Matthias Blum (@matthiasblum.bsky.social)

Our latest preprint is out on bioRxiv! A collaboration between the groups of @martinsteinegger.bsky.social , David Jones and Christine Orengo, we clustered AlphaFold Database and ESMatlas, a whopping 821 million proteins! We reveal biome-specific groups & over 11k novel domain combinations.

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Metagenomic-scale analysis of the predicted protein structure universe Protein structure prediction breakthroughs, notably AlphaFold2 and ESMfold, have led to an unprecedented influx of computationally derived structures. The AlphaFold Protein Structure Database now prov... https://www.biorxiv.org/content/10.1101/2025.04.23.650224v1