Sharing our new paper where we did our sssmug protocol, found differences in GAGs and sialylation, and it matched exactly the only 2 differentially expressed glycoenzymes. #glycotime onlinelibrary.wiley.com/doi/10.1002/...

Have you ever wondered how many N-Glycans or #glycoproteins there are on cells? The numbers are massive: calculations suggest about 20 to 200 million N-glycans per human cell! Read the full blog post: research.bidmc.org/ncfg/blog/24... #glycobiology #glycotime #cells #biology

This is a fantastic day for Australian chemistry. First Australian chemistry Nobel prize since John Cornforth in 1975, but Richard Robson's work is at least as impactful. #ozchem

Super excited by our new #glycotime preprint! A long-term project from my group with awesome collaborator @elisafadda.bsky.social Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase www.biorxiv.org/content/10.1... thread below 👇

How easy is it to fudge your scientific rank? Meet Larry, the world’s most cited cat www.science.org/content/arti... "More than 130 citations in 4 years." Meow, Larry! Oh wait. “All you have to do is put some fake papers on ResearchGate.” And buy citations. Critical: Let's clean up research!

Australian Proteomics Analysis Facility (APAF) celebrating 30 year anniversary. Had a good morning on the past, present, and future of proteomics by the pioneers in the field, including Prof. Nicki Packer @sugar-princess.bsky.social, and Prof Mark Wilkins, who famously invented the word "Proteome"

When glycan recognition is linked to immune response, you need fine tuning! 😎 Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️ doi.org/10.1101/2025...

By deep characterisation of 186 N-glycan standards, we @thencfg.bsky.social have made the most comprehensive targeted LC-MS glycomic assay to date. Non-reduced native glycan analysis is key. We hope this enables anyone with QqQ and interest in #glycotime to measure specific N-glycan structures.

Resonated so well with so many speakers that it gets quoted by almost every planery talk that follows on. #Glyco27 @sugar-princess.bsky.social

Imagine if more countries fund glyco like Canada #Glyco27 #glycotime

📱 Don’t forget: our social media competition is live! Follow us and use #Glyco27 when posting on LinkedIn, X (Twitter), or Bluesky for a chance to win a prize! Let’s get the conversation going and have an amazing conference! #Glycotime #Glycoscience #Glycobiology #Canada #YEG

Congratulations to @nickescott.bsky.social on his dual MCR prize from both AGS @ozglyco.bsky.social and APS for his work on bacterial glycosylation! #glycotime

Spatial mapping of the brain metabolome lipidome and glycome #NatCommun #MassSpec www.nature.com/articles/s41...

Nice #glycotime review that pulls together the emerging story of glycosyltransferase specificity for cellular substrates chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

academic.oup.com/ecco-jcc/art... Happy to share our most recent publication on how T cells glycosylation mediates #IBD progression to colorectal cancer defining the risk of colitis-associated cancer. #glycotime Great work @eduardalgomes.bsky.social @i3suporto.bsky.social @GlycanTrigger

There are great conferences and science in the US, but with the way things are right now, it’s too risky to attend.

Just out by Shelley Jager: rdcu.be/edEnO. One of the fastest & deepest plasma glycoproteomics studies. Take home message; we even detect glycosylated cytokines and chemokines, but also still need better software. #glycotime @utrechtuniversity.bsky.social @bijvoet-centre.bsky.social

Happy to share this new #glycotime work with collaborator Tony Wyss-Coray, led by grad student Sophia Shi, mucin loss at the BBB is associated with aging and cognitive decline, can be reversed by restoration with with gene therapy. Aging is a mucinopathy! www.nature.com/articles/s41...

Picture this: your fav protein-protein interaction is *entirely* dependent on, 1) glycans 💥 2) the type of glycans 🤯💜 Check out this doi.org/10.1016/j.jb... 🔝 #glycotime fresh off the press in JBC led by Nicki Packer and Len Harrison 🇦🇺 + us 🇮🇪🇬🇧 + @ethangbaus.bsky.social 🇦🇺 🧵1/5

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments #JVisExp #MassSpec app.jove.com/t/67405/glyc...

A POGase is a huge advance in the glycomics field, which has typically relied on chemical or incomplete enzymatic releases (no Sia). Expect a lot of multi-omic studies enabled by this (N-glycomics, O-glycomics, and proteomics) since the peptide backbone is left intact. www.nature.com/articles/s41...

🎉Announcing our ANZSMS 2025 Medalists 🎉 Congratulations to Prof Nicki Packer from Macquarie University and A/Prof Shane Ellis from University of Wollongong! Join us at AUS-omics from May 18 - 21 to celebrate this wonderful achievement! 🏆 Read about our medalists here 👉 mailchi.mp/6c90f3d41712...

A robust glycomic study, can’t critique any aspect of the sample QC or methods used. Really nice work. #glycotime #TeamMassSpec

Had a great time at GlycoBioTec2025 (www.mpi-magdeburg.mpg.de/glycobiotec2...), held once every 2 years, with a good amount of industry participants. Furthermore, food at Harnack Haus is fabulous!

Check it out, powerful new method for optical imaging of the live ECM, from @hhmijanelia.bsky.social Group Leader Kayvon Pedram #proudofalumni #glycotime www.nature.com/articles/s41...

Our latest work on Siglec binding to sulfated glycans. Great help: @khookh.bsky.social, @pengwu.bsky.social ,@raflynn5.bsky.social. Fom 1st PhD graduate of the lab (Jaesoo Jung) and help from Edward, Zeinab, Jhon, Kelli, @tayloregray.bsky.social, and Chris from my lab. pubs.acs.org/doi/10.1021/...

Glycomics quantitation has a lot of nuances, and this paper discusses a lot about it, and potentially has a solution for it. Congrats to @dbojar.bsky.social and co.! #glycotime www.nature.com/articles/s41...

Inhibition of chondroitin sulphate-degrading enzyme Chondroitinase ABC by dextran sulphate #glycotime #GlycoconjugateJournal

Time to share our organelle proteome paper out in @cellcellpress.bsky.social: doi.org/nzwz We created a spatial map of human cells using organelle immunoprecipitation at scale. Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/ 1/3 🧪

It’s #glycotime Fucosyltransferases FUT10 and FUT11 are protein O-fucosyltransferases (POFUTs) modifying proteins with elastin microfibril interface (EMI) domains. Curious to know the function(s) of O-fucosylating EMI domains www.nature.com/articles/s41...

First Bluesky post! Personal highlight of 2024, multi-glycomics method development that extracts multiple glycan types from the same sample for in-depth characterisation. #glycotime pubs.acs.org/doi/10.1021/...