refuse to believe this isn’t a Chris Morris sketch:

Archaea hit prime time: www.bbc.co.uk/programmes/m...

And the UK government want to give all our NHS data to this creep's company. No thanks.

@ox.ac.uk - this is a huge problem. What are you doing to stop it?

I look at these kinds of protists ALL THE TIME. I have never seen them in situ like this. One cell. Absolutely remarkable. #protistsonsky

🚨 Wide ranging powers have been voted through to restrict Internet access 🚨 Ministers will be able to impose digital ID checks, curfews and VPN restrictions without Parliamentary scrutiny. This can be used on websites, social media, apps and games with no need to show there's any harm to children.

If LLMs were treated as a niche technology for a subset of work, instead of being shoehorned into every aspect of life without consent, you wouldn't have people ready to join the Butlerian Jihad Vanguard. There is a kind of self-centered chauvinism in the way tech people think of "work" and "use."

Genomicists on Bluesky, does anyone have experience with Pore-C? Wondering about its use for genome assembly fully based on ONT sequencing.

What worries me is there a willing participants who seem hell bent on devaluing humans.

“The deskilling, denigration, and displacement of teachers and scholars have historically been central to fascist takeovers, since educators serve as bulwarks against propaganda, anti-intellectualism, and illiteracy.” — @olivia.science www.project-syndicate.org/commentary/a...

AI does not enhance “efficiency.” AI is a permission structure for a totalizing regime of austerity and labor immiseration.

Weds: Sore throat Thurs: Wed + Sinus pressure Fri: Wed + Thur + coughing and stuffed nose + tired Sat: Cough, sneezing and ZERO sense of taste/smell! I think we all know what that is then. :/

Humanity runs on spite lmao

AI is central to this illegal war. New from me - buttondown.com/creativegood...

Behold: the first-ever list of news outlets that have banned generative AI in their reporting. As of today, this is literally information that you cannot find on Google. My goal is to fill the starter pack, so please send over suggestions with supporting evidence! go.bsky.app/8cn1XfT

Mark Zuckerberg's Pervert Glasses.

This is a common reply to concerns about GenAI research as if it were just another computational tool that saves us times from tedious tasks and whose accuracy can be rigorously quantified. It is not. GenAI research poses at least 2 serious problems... /n

And everyone is running around praising them for being "ethical" www.bloomberg.com/news/article...

I just can't imagine having this amount of self-loathing.

Interested in microbial proteins and their diversity? 🖥️🧬🦠 We have recently released the Amino Acid Sequence Toolkit (AASTK). AASTK is designed to work with the GlobDB to create and work with datasets of protein sequences. AASTK currently consists of 4 tools: - CASM - PASR - CUGO - Meta 1/

@ox.ac.uk any chance you might rethink your collaboration with OpenAI and the free access to the edu version to all staff and students now? I won't hold my breath.

www.wsj.com/livecoverage... See what I mean...

If you're quitting OpenAI's chatGPT to defect to Anthropic's Claude then you've fallen for advertising and marketing. Nothing else.

@ox.ac.uk any chance you might rethink your collaboration with OpenAI and the free access to the edu version to all staff and students now? I won't hold my breath.

So how many of my colleagues are PAYING OpenAI to use their LLM again???? You see where your money is going?

Huge news 🌍🧬 The Protist 10,000 Genomes Project is joining the Earth BioGenome Project. Protists may represent the majority of eukaryotic diversity — yet only a tiny fraction have reference genomes. Time to change that. 🚀✨ Learn more 👉 ngdc.cncb.ac.cn/p10k/ #EBP #Protists #Genomics #TreeOfLife

The people of Gorton and Denton have rejected hate. www.bbc.co.uk/news/article...

These ideas come from our forthcoming chapter in the @sfiscience.bsky.social volume The Economy as a Complex Evolving System, Part IV: “The Evolutionary Ecology of Software: Constraints, Innovation, and the AI Disruption.” 🔗https://arxiv.org/abs/2512.02953

Debates like “programming is dead,” “AI will automate X,” or the latest “vibe coding” trend all miss the point. They treat complexity as something we can engineer away—instead of recognizing the ecological forces shaping software.

Protist lovers: Please apply for a week of rhapsody! Learn by doing: MicroSEA (Microbial Sea Eukaryotes) course is a one-week, field-based summer school to train early-career researchers in the diversity, ecology, and single-cell biology of marine protists. opbc.sciencesconf.org #protistsonsky

Rob Grant, the co-creator of Red Dwarf, has died. "A great loss to his family, friends and comedy fans across the world". www.comedy.co.uk/people/news/...

Amazing! A conclusion finding in support of the very company being built to provide the AI reviews! #subtweet

This really helps with my career development review writing. Anything could really happen in the extremes! Here's hoping for extinction though hahahaha.